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CURRICULUM VITAE
Joy Lincoln, PhD, FAHA
PRESENT TITLE AND AFFILIATION
Principal Investigator
Center for Cardiovascular Research
The Heart Center
The Research Institute at Nationwide Children’s Hospital, Columbus, Ohio
Associate Director of Faculty Development
Nationwide Children’s Hospital, Columbus, Ohio
Tenured Associate Professor
Department of Pediatrics
The Ohio State University College of Medicine
Columbus, Ohio
CITIZENSHIP AND VISA STATUS
US Citizen
OFFICE ADDRESS
Center for Cardiovascular Research
Research Building III, WB4239
575 Children’s Crossroads
Columbus, Ohio, 43215
P: (614) 355-5752
F: (614) 355-5725
joy.lincoln@nationwidechildrens.org
EDUCATION
UNDERGRADUATE EDUCATION
1995-1998 University of Durham, United Kingdom
BSc, Biomedical Sciences
POST-GRADUATE EDUCATION & TRAINING
1998-2002 University of Durham, United Kingdom
PhD, Molecular and Developmental Biology
Mentor: Dr. Nicholas Hole, PhD
1999 University of Durham, United Kingdom
Teaching Certificate in Higher Education
2002-2006 Cincinnati Children’s Hospital Medical Center
Division of Molecular Cardiovascular Biology
Post Doctoral Research Fellow
Mentor: Dr. Katherine E. Yutzey
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ACADEMIC APPOINTMENTS
2006-2011 Assistant Professor (Tenure Track)
Department of Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, Florida
2011-Present Associate Professor (Tenure Track),
Department of Pediatrics
The Ohio State University College of Medicine
Principal Investigator,
Center for Cardiovascular Research
Nationwide Children’s Hospital Research Institute
SERVICE
ACADEMIC ADMINISTRATIVE RESPONSIBILITIES
2010-2011 Director
Postdoctoral Programs Office
University of Miami, Leonard M. Miller School of Medicine
2015-Present Associate Director
Center for Faculty Development
Nationwide Children’s Hospital
INSTITUTIONAL/LOCAL ACTIVITIES
2006-2011 Member
Graduate Faculty, Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine
2007-2011 Member
Graduate Faculty, Molecular Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine
2006-2011 Member
Postdoctoral Steering Committee
University of Miami, Leonard M. Miller School of Medicine
2006 Member
Department of Molecular and Cellular Pharmacology Faculty Search Committee
University of Miami, Leonard M. Miller School of Medicine
2007-2010 Chair and Host
Cardiovascular Research Symposium
University of Miami, Leonard M. Miller School of Medicine
2008-2011 Member
Transgenic Animal Facility Committee
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University of Miami, Leonard M. Miller School of Medicine
2008-2010 Member
Program in Biomedical Sciences Admission Steering Committee
University of Miami, Leonard M. Miller School of Medicine
2008-2011 Member
Faculty Council in Animal Resources Committee
University of Miami, Leonard M. Miller School of Medicine
2010 Chair
Department of Molecular and Cellular Pharmacology Faculty Chair Search
Committee
University of Miami, Leonard M. Miller School of Medicine
2011-Present Member
Graduate Faculty, Biomedical Sciences Graduate Program
The Ohio State University College of Medicine
2011-Present Member
Graduate Faculty, Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine
2013-Present Member
Rodent Use Advisory Committee
Nationwide Children’s Hospital Research Institute
2013-Present Member
Faculty Development Office Steering Committee
Nationwide Children’s Hospital Research Institute
2012, 2013 Co-host
Midwest Heart Valve Meeting
The Heart Center at Nationwide Children’s Hospital
2014-Present Member
Faculty Forum Organizing Committee
Nationwide Children’s Hospital Research Institute
2014-Present Member
Summer Student Education Committee
Nationwide Children’s Hospital Research Institute
2015-Present Scholarship Oversight Committee
Critical Care Medical Fellows
Nationwide Children’s Hospital
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2015-Present Junior Faculty Awards Committee
Department of Pediatrics
Nationwide Children’s Hospital
2015-Present Director,
American Heart Association Summer Undergraduate Research Fellowship
Program
Nationwide Children’s Hospital
2016-Present Co-organizer
DiscoveryX; Tedx-like event
Nationwide Children’s Hospital
2016-Present Scholarship Oversight Committee
Cardiology Medical Fellows
Nationwide Children’s Hospital
2016 Member
Graduate Faculty, Bioengineering Graduate Program
The Ohio State University, College of Engineering
2016-2017 Member
Search Committee; Chief Scientific Officer
Nationwide Children’s Hospital
2017-Present Member
Women in the Department of Pediatrics
Nationwide Children’s Hospital
2017-Present Member
Center for Cardiovascular Research Search Committee
Nationwide Children’s Hospital
2017 Member
Research Retreat Organizing Committee
Nationwide Children’s Hospital
2017 Member
Clinical and Translational Intramural Funding Committee
Nationwide Children’s Hospital
2017 Member
The Heart Center Research Resource Committee
Nationwide Children’s Hospital
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2017-2018 Member
Search Committee; Chief of Cardiology
Nationwide Children’s Hospital
REGIONAL ACTIVITIES
2013-Present Member
Central Ohio American Heart Association Steering Committee at Nationwide
Children’s Hospital
American Heart Association Central Ohio Chapter
NATIONAL ACTIVITIES
2007-2010 Member
Scientific Review Board, Basic Cell and Molecular Biology
American Heart Association National Region
2009 Ad-hoc Member
Scientific Review Board, Cardiac Differentiation and Development,
National Institute of Health (National Heart, Lung and Blood Institute)
2011-Present Member
Scientific Review Board,
Cardiovascular Development III, American Heart Association National Region
2013 External Board Member
Micah Bachelor Award for Excellence in Children’s Health Research,
University of Miami, Leonard M. Miller School of Medicine
2013-2016 Member
Scientific Advisory Board
Cardiovascular Research, W. W. Smith Charitable Trust
2014-Present Member
Weinstein Cardiovascular Development Meeting International Committee
2014 Member
Scientific Review Board, Innovative Grant Research Awards, American Heart
Association National Region
2014-Present Nominated Member
International Weinstein Cardiovascular Development Meeting
2015-2017 Member
Scientific Review Board, Physiology and Pathobiology of Cardiovascular and
Respiratory Systems (ZRG1 F10A, fellowships)
National Institute of Health (National Heart, Lung and Blood Institute)
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2015-Present Nominated Member
International Society of Applied Cardiovascular Biology
2016-Present Chair
Women’s Leadership Committee
International Society of Applied Cardiovascular Biology
2016-Present Member
The Heart Valve Society
