Post on 31-Mar-2015
transcript
Last Updated 2013-11-06
Company Profile
Rapid membrane test – Dipstick - Methodology
Human Rapid Tests - Dipstick:
Enteric products – Respiratory products – Gastric products – Drug Range
Uni-Strip Range
Rapid membrane test – Cassette – Methodology
Human Rapid Tests - Cassette:
Enteric products – Respiratory products – Gastric products - Other
V-TesT Gravity – Methodology - Product
Oligochromatography – Methodology - Products
Veterinary Rapid Tests
SummarySummary
Coris BioConcept was founded in 1996 by 2 biologists and 2 investors.
It is a biotechnology company offering innovative, rapid solutions to biomedical and research laboratories. The achievement of « Quality » is a consideration in all CORIS’ activities.
Coris BioConcept produces and markets diagnostic kits for the rapid detection of pathogens involved in infectious diseases.
24 persons presently work in the company.
Coris BioConcept is present in more than 80 countries in the 5 continents.
To meet the demands of its customers, Coris BioConcept works in a QC/QA frame.
The Quality Policy has been certified ISO 9001:2008 and ISO 13485:2003 by SGS.
Moreover all Coris BioConcept’s products fulfil the CE marking requirements.
Company ProfileCompany Profile
Coris BioConcept has developed mainly rapid kits to detect human enteric and respiratory pathogens. Tests are suitable for single sample analysis, require minimal sample manipulation and give unequivocal diagnostic within 5 to 15 minutes for positive samples. No sophisticated extra material is required to perform the test.
Rapid membrane testRapid membrane test
Test are performed on coated nitrocellulose strips and results are observed with colloidal gold particles or latex microspheres.
Once the strip is dipped into diluted sample, liquid samples and conjugate(s) migrate by capillary movement.
At the end of the migration process, one or two coloured lines appear indicating either a negative or a positive result respectively.
Dipstick - Methodology Dipstick - Methodology
Human Rapid Tests: Enteric Products Human Rapid Tests: Enteric Products
Rota-Strip > Rapid test to detect ROTAVIRUS in stool (C-1001)
Adeno-Strip > Rapid test to detect ADENOVIRUS group A to F in stool (C-1002)
40/41 Adeno-Strip > Rapid test to detect ADENOVIRUS group F (40/41) in stool (C-1003)
Combi-Strip > Rapid test to detect both ROTAVIRUS and ADENOVIRUS group A to F in stool (C-1004)
Crypto-Strip > Rapid test to detect CRYPTOSPORIDIUM in stool (C-1005)
Human Rapid Tests: Enteric Products (2)Human Rapid Tests: Enteric Products (2)
O157 Coli-Strip > Rapid test to detect ESCHERICHIA COLI O157 after broth enrichment (C-1011)
Giardia-Strip > Rapid test to detect GIARDIA in stool (C-1013)
GastroVir-Strip > Rapid test to detect both ROTAVIRUS and ADENOVIRUS group F (40/41) in stool (C-1016)
Crypto/Giardia Duo-Strip > Rapid test to detect both CRYPTOSPORIDIUM and GIARDIA in stool (C-1018)
C. diff-Strip > Rapid test to detect CLOSTRIDIUM DIFFICILE in stool (C-1020)
Human Rapid Tests: Respiratory Human Rapid Tests: Respiratory Products Products
RSV Respi-Strip > Rapid test to detect RESPIRATORY SYNCYTIAL VIRUS in nasopharyngeal specimens (C-1006)
Adeno Respi-Strip > Rapid test to detect RESPIRATORY ADENOVIRUS in nasopharyngeal secretions and/or culture supernatants (C-1009)
Influ-A&B Respi-Strip > Rapid test to detect INFLUENZA A and INFLUENZA B VIRUS in swabs, washings or aspirates of nasopharyngeal secretions
(C-1012)
Human Rapid Tests: Gastric Products Human Rapid Tests: Gastric Products
Pylori-Strip > Rapid test to detect HELICOBACTER PYLORI in stool (C-1019)
Human Rapid Tests: Drug RangeHuman Rapid Tests: Drug Range
Mefloquine-Strip> In vitro rapid test for detection of Mefloquine in urine
Proguanil-Strip > In vitro rapid test for detection of Proguanil in urine
Enteric ProductsEnteric Products
Rota-Strip:Rota-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
Rota Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Adeno-Adeno-Strip:Strip:
General Information
Product File
Advantages of the kit
Instructions for use
Adeno Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
40/41 Adeno-Strip:40/41 Adeno-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
40/41 Adeno Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Combi-Strip:Combi-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Crypto-Strip:Crypto-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
Crypto Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
O157 Coli-Strip:O157 Coli-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
O157 Coli Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Giardia-Strip:Giardia-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
GastroVir-Strip:GastroVir-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Crypto/Giardia Duo-Crypto/Giardia Duo-Strip:Strip:
