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GNIPST BULLETIN 2013
15th March 2013 Volume No.: 23 Issue No.: 03
ContentsMessage from GNIPS
Letter to the EditorNews Update
Disease Outbreak Ne
Health Awareness
Forth Coming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
Vision
TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O
PHARMACEUTICAL AND BIOLOGICAL SCIENCE
EDITOR: Debabrata Ghosh DastidarGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE ANDTECHNOLOGY
GNIPST Photo Gallery
For your comments/contributionOR
For Back-Issues,
mailto:gnipstbulletin@gmail.com
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MESSAGE FROM GNIPSTAll the members of GNIPST are proud to publish the 23rdVolume of
GNIPST BULLETIN. This bulletin has successfully completed its
twenty months journey. We hope it has kept the readers updated of
recent activities in pharmaceutical & biological sciences and also
introduced them with the different activities of our esteemed
institution. We are thankful to all of you for your great cooperation
& support and are looking forward to the same in future.
LETTER TO THE EDITOR.
NEWS UPDATE
Temp-Controlled 'Nanopores' May Allow Detailed
Blood Analysis (08 MARCH 2013)Tiny biomolecular chambers called nanopores that can be
selectively heated may help doctors diagnose disease more
effectively, according to a new research.Read moreAnti-Aging Drug Breakthrough (08 MARCH 2013)
Drugs that combat aging may be available within five years,
following landmark work. The work finally demonstrates that a
single anti-aging enzyme in the body can be targeted, with the
potential to prevent age-related diseases and extend lifespans. Four
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thousand synthetic activators, which are 100 times as potent as a
single glass of red wine, have been developed -- the best three are in
human trials.Read more
Biological Tooth Replacement Is a Step Closer.
(08 MARCH 2013)
Scientists have developed a new method of replacing missing teeth
with a bioengineered material generated from a person's own gum
cells. Current implant-based methods of whole tooth replacementfail to reproduce a natural root structure and, as a consequence of
the friction from eating and other jaw movement, loss of jaw bone
can occur around the implant.Read more
Length of DNA Strands Can Predict Life
Expectancy (09 MARCH 2013)
Can the length of strands of DNA in patients with heart disease
predict their life expectancy? Researchers who studied the DNA of
more that 3,500 patients with heart disease, say yes it can.Read moreStore Donated Blood for More Than 3 Weeks?
Say NO (Nitric Oxide) (10 MARCH 2013)
Transfusion of donated blood more than three weeks old results in
impaired blood vessel function, a new study of hospital patients
shows. Blood banks now consider six weeks to be the maximum
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permitted storage time of blood for use in transfusion, but recent
studies have suggested transfusing blood stored for more than a few
weeks has adverse effects in patients undergoing cardiac surgery or
critical care.Read more Aspirin May Lower Melanoma Risk
(11 MARCH 2013)
A new study has found that women who take aspirin have a reduced
risk of developing melanoma -- and that the longer they take it, the
lower the risk. The findings suggest that aspirin's anti-
inflammatory effects may help protect against this type of skin
cancer.Read more Immune Cells Cluster and Communicate 'Like
Bees,' Researcher Says (13 MARCH 2013)
The immune system's T cells, while coordinating responses to
diseases and vaccines, act like honey bees sharing information
about the best honey sources, according to a new study.Read more Bitter Melon JuicePrevents Pancreatic Cancer in
Mouse Models (12MARCH 2013
)A new study shows that bitter melon juice restricts the ability of
pancreatic cancer cells to metabolize glucose, thus cutting the cells'
energy source and eventually killing them.Read more
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Computer Models Predict How Patients Will
Respond to HIV Drugs Without the Need for
Resistance Testing (14 MARCH 2013)
Computer models can predict how HIV patients whose drug
therapy is failing will respond to a new treatment. Crucially for
patients in poorer countries, the models do not require the results
of expensive drug resistance tests to make their predictions. The
study also showed that the models were able to identify alternativedrug combinations that were predicted to work in cases where the
treatment used in the clinic had failed, suggesting that their use
could avoid treatment failure.Read more Tobacco Industry Appears to Have Evaded FDA
Ban On 'Light' Cigarette Descriptors
(13 MARCH 2013)
New research shows one year after the U.S. government passed a
law banning such descriptors as "light," "mild," and "low" on
cigarette packages, smokers can identify their brands because of
color-coding that tobacco companies added to "light" packs afterthe ban. These findings suggest the companies have been able to
evade the ban on misleading wording and still convey false and
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deceptive message that lights are safer than "regular" cigarettes.
Read more Goats' Milk With Antimicrobial Lysozyme Speeds
Recovery from Diarrhea (13 MARCH
2013)
Milk from goats that were genetically modified to produce higher
levels of lysozyme, a human antimicrobial protein, has proved
effective in treating diarrhea in young pigs and may one day be usedto help prevent human diarrheal diseases that each year claim the
lives of 1.8 million children around the world.Read more
HEALTH AWARENESS
LYMPHATIC FILARIASIS
Lymphatic filariasis, commonly known as
elephantiasis, is a neglected tropical disease.
Infection occurs when filarial parasites are
transmitted to humans through mosquitoes.
When a mosquito with infective stage larvae
bites a person, the parasites are deposited on the
person's skin from where they enter the body. The larvae then
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migrate to the lymphatic vessels where they develop into adult
worms in the human lymphatic system.
Infection is usually acquired in childhood, but the painful and
profoundly disfiguring visible manifestations of the disease occur
later in life. Whereas acute episodes of the disease cause
temporary disability, lymphatic filariasis leads to permanent
disability.
Currently, more than 1.4 billion people in 73 countries are at risk.