2016-2017 Adhoc Member
Scientific Review Board, Cardiovascular Contractility and Heart Failure (CCHF)
National Institute of Health (National Heart, Lung and Blood Institute)
2017 Nominated Co-Host
Weinstein Cardiovascular Development Meeting, Columbus 2017
2017 Adhoc Member
Scientific Review Board, National Institute of Health, Special Emphasis Panel
Systems Developmental Biology for Understanding Embryonic Development and
the Ontogeny of Structural Birth Defects
2018-2022 Permanent Member (from Fall 2018)
Scientific Review Board, Cardiovascular Development and Differentiation (CDD)
National Institute of Health (National Heart, Lung and Blood Institute)
2018 Adhoc Member
Scientific Review Board, National Institute of Health, Development I (DEVI)
2018 Adhoc Member
Scientific Review Board, National Institute of Health, Special Emphasis Panel
Biophysical and Biomechanical Aspects of Embryonic Development
2018 Adhoc Member
Scientific Review Board, National Institute of Health, Mentored Clinical and
Basic Science
HONORS AND AWARDS
2004 American Heart Association Postdoctoral Fellowship
Great Rivers Affiliate, American Heart Association
2005 Travel Award and Honorable Mention
Weinstein Cardiovascular Development Meeting, Tucson, AZ, USA
2006 Travel Award for Scientific Excellence
American Association of Anatomists Meeting at EB, San Francisco, CA, USA
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2006 Winner Presely Zeiss Postdoctoral Fellow Award
American Association of Anatomists Meeting at EB, San Francisco, CA, USA
2006 Travel Award and Honorable Mention
Weinstein Cardiovascular Development Meeting, St. Petersburg, FL, USA
2007 Florida Cardiovascular Researcher of the Year
Florida Heart Research Institute
2011 Invited Moderator “Valvuloseptal Development and Congenital Malformations”
Weinstein Cardiovascular Development Meeting, Cincinnati, OH, USA
2012 Invited Moderator “Valve Development”
Weinstein Cardiovascular Development Meeting, Chicago, IL, USA
2012, 2013 Co-Host Midwest Heart Valve Day
The Research Institute at Nationwide Children’s, Columbus, OH, USA
2014-Present Team Captain Nationwide Children’s Hospital
American Heart Association “Heart Walk Central Ohio”
2014 Appointed Co-Host
Weinstein Cardiovascular Development Meeting 2017 in Columbus, OH, USA
2014 Invited Moderator “Emerging role of cardiac fibroblasts”
American Heart Association Scientific Sessions, Chicago, IL, USA
2014 Participant American Heart Association “Life is Why” branding platform
2014 “Outstanding Principal Investigator in Basic Science for 2014”
Nationwide Children’s Hospital, Columbus, OH, USA
2015 Invited Moderator “Endocardium and cardiac valves”
Weinstein Cardiovascular Development Meeting, Boston, MA, USA
2016 Invited Moderator “Heart valve biology”
Weinstein Cardiovascular Development Meeting, Durham, NC, USA
2016 Elected Fellow of the American Heart Association
Arteriosclerosis, Thrombosis and Vascular Biology Council
2016-Present Chair
Women’s Leadership Committee
International Society of Applied Cardiovascular Biology
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RESEARCH SUPPORT
ONGOING RESEARCH
1R01HL135031 Martinez (PI) 01/03/2017-01/02/2022
National Institute of Health, National Heart, Lung and Blood Institute
“The role of Rbfox2 in hypoplastic left heart syndrome”
This proposal will examine the requirement and mechanisms of Rbfox2 in the onset of
hypoplastic left heart syndrome”
Role: Co-I
Total direct and indirect costs: $2,333,937
17UFEL33420025 Lincoln (PI) 02/01/2017-01/31/2020
American Heart Association Summer Undergraduate Research Fellowship
Nationwide Children’s Hospital Summer Undergraduate Research Program
This award provides stipends for five undergraduate students to perform cardiovascular-related
research at Nationwide Children’s Hospital Research Institute during the summer
Role: PI
Total direct and indirect costs: $60,000
1R01HL132801 Lincoln, Garg, Lilly (MPI) 07/01/2016-06/30/2020
National Institute of Health, National Heart, Lung and Blood Institute
The role of Notch in Calcific Aortic Valve Disease
This proposal will focus on determining the mechanisms of Notch activity in heart valve
interstitial cells in the setting of aortic valve calcification
1R01HL117946-01 Lincoln (PI) 04/01/2015-3/31/2019
National Institute of Health, National Heart, Lung and Blood Institute
The role of Sox9 in calcific aortic valve disease
This proposal will focus on examining the molecular regulation of Sox9 in Calcific Aortic Valve
Disease
Role: PI
Total direct and indirect costs: $1,868,750
1R01HL121797-01 Garg (PI) 04/01/2015-3/31/2019
National Institute of Health, National Heart, Lung and Blood Institute
Molecular mechanisms of aortic valve formation
This proposal will focus on examining the role of Notch signaling during valve formation in the
developing embryo.
Role: Co-I
Total direct and indirect costs: $1,868,750
Role: Co-PI, Contact PI
Total direct and indirect costs: $2,635,845
PENDING SUPPORT
1R01HL142685 Lincoln (PI) 07/01/2018-06/30/2023
National Institute of Health, National Heart, Lung and Blood Institute
Medical Therapies in the Treatment of Calcific Aortic Valve Disease
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This proposal will focus on examining the molecular mechanisms underlying pharmacological
treatment of Calcific Aortic Valve Disease using a protein export inhibitor drug
Impact Score 33
1R01HL144004 Grande-Allen, Liu, Lincoln (MPI) 07/01/2018-06/30/2023
National Institute of Health, National Heart, Lung and Blood Institute
Regulation of valve calcification via genetic modulation of glycosaminoglycan (GAG) fine
structure
This proposal will examine the potential of modifying specified GAG structure to modulate
valve calcification in aging valves in vitro and in vivo.
COMPLETED RESEARCH
1R13HL136103 Lincoln, Garg (PI) 09/01/2016-08/30/2017
National Institute of Health, National Heart, Lung and Blood Institute
“Weinstein Cardiovascular Development Conference”
This award will provide funds to support the 2017 Weinstein Cardiovascular Development
Conference hosted by Drs. Lincoln and Garg in Columbus, OH.
Total direct and indirect costs: $21,000
15UFEL22760002 Lincoln (PI) 02/01/2015-01/31/2017
American Heart Association Summer Undergraduate Research Fellowship
Nationwide Children’s Summer Undergraduate Research Program
This award provides stipends for five undergraduate students to perform cardiovascular-related
research at Nationwide Children’s Hospital Research Institute during the summer
Role: PI
Total direct and indirect costs: $40,000
14GRNT19630003 Lincoln (PI) 07/01/2014-06/30/2016
American Heart Association Grant-In-Aid
The role of Sox9 in calcific aortic valve disease
This study will examine the mechanisms of Sox9 function in calcific aortic valve disease.