a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
General Information
Product File
Advantages of the kit
Instructions for use
Crypto/Giardia Uni-Strip
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
C. diff-Strip:C. diff-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Respiratory ProductsRespiratory Products
RSV Respi-Strip:RSV Respi-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Respiratory ProductsRespiratory Products
Adeno Respi-Strip:Adeno Respi-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Respiratory ProductsRespiratory Products
Influ-AInflu-A&&B Respi-Strip:B Respi-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
Influ-A&B Uni-Strip a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
Gastric ProductsGastric Products
Pylori-Strip:Pylori-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Drug RangeDrug Range
Mefloquine-Strip:Mefloquine-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Drug RangeDrug Range
Proguanil-Strip:Proguanil-Strip:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Advantages of dipstick kits Advantages of dipstick kits
SENSITIVE
SPECIFIC
SIMPLE
EASY TO USE
EASY TO READ
RELIABLE
RAPID FORMAT
CONVENIENT
MINIMAL SAMPLE MANIPULATION
NO SPECIAL TRAINING NEEDED
NO SPECIAL EQUIPMENT REQUIRED
RESULTS OBTAINED WITHIN 15 MINUTES
Intended for small labs, emergency centres, doctors’ offices, paediatricians, …
Contains the necessary material to easily perform the test: - ten single strips
- ten tubes
- one dilution buffer
- ten sampling systems
- one tube rack
- instructions for use
Uni-Strip Range Uni-Strip Range
Influ-A&B Uni-Strip
Legionella 10 V-TesT
Enteric Range:Enteric Range: Respiratory Range:Respiratory Range:
Rota Uni-Strip
Adeno Uni-Strip
40/41 Adeno Uni-Strip
Crypto Uni-Strip
O157 Coli Uni-Strip
Crypto/Giardia Uni-Strip
Cassette - Methodology Cassette - Methodology
Human Rapid Tests: Enteric Products Human Rapid Tests: Enteric Products
Combi K-SeT > Rapid test to detect both ROTAVIRUS and ADENOVIRUS group A to F in stool (K-1204 & K-1504)
Giardia K-SeT> Rapid test to detect GIARDIA in stool (K-1213 & K-1513)
GastroVir K-SeT> Rapid test to detect both ROTAVIRUS and ADENOVIRUS group F (40/41) in stool (K-1216 & K-1516)
Clostridium K-SeT> Rapid test to detect CLOSTRIDIUM DIFFICILE antigen in human stool samples (K-1220 & K-1520)
Human Rapid Tests: Respiratory Human Rapid Tests: Respiratory Products Products
RSV K-SeT > Rapid test to detect RESPIRATORY SYNCYTIAL VIRUS in nasopharyngeal specimens (K-1206 & K-1506)
Adeno Respi K-SeT > Rapid test to detect RESPIRATORY ADENOVIRUS in nasopharyngeal secretions and/or culture supernatants (K-1209 & K-1509)
Human Rapid Tests: Gastric Products Human Rapid Tests: Gastric Products
Pylori K-SeT > Rapid test to detect HELICOBACTER PYLORI in stool (K-1219 & K-1519)
Human Rapid Tests: Other Human Rapid Tests: Other
HAT Sero K-SeT > Rapid test to detect antibodies specific to TRYPANOSOMA BRUCEI GAMBIENSE in human whole blood, serum or plasma (K-12S2 & K-
15S2)
Enteric ProductsEnteric Products
Combi Combi KK-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
Giardia Giardia KK-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
GastroVir GastroVir KK-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Enteric ProductsEnteric Products
ClostridiumClostridium K K-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Respiratory ProductsRespiratory Products
RSV RSV KK-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Respiratory ProductsRespiratory Products
Adeno Respi Adeno Respi KK--SeT:SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Gastric ProductsGastric Products
PyloriPylori K K-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
OtherOther
HAT SeroHAT Sero K K-SeT:-SeT:
General Information
Product File
Advantages of the kit
Instructions for use
A quick and reliable answer for diagnostic labs
Advantages of cassette kits Advantages of cassette kits
SENSITIVE
SPECIFIC
SIMPLE
EASY TO USE
EASY TO INTERPRET
RELIABLE
RAPID FORMAT
CONVENIENT
MINIMAL SAMPLE MANIPULATION
NO SPECIAL TRAINING NEEDED
NO SPECIAL EQUIPMENT REQUIRED
RESULTS OBTAINED WITHIN 15 MINUTES
ACCURATE: same performances as dipsticks
Coris BioConcept has developed a new legionella antigen detection assay based on colloidal gold nanoparticles with antibodies directed against LPS of L. pneumophila serogroup 1. This proprietary sandwich-type assay, is a ready-to-use test that does not require dilution of urine with a reaction buffer. Liquid sample moves by gravity along the stick within a specific designed device.
Freshly collected urine is simply deposited on the top of the device and result is observed after 15 minutes in the reading window, the upper purple line appearing in case of a positive test. A build-in control is used as migration control (lower purple line).
