Post on 10-Apr-2015
transcript
ACUTE LEUKEMIA CLINICAL TRIALS
DISCLAIMER:- The Following Clinical Trials are from our 2005 review and are NOT in our current reviews. They are listed only as examples of what is written in our clinical trials reviews.
rHuEPO and treatment outcomes: the clinical experience.
Hudis CA, Van Belle S, Chang J, Muenstedt K.
Breast Cancer Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA. hudisc@mskcc.org
Increasingly, anemia is being recognized as a negative prognostic and predictive factor for patients undergoing chemotherapy, radiation therapy, or a combination of these treatment modalities. The results of clinical studies have shown correlations between anemia and shorter survival times in patients with a wide variety of solid tumors and hematologic malignancies, including lung, ovarian, breast, and head/neck cancers, non-Hodgkin's lymphoma, Hodgkin's disease, Waldenstrom's macroglobulinemia, and chronic lymphocytic leukemia. Also, anemia has been shown to predict treatment response in patients with ovarian, cervical, and urothelial cancers, mantle cell lymphoma, and chronic lymphocytic leukemia, as well as refractory/relapsed acute myelogenous leukemia. Based on the presumed causal relationship between anemia and poor patient outcome, several studies have examined the influence of epoetin alfa (a recombinant human erythropoietin) on outcomes in anemic patients undergoing cancer treatment. The results of these studies have been encouraging, with indications of greater locoregional tumor control and higher response rates in epoetin alfa-treated patients. Additionally, epoetin alfa therapy, by correcting anemia, has been shown to improve a patient's energy level, ability to perform daily activities, and overall quality of life (QOL). Such effects not only enhance a patient's general well-being, but may also increase their tolerance of, and willingness to undergo, full courses of their cancer therapy in a timely manner. These findings support the use of epoetin alfa to achieve gains in QOL and cancer treatment outcomes in anemic cancer patients and suggest that additional studies be conducted to further investigate the potential benefits of this agent in regard to improved outcomes.
SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes.RATIONALE: Drugs used in chemotherapy, such as SB-715992, work in different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of SB-715992 in treating patients who have acute leukemia, chronic myelogenous leukemia, or advanced myelodysplastic syndromes. California City of Hope Comprehensive Cancer Center, Duarte, California, 91010-3000, United States; Recruiting Clinical Trials Office - New Patient Services 800-826-4673 becomingapatient@coh.org
Ohio Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, 44106-5055, United States; Recruiting Brenda W. Cooper, MD 216-844-3213 bxc12@po.cwru.edu
Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia.RATIONALE: Drugs used in chemotherapy such as sirolimus use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of sirolimus in treating young patients who have relapsed or refractory acute leukemia or non-Hodgkin's lymphoma. Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States; Recruiting Susan Rheingold, MD 215-590-2801 rheingold@email.chop.edu
Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia.RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining flavopiridol and cytarabine with mitoxantrone in treating patients who have acute leukemia. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, 21231, United States; Recruiting Judith E. Karp, MD 410-502-7726
3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia.RATIONALE: Drugs used in chemotherapy, such as fludarabine, work in different ways to stop cancer cells from dividing so they stop growing or die. 3-AP may help fludarabine kill more cancer cells by making them more sensitive to the drug. PURPOSE: This phase I trial is studying the side effects and best dose of fludarabine when given together with 3-AP in treating patients with relapsed or refractory acute leukemia, chronic leukemia, or high-risk myelodysplastic syndrome. Georgia Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia, 30342-4777, United States; Recruiting Lawrence E. Morris, MD 404-255-1930 lmorris@bmtga.com
Maryland Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, 21201, United States; Recruiting Ivana Gojo, MD 410-328-2565
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, 21231, United States; Recruiting Judith E. Karp, MD 410-502-7726
Texas
MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United States; Recruiting Francis J. Giles, MD 713-792-7305 fgiles@mdanderson.org
Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma, Acute Myeloid Leukemia.RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy in treating patients who have acute myeloid leukemia.Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, 02115, United States; Recruiting F. Stephen Hodi, MD 617-632-5053
Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Acute Lymphoblastic Leukemia.
RATIONALE: Chemotherapy drugs, such as ifosfamide, carboplatin, and etoposide, work in different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining ifosfamide, carboplatin, and etoposide with rituximab may kill more cancer cells.
PURPOSE: This phase II trial is studying how well rituximab together with ifosfamide, carboplatin, and etoposide works in treating young patients with recurrent or refractory acute lymphoblastic leukemia.
