Immune transcriptional responses to viral infections

Post on 09-May-2015

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description

Using changes in gene expression to diagnose different types of viral diseases (lassa virus, marburg virus) Image credit Monkey by Christy Presler from The Noun Project Megaphone by Mister Pixel from The Noun Project Drop by matthew hall from The Noun Project

transcript

Immune transcriptional

responses to viral infections

nacho caballero

marburg lassa

macaque

read count 42

rnaimmune cellsblood sample

sequence

IFIT1

vs.

direct infection

distress signal

interferon

ISGs

IFIT1

Fold

cha

nge

(log

2)

Days post-infection

Lassa Marburg

Common response

Unique response

Candidate biomarkers

Microarray validationco

mp

onen

t 1

component 2

M1

M3M5

L6

L3

Compare additional viruses

Analyze human samples

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