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2016 West Virginia Overdose Fatality Analysis:

Healthcare Systems Utilization, Risk Factors, and Opportunities for Intervention

Christina Mullins, DirectorOffice of Maternal, Child and Family Health

Bureau for Public HealthDecember 21, 2017

Drug Overdose Rates by State

1

US Resident Overdose Deaths by State, 2015

West Virginia vs. United States

2

11.512.9

15.1

18.822.3

20.422.4

25.725.9

28.9

36.3

32.0 32.2

35.5

41.5

6.88.2 8.9 9.4 10.1

11.5 11.9 11.9 11.9 12.313.2 13.1 13.8

14.716.3

0

5

10

15

20

25

30

35

40

45

2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Per 100,000

2001-2015 Resident Drug Overdose Mortality RateWest Virginia and United States

WV

Data Source: WV Health Statistics Center, Vital Surveillance System and CDC Wonder.Rates are adjusted by age to the 2000 US Standard Million.

Purpose

3

Create a model

Identify risk factors

Identify opportunities for intervention

Methods

4

881

Preliminary Occurrence

Deaths

830

Preliminary Resident Deaths

(Matched against death records, CSMP,

Medicaid, EMS, BBHHF, and Corrections)

Interactions with Health Systems

5

Healthcare systems included BBHHF, EMS, and CSMP. Neither Medicaid or Corrections were included.

• 81% of decedents interacted with one or more systems.• Just under 40% of decedents interacted with only one system.

22%38%

30%

10%

78%

Males: Interactions with Healthcare Systems

None One Two Three

13%

39%

30%

18%

87%

Females: Interactions with Healthcare Systems

None One Two Three

Number of Drugs at Time of Death

6

• Females were more likely than males to have more than one drug in their system at their time of death.

One 10%

Two 27%

Three28%

Four17%

Five10%

Six Plus8%

Females: Number of Drugs at Time of Death

One 16%

Two 31%

Three25%

Four 14%

Five10%

Six Plus4%

Males: Number of Drugs at Time of Death

Drugs at Time of Death

7

Diversion

8

8%

23%

31%

20%

11%

1%

8%

24%

28%

15%

10%

2%

0%

5%

10%

15%

20%

25%

30%

35%

15-24 25-34 35-44 45-54 55-64 65+

Decedents Positive for a Controlled Substance at

Death but no Prescription by Gender and Age

Male Female

A total of 272 decedents (33%) tested positive for a controlled substance, but had no prescription at their time of death.

Decedents with CSMP Interaction

9

91%

9%

Decedents with CSMP Interaction

CSMP History No CSMP History

The West Virginia Board of Pharmacy’s Controlled Substances Monitoring Program (CSMP) documents the dispensing of Schedule II-IV controlled substances.

CSMP History at Point in Time Intervals

10

506

348

323

289

245

199

253

197

182

162

156

133

0 50 100 150 200 250 300 350 400 450 500 550

Ever

12 month

9 month

6 month

3 month

30 Day

CSMP History at Point in Time Intervals before Death by Gender

Females Males

Nearly half (49%) of all female decedents filled a prescription within 30 days of death, compared to 36% of males.

Number of Prescriptions by Drug Category

11

0

100

200

300

400

500

12 Months 9 Months 6 Months 3 Months 1 Month

Number of Prescriptions Before Death by Drug Category

Opioid Benzodiazepine Stimulant Other

Opioids and benzodiazepines were the most common controlled substance prescriptions filled by decedents in the 12 months prior to their death.

Prescriber and Pharmacy Utilization

12

• Decedents were three times more likely to have three or more prescribers as compared to the overall CSMP population for 2016 (9% versus 3%).

• Decedents were more than 70 times likely to have prescriptions at four or more pharmacies compared to the overall CSMP population for 2016 (7% vs. 0.1%).

EMS Administered Naloxone

13

29%

49%

8%14%

71%

Decedents with EMS Administered Naloxone

No Interaction with EMS No Naloxone

Naloxone > 48 Hrs Before Death Naloxone < 48 Hrs Before Death

There may be a disparity in the overall emergency response to West Virginians older than 65 that warrants further study.