Alabama University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, 35233, United States; Recruiting Robert P. Castleberry, MD 205-939-9285 rcastleberry@peds.uab.edu
University of South Alabama Cancer Research Institute, Mobile, Alabama, 36604, United States; Recruiting Felicia L. Wilson, MD 251-405-5115 fwilson@usouthal.edu
Arizona Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, 85724, United States; Recruiting Rochelle Bagatell, MD 520-626-4851
Phoenix Children's Hospital, Phoenix, Arizona, 85016, United States; Recruiting Jessica Boklan, MD 602-546-0920
Arkansas
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72205, United States; Recruiting David L. Becton, MD 501-320-5650
California Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center, Orange, California, 92868, United States; Recruiting Stanley Calderwood, MD 714-456-6615 scalderw@uci.edu
Children's Hospital and Health Center, San Diego, San Diego, California, 92123-4282, United States; Recruiting Richard Kadota, MD 858-966-5811
Children's Hospital and Research Center at Oakland, Oakland, California, 94609-1809, United States; Recruiting James H. Feusner, MD 510-428-3000 jfeusner@mail.cho.org
Children's Hospital Central California, Madera, California, 93638-8762, United States; Recruiting Vonda Lee Crouse, MD 559-353-5480 vcrouse@childrenscentralcal.org
Children's Hospital Los Angeles, Los Angeles, California, 90027-0700, United States; Recruiting Paul S. Gaynon, MD 323-669-2163 pgaynon@chla.usc.edu
Children's Hospital of Orange County, Orange, California, 92868, United States; Recruiting Wei-Ping Violet Shen, MD 714-516-4348 vshen@choc.org
General Robert Huyser Cancer Center at David Grant Medical Center, Travis Air Force Base, California, 94535, United States; Recruiting Peter J. Chenaille, MD 707-423-7176
Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California, 90801-1428, United States; Recruiting William Mark Roberts, MD 562-933-8600 wmroberts@memorialcare.org
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, 90095-1781, United States; Recruiting Stephen A. Feig, MD 310-825-5268
Kaiser Permanente Medical Center - Sacramento, Sacramento, California, 95825, United States; Recruiting Vincent A. Kiley, MD 916-973-7331 vincent.kiley@kp.org
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, 95051-5386,
United States; Recruiting Carolyn Lucille Russo, MD 408-236-5028 carolyn.l.russo@kp.org
Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego, California, 92120, United States; Recruiting Wellington Loh, MD 619-516-6144
Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California, 92354, United States; Recruiting Antranik Bedros, MD 909-558-8626 abedro@ahs.llumc.edu
Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California, 94304, United States; Recruiting Neyssa M. Marina, MD 650-723-5535 neyssa.marina@stanford.edu
Rebecca and John Moores UCSD Cancer Center, La Jolla, California, 92093-0658, United States; Recruiting Richard Kadota, MD 858-657-7020
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles, California, 90048, United States; Recruiting Moshe Arditi, MD 310-423-4471
Santa Barbara Cottage Hospital, Santa Barbara, California, 93102, United States; Recruiting Felicity Hodder, MD 805-682-7111 fhodder@cottagehealthsystem.org
Southern California Permanente Medical Group, Downey, California, 90242, United States; Recruiting Willye B. Powell, MD 562-803-2472
Sutter Cancer Center, Sacramento, California, 95816, United States; Recruiting Yisheng Lee, MD, PhD, MBA 916-733-1757
UCSF Comprehensive Cancer Center, San Francisco, California, 94143, United States; Recruiting Katherine K. Matthay, MD 415-476-3831
University of California Davis Cancer Center, Sacramento, California, 95817, United States; Recruiting Theodore Zwerdling, MD 916-734-2781 theodore.zwerding@ucdmc.ucdavis.edu
Colorado Children's Hospital Cancer Center, Denver, Colorado, 80218, United States; Recruiting Roger Howard Giller, MD 303-861-6892 giller.roger@tchden.org
Presbyterian - St. Luke's Medical Center, Denver, Colorado, 80218, United States; Recruiting Stephen R. Palmer, MD 719-471-2462
Connecticut Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center, Farmington, Connecticut, 06360-7106, United States; Recruiting Arnold J. Altman, MD 860-545-9630
Yale Comprehensive Cancer Center, New Haven, Connecticut, 06520-8064, United States; Recruiting Jack van Hoff, MD 203-785-4640 jack.vanhoff@yale.edu
Delaware Alfred I. duPont Hospital for Children, Wilmington, Delaware, 19899, United States; Recruiting Rita S. Meek, MD 302-651-5502 rmeek@nemours.org
District of Columbia Children's National Medical Center, Washington, District of Columbia, 20010-2970, United States; Recruiting Nita Louise Seibel, MD 202-884-2144 nseibel@cnmc.org
Lombardi Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, 20007, United States; Recruiting Aziza Shad, MD 202-444-2224 shada@georgetown.edu
Florida All Children's Hospital, St. Petersburg, Florida, 33701, United States; Recruiting Jerry L. Barbosa, MD 727-892-4231 barbosaj@allkids.org