Role: PI
Total direct and indirect costs: $154,000
1R01HL091878 Lincoln (PI) 08/01/2008-07/31/2013
National Institute of Health, National Heart, Lung and Blood Institute
Molecular regulation of heart valve development and function
This award was focused on examining FGF-ERK signaling and in vivo function of Scleraxis
during heart valve formation.
Role: PI
0735220N Lincoln (PI) 07/01/2007-07/31/2011
American Heart Association Science Development Award
Molecular and cellular regulation of heart valve cell lineage diversification and differentiation.
This award examined the role of BMP and FGF signaling in diversification of heart valve
precursors cells during embryonic development.
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Role: PI
*Terminated 07/31/2008 due to scientific overlap
1R01HL091878 Lincoln (PI) 08/01/2009-07/31/2011
National Institute of Health, National Heart, Lung and Blood Institute
ARRA Administration Supplement
1R01HL091878 Lincoln (PI) 12/01/2010-11/30/2011
National Institute of Health, National Heart, Lung and Blood Institute
Diversity Administration Supplement
07KN-07 Lincoln (PI) 07/01/2007-06/30/2010
Florida Biomedical Research Program, James and Esther King
Molecular regulation of heart valve development and disease
This award examined Sox9 function in connective tissue homeostasis in embryonic and adult
heart valves.
Role: PI
PUBLICATIONS
ARTICLES IN PEER REVIEWED JOURNALS
1. Armstrong, L., Lako, M., Lincoln, J., Cairns, P.M., Hole, N. mTert expression correlates
with telomerase activity during the differentiation of murine embryonic stem cells. Mechanisms
of Development 97, 109-116, 2000.
2. Lako, M., Lindsay, S., Lincoln, J., Cairns, P.M., Armstrong, L., Hole, N.
Characterisation of Wnt gene expression during the differentiation of murine embryonic stem
cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. Mechanisms of
Development 103, 49-59 2001.
3. Lincoln J., Alfieri, C.M., Yutzey, K.E. Development of heart valve leaflets and
supporting apparatus in chicken and mouse embryos. Developmental Dynamics 229 (4), 2004.
Front cover article.
4. Lincoln J., Alfieri, C.M., Yutzey, K.E. BMP and FGF regulatory pathways control
cartilage- and tendon-like cell lineage differentiation of heart valve precursor cells.
Developmental Biology 292;290-302, 2006.
5. Lincoln J., Lange, A.L., Yutzey, K.E. “Hearts and Bones”: Shared regulatory
mechanisms in heart valve, cartilage, tendon and bone. Review article. Developmental Biology
294;292-302, 2006.
6. Hinton Jr., R.B*., Lincoln, J*., Deutsch, G., Osinska, H., Benson, W., Yutzey, K.E.
Extracellular matrix remodeling and organization in developing and diseased aortic valves.
Circulation Research 98(11):1431-8, 2006. *Both authors contributed equally. Front cover
article.
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7. Lincoln J., Florer, J.B., Deutsch, G.H., Wenstrup, R.J., Yutzey, K.E. ColVa1 and
ColXIa1 are required myocardial morphogenesis and heart valve development. Developmental
Dynamics, 235(12);3295-3305, 2006.
8. Lincoln J., Kist, R., Scherer, G. Yutzey, K.E. Sox9 is required for valve precursor cell
expansion and extracellular matrix organization during mouse heart valve development.
Developmental Biology 305(1):120-32, 2007.
9. Levay, A.K., Peacock, J.D., Lu Y., Hinton Jr., Koch, M., R.B., Kadler, K.E., Lincoln, J.
Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during
murine heart valve formation in vivo. Circulation Research 103(9): 948-56, 2008.
10. Peacock, J.D., Lu, Y., Kadler, K.E., and Lincoln, J. Temporal and Spatial expression of
collagens during murine atrioventricular heart valve development and maintenance.
Developmental Dynamics (237)10;3051-8, 2008.
11. Peacock, J.D., Levay, A.K., Gillaspie, D.B., Tao, G., Lincoln, J. Reduced Sox9 function
promotes heart valve calcification phenotypes in vivo. Circulation Research 106(4):712-9, 2010.
12. Ricci, M. Mohapatra, B., Urbiztondo, A., Birusingh, R.J., Morgado, M., Rodriguez,
M.M., Lincoln, J., Vatta, M. Upregulation of TFG-/BMP signaling pathway in the Right
Ventricular Myocardium of Newborns with Hypoplastic Left Heart Syndrome. Journal of
Cardiac Failure 16(8):628-34, 2010.
13. Ricci, M., Panos, A.L., Lincoln, J., Salerno, T.A. and Warshauer, L. Is aviation a good
model to study human errors in health care? American Journal of Surgery, 203(6):798-801,
2012.
14. Ge Tao, Agata K. Levay, Thomas Gridley and Joy Lincoln. Mmp15 is a direct target of
Snai1 during endothelial to mesenchymal transformation and endocardial cushion development.
Developmental Biology, 359(2):209-21, 2011.
15. Faul C*, Amaral AP*, Oskouei B*, Hu MC, Sloan A, Isakova T, Gutiérrez OM,
Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ,
Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St. John Sutton M, Ojo A,
Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW,
Kuro-o M, Kusek JW, Keane MG, Wolf M. Fibroblast Growth Factor 23 Induces Left
Ventricular Hypertrophy. Journal of Clinical Investigation, 121(11):4393-408, 2011.
16. Peacock, J.D., Huk, D.J., Ediriweera, H., Lincoln, J. Sox9 transcriptionally represses
Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes. PLoS ONE,
6(10):e26769, Epub 2011.
17. Marco Ricci, MD, Yanji Xu, PhD, Harriet L. Hammond, MS, David A. Willoughby,
PhD, Lubov Nathanson, PhD, Maria M. Rodriguez, MD, Matteo Vatta, PhD, Steven E.
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Lipshultz, MD and Joy Lincoln, PhD. Myocardial alternative RNA splicing and gene expression
profiling in early stage hypoplastic left heart syndrome. PLoS ONE, 7(1);e29784 Epub 2012.
18. Lloye M. Dillon, Sion L. Williams, Aline Hida, Jacqueline D. Peacock, Tomas A. Prolla,
Joy Lincoln and Carlos T. Moraes. Increased Mitochondrial Biogenesis in Muscle Improves
Aging Phenotypes in the mtDNA Mutator Mouse. Human Molecular Genetics 21(10):2288-97,
2012.
