Post on 11-Jan-2016
transcript
JE “DNA Introduction”
1. What do you already know about DNA?•Where do you hear about it? Why?•What does DNA stand for? •What does it look like?•Where is it?•What is the code?•DRAW something2. Why should we learn about it? 3. What do you want to know about DNA?
Welcome to Biology!
Pop Stars
At The Grammys Concert
Walking the RED carpet
DNA structure
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Phosphate
Sugar
Adenine
Thymine
Guanine
Cytosine
Wound up in Double Helix
Unwound
SPSP
Wound up in Double Helix
Where on the red carpet are the Pop Stars?
Who is in the middle of the red carpet?
How do those in the middle of the red carpet pair up?
DNA has a Double Helix Shape
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Nucleotide:A subunit of DNA that contains a phosphate, a sugar and a nitrogenous base.
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What are the three parts of a Nucleotide?
a phosphate, a sugar and a nitrogenous base.
What part of the nucleotide is the Nitrogenous base?
A, T, G, and C are the 4 nitrogenous bases.
A
A
G G
T
T
C C • Guanine with Cytosine
in 3 hydrogen bonds
• Adenine with Thymine in 2 hydrogen bonds.
• Cytosine and Thymine are single rings and small.
Why is A only with T and G only with C?
• Adenine and Guanine are double rings and big.
Where is the co
de?
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DNA Code
• The code is carried in the sequence of nitrogenous bases that are on the inside.
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DNA Code
• adenine (A) pairs with thymine (T)• guanine (G) pairs with cytosine (C)
AC TG CCGG TT A A
T T TG GGC CCA A AWhat is the code of the lower strand of
this DNA sequence?
DNA code
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The gene for the protein “Human MKK6”1 agttccaagt ttggagcttt tagctgccag ccctggccca tcatgtagct gcagcacagc tccctaac gttgcaactg ggggaaaaat cactttccag tctgttttgc aaggtgtgca ttccatctt gattccctga aagtccatct gctgcatcgg tcaagagaaa ctccacttgc atgaagattg cacgcctgca gcttgcatct ttgttgcaaa actagctaca gaagagaagc aaggcaaagt cttttgtgct cccctccccc atcaaaggaa aggggaaaat gtctcagtcg aaaggcaaga agcgaaaccc tggccttaaa attccaaaag aagcatttga acaacctcag accagttcca caccacctcg agatttagac tccaaggctt gcatttctat tggaaatcag aactttgagg tgaaggcaga tgacctggag cctataatgg aactgggacg aggtgcgtac ggggtggtgg agaagatgcg gcacgtgccc agcgggcaga tcatggcagt gaagcggatc cgagccacag taaatagcca ggaacagaaa cggctactga tggatttgga tatttccatg aggacggtgg actgtccatt cactgtcacc ttttatggcg cactgtttcg ggagggtgat gtgtggatct gcatggagct catggataca tcactagata aattctacaa acaagttatt gataaaggcc agacaattcc agaggacatc ttagggaaaa tagcagtttc tattgtaaaa gcattagaac atttacatag taagctgtct gtcattcaca gagacgtcaa gccttctaat tactcatca atgctctcgg tcaagtgaag atgtgcgatt ttggaatcag tggctacttg gtggactctg ttgctaaaac aattgatgca ggttgcaaac catacatggc ccctgaaaga ataaacccag agctcaacca gaagggatac agtgtgaagt ctgacatttg gagtctgggc atcacgatga ttgagttggc catccttcga tttccctatg attcatgggg aactccattt cagcagctca aacaggtggt agaggagcca tcgccacaac tcccagcaga caagttctct gcagagtttg ttgactttac ctcacagtgc ttaaagaaga attccaaaga acggcctaca tacccagagc taatgcaaca tccatttttc accctacatg aatccaaagg aacagatgtg gcatcttttg taaaactgat tcttggagac taaaaagcag tggacttaat cggttgaccc tactgtggat tggtgggttt cggggtgaag caagttcact acagcatcaa tagaaagtca tctttgagat aatttaaccc tgcctctcag agggttttct ctcccaattt tctttttact ccccctctta agggggcctt ggaatctata gtatagaatg aactgtctag atggatgaat tatgataaag gcttaggact tcaaaaggtg attaaatatt taatgatgtg tcatatgagt cctcaagctt ctcagacttc tcttattctt tacaaaatga atgcattggc cctgacaaaa aggtgctacg gtagtgatga aattataagt agatttgtag tttgtcccat ttattatttt aatatttatg tttaagtgct tggttgaaaa gattccattt tatacaagaa gggagattca aaaaaaaaat ataaggttgg gttagcaata tttatagggc ttttattttt taagttcaat tgtgtctgtg gtccagaaga aattatttaa tatgcatctt tgagaatatt ataaaaatat caaaaaggaa aaaaaaaaa
http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=90577186
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Partners
Tell the story of what the Pop Stars at the Grammys Concert has to do with
DNA Structure
DNA Ticket out the Door1. Label the DNA with these letters: P S A T G C• (The nucleotides may go in any order)
2. Circle and label a nucleotide.3. Circle and label the hydrogen bonds.4. Write the “code” of one strand of the DNA you made.
P
P
P
P
P
PS
S
S
S
S
S A
A
G
T
C
T
nucleotide
Hydrogenbonds
Code: AGT
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THE END
P
P
P
P
P
PS
S
S
S
S
S A
A
G
T
C
T
Name: _____________
P
P
P
P
P
PS
S
S
S
S
S A
A
G
T
C
T
Name: _____________
P
P
P
P
P
PS
S
S
S
S
S A
A
G
T
C
T
Name: _____________
P
P
P
P
P
PS
S
S
S
S
S A
A
G
T
C
T
Name: _____________