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Flow Diagram of the Main HOPE Trial and the HOPE-TOO Trial Extension
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Baseline Characteristics
of All HOPE Study Patients
and of the Patients at
Centers Continuing in
the Trial Extension
(HOPE-TOO)
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Incidence and Relative Risks of Cancers and Deaths Due to Cancer
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Kaplan-Meier Analysis of the Effects of Vitamin E on Incident Cancer and
Major Cardiovascular Events for All 9541 Study Patients
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Incidence and Relative Risks of Site-Specific Cancers
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Incidence and Relative Risks of Major Vascular Events, Deaths, and Secondary
Cardiovascular Outcomes
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Kaplan-Meier Analysis of the Effects of Vitamin E
on All Heart Failure Events and Hospital Admissions
for Heart Failure in HOPE and HOPE-TOO Patients
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347
Lung Cancer in Large Randomized Trials of Vitamin E
The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338-1347