19. Ge Tao, PhD, Agata K. Levay, MS, Jacqueline D. Peacock, PhD, Nicole H. Purcell, PhD,
Jose R. Pinto, PhD, Maarten L. Galantowicz, BS, Manuel Koch, PhD, Pamela A. Lucchesi, PhD,
David E. Birk, PhD and Joy Lincoln, PhD. Collagen XIV is important for growth and structural
integrity of the myocardium. Journal of Molecular and Cellular Cardiology, 53(5):626-38,
2012.
20. Danielle J. Huk, Harriet L. Hammond, Hiroyuki Kegechika and Joy Lincoln. Increased
dietary intake of vitamin A promotes aortic valve calcification in vivo. Arteriosclerosis,
Thrombosis, and Vascular Biology, 33(2):285-93, 2013
21. Kevin Bosse PhD, Chetan P. Hans PhD, Ning Zhao MS, Sara N. Koenig BA, Nianyuan
Huang BS, Anuradha Guggilam PhD, Stephanie LaHaye, Ge Tao PhD, Pamela A. Lucchesi
PhD, Joy Lincoln PhD, Brenda Lilly PhD and Vidu Garg MD. Endothelial nitric oxide signaling
regulates Notch1 in aortic valve disease. Journal of Molecular and Cellular Cardiology, 60:27-
35, 2013.
22. Ge Tao, Lindsey J. Miller and Joy Lincoln. Snai1 is important for avian epicardial cell
transformation and motility. Developmental Dynamics, 242(6):699-708, 2013.
23. Damien N. Barnette, BS, Alexia Hulin, PhD, Alain C. Colige, PhD and Joy Lincoln,
PhD. MAPK signaling negatively regulates Scleraxis-mediated proteoglycan expression in heart
valves. Journal of Molecular and Cellular Cardiology, 65:137-46, 2013.
24. Miller, L. and Lincoln, J. Isolation of Murine Heart Valve Endothelial Cells. Journal of
Visualized Experiments. 21;(90), 2014
25. LaHaye, S. Lincoln, J. and Garg, V. Genetics of Valvular Heart Disease. Curr. Cardiol.
Rep 16:487, 2014
26. Damien N. Barnette*, Matthew VandeKopple*, Yonggan Wu, David A. Willoughby and
Joy Lincoln. RNA-seq analysis to identify novel roles of Scleraxis during embryonic mouse
heart valve remodeling. PLoS ONE, 9(7), e101425, 2014
27. Xu Zhang, Danielle J. Huk, Joy Lincoln and Yi Zhao. A Microfluidic Shear Device that
Accommodates Parallel High and Low Stress Zones Within the Same Culturing Chamber.
Biomicrofluidics, 8(5), 2014
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28. Austin, B. F., Yoshimoto, Y., Shukinami, C., Lincoln, J. Sox9- and Scleraxis-Cre lineage
fate mapping in heart valve structures. Journal of Cardiac Development and Disease, 1(2), 163-
176, 2014
29. Marco Ricci, MD, Yongjie Miao, Joy Lincoln, PhD and Mohammad Hassan, MD. Cost-
Benefit Analysis of Robotic versus Non-Robotic Minimally Invasive Mitral Valve Surgery.
Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery: 10(2), 90-95,
2015
30. James I, Yi T, Tara S, Best CA, Stuber AJ, Shah KV, Austin BF, Sugiura T, Lee YU,
Lincoln J, Trask AJ, Shinoka T and Breuer CK. Hemodynamic Characterization of a Mouse
Model for Investigating the Cellular and Molecular Mechanisms of Neotissue Formation in
Tissue Engineered Heart Valves. Tissue Engineering Part C Methods, 2015
31. Tori E. Horne†, Matthew VandeKopple†, Kimberly Sauls, Sara N. Koenig, Lindsey J.
Anstine, Vidu Garg, Russell A. Norris and Joy Lincoln. Dynamic heterogeneity of the heart
valve interstitial cell population in mitral valve health and disease. Journal of Cardiac
Development and Disease, 2, 213-232, 2015 †Both authors contributed equally
32. Hassan M, Miao Y, Maraey A, Lincoln J, Brown S, Windsor J, Ricci M. Minimally
Invasive Aortic Valve Replacement: Cost-Benefit Analysis of Ministernotomy Versus
Minithoracotomy Approach. J Heart Valve Dis. 24(5):531-9, 2015
33. Danielle J Huk, Blair F. Austin, Tori E. Horne, Robert B. Hinton, William C. Ray,
Donald D. Heistad and Joy Lincoln. Valve endothelial cell-derived Tgf1 signaling promotes
nuclear localization of Sox9 in interstitial cells associated with attenuated calcification.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Feb;36(2):328-38
34. Verma SK, Deshmukh V, Nutter CA, Jaworski E, Jin W, Wadhwa L, Abata J, Ricci M,
Lincoln J, Martin JF, Yeo GW, Kuyumcu-Martinez MN. Rbfox2 function in RNA metabolism
is impaired in hypoplastic left heart syndrome patient hearts. Sci Rep. 2016 Aug 3;6:30896.
35. Lindsey J. Anstine, Chris Bobba, Samir Ghadiali and Joy Lincoln. Growth and
maturation lead to altered mRNA profiles and impaired function of heart valve endothelial cells.
Journal of Molecular and Cellular Cardiology. 2016 Nov;100:72-82
36. Frédéric Laurent, Ausra Girdziusaite, Julie Gamart, Iros Barozzi, Javier Lopez-Rios,
Marco Osterwalder, Jennifer A. Akiyama, Joy Lincoln, Axel Visel, Aimée Zuniga and Rolf
Zeller. HAND2 Target Gene Regulatory Networks Control Cardiac Valve Development. Cell
Reports. 2017, 19(8):1602-1613
37. Koenig SN, Lincoln J and Garg V. Genetic Basis of Aortic Valvular Disease Current
Opinions in Cardiology, Feb 2, 2017.
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38. Lindsey J. Anstine, Tori E. Horne, Edwin M. Horwitz and Joy Lincoln. The contribution
of extra-cardiac cells in murine heart valves is age dependent. Journal of American Heart
Association. 2017, 6(10).
39. Alexia Hulin, Lindsey J. Anstine, Andrew J. Kim, Sarah J. Potter, Tony DeFalco, Joy
Lincoln and Katherine E. Yutzey. Macrophage transitions in heart valve development and
myxomatous valve disease. Arteriosclerosis, Thrombosis, and Vascular Biology. Accepted.
INVITED ARTICLES
1. Lincoln, J. and Yutzey, K.E. Molecular and developmental mechanisms of congenital
heart valve disease. Invited review Journal of Birth Defects Research Part A Clin Mol Teratol.
