Carisolv PREZENTACIJA

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8/4/2019 Carisolv PREZENTACIJA

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Dental caries areDental caries arebacterial induced necrosis of tooth structurebacterial induced necrosis of tooth structure

Treatment should focus on the removal of necrotic tissue with a bacteriocidal approach.

Carisolv ® a product from ORASOLV AB

Cases and product info

“Since the invention and application of rotary instruments, the operative treatment

of carious lesions has often resulted in considerable removal of tooth structure.” Banerjee A, Watson TF, Kidd EA. Br Dent J. 2000 May 13;188(9):476-82

Minimally invasive dentistry focuses on preservingMinimally invasive dentistry focuses on preservinghealthy and sound tissue.healthy and sound tissue.

The art of intervention lies in NOT removing more thanThe art of intervention lies in NOT removing more than

necessary.necessary.

“ “ In modern dentistry the primary aim when excavatingIn modern dentistry the primary aim when excavating

carious dentin is to eradicate only the highly infected,carious dentin is to eradicate only the highly infected,irreversiblyirreversibly demineralizeddemineralized and denatured biomassand denatured biomass …” …”

Banerjee A, Watson TE, Kidd EA. Dent Update 2000 Jul-Aug;27(6):272-6

In a study aimed to evaluate the efficiency (time taken) andIn a study aimed to evaluate the efficiency (time taken) andeffectiveness (quantity of dentine removed) of carious dentineeffectiveness (quantity of dentine removed) of carious dentineexcavationexcavation ……

……bur excavation was quickest butbur excavation was quickest but overpreparedoverprepared cavitiescavities ……

……CarisolvCarisolv ®® excavation was slower butexcavation was slower but removed adequateremoved adequate

quantities of tissuequantities of tissue ……

Banerjee A, Kidd EA, W atson TF. Caries Res 2000 Mar-Apr;34(2):144-50

Dec 2005:Dec 2005:

62 abstract in62 abstract in PubMedPubMed respondingrespondingto search w ordto search w ord “ “ CarisolvCarisolv ” ” !!

I f search termI f search term “ “ chemomechanicalchemomechanical ” ” also included,also included,

PubMedPubMed lists 91 abstracts !lists 91 abstracts !

TheThe CarisolvCarisolv method w asmethod w asintroduced on the market in 1997 !introduced on the market in 1997 !

TheThe CarisolvCarisolv ®® method wasmethod wasintroduced on the market in 1997 !introduced on the market in 1997 !

Carisolv ® is the best studiedmethod for caries removal

Carisolv ® removes necrotic, decayed, dentine andleaves healthy tooth structure unaffected –

- a minimal invasive approach when biology is animportant issue.

A r v i d s o n A ., e t a l . Biomaterials 2002 Oct;23(19):3977-83Ba n er j e e A ., et a l . Caries Res 2000;34(2):144-150Han n in g M. Clin Oral Investig 1999;3(3):155-9Sa k o o l n a m a r k a R., e t a l. Aust Dent J 2002 Jun;47(2):116-22

W e n n e r b e r g A . , e t a l . Eur J Oral Sci 1999;107(4):297-306Ya z i ci A R. , e t a l . Oper Dent 2002 Jul-Aug;27(4):360-6

Carisolv ® has NO effect on sound and healthydentin.

Carisolv ® leaves a rougher dentin surface suitablefor modern restauration techniques.

H aa k R., et a l. Eur J Oral Sci 2000;108(5):449-455

H o so y a Y., e t a l . J Dent 2001 May;29(3):163-171

Kubo S. , e t a l . Oper Dent 2002 Jul-Aug;27(4):387-95Carisolv ® a product from ORASOLV AB

Cariso lv Car iso lv ® d o e s n o t e l ici t d o e s n o t e l i ci t

a d v e r se ef f e ct o n t o p u l p a d v e r se ef f e ct o n t o p u l p t i s s u e .t i s s u e .

B r a u n A . , e t a l .B r a u n A . , e t a l . QuintessenzQuintessenz 2000;51(5):4612000;51(5):461 -- 469469D a m m a s c h k e D a m m a s c h k e T., e t a l .T., e t a l . J Dent 2001;29(4):283J Dent 2001;29(4):283 -- 290290D a m m a s c h k e D a m m a s c h k e T., e t a l T., e t a l J Dent 2002 Jan;30(1):59J Dent 2002 Jan;30(1):59 -- 6565Youn g C. , e t a l .Youn g C. , e t a l . J Dent 2001;29(4):275J Dent 2001;29(4):275 -- 281281

Cl i n i ca l an d h i s t o l o g i ca l st u d y o n o r a l m u c o sa Cl i n i ca l an d h i s t o l o g i ca l st u d y o n o r a l m u c o sa a f t e r p r o l o n g e d ex p o su r e t o a f t e r p r o lo n g e d ex p o su r e t o Car iso lv Car iso lv ® d i d n o t d i d n o t

sh o w an y i n f l am m at o r y r eact i on s .sh o w an y i n f l am m at o r y r eact i on s .

