Post on 15-Feb-2020
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BSD SELF ASSESSMENT SESSION 2018
Dr Arti Bakshi,
Consultant
Dermatopathologist,
Royal Liverpool
University Hospital.
CASE 11
43/F, 2 year history of well defined papular
keratotic rash, initially appeared on ankles and
lower legs and then spread to thighs, arms and
neck.
Keratosis pilaris
Hyperkeratois lenticularis perstans (Flegel’s
disease)
Lichenoid drug eruption
Hyperkeratosis follicularis et parafollicularis in
cutem penetrans (Kyrle’s disease)
DIAGNOSIS??
Keratosis pilaris
Hyperkeratosis lenticularis perstans (Flegel’s
disease)
Lichenoid drug eruption
Hyperkeratosis follicularis et parafollicularis in
cutem penetrans (Kyrle’s disease)
Keratosis pilaris c/o
Weedon textbook Kyrle’s disease c/o
dermpedia
Lichenoid drug eruption Flegel’s disease c/o dermnet
Keratosis pilaris
Hyperkeratosis lenticularis perstans (Flegel’s
disease)
Lichenoid drug eruption
Hyperkeratosis follicularis et parafollicularis in
cutem penetrans (Kyrle’s disease)
FLEGEL’S DISEASE
Large numbers, small, discrete, grey-brown/red-brown, circular papules with a well-developed scale
Dorsum of foot, lower legs, upper arms, pinnae, buttocks, trunk, dorsal aspects of hands, palms & soles
Removal of the scale associated with pinpoint bleeding
c/o dermnet
Characterised by protracted clinical course (years
to decades)
Most cases sporadic, some evidence of AD
inheritance in a subset of cases
Unknown aetiology
HISTOLOGY
Another
differential of
a lichenoid
inflammatory
reaction
The clue is in
the keratin!!
CASE 11: FLEGEL’S DISEASE
Acknowledgements:
Dr Tapati Sinha, Consultant Dermatologist
Dr Jessica White, ST5 Histopathology
THANK YOU.