Post on 21-Feb-2018
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DEFINICION Asthma is a chronic infammatory
disorder o the airways in which many cells and cellularelements play a role: in particular, mast
cells, eosinophils, T lymphocytes, macrophages, neutrophils,and epithelial cells. In susceptible
individuals, this infammation causes recurrent episodes owheezing, breathlessness, chest
tightness, and coughing, particularly at night or in the earlymorning. These episodes are
usually associated with widespread but variable airfowobstruction that is oten reversible either
spontaneously or with treatment. The infammation alsocauses an associated increase in the
existing bronchial hyperresponsiveness to a variety o stimuli.eversibility o airfow limitation
may be incomplete in some patients with asthma (EPR 1991;
EPR 2 1997
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FISIOPATOLOGIA Y
PATOGENESIS
BRONCOCONSTRICCION: Contraccin delmsculo liso en respuesta a estimulos alrgicos oirritantes.
EDEMA: infamacin ms progresiva y persistentehipersecrecin moco , tapones, hipertroa ehiperplasia msculo liso.
HIPERREACTIVIDAD VIA AEREA : Respuestaexagerada roncoconstrictora a una variedad de
estimulos. REMODELAMIENTO:Camios estructurales
permanentes .
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DIAGNOSTICO
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HALLAZGOS FISICOS
!"#$R"%&'()*C"+% +R*-
&"")*%C"* C+% R$"R*C"+% %+R/*) ,
(+R0*1*
&$CR$C"+% %*&*), $1$/*, #+)"#+&
$C0$/* ,1$R/*""&
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ESPIROMETRIA
+&R'CC"+% *) ()'2+ *$R$+
3R*1+ 1$ +&R'CC"+%
R$4$R&"")"1*1 #+& 5
%+ C+R$)*C"+% #R$C"&* C+% &"%+/*&
$& %+R/*) %+ $-C)'6$ *&/* 6 &" $&+&R'C"4+ 6 R$4$R&")$ %+ $& 13 "$%$ 7'$*&+C"*R&$ $) #*R+% 1$ &"%+/*& 6 $-C)'"R +R+&13 #*R* 13 *&/*
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