Since 1988 High Force Research has worked

with organizations operating in practically all end

use sectors requiring chemical synthesis input,

and offers a range of services allied to new

product development

History

Durham

Meet the team

Chairman

Bob Redfern

CEO

Roy Valentine

Research Manager

Nicola Lembicz

Research Chemists

Development Manager

Barry Thompson

Development Chemists

Head of Quality

Zoe Lilburn

QA Department QC Department

Head of Business Development

Stella James

Marketing

Operations Director

Stuart Penny

GMP Chemists

• 30 staff, one third PhD’s

• Highly experienced team of chemists and analysts

• Pharmaceutical

• Biotechnology

• Diagnostics

• Imaging

• Agrochemical

• Organic Electronics

• Performance materials

• Polymers

• Coatings

• Fine Chemicals

Who we work with

• Multinationals

• SME’s

• Start-ups

• Spin-outs

• Virtual Enterprises

• Universities

• Charities

• Institutes

Who we work with

• Chemical R&D

- milligram to kilo scale

• Process Development

- route design, development

& optimisation

- improve yields

- reduce the number of steps

- reduce batch cycle times

- eliminate the use of

hazardous materials

How we can help

• Contract Synthesis

- Building blocks &

intermediates

- Patent analogues

- Non-literature targets

- Client proprietary

compounds

- Reference standards

- Drug impurity compounds

- Metabolites

How we can help

• Scale-up

- gram to kilo

• Analysis

- analytical services and

method development

• Consultancy

How we can help

• Traceable Manufacture

- Pre-clinical studies

- API starting materials

- Performance materials

• GMP (MHRA inspected)

- Analytical Development

- Validation

- Stability Studies

- Auditing

- Reference substances

How we can help

• 1100 m2 of laboratory space

• 30 x Fume cupboards

• 2 x Class 8 clean rooms

• Jacketed glassware to 30L at -

40 to 180oC

• Pressure vessels to 7L

• Ability to handle HF

• Mass Spectrometry

Facilities

• Multinuclear 400Mhz NMR

• HPLC (UV, DAD)

• FTIR (ATR)

• Karl Fischer

• DSC

• Classical wet analysis

• GLC (Liquid and Headspace)

• Size Exclusion Chromatography

• Optical rotation

Facilities

• Elemental Analysis

• XRPD

• Solid State NMR

• Raman Spectroscopy

• Surface Analysis

- SEM,TEM, XRF etc.

• LC-ICP-MS

• Microbiology

Access to advanced techniques

• For over 27 years, HFR has

supported the pharmaceutical

and chemical industry in their

medical and scientific advances

• Collaborate with companies at

the proof of concept stage of

their product or technology life

cycle

• Expert in developing and

scaling up complex syntheses

of molecules used by

researchers

Why choose HFR?

• The only independently owned

UK business that works to GMP

on small scale production only

audited by the MHRA for early

stage clinical trials

• Flexible & adaptable approach

to chemical synthesis. Working

collaboratively to achieve the

highest quality compounds from

gram to kilo with products

delivered to specification, on-

time and safely

Why choose HFR?

Contact us:

Head of Business Development

Stella James

+44 (0) 744 358 7141

stellajames@highforceresearch.com

www.highforceresearch.com