Medicaid Eligibility

14

71%

29%

Medicaid Eligibility atAny Time 12 Months Prior to Death

Medicaid No Medicaid

According to the Kaiser Foundation, only 23% of West Virginia’s overall adult population ages 19-64 have Medicaid.

Medicaid Major Diagnostic Categories

15

51 4944

4036

64 63

5246

5156 54

4743 42

0

20

40

60

80

Symptoms,Signs, and Ill-

DefinedConditions

Mental Disorders Diseases of theMusculoskeletal

System andConnective

Tissue

Injury andPoisoning

SupplementaryClassification of

FactorsInfluencing

Health Statusand Contact withHealth Services

Major Diagnostic Categories with the Most Medicaid Eligible Decedents

Represented

Males Females Total

Medicaid Utilization

16

85%

15%

Percentage of Decedents Utilizing Medicaid within 12 Months Prior to

Death

Interaction

No interaction

Excludes claims within < 48 hours of death.

Low (≤30)30%

Medium (31-60)

20%

High (61-90)13%

Very High (>90)37%

Number of Medicaid Claims Prior to Death

Excludes pharmacy claims and claims within < 48 hours of death.

Utilization of Medicaid for Emergency Department (ED) Visits

17

9%

22%

69%

Emergency Department Utilization Among Decedents

within 48 hrs

Only 1 visit

2 or more visits

81%

12%3% 4%

Emergency Department Utilization by Number of Visits

between 1-5

between 6-10

between 11-15

>15

68%

32%

Medicaid Decedents with an ED Visit within 12 Months of Death

Yes

No

Medical services have the potential to reach a significant portion of individuals at risk of fatal overdose. Implementation of the Medicaid 1115 Waiver will expand opportunities for treatment and recovery services.

Corrections History by Gender

18

44%

43%

13%

56%

Corrections History by Gender

None Males with History Females with History

Officials from the WV Department of Military Affairs and Public Safety reported that there is not a uniform strategy for identifying how people with a substance abuse disorder are referred to services in their community.

Death After Incarceration

19

464 Interacted with

Corrections (Jail, Prison, Parole)

157 One Contact with Corrections

in the 12 Months Prior to Death

42 (27%) Died within 30 days of the Last Corrections Contact (Regional jail was the last

contact for the majority of decedents (88%) with a

corrections history.)

• 46% with some high school education died within 30 days.

• 32% of decedents that were never married died within 30 days.

Select High Risk Factors

20

Males

(67%)

35-54 Years of Age

(54%)

HS Education or Less

(79%)

Unmarried

(75%)

Blue Collar Occupations

Decedents by Industry Type

21

Recommendations for Healthcare Providers

22

• Be prepared to offer screening, referral, and/or treatment.

• Continuing education opportunities that help identify risk factors for overdose death and retain individuals in substance abuse treatment.

• Require prescribers to run a CSMP report on each patient prior to prescribing any Schedule II drugs, any opioids, and any benzodiazepines.

• Prescribers should consider offering naloxone for individuals at increased risk for opioid overdose.

CSMP Recommendations

23

• Enhance CSMP Advisory Committee legislation to identify abnormal or unusual prescribing and dispensing patterns and to permit sharing this data with appropriate professional licensing boards and other agencies.

• Develop CSMP policies and procedures for proactive reports to alert prescribers about the increased risk of overdose and potential misuse or diversion for those individuals known to the CSMP.

Other Recommendations

24

• Corrections officials should work with judges to assure naloxone availability, treatment referral, and peer supports at release of incarceration.

• Healthcare providers and the public may benefit from education regarding overdose signs and symptoms. This education should include information specific to individuals older than 65 years to increase the chance that someone will call emergency services and that appropriate administration of naloxone is offered.

Contact

Christina Mullins, Director

Office of Maternal, Child and Family Health

West Virginia Department of Health and Human Resources

Bureau for Public Health

350 Capitol Street, Room 427

Charleston, WV 25301

Email: Christina.R.Mullins@wv.gov

Phone: 304-356-4392

25