3T NeuroImaging

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3T NeuroImaging. Primate Chair. Jennifer Pryweller. Sponsor: Dr. Calum Avison, Vanderbilt University Institute of Imaging Science. Philips 3T Achieva. Visual Cortex. fMRI brain scan BOLD. Objectives. CPU Cortex/LabView. monitor. visual task. IR camera. audio tone. juice - PowerPoint PPT Presentation

transcript

Philips 3T Achieva

Visual Cortex

fMRI brain scan BOLD

MONK

RF signal

audiotone

juicecontroller

juicedispenser

solenoidEMG neuron

APfMRI BOLD

visualtask

IRcamera

CPUCortex/LabView

monitor

• Non-human primate of choice:

• anatomical & physiological likeness

• ease of maintaining & breeding in captivity

• No harm / minimize discomfort

• IACUC (Institutional Animal Care and Use Committee)

• IRB (Institutional Review Board) approval • Ethics Research Training (exam #1102055)

Wim Vanduffel (2001)

Mark Pinsk (2004)

Crist Instruments (current)

Improvements: mechanical design, materials selection, audio reinforcement, component

integration

General Property ASTM Test Typical Value

Specific Gravity D792 1.2

Tensile Strength Yield D638 8,900 - 9,000

Tensile Modulus D638 340,000

Izod Impact - Notched D256 12-16

Hardness - Rockwell D785 M70

Deflection Temp @ 264psi D648 270

Deflection Temp @ 66 psi D648 280

Co. Thermal Expansion D696 3.7X10-5

General Property ASTM Test Typical Value

  Specific Gravity  D792 1.19

  Tensile Strength Yield D638 10,000

  Tensile Modulus D638 400,000

  Izod Impact - Notched D256 0.4

  Hardness - Rockwell D785 M94

  Deflection Temp @ 264psi D648 210

  Deflection Temp @ 66 psi D648 239

  Co. Thermal Expansion D696 3.4X10-5

Polycarbonate material properties

Acrylic material properties

Max. Available Diameter Polycarbonate AcrylicApplied Plastics Co 8” 8”Industrial Plastic Supply, Inc 4” 24”Inplex LLC 3.5” n/aMcMaster-Carr** 8” (± .04) 18” (± .08)Modern Plastics 8” (± .03) 6”Scandia Plastics Inc 8” n/aUS Plastics 4” 12”

Tubing Availability

**preferred company

ACRYLIC TUBE

outside diameter: 15”16” 18”

Length 24"Length Tolerance +.25"Inside Diameter 14-3/4"Outside Diameter 15"Outside Diameter Tolerance ±.08"Wall Thickness .125"Wall Thickness Tolerance ±.02"Acrylic Material Cast AcrylicPart No. 84865K317

Cost: $311.42

Length 24"Length Tolerance +.25"Inside Diameter 15-1/2"Outside Diameter 16"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.025"Acrylic Material Cast AcrylicPart No. 84865K418

Cost: $438.64 

Length 48"Length Tolerance +.25"Inside Diameter 15-1/2"Outside Diameter 16"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.018"Acrylic Material Cast AcrylicPart No. 84865K438

Cost: $871.70 

Length 48"Length Tolerance +.25"Inside Diameter 17-1/2"Outside Diameter 18"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.018"Acrylic Material Cast AcrylicPart No. 84865K439

Cost: $884.35

Length 24"Length Tolerance +.25"Inside Diameter 17-1/2"Outside Diameter 18"Outside Diameter Tolerance ±.08"Wall Thickness .25"Wall Thickness Tolerance ±.025"Acrylic Material Cast AcrylicPart No. 84865K419

Cost: $444.95

Source: www.mcmaster.com

grate/perforated slab of steel or aluminum

disposable, removable lining across bottom

vertices glued and waterproof

recessed ¼”, 20 thread screws

rapid prototyping

machine

¼”, 20 thread, nylon screws

aluminum, brass, plastic stainless steel

appr

oxim

ate

piano hinge along tube (?)

= isocenter, 23.255cm from base

Philips 3T Achieva

8.255

45.72

15.00

26.942

23.255

3.96941.751

NOT DRAWN TO SCALE

Based on our measurements of the bohr…

Philips 3T Achieva

NOT DRAWN TO SCALE

Philips 3T Achieva

NOT DRAWN TO SCALE

• Mechanical design model

• Macaque measurements: 6.5-8.5kg, 28-32” prone

• Chair: diameter, landmark, loading, attach, packing

• Bohr measurements

• final design revisions• machine the chair• Mock scanner environment• Monkey training• RF coil selection & construction• Functional components: QFDs & selection