DoernbecherPediatric Hematology/Oncology

Fellowship Program

2008

History

• Current 3-yr program ACGME-approved in 1997– Established by Len Johnson and Gary Jones

• First fellow entered program in July 2000

• Kiwanis Clubs of OR and SW WA support 2 positions yearly, + growing an endowment– Grass roots fund raising

• Other funding: GME, DCH, NRSA, St Baldricks

• 2 first year and 6 total fellows now each year

Applicants

• NRMP since 2001• ERAS starting 2009

• For 2 entry positions July 2009: – 42 applicants– 14 interviewed

• 4-yr Adolescent & Young Adult fellowship – for entry 7-09– combined medical oncology + PHO

Residency Training Programsof our PHO Fellows

PHO Fellowship Programs – National Data

For starting date 7-08:

150 applicants 129 positions

54 programs (1 – 6 positions/yr)

from 119 applicants for 7/05

15 PHO Faculty

H.S. Nicholson L Stork L Wolff D Tilford G Thomas

T Lamkin S MalempatiB ChangP KurreE Nemecek

R TrueworthyM RechtK Nazemi R ButlerS Lindemulder

PHO Clinical and Research Programs

• Leukemia & Lymphoma– Linda Stork; Bill Chang

• Neuro-Oncology– Kelly Nazemi; Kathy Perko, RN, PNP; Stacy Nicholson

• Solid Tumors– Suman Malempati; Thomas Lamkin

• Stem Cell Transplant– Eneida Nemecek; Peter Kurre – Tara Berhardt, RN, PNP; Amy Kenagy, RN, PNP

• Hemophilia & Non-Malignant Blood Disorders– Michael Recht; Greg Thomas

• Palliative Care– Greg Thomas; Kathy Perko, RN, PNP

PHO Programs (con’t)

• Investigational Therapeutics– Suman Malempati; Linda Stork

• Survivorship– Susan Lindemulder; Larry Wolff; Kelly Anderson,

RN, FNP

• Adolescent & Young Adult– Susan Lindemulder; Kelly Anderson, RN, FNP

• Neuropsychology– Robert Butler, PhD

• Bone Marrow Failure– Peter Kurre

• Lab-based Research– Peter Kurre; Bill Chang

Some of our 2007 Team

Jan Naas: Fellowship coordinator

Purpose - To Train Fellows to:

– Deliver exceptional patient care• Treat children • Support families

– Engage in scholarship and research• Treat, cure, and prevent

– Cancers and blood disorders• Improve the quality of a child’s long life

– Teach • Students, residents, fellows, RNs• Colleagues• Patients and families

Training Program

• First year– Clinical rotations, continuity clinics– Week day night and weekend call– One month: Research Development

• Choose lab mentor before 2nd year

• Second and Third Years– 80% research: translational lab-based or

clinical, or MPH– Human Investigation Program x 2 years– Continuity clinic ½ day each week– Week day night and weekend call

Learn From Patients

Dr. Suman Malempati

Learn From Clinical Mentors and Other Fellows

Learn in the Lab

Dr. Veronica Flood

Learn From Other Subspecialists

Fellows’ Research Projects and Mentors

• Grover Bagby, MD – Fanconi genes and cancer

• Sri Nagalla, MD, PhD – Gaba receptors in neuroblastoma

• Rosalie Sears, PhD – C-Myc stabilization• Dave Farrell, PhD – Dysfibrinogenemia• Mather Thayer,PhD – Chromosone instability• Rosalie Sears, PhD – C-Myc in brain tumors• Scott Howard, MD (St Jude’s) – Hodgkin’s

lymphoma RX in developing countries• Michael Deininger, MD, PhD – Tyrosine

kinase inhibitors in CML

Fellows’ Research Projects and Mentors

• Sri Nagalla, MD, PhD – genomics and proteomics of neuroblastoma

• Dan Marks, MD, PhD – Glucose Tolerance in ALL survivors

• James Huang, MD – In Vitro Drug Sensitivity of ALL blasts

• Eneida Nemecek, MD – BMT toxicities in AYAs

• Michael Deininger, MD, PhD – Leukemia inhibitors

• Grover Bagby, MD – Fanconi proteins and informatics

Where have they gone after training?

100% PHO Boards passing rate

10 graduates as of July 2008

What motivates our fellows to work so hard?

Kids like these