2003-2004CNS Pharmacology

Review

April 18, 202308:30 PM

Acetaminophen

Analgesic, Antipyretic

Adrenocorticotropin(ACTH)

Anterior pituitary hormoneAnticonvulsant

Stimulates synthesisand release of cortisol

Alfentanil

OpioidGeneral anaesthetic

Intravenous anaesthetic

Amantadine

AntiviralAntiparkinson

Treatment of Influenza A Inhibits replication

at the stage of uncoatingInhibits dopamine release

Amitriptyline

Tricyclic antidepressant (TCA)

Amphetamine

Indirect sympathomimeticDrug of abuse

ADD treatmentStimulant

Atropine

Anticholinergic

AntimuscarinicTreatment for bradycardia,

diarrhea, cholinesterase poisoning

Baclofen

Skeletal muscle relaxantAnxiolytic

GABAB agonist

Benztropine

AnticholinergicAntiparkinson

Muscarinic receptor antagonist

Bethanecol

Cholinomimetic

Muscarinic agonistInduces defecation and

urinationBronchoconstrictor

Bromocriptine

Antiparkinson

Dopamine (D2) agonistInhibits prolactin release

Brupropion

Second generation antidepressant

Buprenorphine

Opioid

Partial agonist

Buspirone

Sedative/hypnoticAnxiolytic

Butorphanol

OpioidAnalgesic

receptor partial agonistor antagonist

Carbamazepine

Anticonvulsant

Carbidopa

Antiparkinson

Peripheral dopa decarboxylase inhibitor

Celecoxib

NSAIDAnti-inflammatory

Cyclooxygenase 2 (COX-2) inhibitor

Chloral hydrate

Sedative/HypnoticGeneral anaesthetic

Acts on GABAA receptor complexSimilar to barbiturates

Chlordiazepoxide

Sedative/hypnoticAnxiolytic

Benodiazepine Acts on GABAA receptor

complex

Chlorpromazine

Antipsychotic

Phenothiazine

Clozapine

Antipsychotic

Cocaine

Indirect sympathomimeticDrug of abuse

Topical anaesthetic

StimulantLocal anaesthetic

Codeine

OpioidAnalgesic

Weak agonist

Dantrolene

Skeletal muscle relaxant

Ryanodine receptor antagonistTreatment for malignant hyperthermia

Deprenyl/selegiline

Antiparkinson

Monoamine oxidase B inhibitor(MAO-I)

Potentiates effects of L-Dopa

Desipramine

Tricyclic antidepressant (TCA)

Dextromethorphan

Opioid

Antitussive

Diazepam

Sedative/hypnoticAnxiolytic

Anticonvulsant

Benzodiazepine Acts on GABAA receptor complex

Diflunisal

NSAIDAnalgesic, Anti-inflammatory

Antipyretic

Cyclooxygenase inhibitor

Diphenoxylate docusate

Antidiarrheal

Opiate

Enflurane

General anaesthetic

Inhaled anaesthetic

Entacapone

Antiparkinson

Peripheral catechol-o-methyltransferase inhibitor

Ephedra(Ma Huang)

Dietary supplement

Amphetamine-like stimulant

Ethanol

Drug of abuse

Sedative

Ethosuximide

Anticonvulsant

Etomidate

General anaesthetic

Intravenous anaesthetic

Fentanyl

OpioidAnalgesic

receptor agonist

Flumazenil

Benzodiazepine antagonist

Acts on GABAA receptor complex

Fluoxetine

Antidepressant

Selective serotonin reuptake inhibitor (SSRI)

Flurazepam

Sedative/Hypnotic

Benzodiazepine Acts on GABAA receptor

complex

Ginko biloba

Dietary supplement

Treatment of Alzheimer symptoms

Glutethimide

Sedative/Hypnotic

Haloperidol

Antipsychotic

Halothane

General anaesthetic

Inhaled anaesthetic

Heroin

Drug of abuse

Opioid

Imipramine

Indirect sympathomimeticTricyclic antidepressant (TCA)

