Post on 16-Jul-2015
transcript
Dementia
Dr nahed shehta
Definition: AEClinical pictureInvestigation treatment
DefinitionProgressive deterioration of memory
behavior personality
AE:DegenerativeNeurologicsystemic
Degenerative:AlzheimerFrontotemporalDementia with parkinsonism
SystemicEndocrine thyroidHeptic , renalNutritional B1, B6, B12, folatealchoholic
Neurological causesVascular dementiaTumers
FrontalTemporalCorpus callosum
NPHydrochephalusTrauma SDHInfection
AIDSHSimplex
Reading Speech
VisuospatialFunction
Speech motorcontrol
Alzheimer dementiaRisk factors1.Age2.Sex3.Education4.Alchol5.Repeated trauma6.Aluminum7.Family history
Famous people with alzheimer
Vascular dementiaRisk factors1.HPN2. DM3.Hyperlibidemia4.Recurrent strokes
Frontotemporal dementia selective frontal , temporal atrophy memory loss personality changes biopsy: picks cells in frontal,
Temporal lobes
investigation1.Lab
1. LFT, KFT , CBC (ANEMIA) , hormonal assay
2.Neuroimaging1. CT, MRI
1. Cortical atrophy2. Hippocampal atrophy3. lacunar infarct4. Frontotemporal atrophy5. NPH
NORMAL CT BRAIN
AXIAL CT for Alzheimer
CT for Alzhiemer
treatmentTarget: ↑ Ach
1. Cholinesterase inhibitors2. NMDA antagonists
glutamate tocicity3. Antidepressant4. Cerebral dilators5. Vitamins6. Estrogen replacement