Baptist-South Miami Regional Cancer Program, Miami, Florida, 33176-2197, United States; Recruiting Doured Daghistani, MD 786-596-1960
Broward General Medical Center, Fort Lauderdale, Florida, 33316, United States; Recruiting Rudolph R. Roskos, MD 954-355-4527 rroskos@nbhd.org
Children's Hospital of Southwest Florida, Fort Myers, Florida, 33908, United States; Recruiting Emad K. Salman, MD 239-432-3333 emad.salman@leememorial.org
Florida Hospital Cancer Institute, Orlando, Florida, 32804, United States; Recruiting Jane Crofton, RN, BSN, OCN 407-303-2090
Jackson Memorial Hospital, Miami, Florida, 33136, United States; Recruiting Stuart R. Toledano, MD 305-585-5635 stoledan@med.miami.edu
Joe DiMaggio Children's Hospital at Memorial, Hollywood, Florida, 33021, United States; Recruiting Iftikhar Hanif, MD 954-986-2234 ifhanif@aol.com
Miami Children's Hospital, Miami, Florida, 33155, United States; Recruiting Enrique A. Escalon, MD 305-666-6511
Nemours Children's Clinic, Jacksonville, Florida, 32207, United States; Recruiting Eric Sandler, MD 904-390-3793 esandler@nemours.org
Nemours Children's Clinic-Orlando, Orlando, Florida, 32806, United States; Recruiting Vincent F. Giusti, MD 407-650-7230
Sacred Heart Children's Hospital, Pensacola, Florida, 32504, United States; Recruiting John F. Kelleher, MD 850-505-4798 jfkelleh@neumous.org
Shands Cancer Center at the University of Florida Health Science Center, Gainesville, Florida, 32610-0296, United States; Recruiting Stephen P. Hunger, MD 352-392-5633 hungersp@peds.ufl.edu
St. Joseph's Children's Hospital, Tampa, Florida, 33677-4227, United States; Recruiting Cameron K. Tebbi, MD 813-870-4252 cameron.tebbi@baycare.org
St. Mary's Hospital, West Palm Beach, Florida, 33407, United States; Recruiting Narayana Gowda, MD 561-840-6125 doctorgowda@hotmail.com
Georgia AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus, Atlanta, Georgia, 30342, United States; Recruiting Howard M. Katzenstein, MD 404-785-0853 howard.katzenstein@choa.org
Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah, Georgia, 31405, United States; Recruiting Tribhawan S. Vats, MD 912-350-8194 vatsri@memorialhealth.com
MBCCOP-Medical College of Georgia Cancer Center, Augusta, Georgia, 30912-4000, United States; Recruiting Roger A. Vega, MD 706-721-3626
Medical Center of Central Georgia, Macon, Georgia, 31201, United States; Recruiting Hassan Dannawi, MD 478-633-1104 dannawi.hassan@mccg.org
Hawaii
Cancer Research Center of Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting Robert Warren Wilkinson, MD 808-586-2979
MBCCOP - Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting Brian F. Issell, MD 808-586-3015 brian@crch.hawaii.edu
Tripler Army Medical Center, Honolulu, Hawaii, 96859-5000, United States; Recruiting Braden Alan Shoupe, MD 808-433-6057
Idaho Mountain States Tumor Institute - Boise, Boise, Idaho, 83712, United States; Recruiting J. Martin Johnston, MD 208-381-2782 johnstom@slrmc.org
Illinois Advocate Hope Children's Hospital, Oak Lawn, Illinois, 60453, United States; Recruiting Sharad N. Salvi, MD 708-346-4094 sharad.salvi@advocatehealth.com
Children's Memorial Hospital - Chicago, Chicago, Illinois, 60614, United States; Recruiting Susan Lerner Cohn, MD 773-880-4562
Lutheran General Cancer Care Center, Park Ridge, Illinois, 60068-1174, United States; Recruiting Jong-Hyo Kwon, MD 847-723-5962 jong-hyo.kwon_md@advocatehealth.com
Rush University Medical Center, Chicago, Illinois, 60612, United States; Recruiting Allen D. Korenblit, MD 312-942-5983 akorenbl@rush.edu
Saint Jude Midwest Affiliate, Peoria, Illinois, 61637, United States; Recruiting John A. McCallister, MD 309-624-4945 john.mccallister@stjude.org
Southern Illinois University School of Medicine, Springfield, Illinois, 62794-9658, United States; Recruiting Gregory Brandt, MD 217-545-5817 gbrandt@siumed.edu
University of Chicago Cancer Research Center, Chicago, Illinois, 60601, United States; Recruiting James B. Nachman, MD 773-702-6808
University of Illinois Medical Center, Chicago, Illinois, 60612, United States; Recruiting Mary Lou Schmidt, MD 312-996-6143 mls3@uic.edu
Indiana Riley Children Cancer Center at Riley Hospital for Children, Indianapolis, Indiana, 46202-5225, United States; Recruiting Robert Fallon, MD, PhD 317-274-8784 rfallon@iupui.edu
St. Vincent Hospitals and Health Care Centers, Indianapolis, Indiana, 46260, United States; Recruiting Randy Alan Hock, MD, PhD, MMM 317-338-4673
Iowa Blank Children's Hospital, Des Moines, Iowa, 50308, United States; Recruiting Torrey Leighton Mitchell, MD 515-241-8912 mitchetl@ihs.org
Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa, 52242-1009, United States; Recruiting Raymond Tannous, MD 319-356-1905
John Stoddard Cancer Center at Iowa Methodist Medical Center, Des Moines, Iowa, 50309, United States; Recruiting Stephen C. Elliott, DO, PhD, FAAP 515-241-6000 elliotsc@ihs.org
Kansas Wesley Medical Center, Wichita, Kansas, 67214, United States; Recruiting David Rosen, MD 316-962-2025