91(6):526-34, 2011.
2. Ricci, M. and Lincoln, J. Molecular markers of cardiomyopathy in cyanotic heart
disease. Progress in Pediatric Cardiology, 32(1):19-23, 2011.
3. Ge Tao, James D. Kotick and Joy Lincoln. Heart Valve Development, Maintenance and
Disease: The Role of Endothelial Cells. Current Topics In Developmental Biology 100:203-32,
2012.
4. Joy Lincoln and Vidu Garg. Etiology of Valvular Heart Disease: Genetic and
Developmental Origins. Circulation Journal, 78(8):1081-7, 2014.
5. Punashi Dutta, PhD and Joy Lincoln, PhD. Calcific Aortic Valve Disease; A
Developmental Biology Perspective. Invited Review, Current Cardiology Reports. In Press.
6. Donika Gallina and Joy Lincoln. Dynamic Expression Patterns of Sox9 in Embryonic,
Post Natal and Adult Heart Valve Structures. Invited Research Article, The Anatomical Record;
Roger Markwald Special Edition. Accepted.
7. Emily Nordquist, Stephanie LaHaye, Casey Nagel and Joy Lincoln.. Comparing
molecular profiles of postnatal and adult murine aortic heart valves using RNA-seq analysis.
Frontiers in Cardiovascular Medicine. Accepted.
EDITORIALS
1. Joy Lincoln. To ‘cell’ and back. Journal of Molecular and Cellular Cardiology, 81:94-
95, 2015. Invited.
2. Joy Lincoln. The cardiac matrix revolution: Post-translational modification of Scleraxis.
Journal of Molecular and Cellular Cardiology, 2016 Mar 8;93:106-107. Invited.
BOOK CHAPTERS
1. Danielle Huk and Joy Lincoln. Oxidative Stress in Cardiovascular Disease: Basic
Research and Clinical Practice. Oxidative Stress in Cardiac Valve Development. Springer
Publication. 2014,
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2. Lindsey J. Anstine and Joy Lincoln. Advances in Heart Valve Biomechanics: The Role
of Mechanics in Valvular Physiology, Mechanobiology, and the Bioengineering of Repair and
Replacement. Molecular and Cellular Developments in Heart Valve Development and Disease.
Springer Publication. 2015
EDITORIALS AND REVIEW ACTIVITIES
JOURNAL REVIEWER
American Heart Journal - 2009
American Journal of Physiology; Heart – 2014, 2016
Anatomical Record, 2018
Annals of Biomedical Engineering – 2013
Atherosclerosis, Thrombosis and Vascular Biology – 2011, 2012, 2014, 2015, 2016, 2017
BBA Molecular Biology of Disease - 2015
Biochimica et Biophysica Acta – 2015
BMC Biology - 2016
Cardiovascular Pathology – 2013
Cells, Tissues, Organs - 2015
Circulation Research – 2009, 2010, 2011, 2013, 2015, 2016, 2017
Comprehensive Physiology - 2014
Developmental Biology – 2006, 2008, 2014, 2016
Developmental Cell - 2016
Developmental Dynamics – 2009, 2011, 2014, 2016
Expert Review of Cardiovascular Therapy – 2014
FASEB – 2009, 2011
Human Molecular Genetics – 2007
Journal of American Heart Association – 2016, 2017
Journal of Cardiovascular Development and Disease – 2014, 2016
Journal of Developmental Biology - 2013
Journal of Molecular and Cellular Cardiology – 2008, 2009, 2012, 2013, 2014, 2015, 2016,
2017, 2018
Journal of Visualized Experiments – 2014
Nature Communications – 2016, 2018
PLoS ONE – 2011, 2012, 2013
Proceedings of the National Academy of Sciences – 2014
Stem Cells - 2008
The International Journal of Biochemistry and Cell Biology – 2009
Trends in Cardiovascular Medicine – 2012
TEACHING
COURSES TAUGHT
1995-1998 Teaching assistant in Biomedical Sciences
150 hours/yr teaching laboratory classes (Undergraduate)
University of Durham, United Kingdom
2006-2011 Course Leader, “Molecular Techniques in Cardiovascular Research”
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9, 1 hour lab techniques classes for PhD students and Post Doctoral Fellows on
the NIH Training Grant
University of Miami, Leonard M. Miller School of Medicine
2006-2011 Co-Leader, “Cardiovascular Journal Club”
Monthly 1 hour class for PhD students and Post Doctoral Fellows on the NIH
Training Grant
University of Miami, Leonard M. Miller School of Medicine
2006-2011 Course Leader, “Pharmacokinetics” small group discussions
1 hour class for 2nd year medical students
University of Miami, Leonard M. Miller School of Medicine
2007-2008 Course Leader, “Journal Club”
5, 90 minute classes for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2007-2011 Lecturer, “Cardiovascular Development”
1, 2 hour lecture for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2008-2009 Lecturer, “Technical Aspects of Transgenesis”
1, 2 hour lecture for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2008-2011 Lecturer, “Embryonic Heart Development”
1, 2 hour lecture for 1st year post graduate students
2, 1 hour paper discussion for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2009-2011 Lecturer, Small Group Teaching “Cell Signaling”
3, 1 hour paper discussion for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2009-2011 Lecturer, “Connective Tissue Biology”
1, 2 hour lecture for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2009-2011 Lecturer, Small Group Teaching “Developmental Biology”
3, 1hour paper discussion for 1st year post graduate students
University of Miami, Leonard M. Miller School of Medicine
2010-2011 Lecturer, “Eukaryotic Model Systems of Human Disease”
2, 1 hour classes including journal discussion
University of Miami, Leonard M. Miller School of Medicine
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2011 Lecturer, “Vascular Endothelial Cells”
1, 1 hour class for 1st year medical students
University of Miami, Leonard M. Miller School of Medicine
2011 Lecturer, “Vascular Smooth Muscle Tone”
1, 1 hour class for 1st year medical students
University of Miami, Leonard M. Miller School of Medicine
2013-2017 Lecturer, “Medical Embryology, The Cardiovascular System”