Approximately 65% of those infected live in the WHO South-EastAsia Region, 30% in the African Region, and the remainder in
other tropical areas.
Lymphatic filariasis afflicts over 25 million men with genital
disease and over 15 million people with lymphoedema. Since the
prevalence and intensity of infection are linked to poverty, its
elimination can contribute to achieving the United Nations
Millennium Development Goals.
Cause and transmission
Lymphatic filariasis is caused by infection with nematodes(roundworms) of the family Filariodidea. There are three types of
these thread-like filarial worms:
Wuchereria bancrofti, which is responsible for 90% of the cases
Brugia malayi, which causes most of the remainder of the cases
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B. timori, which also causes the diseases.
Adult worms lodge in the lymphatic system and disrupt the
immune system. They live for 6-8 years and, during their life time,
produce millions of microfilariae (small larvae) that circulate in
the blood.
Lymphatic filariasis is transmitted by different types of
mosquitoes for example by the Culex mosquito, widespread
across urban and semi-urban areas; Anopheles mainly in rural
areas, and Aedes, mainly in endemic islands in the Pacific.
Symptoms
Lymphatic filariasis infection involves asymptomatic, acute, and
chronic conditions. The majority of infections are asymptomatic,
showing no external signs of infection. These asymptomatic
infections still cause damage to the lymphatic system and the
kidneys as well as alter the body's immune system.
Acute episodes of local inflammation involving skin, lymph nodes
and lymphatic vessels often accompany the chronic lymphoedema
or elephantiasis. Some of these episodes are caused by the body'simmune response to the parasite. However most are the result of
bacterial skin infection where normal defences have been partially
lost due to underlying lymphatic damage.
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When lymphatic filariasis develops into chronic conditions, it
leads to lymphoedema (tissue swelling) or elephantiasis
(skin/tissue thickening) of limbs and hydrocele (fluid
accumulation). Involvement of breasts and genital organs is
common.
Such body deformities lead to social stigma, as well as financial
hardship from loss of income and increased medical expenses. The
socioeconomic burdens of isolation and poverty are immense.
Treatment and prevention
The recommended regimen for treatment through mass drug
administration (MDA) is a single dose of two medicines given
together - albendazole (400 mg) plus either ivermectin (150-200
mcg/kg) in areas where onchocerciasis (river blindness) is also
endemic or diethylcarbamazine citrate (DEC) (6 mg/kg) in areas
where onchocerciasis is not endemic. These medicines clear
microfilariae from the bloodstream.
Mosquito control is another measure that can be used to suppress
transmission. Measures such as insecticide-treated nets or indoorresidual spraying may help protect populations in endemic
regions from infection.
Patients with chronic disabilities like elephantiasis,
lymphoedema, or hydrocele are advised to maintain rigorous
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hygiene and take necessary precautions to prevent secondary
infection and aggravation of the disease condition.
DISEASE OUTBREAK NEWS
FORTHCOMING EVENTS
DRUGS UPDATES
FDA approves Lymphoseek to help locate lymph
nodesin patients with certain cancers (13
FEBRUARY 2013)
The U.S. FDA approved Lymphoseek (technetium Tc 99mtilmanocept) Injection, a radioactive diagnostic imaging agent that
helps doctors locate lymph nodes in patients with breast cancer or
melanoma who are undergoing surgery to remove tumor-draining
lymph nodes. Read more
CAMPUS NEWS
The poster Oolong tea as a source of natural antioxidant, presented
in the national seminar, organized by GNIT, Panihati, Kol-114, by
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Anirban Banerjee (M.Pharm., 1st yr.), Dibya Das (B.Pharm., 4th yr.),
Rahul Deb Mondal (M.Pharm., 1st yr.), was awarded third prize.
STUDENTS SECTION
WHO CAN ANSWER FIRST???() William and James Horlick were associated
with invention of which patented food
product?
() Which type of classification system wascreated by Melvil Dewey?
Answer of Previous Issue Question:A) Pseudomonus putida B)Keypad
Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Section
& answers of this Section at gnipstbulletin@gmail.comEDITORS NOTE
I am very happy to publish the 3rd issue of 23rd Volume of GNIPST
BULLETIN. It is my great pleasure to introduce you to the newly
launched facebook account GNIPST bulletin. You are cordially
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invited to add this account to your friend list. The current issues will
also be directly available on facebook.
I would like to convey my thanks to all the GNIPST members and
the readers for their valuable comments, encouragement& supports.
Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya
Bhattacharya, for his contribution instudents section.
It would be my great pleasure to receive the contributions,
suggestions & feedback from your desk for further upliftment of this
deliberation GNIPST BULLETIN.
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ARCHIVE
The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15th
June, 2012. The programme startedwith a nice presentation by Dr. Pulok Kr. Mukherjee, School of
Natural Products, JU on the skill to write a good manuscript for
publication in impact journals. It was followed by nearly two hour
long discussion among more than thirty participants on different
aspects of pharmacy education. Five nonmember participants
applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm) in
PHARMACOLOGY. The approved number of seat is 18.The number of seats in B.Pharm. has been increased from 60 to 120.
2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),
Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry
(SWC-2013) : On the Way to Personalized Medicine
Dates 28 Feb 2013 02 Mar 2013
Location: Chandigarh, India.Details. AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-
13to GNIPST as per the details below:
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a. Beneficiary Institution: Guru Nanak Institution of
Pharmaceutical Science & Technology.
b. Principal Investigator: Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- only
d. Approved duration: 3 years
e.Title of the project: Screening and identification of potential
medicinal plant ofPurulia&Bankuradistricts of West Bengal with
respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancingbioactive molecules in these plant.
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