Kentucky Kosair Children's Hospital, Louisville, Kentucky, 40202-3830, United States; Recruiting Salvatore J. Bertolone, MD 502-852-8450
Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington, Kentucky, 40536-0284, United States; Recruiting Martha F. Greenwood, MD 859-323-6771 mfgree0@pop.uky.edu
Louisiana Children's Hospital of New Orleans, New Orleans, Louisiana, 70118, United States; Recruiting Lolie Chua Yu, MD 504-896-9740
MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, 70112, United States; Recruiting Jill Gilbert, MD 504-568-5613 jgilbe@lsuhsc.edu
Ochsner Cancer Institute at Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States; Recruiting Marquis Zimri Hodes, MD, PhD 504-842-5230
Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana, 70112, United States; Recruiting Marshall A. Schorin, MD 504-988-5412 mschori@tulane.edu
Maine CancerCare of Maine at Eastern Maine Medial Center, Bangor, Maine, 04401, United States; Recruiting Judith B. Allen, MD 207-973-7520
Maine Children's Cancer Program, Scarborough, Maine, 04074-9308, United States; Recruiting Craig A. Hurwitz, MD 207-885-7565 hurwic@mmc.org
Maryland Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, 21225, United States; Recruiting Joseph Michael Wiley, MD 410-601-5864 jwiley@lifebridehealth.org
Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, 21201-1595, United States; Recruiting Neil Jeffrey Grossman, MD 410-328-2808 ngrossma@peds.umaryland.edu
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, 21231-2410, United States; Recruiting Cindy Schwartz, MD 410-955-7385 schwac@ijhmi.edu
Walter Reed Army Medical Center, Silver Spring, Maryland, 20910, United States; Recruiting Kip R. Hartman, MD 301-319-9116
Massachusetts Baystate Regional Cancer Program at D'Amour Center for Cancer Care, Springfield, Massachusetts, 01107, United States; Recruiting David A. Steele, MD 413-794-9338 david.steele@bhs.org
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, 02115, United States; Recruiting Holcombe Edwin Grier, MD 617-632-3971 holcombe-grier@dfci.harvard.edu
Floating Hospital for Children, Boston, Massachusetts, 02111, United States; Recruiting Cynthia S. Kretschmar, MD 617-636-5535 ckretschmar@tufts-nemc.org
UMASS Memorial Cancer Center - University Campus, Worcester, Massachusetts, 01655, United States; Recruiting Ghazala Naheed Usmani, MD 508-856-4225 usmanin@ummhc.org
Michigan Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, 48910, United States; Recruiting Renuka Gera, MD 517-334-2337
Bronson Methodist Hospital, Kalamazoo, Michigan, 49007-5364, United States; Recruiting
Leonard August Mattano, MD, PhD 616-341-6350
CCOP - Beaumont, Royal Oak, Michigan, 48073-6769, United States; Recruiting Jeanne Archer, PhD, APN 248-551-8299 carcher@beaumon.edu
Children's Hospital of Michigan, Detroit, Michigan, 48201, United States; Recruiting Yaddanapudi Ravindranath, MBBS 313-745-5649 ravi@med.wayne.edu
DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States; Recruiting David Robert Freyer, DO 616-391-2086
Hurley Medical Center, Flint, Michigan, 48503, United States; Recruiting Susumu Inoue, MD 810-762-7303 sinoue1@hurleymc.com
Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, 48202, United States; Recruiting Hassan M. Yaish, MD 313-916-3138
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109-0914, United States; Recruiting Raymond J. Hutchinson, MD 734-936-8785
Van Elslander Cancer Center at St. John Hospital and Medical Center, Detroit, Michigan, 48236, United States; Recruiting Hadi Sawaf, MD 313-647-3200 hadi.sawaf@stjohn.org
William Beaumont Hospital - Royal Oak, Royal Oak, Michigan, 48073-6769, United States; Recruiting Charles A. Main, MD 248-551-0360
Minnesota Children's Hospitals and Clinics - Minneapolis/St. Paul, Minneapolis, Minnesota, 55404, United States; Recruiting Maura C. O'Leary, MD 612-813-5940
Mayo Clinic Cancer Center, Rochester, Minnesota, 55905, United States; Recruiting Carola A.S. Arndt, MD 507-284-2695 carndt@mayo.edu
St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota, 55805, United States; Recruiting Jacquelyn Dawn Wiermaa, MD 218-786-3625
Mississippi
University of Mississippi Medical Center, Jackson, Mississippi, 39216-4505, United States; Recruiting Dale Jeanette Pullen, MD 601-984-5220
Missouri Cardinal Glennon Children's Hospital, Saint Louis, Missouri, 63104, United States; Recruiting William Shay Ferguson, MD 314-577-5638
Children's Mercy Hospital, Kansas City, Missouri, 64108, United States; Recruiting Maxine L. Hetherington, MD 816-234-3265
St. Louis Children's Hospital, Saint Louis, Missouri, 63110, United States; Recruiting Robert James Hayashi, MD 314-454-4118 hayashi_r@kids.wustl.edu
University of Missouri - Columbia, Columbia, Missouri, 65203, United States; Recruiting Barbara Anne Gruner, MD 573-882-3961 grunerb@health.missousri.edu
Nebraska Children's Hospital of Omaha, Omaha, Nebraska, 68114, United States; Recruiting Minnie Abromowitch, MD 402-955-3949 mabromo@unmc.edu
UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha, Nebraska, 68198-2168, United States; Recruiting Peter F. Coccia, MD 402-559-7257 pcoccia@unmc.edu
Nevada Sunrise Hospital and Medical Center, Las Vegas, Nevada, 89109, United States; Recruiting
Jonathan Bernstein, MD 702-732-0971 jonbern1@aol.com
New Hampshire Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, 03756, United States; Recruiting Eric Christian Larsen, MD 603-650-5541 eric.c.larsen@hitchcock.org
New Jersey Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, 07601, United States; Recruiting Michael B. Harris, MD 201-996-5437 mbharris@humed.com
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, 08903, United States; Recruiting Richard A. Drachtman, MD 732-235-5437 drachtri@umdnj.edu
Newark Beth Israel Medical Center, Newark, New Jersey, 07112-2094, United
States; Recruiting Peri Kamalakar, MD 973-926-7161 pkamalak@sghcs.com
St. Joseph's Hospital and Medical Center, Paterson, New Jersey, 07503, United States; Recruiting Mary Ann Bonilla, MD 973-754-3230 bonillam@sjhmc.org
Valerie Fund Children's Center at Atlantic Health, Summit, New Jersey, 07901, United States; Recruiting Hazem Helmy Mahmoud, MD 973-971-6731
New Mexico University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico, 87131, United States; Recruiting Jami Frost, MD 505-272-4461
New York Albert Einstein Cancer Center at Albert Einstein College of Medicine, Bronx, New York, 10461, United States; Recruiting Eva Radel, MD 718-920-7844
Brookdale University Hospital and Medical Center, Brooklyn, New York, 11212, United States; Recruiting Kusum Viswanathan, MD 718-240-5904
Brooklyn Hospital Center, Brooklyn, New York, 11201-5493, United States; Recruiting Swayamprabha Sadanandan, MD 718-250-6074 sws9001@nyp.org
Cancer Center of Albany Medical Center, Albany, New York, 12208, United States; Recruiting Jennifer M. Pearce, MD 518-262-5513 pearcej@mail.amc.edu
Comprehensive Cancer Center at Maimonides Medical Center, Brooklyn, New York, 11219, United States; Recruiting Ludovico Guarini, MD 718-283-8173 lguarini@maimonidesmed.org
Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New York, 10032, United States; Recruiting Linda Granowetter, MD 212-305-8652 lg519@columbia.edu
James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York, 14642, United States; Recruiting Barbara Lawrence Asselin, MD 716-275-2981
Long Island Cancer Center at Stony Brook University Hospital, Stony Brook, New York, 11794, United States; Recruiting
Robert Ingalls Parker, DSc 631-444-4000
Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United States; Recruiting Peter G. Steinherz, MD 212-639-7951
Mount Sinai School of Medicine, New York, New York, 10029, United States; Recruiting Elizabeth Raetz, MD 212-241-7022
New York Medical College, Valhalla, New York, 10595, United States; Recruiting M. Fevzi Ozkaynak, MD 914-493-7997 mehmet_ozkaynak@nymc.edu
New York Weill Cornell Cancer Center at Cornell University, New York, New York, 10021, United States; Recruiting Patricia J.V. Giardina, MD 212-746-3400
Schneider Children's Hospital, New Hyde Park, New York, 11042, United States; Recruiting Arlene Sara Redner, MD 718-470-3460
SUNY Downstate Medical Center, Brooklyn, New York, 11203, United States; Recruiting Sreedhar P. Rao, MD 718-270-1693
SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, United States; Recruiting Ronald L. Dubowy, MD 315-464-5294 dubowyr@upstate.edu
North Carolina Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, 28232-2861, United States; Recruiting Daniel P. McMahon, MD 704-355-1130 dmcmahon@carolinas.org
Comprehensive Cancer Center at Wake Forest University, Winston Salem, North Carolina, 27157-1081, United States; Recruiting Thomas Williams McLean, MD 336-716-4324
Duke Comprehensive Cancer Center, Durham, North Carolina, 27710, United States; Recruiting Philip Paul Breitfeld, MD 919-684-3377
Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, North Carolina, 27858-4354, United States; Recruiting Charles W. Daeschner, MD 252-744-4676 DaeschnerC@mail.ecu.edu
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, 27599, United States; Recruiting
Stuart Gold, MD 919-966-0985 stubaby@med.unc.med
Mission Hospitals, Asheville, North Carolina, 28801, United States; Recruiting Orren Beaty, DO, PhD 823-213-5770 orren.beaty@msj.org
Presbyterian Cancer Center at Presbyterian Hospital, Charlotte, North Carolina, 28233, United States; Recruiting Mark Mogul, MD 704-384-1900
North Dakota Dakota Cancer Institute at Innovis Health - Dakota Clinic, Fargo, North Dakota, 58103-4940, United States; Recruiting Janet K. Tillisch, MD 701-364-4964
Ohio Children's Hospital Medical Center of Akron, Akron, Ohio, 44308-1062, United States; Recruiting Steven J. Kuerbitz, MD 330-543-8730 skuerbitz@chmca.org
Children's Medical Center - Dayton, Dayton, Ohio, 45404, United States; Recruiting Emmett H. Broxson, MD, FAAP 937-641-3111 broxsone@childrensdayton.org
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229-3039, United States; Recruiting John Peter Perentesis, MD 513-636-6090