1, 1 hour class for post graduate anatomy students
The Ohio State University College of Medicine
2014-2017 Lecturer, “Research Programs”
1, 1 hour class for post graduate anatomy students
The Ohio State University College of Medicine
EDUCATION LEADERSHIP ROLES
2010-2011 Director
Postdoctoral Programs Office
University of Miami, Leonard M. Miller School of Medicine
2015-2017 Principal Investigator and Director
American Heart Association Summer Undergraduate Research Fellowship
Program
The Research Institute at Nationwide Children’s Hospital, OH, USA
OTHER EDUCATIONAL PROGRAMS
2011 Lecturer, “Setting Up a Laboratory”
Postdoctoral training program
University of Miami, Leonard M. Miller School of Medicine, FL, USA
2011 Lecturer, “Negotiating a start-up package”
Postdoctoral training program
University of Miami, Leonard M. Miller School of Medicine, FL, USA
2013 Invited panelist, “Career Development opportunities for trainees”
Research Institute Trainee Association Office
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2014 Invited panelist, “Poster Presentations”
Research Institute Trainee Association Office
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2013, 2014 Invited Speaker, “Setting Up a Laboratory”
The Ohio Women’s Chapter
The Ohio State University College of Medicine
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2015, 2106 Invited Speaker, “Science as a Business”
Research Institute Trainee Association Office
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
TEACHING OUTSIDE OF CURRENT INSTITUTION
2012 Invited Seminar, “Setting Up a Laboratory”
Trainee Career Development Program
Cincinnati Children’s Hospital Medical Center, OH, USA
2016 Invited Seminar, “Navigating Fellowship Study Sections”
Trainee Career Development Program
Cincinnati Children’s Hospital Medical Center, OH, USA
LECTURES/PRESENTATIONS
National/International
1. Selected Platform Presentation, “BMP and FGF regulate valve precursor cell
diversification”, Weinstein Cardiovascular Development Meeting, Tucson, AZ, USA, May 2004
2. Selected Platform Presentation, “Sox9 is required for heart valve remodeling”, American
Association of Anatomists Meeting at Experimental Biology, San Francisco, CA, April 2006
3. Invited Speaker, “Molecular mechanisms of heart valve development and disease”,
Department of Biological Sciences, University of Durham, Durham, United Kingdom, March
2006
4. Invited Speaker, “Molecular mechanisms of heart valve development and disease”,
Department of Molecular and Cellular Pharmacology, University of Miami, Leonard M. Miller
School of Medicine, FL, USA, May 2006
5. Invited Speaker, “Molecular Mechanisms of Heart Valve Development”, The Medical
University of South Carolina, Charleston, SC, USA, May 2006
6. Invited Speaker, “The role of Sox9 in heart valve connective tissue homeostasis”, The
“Collagen” Gordon Conference, New London, NH, USA, July 2007
7. Invited Speaker, “Molecular regulation of heart valve development”, Florida
International University, November 2007
8. Selected Platform Presentation, “The role of Scleraxis in heart valve development and
disease”, Weinstein Cardiovascular Development Meeting, Houston, TX, USA, May 2008
9. Invited Speaker, “The role of Scleraxis in heart valve development and disease”, Heart
Valve Biology and Tissue Engineering Conference, London, UK, September 2008
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10. Invited Speaker, “Mechanisms of heart valve development”, Nova Southeastern
University, Fort Lauderdale, FL, USA, January 2009
11. Invited Speaker, “The role of Sox9 and Scleraxis in heart valve remodeling and disease”,
“New insights into cell & tissue interactions in cardiovascular development and disease
workshop” Centro Nacional de Investigaciones Cardiovasculares, Madrid, September 2010
12. Invited Speaker, “Heart valves: Cartilage, tendon and bone”, Department of Biological
Sciences, University of Durham, Durham, United Kingdom, May 2010
13. Invited Speaker, “Molecular mechanisms of heart valve development and disease”, The
Research Institute at Nationwide Children’s Hospital, OH, USA, July 2010
14. Invited Speaker, “Snai1 is required for mmp15 expression during endocardial cushion
formation” “Spring Symposium of the Cardiovascular Developmental Biology Center”, Medical
University of South Carolina, April 2011
15. Invited Speaker, “Molecular mechanisms of adult heart valve disease”, Case Western
Cardiovascular Seminar Series, Cleveland, OH, USA, November 2013
16. Selected Platform Presentation, “Endothelial Tgfβ-mediated nuclear exclusion of Sox9 in
valve interstitial cells promotes calcification”, Weinstein Cardiovascular Development Meeting,
Madrid, Spain, May 2014
17. Invited Speaker, “Endothelial Tgfβ-mediated nuclear exclusion of Sox9 in valve
interstitial cells promotes calcification”, International Society for Heart Research, Miami Beach,
FL, USA, June 2014
18. Invited Speaker, “Heart valve disease; Differential contributions of valve cell
populations”, Department of Internal Medicine, University of Iowa, IA, USA, September 2014
19. Invited Speaker, “Endothelial Tgfβ-mediated nuclear exclusion of Sox9 in valve
interstitial cells promotes calcification”, International SOX meeting, Cleveland, OH, USA,
September 2014
20. Invited Speaker, “Heart valve disease; Differential contributions of valve cell
populations”, Center for Life, University of Newcastle, Newcastle, United Kingdom, March
2015
21. Invited Speaker, “New Insights into Remodeling Mechanisms Involved in Mitral Valve
Prolapse”, Heart Valve Society meeting, Monte Carlo, France, May 2015.