A r v i d s s o n A r v i d s s o n A . , e t a l .A . , e t a l . GerodontologyGerodontology 2001 Dec;18(2):1092001 Dec;18(2):109 -- 1313

C d d i f

Cariso lv Car iso lv ® sa f e l y a n d s el e ct i v e l y r e m o v e s A LLsa f e l y a n d se l ect i v e l y r e m o v e s A LL

t h e d e ca y ed d e n t i n e t h e d e ca y ed d e n t i n e – – l e av i n g a ca r i e s f r e e l e av i n g a ca r i e s f r e e a n d cl e an su r f a ce .a n d cl e an su r f a ce .

B a n e r j e e B a n e r j e e A . , e t a l .A . , e t a l . J Dent 2000;28(3):179J Dent 2000;28(3):179 -- 186186Er i cson D. , e t a l .Er i cson D. , e t a l . Caries Res 1999;33(3):171Caries Res 1999;33(3):171 -- 7777Fure Fure S. , e t a l .S. , e t a l . Caries Res 2000;34(3):275Caries Res 2000;34(3):275 -- 280280M a r a g a k i s M a r a g a k i s GM. , e t a l .GM. , e t a l . Caries Res 2001;35(3):205Caries Res 2001;35(3):205 -- 210210M u n s h i M u n s h i AK. , e t a l .AK., e t a l . JJ ClinClin PediatrPediatr Dent 2001;26(1):49Dent 2001;26(1):49 -- 5454

N a d a n o v s k y N a d a n o v s k y P., e t a l .P., e t a l . Caries Res 2001;35(3):384Caries Res 2001;35(3):384 -- 389389Sp l i e th Sp l i e th C. , e t a l .C. , e t a l . ClinClin OralOral InvestigInvestig 2001 Dec;5(4):2502001 Dec;5(4):250 -- 253253

C d d t i f

Car iso lv Car i so lv ® – – t h e N t h e N o o 1 ch o i ce w h e n b i o lo g y i s i m p o r t a n t ! 1 ch o i ce w h e n b i o lo g y i s i m p o r t a n t !

Method Soundenamel

Sounddentine

Cariousenamel

Cariousdentine

Handexcavators

– – + ++

Rotary burs +++ +++ +++ +++

Air-abrasion +++ +++ ++ +

CarisolvCarisolv ® –– –– –– ++++++Lasers + + + +

Baner jee A., et al. British Dental Journal 2000;188(9):476-482 .

Methods for restorative dental treatments

Intact collagenIntact collagen

Mineralized dentineMineralized dentineDemineralizedDemineralized carious dentinecarious dentine

Denatured collagenDenatured collagen

How does it work – mode of action ?

DE 2001DE 2001

CarisolvCarisolv ®® applicationapplication

DE 2001DE 2001

MechanicalMechanicalremoval of removal of decay.decay.

CarisolvCarisolv ®® hashas “ “ disconnecteddisconnected ” ” necrotic dentinenecrotic dentine

How does it work – mode of action ?p

DE 2001DE 2001

AfterAfter CarisolvCarisolv ®® applicationapplicationand after etching.and after etching.

The surface is now readyThe surface is now readyfor restoration.for restoration.

Use instrument of your own choiceUse instrument of your own choice ……

… just add Carisolv ® for clean, safeand appropriate caries removal

1.1. 2.2. 3.3. 4.4. 5.5.

Carisolv ®

• When healthy tooth structures are precious…• When biology is important…

• When quality counts…

• When you care about your patients…

Contact info:Contact info:

www.orasolv.sewww.orasolv.seinfo@orasolv.seinfo@orasolv.se

+46 (0)31 74 11 780+46 (0)31 74 11 780

+46 (0)31 74 11 781+46 (0)31 74 11 781

2) Cover the cavity with gel and wait for 30 seconds until thecarious tissue has been softened.

3) Softened caries can then be scraped away

1) Drilling, when the cavity needs to be opened up, for adjustmentof cavity periphery and when there are large amounts of cariesand the risk to affect healthy tissue is minimal.

4) Repeat without waiting 30 seconds, until the cavity is free of caries.

5) When repeating make sure cavity always well moisten withCarisolv ®

3) When cariesfree – inspection and filling as usual

Take advantage of the chemistry:Take advantage of the chemistry:

•• Check if cavity caries free !Check if cavity caries free !–– before fillingbefore filling–– before crown cementationbefore crown cementation–– when close to the pulpwhen close to the pulp

•• Less bleeding !Less bleeding !•• Less pain !Less pain !•• Less noise !Less noise !

Root surfaces

Time for excavation:

Carisolv ® and rotatinginstruments – equal

Carisolv ® less traumatic

Before cementation of permanent crownBefore cementation of permanent crown -- and bridgeworkand bridgework ……

……useuse CarisolvCarisolv ® ® to check if surface caries free !to check if surface caries free !