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, 44195, United States; Recruiting Karen A. Bringelsen, MD 216-444-7923
Columbus Children's Hospital, Columbus, Ohio, 43205-2696, United States; Recruiting Amanda Termuhlen, MD 614-722-3552
Forum Health-Tod Childrens Hospital, Youngstown, Ohio, 44501, United States; Recruiting Ayman Saleh, MD, FAAP 330-884-3955 asaleh@neoucom.edu
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, 44106-5065, United States; Recruiting Susan Wiersma, MD 216-844-3345 srw3@po.cwru.edu
St. Vincent Mercy Medical Center, Toledo, Ohio, 43608, United States; Recruiting Rama Jasty, MD 419-251-8215 rjasty@mco.edu
Toledo Children's Hospital, Toledo, Ohio, 43601, United States; Recruiting Richard M. Shore, MD 419-471-5437
Oklahoma CCOP - Oklahoma, Tulsa, Oklahoma, 74136, United States; Recruiting James B. Lockhart, MD 918-491-5878
Children's Hospital at Oklahoma University Medical Center, Oklahoma City, Oklahoma, 73104, United States; Recruiting William H. Meyer, MD 405-271-5311 william-meyer@ouhsc.edu
Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa, Oklahoma, 74136, United States; Recruiting Martina Christine Hum, MD 918-494-2525 pedonc@saintfrancis.com
Oregon CCOP - Columbia River Oncology Program, Portland, Oregon, 97225, United States; Recruiting Keith S. Lanier, MD 503-216-6260
Doernbecher Children's Hospital at Oregon Health & Science University, Portland, Oregon, 97239-3098, United States; Recruiting H. Stacy Nicholson, MD, MPH 503-494-1543
Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon, 97227, United States; Recruiting Janice Faye Olson, MD 503-413-2200
Pennsylvania Children's Hospital at Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033, United States; Recruiting John E. Neely, MD 717-531-6012 jen6@psu.edu
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States; Recruiting Richard Berry Womer, MD 215-590-2229 rwomer@mail.med.upenn.edu
Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States; Recruiting Arthur Kim Ritchey, MD 412-692-5055 kim.ritchey@chp.edu
Geisinger Medical Center, Danville, Pennsylvania, 17822-1320, United States; Recruiting Jeffrey Taylor, MD 570-271-6848
St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, 19134-1095, United States; Recruiting Gregory E. Halligan, MD 215-427-5000 Gregory.Halligan@tenethealth.com
Rhode Island Rhode Island Hospital, Providence, Rhode Island, 02903, United States; Recruiting Sam W. Lew, MD 401-444-5171
South Carolina Children's Hospital of Greenville Hospital System, Greenville, South Carolina, 29605, United States; Recruiting Cary Ernest Stroud, MD 864-455-8898
Hollings Cancer Center at Medical University of South Carolina, Charleston, South Carolina, 29425-0721, United States; Recruiting Julio C. Barredo, MD 843-792-2957 barredjc@musc.edu
Palmetto Health South Carolina Cancer Center, Columbia, South Carolina, 29203, United States; Recruiting Ronnie W. Neuberg, MD 803-434-3533 ronnie.neuberg@palmettohealth.org
South Dakota Avera Cancer Institute, Sioux Falls, South Dakota, 57105-1080, United States; Recruiting Marwan D. Hanna, MD 605-322-7595
Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, South Dakota, 57117-5039, United States; Recruiting Jakica Tancabelic, MD 605-333-7171 jtancabe@usd.edu
Tennessee East Tennessee Children's Hospital, Knoxville, Tennessee, 37901, United States; Recruiting Ray C. Pais, MD 865-541-8266 hemonc@etch.com
East Tennessee State University Cancer Center at Johnson City Medical Center, Johnson City, Tennessee, 37614-0622, United States; Recruiting David K. Kalwinsky, MD 423-433-6200 sjcrhta@msha,cin
St. Jude Children's Research Hospital, Memphis, Tennessee, 38105-2794, United States; Recruiting Wayne Lee Furman, MD 901-495-3300
Vanderbilt Children's Hospital, Nashville, Tennessee, 37232-6310, United States; Recruiting James A. Whitlock, MD 615-936-1762
Texas Baylor College of Medicine, Houston, Texas, 77030, United States; Recruiting C. Philip Steuber, MD 713-798-6970
CCOP - Scott and White Hospital, Temple, Texas, 76508, United States; Recruiting Lucas Wong, MD 254-724-1053 lwong@swmail.sw.org
Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas, 76508, United States; Recruiting Dick Suh, MD, PhD 254-724-9852 DSuh@swmail.sw.org
Children's Hospital of Austin, Austin, Texas, 78701, United States; Recruiting Sharon K. Lockhart, MD 512-324-8480 slockhart@stcaustin.com
Cook Children's Medical Center - Fort Worth, Fort Worth, Texas, 76104, United States; Recruiting Timothy C. Griffin, MD 682-885-4020 TGriffin@cookchildrens.org
Covenant Children's Hospital, Lubbock, Texas, 79410, United States; Recruiting John Iacuone, MD 806-725-4840
MBCCOP - South Texas Pediatrics, San Antonio, Texas, 78229-3900, United States; Recruiting Anne-Marie Langevin, MD 210-704-3405 langevin@uthscsa.edu
MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4009, United States; Recruiting Joann Ater, MD 713-792-6665 jater@mdanderson.org
