Feature, Advantage & Benefit of Cefixime and Cefuroxime

Post on 25-May-2015

868 views 15 download

Tags:

description

Cefixime is an oral third generation cephalosporin. On the other hand, Cefuroxime is a second generation cephalosporin antibiotic. There are lot of feature, Advangtage and Benefit of these antibiotic. Here this issue is discussed briefly.

transcript

FEATUREADVANTAGE &BENEFIT (FAB) Presenter:

Shuman Chandra Das

Brand Executive, Asiatic

Switch Therapy

1) Afixime is considered as first choice of switch therapy because it has similar chemical structure, bacterial coverage and efficacy like Ceftriaxone which is used as parenteral therapy antibiotic in hospital. As a result patients gets less costly alternative after reaching home.

Typhoid Fever

2) Afixime is called drug of choice in Typhoid fever because it shows highest sensitivity (83%) against causative pathogens Salmonella typhi or Salmonella paratyphi comparatively than Amoxicillin (46%), Azithromycin (43%). So, patients gets maximum efficacy in minimum dose.

UTI

3) Cefixime is better treatment option than Ciprofloxacin in UTI. The susceptibility rate of Ciprofloxacin against E.coli is only 77% whereas Cefixime ensures 96%. However, in case of resistance, Cefixime is only 15% resistant whereas Ciprofloxacin in 70% resistant.

Manufacture

4) Afixime ensures best quality as it is manufactured in separate and a dedicated cephalosporin section. However, the manufacturing methods follow WHO approved cGMP guidelines.

Raw Material

5) Asiatic ensures qualitative raw material of Cefixime Trihydrate. The raw materials are imported from USFDA, UKAS and ISO certified sources. As a result Cefixime confirms highest purity and quality.

Antimicrobial Coverage

1) Ceroxime has wider antimicrobial coverage. Many antibiotics are effective either against gram (+) or gram (-) bacteria but Ceroxime has outstanding cure rate against both of these organism as well as against anaerobic bacteria. As a result patient gets maximum benefit.

Resistance

2) Ceroxime is less resistant compared to other antibiotics. It has methoxy imino group in its chemical structure which shields form resistance. As a result Ceroxime ensures better clinical success rate than other antibiotics.

Pregnancy

3) Ceroxime is the safest antibiotic used in pregnancy. Other antibiotic such as aminoglycosides, Tetracycline and Gyrase inhibitors are contraindicated in pregnancy. This is why Ceroxime is used in pregnancy as the first-line antibiotic.

Dosage guideline

4) The dosage guideline of Ceroxime is easy and flexible. Patients have to take once or twice daily instead of three or four times daily. As a result it lowers chance of dose missing and ensures patients compliance.

Dental Infection

5) Ceroxime is better than Cefaclor in case of Acute Dental Infection. The clinical success rate of Ceroxime is 90% whereas Cefaclor ensures only 75% success rate. This is why it is clear that Ceroxime is antibiotic of choice in Dental Infection.

THANK YOUBYE BYE &TA TA… Presenter:

Shuman Chandra Das

Brand Executive, Asiatic