CarisolvCarisolv ® ®

–– in difficult caries situationsin difficult caries situations ……

CarisolvCarisolv ® ® –– inin

difficult cariesdifficult cariessituationssituations ……

CarisolvCarisolv ® ® –– in difficult caries situationsin difficult caries situations ……

Normal dentineNormal dentineCases and product info

Necrotic dentineNecrotic dentine

Translucent dentineTranslucent dentine

Reparative dentineReparative dentine

Dental pulp chamberDental pulp chamber

Amino acidsAmino acidsCases and product info

CHCH22

CHCH 22 CHCH 22HH33

NHNH 33

COOCOO--

CHCH33

CHCH 33

COOCOO--

CHCH 22

LeucineLeucine

LysineLysineHH

NHNH 33

COOCOO --

CHCH 22 CHCH 22

GlutamicGlutamic acidacid

Carisolv ™ gelCases and product info

Singlemix

Multimix

Selection of instruments.Selection of instruments.

Start with MultiStart with Multi -- Star if possible.Star if possible.

CarisolvCarisolv ® ® instrumentsinstrumentsare nare n onon -- invasiveinvasive ……

Drills andDrills and excavatorsexcavators areareintendedintended to beto be invasiveinvasive ……

In vitro researchIn vitro researchCases and product info

Caries removalCaries removalEricson et al 1998Ericson et al 1998BanerjeeBanerjee et al 2000et al 2000CederlundCederlund et al 1999et al 1999

SpliethSplieth et al 1999et al 1999DammaschkeDammaschke et al 2000et al 2000HaffnerHaffner et al 2000et al 2000Moran et al 2000Moran et al 2000NeutschilNeutschil et al 2000et al 2000Tonami et al 1999Tonami et al 1999FluckigerFluckiger et al 2005et al 2005

Dentine bondingDentine bondingHaakHaak et al 2000et al 2000FrankenbergerFrankenberger et al 2000et al 2000Harada et al 2000Harada et al 2000PawlowskaPawlowska et al 2000et al 2000

SudaSuda et al 2000et al 2000CehreliCehreli et al 2003et al 2003Burrow et al 2003Burrow et al 2003SonodaSonoda et al 2005et al 2005

No adverse effects dentineNo adverse effects dentineBanerjeeBanerjee et al 2000et al 2000CederlundCederlund et al 1999et al 1999HannigHannig et al 1999et al 1999WennerbergWennerberg et al 1999et al 1999

Pulp effectsPulp effectsDammaschkeDammaschke et al 2001et al 2001Young et al 2001Young et al 2001

Hybrid layer effectsHybrid layer effectsMason et al 1999Mason et al 1999PerdigaoPerdigao et al 1999et al 1999SudaSuda et al 1999et al 1999Collagen effectsCollagen effects

HannigHannig et al 1999et al 1999JepsenJepsen et al 1999et al 1999Tonami et al 1999Tonami et al 1999DammaschkeDammaschke et al 1999bet al 1999b

Surface structureBanerjee et al 2000Haffner et al 2000Tonami et al 1999Arvidsson et al2002,2004 Carisolv ® a product from ORASOLV AB

Clinical researchClinical researchCases and product info

Caries removalCaries removalEricson et al 1999Ericson et al 1999FureFure et al 2000,2004et al 2000,2004BerakdarBerakdar et al 2000et al 2000Burke et al 1999Burke et al 1999

CarneiroCarneiro et al 2000et al 2000HaffnerHaffner et al 1999et al 1999MasourasMasouras et al 1999et al 1999MaragakisMaragakis et al 2000et al 2000

SongpaisanSongpaisan et al 2002et al 2002KakabouraKakaboura et al 2003et al 2003KavvadiaKavvadia et al 2004et al 2004Bergmann,Bergmann, LeitaoLeitao 20052005

Restoration survivalRestoration survivalFureFure et al 2000, 2004et al 2000, 2004NevrinNevrin et al 1999et al 1999Zimmerman et al 2000Zimmerman et al 2000

No adverse effectsNo adverse effectsFureFure et al 2000et al 2000NevrinNevrin , Carlen 1999, Carlen 1999Zimmerman et al 2000Zimmerman et al 2000WennerbergWennerberg et al 2001et al 2001

Pulp effectsPulp effectsLumbauLumbau et al 2000et al 2000Braun et al 2000Braun et al 2000DammaschkeDammaschke et al 2001et al 2001BulutBulut et al 2004et al 2004

Antibacterial effectsAntibacterial effectsKneistKneist et al 1999et al 1999BaysanBaysan et al 1999et al 1999Lager et al 2003Lager et al 2003

AzrakAzrak et al 2004et al 2004

Review articlesReview articlesCases and product info

ReviewsReviewsBanerjeeBanerjee et al 2000et al 2000BeeleyBeeley et al 2000et al 2000MaragakisMaragakis et al 2001et al 2001Morrow et al 2000Morrow et al 2000

ZiskindZiskind et al 2005et al 2005

Carisolv PREZENTACIJA

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