Medical City Dallas Hospital, Dallas, Texas, 75230, United States; Recruiting Carl Lenarsky, MD 972-566-6647 carl.lenarsky@usoncology.com
Methodist Cancer Center at Methodist Specialty and Transplant Hospital, San Antonio, Texas, 78229-3902, United States; Recruiting Jaime Estrada, MD 210-575-8130
San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air Force Base, Texas, 78236, United States; Recruiting Aaron Pitney, MD 210-292-5684
Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas, 75390-9063, United States; Recruiting Naomi J. Winick, MD 214-648-3074 naomi.winick@utsouthwestern.edu
Texas Tech University Health Sciences Center School of Medicine, Amarillo, Texas, 79106, United States; Recruiting Curtis Wade Turner, MD 806-354-5434 curtis.turner@ttuhsc.edu
University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78207, United States; Recruiting
Paul Jan Thomas, MD 210-704-3405 thomasp@uthscsa.edu
University of Texas Medical Branch, Galveston, Texas, 77555-0209, United States; Recruiting Frederick Szujuei Huang, MD 409-772-2341 fshuang@utmb.edu
Utah Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah, 84112, United States; Recruiting Carol S. Bruggers, MD 801-585-0303
Vermont Vermont Cancer Center at University of Vermont, Burlington, Vermont, 05401-3498, United States; Recruiting Alan C. Homans, MD 802-847-2850
Virginia Cancer Center at the University of Virginia, Charlottesville, Virginia, 22908, United States; Recruiting Kimberly Dunsmore, MD 434-924-9333
Carilion Medical Center for Children at Roanoke Community Hospital, Roanoke, Virginia, 24029, United States; Recruiting Joan Mistretta Fisher, MD, PhD 540-985-8055 jmfisher@carilion.com
Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United States; Recruiting Rebecca L. Byrd, MD 757-668-7243 byrdrl@chkd.org
INOVA Fairfax Hospital, Falls Church, Virginia, 22042-3300, United States; Recruiting Jay N. Greenberg, MD 703-698-1110
Massey Cancer Center at Virginia Commonwealth University, Richmond, Virginia, 23298-0121, United States; Recruiting Nancy L. Dunn, MD 804-828-9605 nldunn@hsc.vcu.edu
Naval Medical Center, Portsmouth, Portsmouth, Virginia, 23708-5100, United States; Recruiting Paulette Charese Bryant, MD 804-398-5767
Washington Children's Hospital and Regional Medical Center - Seattle, Seattle, Washington, 98105, United States; Recruiting Douglas Hawkins, MD 206-987-3096
Deaconess Medical Center, Spokane, Washington, 99210-0248, United States; Recruiting
Steven K. Bergstrom, MD 509-473-7012 bergst@empirehealth.org
Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109-1024, United States; Recruiting Jean E. Sanders, MD 206-667-4348 jsanders@fhcrc.org
Group Health Central Hospital, Seattle, Washington, 98112, United States; Recruiting Philip Herzog, MD 425-883-5291
Madigan Army Medical Center, Tacoma, Washington, 98431-0001, United States; Recruiting Kelly Faucette, MD 253-968-1305 kelly.faucette@nw.amedd.army.mil
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington, 98415-0299, United States; Recruiting William J. Thomas, MD 253-403-4915 hemonc@multicare.org
West Virginia Cabell Huntington Hospital, Huntington, West Virginia, 25701, United States; Recruiting Andrew Pendleton, MD 304-691-1384 dpendlet@marshall.edu
Mary Babb Randolph Cancer Center at West Virginia University Hospitals, Morgantown, West Virginia, 26506-9300, United States; Recruiting Frank G. Keller, MD 304-293-1217
West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division, Charleston, West Virginia, 25302, United States; Recruiting Elizabeth M. Kurczynski, MD 304-388-1540 ekurczynski@hsc.wvu.edu
Wisconsin Bellin Memorial Hospital, Green Bay, Wisconsin, 54301, United States; Recruiting Dorothy J. Ganick, MD 920-433-6025
CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin, 54449, United States; Recruiting Tarit Kumar Banerjee, MD, FACP 715-387-5511
CCOP - St. Vincent Hospital Cancer Center, Green Bay, Green Bay, Wisconsin, 54301, United States; Recruiting Thomas J. Saphner, MD 920-432-5134
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse, Wisconsin, 54601, United States; Recruiting Robert S. Ettinger, MD 608-782-7300 rsetting@gundluth.org
Marshfield Clinic - Marshfield Center, Marshfield, Wisconsin, 54449-5772, United
States; Recruiting Harlan James Nickerson, MD 715-387-5018
Midwest Children's Cancer Center, Milwaukee, Wisconsin, 53226, United States; Recruiting Bruce M. Camitta, MD 414-456-4106
St. Vincent Hospital, Green Bay, Wisconsin, 54307-9070, United States; Recruiting Jon Brandt, MD 920-433-8670
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, 53792-6164, United States; Recruiting Diane Puccetti, MD 608-263-0320
Australia, New South Wales Children's Hospital at Westmead, Westmead, New South Wales, 2145, Australia; Recruiting Geoffrey McCowage, MD 61-2-9845-2122
Sydney Children's Hospital, Randwick, New South Wales, 2031, Australia; Recruiting Glenn Marshall, MD, MBBS 61-2-9382-1721 g.marshall@unsw.edu.au
Australia, Queensland Royal Children's Hospital, Brisbane, Queensland, 4029, Australia; Recruiting Liane Lockwood, MBBS, FRACP 617-363-61356 liane_lockwood@health.gld.gov.au
