Post on 14-Feb-2016
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transcript
Alcohol and AIDS: A New Decade
Grantsmanship Workshop XIX International AIDS Conference
Rome, Italy
Kendall J. Bryant, Ph.D. , NIAAAAlcohol and AIDS Research
National Institutes of Health
NIAAA Vision Statement for prevention and treatment of HIV/AIDS
To support and promote the best science on alcohol and health:– Improving the diagnosis, prevention, and treatment of
alcohol use disorders to reduce new HIV infections and improve treatment outcomes
– Increasing the understanding of normal and abnormal biological functions and behavior relating to alcohol use and HIV infection
– Enhancing the quality of health and health care delivery in domestic and international settings to reduce morbidity and mortality
Prevention of New Infections
• Multilevel Ecological Research• Behavioral Risk Reduction: High-risk groups, Social
Networks, and Concurrency, Event-Level Factors• Alcohol Interventions include Brief Motivational,
Cognitive Behavioral, and Pharmacotherapy in At-Risk Populations
• NIAAA FY2010 P01 Integrative Behavioral Prevention Research
• International HIV Prevention in Venue Based Settings (R01)
Multilevel Models
Alcohol Use: One of many issues in HIV+ patients life
Neurologic Effects
Immunologic Effects
Liver Damage
Depression
Substance Abuse
Treatment
HIV Treatment
Alcohol Use
Neuropathogenesis andPain ManagementHCV coinfection,HBV and chronic viral loadOther drugs Quality of LifeAccess to treatment
NIAAA Portfolio : Funded 2010/11 Funded Initiatives
• Alcohol Pharmacotherapy for HIV+ • Centers for Integrative Research (P60, Consortiums)• Multilevel Preventive Interventions – Design and Testing• High-Risk Populations for Infection and Transmission:
Migrant Workers, Cross-Border Settings, Youth• Interagency Agreements for Collaborative Women and
Pediatric Cohorts• Developing International Networkers Alcohol HIV
Researchers• Targeted Initiatives: District of Columbia, Baltimore
New Models for Studying Progression and Aging
Implementation and Operations Research
• Develop Models of Interaction of Alcohol and HIV Prevention and Treatment Access and Uptake (and Comparative Effectiveness)
• Develop Models for Clinical Decision Making in Specific Settings for Patients, Providers, and Policy Makers
• Develop Identification, Screening, and Intervention Models (Seek, Test, and Treat) for Spectrum of Alcohol Use Disorders
Algorithm for integrating alcohol screening and treatment into clinical care of HIV patients
International Prevention