Importance of Importance of Vitamin D In Vitamin D In Pregnancy & Pregnancy &

LactationLactation

A High Prevalence of Vitamin D

Deficiency Is Now Recognized in

PREGNANT WOMENPREGNANT WOMEN

2002;76:187-192.

Vitamin D deficiency is now

recognized as a PANDEMIC PANDEMIC

2008 Apr;87(4):1080S-6S.

Vitamin D Deficiencies have been

prevalent even in studies where over

90%90% of the women took prenatal

vitamins

2007;137:447-452.

High Prevalence of Vitamin D

Deficiency Was Found in

Nursing MothersNursing Mothers and

Their Infants Predominantly in the

Upper Socioeconomic Class

1998, vol. 77, no10, pp. 970-973

In Pakistan

Vitamin D Deficiency Affects

FETAL GROWTHFETAL GROWTH Through

an Effect on Maternal Calcium

Homeostasis.

1996 Jul 5;45(1-2):27-33.

Maternal Vitamin D Insufficiency Is Common During Pregnancy and Is Associated With

REDUCED BONE-REDUCED BONE-

MINERAL ACCRUALMINERAL ACCRUAL

in the Offspring During Childhood

2006;367:36-43.

Evidence Is Accumulating That Even

Less Severe Vitamin D Deficiencies in Utero May

Affect

IMMUNE FUNCTIONIMMUNE FUNCTION &

BONE DEVELOPMENTBONE DEVELOPMENT

From Birth Through Adulthood

2006;174:1287-1290.

Low Maternal 25-(OH)D in Late Pregnancy

Is Associated With Reduced

INTRAUTERINE LONG INTRAUTERINE LONG

BONE GROWTHBONE GROWTH and SlightlySlightly

SHORTER GESTATIONSHORTER GESTATION

2006 Mar;91(3):906-12.

LOW BIRTH WEIGHTLOW BIRTH WEIGHT

Has Been Associated With Low

Maternal Vitamin D Levels

2006;174:1273-1277

The Rising Prevalence of

ASTHMA ASTHMA (In Children), May

Also Be a Sequela of Low Levels of

Vitamin D in Pregnant Women

2008;62:68-77.

MATERNAL VITAMIN D MATERNAL VITAMIN D

DEFICIENCYDEFICIENCY During Pregnancy

and During the Period of Breastfeeding Contributes to the

Development of RICKETS IN RICKETS IN

INFANCYINFANCY

2005;147:109–111

Maternal vitamin D deficiency may be an

independent risk factor for

PRE-ECLAMPSIAPRE-ECLAMPSIA

With increasing vitamin D levels, the risk

for pre-eclampsia was significantly

reduced

2007 Sep;92(9):3517-22.

Vitamin D Supplementation of the

Breast-feeding Mother at Risk and

Her Infant Is Recommended

1997 Jan-Feb;17(1):10-4.

The Administration of a Single Low Dose

of Vitamin D3 (100,000 I.U.)Vitamin D3 (100,000 I.U.)

On the Sixth or Seventh Month Sixth or Seventh Month

of Pregnancyof Pregnancy Allowed to Prevent

Serum Calcium and 25-(OH)D

Concentrations

1988;17(8):1099-105.

A single 5-mg (200,000 IU) dose of

vitamin D

CHOLECALCIFEROLCHOLECALCIFEROL

given orally at the seventh month

of pregnancy provides effective

prophylaxis

1986 Sep;68(3):300-4.

Oral / IM Ampoule

Containing

5mg Cholecalciferol eq to

200,000 IU Cholecalciferol

Light Resistant

Ampoule Packaging

Dose

Prevention

½ to 1 ampoule (100,000 IU – 200,000 IU) at

6th or 7th month of pregnancy

Oral / IM

Appreciation by Central Licensing Authority

““State Of The Art State Of The Art

Manufacturing FacilityManufacturing Facility”

Islamabad 14th February 2009

ITALIANITALIAN Source of Raw Source of Raw

MaterialMaterial

Better Light Resistant Packaging

Better Source of Raw Material

Better Manufacturing Facility

Why Pay 115 Rupees Why Pay 115 Rupees

More ???More ???

Thank YouThank You