Australia, South Australia Women's and Children's Hospital, North Adelaide, South Australia, 5006, Australia; Recruiting Maria Louis Kirby, MBBS, FRACP 61-8-8161-7411 kirbym@mail.wch.sa.gov.au
Australia, Victoria Royal Children's Hospital, Parkville, Victoria, 3052, Australia; Recruiting David Ashley, MBBS, FRACP, PhD 61-39-345-5522
Australia, Western Australia Princess Margaret Hospital for Children, Perth, Western Australia, 6001, Australia; Recruiting David L. Baker, MD, MBBS, FRACP, FRCPA 61-8-9340-8234
Canada, Alberta Alberta Children's Hospital, Calgary, Alberta, T2T 5C7, Canada; Recruiting Douglas R. Strother, MD 403-943-7272
Cross Cancer Institute, Edmonton, Alberta, T6G 1Z2, Canada; Recruiting Paul Edward Grundy, MD 780-432-8894 pgrundy@cha.ab.ca
Canada, British Columbia British Columbia Children's Hospital, Vancouver, British Columbia, V6H 3V4, Canada; Recruiting Paul C.J. Rogers, MB, ChB, FRCPC, MBA, FRCP 604-875-2322 progers@cw.bc.ca
Canada, Manitoba CancerCare Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada; Recruiting Rochelle A. Yanofsky, MD 204-787-4163 rochelle.yanofsky@cancercare.mb.ca
Canada, Newfoundland and Labrador Janeway Children's Health and Rehabilitation Centre, St. John's, Newfoundland and Labrador, A1B 3V6, Canada; Recruiting John (Jack) Hand, MD 709-777-4799 hcc.hanjg@hccsj.nf.ca
Canada, Nova Scotia IWK Health Centre, Halifax, Nova Scotia, B3J 3G9, Canada; Recruiting Dorothy R. Barnard, MD 902-470-8291 dorothy.barnard@iwk.nshealth.ca
Canada, Ontario Children's Hospital of Eastern Ontario, Ottawa, Ontario, K1H 8L1, Canada; Recruiting Jacqueline Halton, MD 613-737-7600 ext. 2370
Children's Hospital of Western Ontario, London, Ontario, N6C 2V5, Canada; Recruiting Anne Elizabeth Lois Cairney, MD 519-685-8494 beth.cairney@lhsc.on.ca
Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada; Recruiting Alberto S. Pappo, MD 416-813-6594 alberto.pappo@sickkids.ca
McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario, L8N 3Z5, Canada; Recruiting Ronald D. Barr, MD 905-521-2100 ext. 73464 rbarr@mcmaster.ca
Canada, Quebec Centre de Recherche du Centre Hospitalier de l'Universite Laval, Sainte-Foy, Quebec, GIV 4G2, Canada; Recruiting Yvan Samson, MD 418-656-4141
Hopital Sainte Justine, Montreal, Quebec, H3T 1C5, Canada; Recruiting Albert Moghrabi, MD 514-345-4969 albert.moghrabi@umontreal.ca
Montreal Children's Hospital at McGill University Health Center, Montreal, Quebec, H3G 1A4, Canada; Recruiting Carolyn R. Freeman, MB, BS, FRCPC 514-412-8040 carolyn.freeman@muhc.mcgill.ca
Canada, Saskatchewan
Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan, S4T 7T1, Canada; Recruiting Christina Ten Suan Goh, MD 306-766-2205 tgoh@scf.sk.ca
Saskatoon Cancer Centre, Saskatoon, Saskatchewan, S7N 4H4, Canada; Recruiting Ali S. Kaiser, MD 306-655-2684
Netherlands University Medical Center Groningen, Groningen, 9700 RB, Netherlands; Recruiting Willem A. Kamps, MD, PhD 31-50-361-4213 w.a.kamps@bkk.azg.nl
New Zealand Starship Children's Health, Auckland, New Zealand; Recruiting Lochie Teague, MD 64-9-307-4949 ext. 6295 lochiet@adhb.govt.nz
Puerto Rico Puerto Rico Cancer Center at University of Puerto Rico - Medical Sciences Campus, San Juan, 00936-5067, Puerto Rico; Recruiting Nilka J. Barrios, MD 787-756-3230
San Jorge Children's Hospital, Santurce, 00912, Puerto Rico; Recruiting Luis Antonio Clavell, MD 787-726-0316 luis.clavell@paviahealth.com
Switzerland Swiss Pediatric Oncology Group Bern, Bern, CH 3010, Switzerland; Recruiting Annette Ridolfi-Luethy, MD 41-31-632-9372
Swiss Pediatric Oncology Group Geneva, Geneva, CH 1211, Switzerland; Recruiting Pierre Wacker, MD 41-22-382-3311
Swiss Pediatric Oncology Group Lausanne, Lausanne, CH 1011, Switzerland; Recruiting Maja Beck Popovic, MD 41-21-314-3567
Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute Myeloid Leukemia, or Myeloproliferative Disorder.RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill cancer cells. Sometimes the transplanted cells can make an immune response against the body's normal tissues. Methotrexate and cyclosporine may prevent this from happening.
PURPOSE: Phase I/II trial to study the effectiveness of donor peripheral stem cell transplantation in treating patients who have acute myeloid leukemia, or myeloproliferative disorder. Fred Hutchinson Cancer Research Center, Seattle, Washington, 98104, United
States; Recruiting Ann Woolfrey, MD 206-667-4453
XK469R in Treating Patients With Refractory Hematologic Cancer.RATIONALE: Drugs used in chemotherapy, such XK469R, work in different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of XK469R in treating patients who have refractory hematologic cancer.
Illinois University of Chicago Cancer Research Center, Chicago, Illinois, 60637-1470, United States; Recruiting Wendy Stock, MD 773-834-8982
Texas MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United States; Recruiting Francis J. Giles, MD 713-792-8217 fgiles@mdanderson.org