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Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Confession
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Specialist in fertility and IVF techniques
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Five-step process
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
The accident
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
The accident repeated
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Stem cells
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Established stem cell lines
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Regulations and guidelines
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Continuous iteration
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
No ban
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Recommendations may change with time
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Enabling structure
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Product acceptance and release criteria
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
IC-SCRT / NAC-SCRT
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Records, no hype, scientific evidence
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Data for over 1,200 patients
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
GLP, GMP and GCP certifications
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Regulatory environment
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
France
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Germany
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Italy
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
The UK
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
China
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
The USA
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
National Institutes of Health Guidelines on
Human Stem Cell Research
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Singapore
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
No specific legislation in Singapore
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Singapore chimeras
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
What have I done differently?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Only one embryo
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Non-chimeric
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Treatment outcomes
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Assessment standards and scales
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Holistic, sensitive and workable score
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Some cases
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
2 June 2011 11 November 2011
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
19 June 2012 16 July 2012
26-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
16 July 2012 2 June 2011
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
25-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
After Before
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
8 November 2011 3 January 2012
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
7 March 2012 6 November 2012
46-year old male
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
6 November 2012 8 November 2011
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Day 10 Day 2
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Day 26 Day 19
45-year old female
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Day 26 Day 1
Ready-to-use form
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
International patent
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Easy clinical application
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Incurable and chronic conditions and illnesses
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Treatment protocol developed over the years
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
30% are doctors, 30% from 36 countries
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Towards commercialisation
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Virtual patent ban in the EU
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
How can innovation come from the third world?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Two basic questions
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
When does a developing embryo become human?
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Questions only for hESC research and treatment
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
No problems with IVF
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Wastage of nearly 1.7 million embryos in the UK
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Termination of pregnancy
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Morning-after pill acceptable
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Safe and efficacious therapeutic effects
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
No matching, no testing
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
First line of treatment for many of mankind’s worst
afflictions
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Cogent, unblinkered policy framework
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
What lies ahead is still not firm and final
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Review, accept and adapt
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Thinking of the patient first
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
No more Savitas
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Death triumphed where life should have
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
It is time we acted
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London
Thank you!
Human Embryonic Stem Cell Treatment An Indian Perspective
Presentation by Dr Geeta Shroff 15 March 2013 • King’s College, London