Antimicturant

Indomethacin

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitorTocolytic

Uterine relaxant

Isoflurane

General anaesthetic

Inhaled anaesthetic

Kava kava

Dietary supplement

Stress relief andtreatment of insomnia

Ketamine

General anaestheticDrug of abuse

Sedative

Ketoprofen

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

Levodopa

Antiparkinson

Dopamine precursor

Lidocaine

Class I antiarrhythmicLocal anaesthetic

Na+ channel blocker(activated and inactivated channels)

Lithium

Antidepressant

Used to treatmanic/depressive disorder

Loperamide

Antidiarrheal

Opiate

Lorazepam

AnxiolyticAnticonvulsant

BenzodiazepineActs on GABAA receptor complex

Lysergic acid diethylamide

(LSD)

Drug of abuse

Hallucinogen

Marijuana

Drug of abuse

Cannabinoid

Meperidine

Opioid analgesic

receptor agonist

Mepivacaine

Local anaesthetic

Meprobamate

Sedative/hypnoticAnxiolytic

Meclofenamate

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

Metamphetamine

Drug of abuse

Stimulant

Methadone

Opioid

receptor agonist

Morphine

OpioidAnalgesic

receptor agonist

Nalbuphine

Opioid antagonist

receptor antagonist

Nalmefene

Opioid antagonist

Nalorphine

Opioid antagonist

Naloxone

Opioid antagonist

Naltrexone

Opioid antagonist

Naproxen

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

Neostigmine

Anticholinesterase

VasodilatorTreatment for myaesthenia gravisPromotes defecation and urination

Bronchoconstrictor

Nicotine

CholinomimeticDrug of abuse

Nicotinic receptor agonist(skeletal muscle contraction)

StimulantSmoking cessation medication

Nitrous oxide

General anaesthetic

Inhaled anaesthetic

Non-steroidalAnti-inflammatory Drugs

(NSAIDs)

Analgesic, Anti-inflammatory, Antipyretic

Cyclooxygenase inhibitors

Nortriptyline

Tricyclic antidepressant (TCA)

Oxazepam

Sedative/hypnoticAnxiolytic

BenzodiazepineActs on GABAA receptor complex

Oxybutinin

Anticholinergic

Muscarinic receptor antagonistPrevents urination

Oxycodone

Analgesic

Opioid agonist

Paraldehyde

Sedative/Hypnotic

Pentazocine

Opioid analgesic

receptor partial agonist or antagonist

Pentobarbital

Sedative/Hypnotic

Barbiturate

Phencyclidine (PCP)

Drug of abuse

Hallucinogen

Phenobarbital

Sedative/HypnoticAnticonvulsant

Barbiturate

Phenytoin

AnticonvulsantClass I antiarrhythmic

Na+ channel blocker(inactivated channels)

Piroxicam

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

Pramipexole

Antiparkinson

Dopamine agonist (non-ergot)

Primidone

Anticonvulsant

Procaine

Local anaesthetic

Propofol

General anaesthetic

Intravenous anaesthetic

Resperidone

Antipsychotic

Ropinirole

Antiparkinson

Dopamine agonist (non-ergot)

Sertraline

Antidepressant

Selective serotonin reuptake inhibitor (SSRI)

Sildenafil

Vasodilator

Promotes erection

St. John’s Wort

Dietary supplement

Antidepressant

Sufentanil

OpioidGeneral anaesthetic

Intravenous anaesthetic

Sulindac

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

Temazepam

Sedative/Hypnotic

BenzodiazepineActs on GABAA receptor complex

Tetracaine

Local anaesthetic

Thiopental

General anaesthetic

Ultra-short-acting barbiturate

Thioridazine

Antipsychotic

Phenothiazine

Thiothixene

Antipsychotic

Tolterodine

Anticholinergic

Muscarinic receptor antagonistPrevents urination

Tranylcypromine

Antidepressant

Monoamine oxidase inhibitor (MAO-I)

Triazolam

Sedative/Hypnotic

BenzodiazepineActs on GABAA receptor complex

Trifluoperazine

Antipsychotic

Phenothiazine

Trihexyphenidyl

Antiparkinson

Antimuscarinic

Valproic acid

Anticonvulsant

Vigabatrin

Anticonvulsant

Irreversible GABA aminotransferase inhibitor

Zolpidem

Sedative/Hypnotic

Non-benzodiazepine