22. Invited Speaker, “Signaling Pathways in Valve Homeostasis and Disease”, Heart Valve
Society meeting, Monte Carlo, France, May 2015
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23. Invited Speaker, “Dynamics of heart valve interstitial cell heterogeneity in health and
disease”, Midwest Valve Day, Charleston, SC, USA, September 2015
24. Invited Speaker, “Exploring dynamics of heart valve endothelial cells”, Human Genetics
Seminar Series, The University of Alabama, Birmingham, Alabama, February 2016
25. Invited Speaker, “Heterogeneity of the Heart Valve Interstitial Cell Population”,
American Heart Association BCVS Scientific Sessions, Phoenix, Arizona, July 2016
26. Invited Speaker, “Developmental insights into valve disease”, International Society for
Applied Cardiovascular Biology, Banff, Alberta, Canada, September 2016
27. Invited Speaker, Aortic Valve Stenosis, Brigham and Women’s Hospital, Boston, MA,
April 2017
28. Invited Speaker, “Targeting nuclear export proteins in the treatment of Calcific Aortic
Valve Disease”, Cardiovascular Research Center Seminar Series, Brigham and Women’s
Hospital, Boston, MA,
29. Invited Speaker, “Targeting nuclear export proteins in the treatment of Calcific Aortic
Valve Disease”, COBRA/Cardiovascular Developmental Biology Center, Medical University of
South Carolina, Charleston, South Carolina, August 2017
30. Invited Speaker, “Targeting nuclear export proteins in the treatment of Calcific Aortic
Valve Disease”, Cardiovascular Center of Excellence Seminar Series, Louisiana State
University, December 2018
31. Invited Speaker and Co-Chair, Heart Valve Society Annual Meeting, New York, March
2018
Local/Regional
1. Invited Speaker, “Stem cells: What do we know?” The Miami Science Museum, Miami,
FL, USA, May 2007
Institutional
1. Invited Speaker, “The “Heart valve” matrix: Revolutions”, Pediatric Grand Rounds,
University of Miami, Leonard M. Miller School of Medicine, FL, USA, November 2008
2. Invited Speaker, “Molecular Mechanisms of heart valve disease”, The Stem Cell
Institute, University of Miami, Leonard M. Miller School of Medicine, FL, USA, September
2009
3. Invited Speaker, “Heart valves: Cartilage and bone”, Department of Cell Biology,
University of Miami, Leonard M. Miller School of Medicine, FL, USA, February 2010
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4. Invited Speaker, “Heart valves: Cartilage and Bone”, Nephrology Grand Rounds,
University of Miami, Leonard M. Miller School of Medicine, FL, USA, August 2011
5. Invited Speaker, “Heart valve development and disease: Cartilage, tendon and Bone”,
Clinical and Translational Seminar Series, The Research Institute at Nationwide Children’s
Hospital, Columbus, OH, USA, April 2012
6. Invited Speaker, “Embryonic origins of adult aortic valve disease” Bench to Outcomes
Seminar Series, Nationwide Children’s Hospital, Columbus, OH, USA, August 2014
7. Invited Speaker, “Utilizing animal models to understand human valve disease
pathogenesis” Clinical and Translational Seminar Series, The Heart Center, Nationwide
Children’s Hospital, Columbus, OH, USA, March 2017
DIRECT SUPERVISION
Junior Faculty
2015-2016 Aaron Trask, PhD
Mentor, K99 recipient
Center for Cardiovascular and Pulmonary Research
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2018-2020 Danielle Gottlieb Sen, MD, MPH
Mentor, Nina Braunwald Award
Assistant Professor of Clinical Surgery, Section of Pediatric Surgery
Children's Hospital New Orleans Pediatric Cardiovascular Surgery
Senior Scientists
2017-Present Karthik Kodigepalli, PhD
Center for Cardiovascular Research & The Heart Center
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
Postdoctoral Fellows
2008-2010 Derek Rosenzweig, PhD
Department of Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2008-2009 Marianna Porto, PhD
Department of Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2009-2010 Brian Ramos, PhD
Department of Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2014-2016 Marie Lockhart, PhD
Center for Cardiovascular and Pulmonary Research
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The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2016-Present Punashi Dutta, PhD
Center for Cardiovascular Research
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2016-Present Donika Gallina, PhD
Center for Cardiovascular Research
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2018-Present Vinal Menon, PhD
Center for Cardiovascular Research
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
Graduate Students
2006-2011 Jacqueline D. Peacock
PhD, Program, Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2008-2012 Ge Tao
PhD, Program, Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010-2014 Damien N. Barnette
PhD, Program, Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2011-2015 Danielle J. Huk
PhD, Program, Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2012-2016 Lindsey J. Anstine (was Miller)
PhD Program, Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2013-2015 Matthew VandeKopple
Master’s Program, Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016-Present Bailey Dye
PhD Program, Biomedical Sciences Graduate Program
The Ohio State University College of Medicine, Columbus, OH, USA
2017-Present Emily Nordquist
PhD Program, Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
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Undergraduate Students
2014-Present Tori Horne
BS. Pre-Med, Biology Major
The Ohio State University College of Medicine, Columbus, OH, USA
2014-2016 Samantha Smith
BS. Pre-Med, Neuroscience Major
The Ohio State University College of Medicine, Columbus, OH, USA
2016-2017 Lauren Haack
BS. Pharmaceutical Sciences
The Ohio State University College of Pharmacy, Columbus, OH, USA
2016-2017 Caleb Colvin
BS. Chemical Engineering
The Ohio State University College of Engineering, Columbus, OH, USA
Summer Students
2013 Sara Both
High School Summer Student Research Scholar
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2014 Maggie Carlos
High School Summer Student Research Scholar
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2015 Emma Cosgrove
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2016 Nadra Suleyman
High School Summer Student Research Scholar
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2016 Maggie Carlos
AHA Summer Undergraduate Research Fellow
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
2017 Andrea Dunlap
AHA Summer Undergraduate Research Fellow
The Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA
Medical Students
2007-2011 James Kotick
M.D. Degree Program
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
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2009 Hasini Ediweera
M.D. Degree Program
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Kenneth Fischler
M.D. Degree Program
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
Student Advisory Committees
2006 Fatima deFraitas
James Potter, PhD, FAHA
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2007-2010 Omar Flores
Kerry Burnstein, PhD
PhD Program in Molecular and Cellular Pharmacology, University of Miami,
Leonard M. Miller School of Medicine, Miami, FL, USA
2008-2013 Sumit Jain
Nanette Bishopric, M.D.
PhD Program in Molecular and Cellular Pharmacology, University of Miami,
Leonard M. Miller School of Medicine, Miami, FL, USA
2009-2011 Ying Wang
Xiang-Xi Xu, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2009-2011 Brittany Ashlock
Enrique Mesri, PhD
M.D./PhD Program in Microbiology and Immunology,
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010-2012 Ansel Amaral
Christian Faul, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010-2013 Michael Kritzer-Cheren
Michael Kapiloff, M.D., PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
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2010-2013 Xi Chen
Matthias Salathe, M.D.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2012-2016 Jeremy Baeten
Brenda Lilly, PhD
Biomedical Sciences Graduate Program
The Ohio State University College of Medicine, Columbus, OH, USA
2013-Present Elizabeth Clark, D.V.M.
Christopher Breuer, M.D.
PhD Program in Veterinary Pathology
The Ohio State University School of Veterinary, Columbus, OH, USA
2013-Present Stephanie LaHaye
Vidu Garg, M.D.
PhD Program in Molecular Genetics
The Ohio State University College of Medicine, Columbus, OH, USA
2013-2016 Jennifer Bosse
Heitham El-Horidi, PhD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2013-Present Timothy Adesanya
Jianjie Ma, PhD
PhD Program in Biomedical Sciences
The Ohio State University College of Medicine, Columbus, OH, USA
2014-2016 Jinmo Gu
Dennis Guttridge, PhD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2015-2016 Sara Koening
Vidu Garg, MD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016-Present Ryan Oba
Prasad Dasi, PhD
PhD Program in Biomedical Engineering
The Ohio State University College of Medicine, Columbus, OH, USA
Qualifying Exam Participation
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2008 Salil Sharma
Nanette Bishopric, M.D.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2009 Ye Jey Lin
Gennaro D’Urso, PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Ben Gerovac
Nevis Fregien, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Wenrui Huang
Danuta Szczesna-Cordary, PhD.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Eric Song
Peter Buchwald, PhD.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Reema Ishtewiwy
Kerry Burnstein, PhD.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2013 Jeremy Baeten
Brenda Lilly, PhD
Biomedical Sciences Graduate Program
The Ohio State University College of Medicine, Columbus, OH, USA
2014 Elizabeth Clark, D.V.M.
Christopher Breuer, M.D.