Methodology Methodology
Gravity Driven Test is a new technology aimed at the development of rapid membrane diagnostic test in urine samples with improved performances such as speed, detectability and safety
Human Rapid Tests: Respiratory Human Rapid Tests: Respiratory Products Products
Legionella V-TesT > Rapid test to detect LEGIONELLA PNEUMOPHILA antigen in urine (C-1815 & C-1915)
Respiratory ProductsRespiratory Products
Legionella Legionella VV-TesT:-TesT:
General Information
Product File
Advantages of the kit
Instructions for use
Legionella 10 V-TesT a quick solution for small laboratories, emergency centres, doctors’ offices, paediatricians, …
A quick and reliable answer for diagnostic labs
OligochromatographyOligochromatography
Oligochromatography is a proprietary technique aimed at the specific detection of amplified products after molecular amplification.
The test is completed without need of specific extra material within 5 minutes.
A positive result means that :
polymerisation process was performed without any inhibitors interference (genuine control probe)
polymerisation process produces amplicons specific for the organism to be detected (specific probe)
Oligochromatography takes advantage of two classical known techniques :
1. Molecular amplification (PCR)
2. Membrane chromatography (MC)
Sid
e A
Sid
e B
Methodology - OligochromatographyMethodology - Oligochromatography
OligoC-TesT consists of a DNA amplification mix and an oligochromatographic strip detecting specifically the pathogen amplified DNA. The ready-to-use PCR mix contains an internal control (IC) template which allows verifying that the PCR occurs properly in each sample tube without any effect of PCR inhibitors.
After PCR, amplified products are allowed to migrate by passive diffusion in the oligochromatographic strip.They hybridize with the target specific and internal control gold-probes, and accumulate on the capture reagent areas. Pink/Purple lines develop at these sites if corresponding amplicons are present. Excess gold-probes hybridize on their complementary sequence at the sites of migration control lines to confirm proper migration.
Oligochromatographic Products Oligochromatographic Products
T.cruzi OligoC-TesT > Rapid Diagnostic of Trypanosoma cruzi by amplification followed by oligochromatographic detection (C-3404)
Leishmania OligoC-TesT > Rapid Diagnostic of Leishmania by amplification and oligochromatographic detection (C-3405)
mex Q-TesT > In vitro mexAB-oprM and meXY-oprM efflux detection in P. aeruginosa by Real Time
PCR (C-3806)
Oligochromatographic ProductsOligochromatographic Products
T.cruzi OligoC-TesT:T.cruzi OligoC-TesT:
Product File
Instructions for use
HIGH SENSITIVITY
HIGH SPECIFICITY
SINGLE SAMPLE ANALYSIS
CARRY-OVER CONTAMINATION PROOF
SAFETY (NO ETHIDIUM BROMIDE)
RAPID
GENUINE PCR INTERNAL CONTROL
QUALITY GUARANTEED PRODUCT
Advantages of the kit:Advantages of the kit:
A quick and reliable answer for diagnostic labs
Oligochromatographic ProductsOligochromatographic Products
Leishmania OligoC-Leishmania OligoC-TesT:TesT:Product File
Instructions for use
HIGH SENSITIVITY
HIGH SPECIFICITY
SINGLE SAMPLE ANALYSIS
CARRY-OVER CONTAMINATION PROOF
SAFETY (NO ETHIDIUM BROMIDE)
RAPID
GENUINE PCR INTERNAL CONTROL
QUALITY GUARANTEED PRODUCT
Advantages of the kit:Advantages of the kit:
A quick and reliable answer for diagnostic labs
Oligochromatographic ProductsOligochromatographic Products
mex Q-TesT:mex Q-TesT:
Product File
Instructions for use
Determination of the status of the efflux pump expression
Two housekeeping genes for standardization
Validation of the PCR product specificity
Relative and absolute quantifications
Certified IVD primers
RNA purity check
PCR efficiency
Advantages of the kit:Advantages of the kit:
A quick and reliable answer for diagnostic labs
Veterinary Rapid Tests Veterinary Rapid Tests
Quatro Vet Uni-Strip > Kit to detect ROTAVIRUS, CRYPTOSPORIDIUM PARVUM, CORONAVIRUS and E. COLI K99 in bovine stool specimen (C-1540)
Surra Sero K-SeT > Rapid test to detect antibodies specific to TRYPANOSOMA EVANSI in animal whole blood or plasma (K-12S1)
Veterinary Rapid Tests Veterinary Rapid Tests
Product File
Instruction for Use
Quatro Vet Uni-Quatro Vet Uni-Strip:Strip:
A quick and reliable answer for diagnostic labs
Veterinary Rapid Tests Veterinary Rapid Tests
Product File
Instruction for Use
Surra Sero Surra Sero KK-SeT:-SeT: A quick and reliable answer for diagnostic labs
http://www.corisbio.com
Thank you for your collaboration and the confidence you place in Coris BioConcept
Coris BioConcept – Science Park CREALYS
Rue Jean Sonet 4A – 5032 Gembloux – BELGIUM
Ph.: +32 (0)81 719 917 – Fax: +32 (0)81 719 919
sales@corisbio.com