PhD Program in Veterinary Pathology
The Ohio State University School of Veterinary, Columbus, OH, USA
2014 Stephanie LaHaye
Vidu Garg, M.D.
PhD Program in Molecular Genetics
The Ohio State University College of Medicine, Columbus, OH, USA
2014 Jennifer Bosse
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Heitham El-Horidi, PhD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2014 Rachel Childers
Keith Gooch, PhD
PhD Program in Biomedical Engineering
The Ohio State University School of Engineering, Columbus, OH, USA
2014 Timothy Adesanya
Jianjie Ma, PhD
Biomedical Sciences Graduate Program
The Ohio State University College of Medicine, Columbus, OH, USA
Final Defense Participation
2006 Jacqueline D. Peacock
Joy Lincoln, PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2007 Omar Flores
Kerry Burnstein, PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2008 Ge Tao
Joy Lincoln, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2008 Sumit Jain
Nanette Bishopric, M.D.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2009 Ying Wang
Xiang-Xi Xu, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2009 Brittany Ashlock
Enrique Mesri, PhD
M.D./PhD Program in Microbiology and Immunology,
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2011 Ansel Amaral
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Christian Faul, PhD
PhD Program in Molecular, Cell and Developmental Biology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2013 Michael Kritzer-Cheren
Michael Kapiloff, M.D., PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2013 Chris Rea,
Jiyoung Lee, PhD
Graduate Program in Public Health
The Ohio State University, Columbus, OH, USA
2014 Damien N. Barnette
Joy Lincoln, PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2014 Xi Chen
Matthias Salathe, M.D.
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2015 Danielle J. Huk
Joy Lincoln, PhD
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2015 Rashita Bagchi
Michael Czubryt, PhD
PhD Program in Physiology and Pathophysiology
University of Manitoba, Manitoba, CA
2016 Jinmo Gu
Dennis Guttridge, PhD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Sara Koening
Vidu Garg, MD
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Lindsey J. Anstine (was Miller)
Joy Lincoln
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PhD Program, Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2017 Stephanie LaHaye
Vidu Garg, MD
PhD Program in Molecular Genetics
The Ohio State University College of Medicine, Columbus, OH, USA
Rotation Student Advisees
2006 Yousuf Ali
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2007 Lakshmi Ganesan
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2008 Reema Ishteiwy
PhD Program in Molecular and Cellular Pharmacology
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Kristin Richards
PhD Program in Biomedical Sciences
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2010 Darrell Hardin
PhD Program in Biomedical Sciences
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2011 Yenong Cao
PhD Program in Biomedical Sciences
University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA
2013 Conrad Kiyoshi
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2013 Kirsten Schaffer
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2015 Adrianna Matos
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Donn Calkins
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PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Kevin Nelson
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Sanjana Rajan
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2016 Emily Nordquist
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2017 Sean Lein
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
2018 Monica Mannings
PhD Program in Molecular, Cell and Developmental Biology
The Ohio State University College of Medicine, Columbus, OH, USA
CONFERENCES AND SYMPOSIA 1. Organizer, University of Miami Cardiovascular Research Symposium: T32 training grant,
University of Miami, Leonard M. Miller School of Medicine, 2007-2010Invited Chair,
“Heart valve development”, Weinstein Cardiovascular Development Meeting, Cincinnati,
OH, USA, May 2011
2. Co-host, “2nd Annual Midwest Heart Valve Meeting, The Heart Center at Nationwide
Children’s Hospital, Columbus, OH, USA, September 2012
3. Co-host, “3rd Annual Midwest Heart Valve Meeting, The Heart Center at Nationwide
Children’s Hospital, Columbus, OH, USA, September 2013
4. Nominated Member, International Weinstein Cardiovascular Development Meeting, 2014-
Present
5. Co-host, Weinstein Cardiovascular Development and Regeneration Meeting 2017,
Columbus, OH, USA
LOCAL/REGIONAL DISTINGUISHED ACTIVITIES
1. Chair and Host, Cardiovascular Research Symposium, University of Miami, Leonard M.
Miller School of Medicine, 2007-2010
31
2. Chair, Department of Molecular and Cellular Pharmacology Faculty Chair Search
Committee, University of Miami, Leonard M. Miller School of Medicine, 2010
3. Captain, Nationwide Children’s Hospital American Heart Association Central Ohio Walk
Team, 2013-Present
4. Co-host, Midwest Heart Valve Meeting, The Heart Center at Nationwide Children’s
Hospital, 2012, 2013
5. Representative, Nationwide Children’s Hospital American Heart Association Central Ohio
Chapter, 2014-2016
NATIONAL/INTERNATIONAL DISTINGUISHED ACTIVITIES 1. Nominated Member, International Weinstein Cardiovascular Development Meeting, 2014-
Present
2. Member, Scientific Review Board, Basic Cell and Molecular Biology
American Heart Association National Region, 2007-2010
3. Ad-hoc Member, Scientific Review Board, Cardiac Differentiation and Development,
National Institute of Health (National Heart, Lung and Blood Institute), 2009
4. Member, Scientific Review Board, Cardiovascular Development III
American Heart Association National Region, 2011-Present
5. Member, Scientific Advisory Board; Cardiovascular Research
W. W. Smith Charitable Trust, 2013-Present
6. External Board Member, Micah Bachelor Award for Excellence in Children’s Health
Research, University of Miami, Leonard M. Miller School of Medicine, 2013
7. Member, Scientific Review Board, Innovative Grant Research Awards, American Heart
Association National Region, 2014
8. Nominated Member, International Weinstein Cardiovascular Development Meeting, 2014-
Present
9. Nominated Member, Women’s Leadership Committee, International Society of Applied
Cardiovascular Biology, 2016-Present
10. Co-Host, Weinstein Cardiovascular Development Meeting, Columbus 2017
11. Chair, Women’s Leadership Committee, International Society of Applied Cardiovascular
Biology
PROFESSIONAL MEMBERSHIPS AND ACTIVITIES
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1. American Heart Association Professional Member, 2008-Present
2. Member, American Society for Matrix Biology, 2008-Present
3. Member, British Society for Cardiovascular Research, 2010-2013
4. Member, Society for Developmental Biology, 2014-Present
5. Member, The Heart Valve Society, 2016-Present
6. Member, The International Society of Applied Cardiovascular Biology, 2016-Present