Post on 05-Dec-2014
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04/10/23 Lecture 8: BIOMEDICINE 1
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Online bioscience course for grades 6-12
Fall 2009
04/10/23 Lecture 8: BIOMEDICINE 2
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Class mechanics…
• Attend the online Office Hour on Tuesdays at 3 PM via tokbox-Discuss previous week’s video lecture• Online video lecture e-mailed every Wednesday-view lecture and prepare to discuss the following Tuesday• Comment on video lecture using website discussion board• Online Final Exam given 12/16/2009
04/10/23 Lecture 8: BIOMEDICINE 3
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Lecture 8: Biomedicine
04/10/23 Lecture 8: BIOMEDICINE 4
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Biomedical research:
http://www.youtube.com/watch?v=190lGflP1Fs
04/10/23 Lecture 8: BIOMEDICINE 5
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Take Homes:
I. Microbes and diseaseII. Genes and diseaseIII. Medical imagingIV. Pharmaceuticals/BiotechnologyV. Electronic Medical Records
04/10/23 Lecture 8: BIOMEDICINE 6
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Germ theory of disease:
The germ theory of disease, also called the pathogenic theory of medicine, is a theory that proposes that microorganisms are the cause of many diseases. Although highly controversial when first proposed, it is now a cornerstone of modern medicine and clinical microbiology, leading to such important innovations as antibiotics and hygienic practices
http://en.wikipedia.org/wiki/Germ_theory
04/10/23 Lecture 8: BIOMEDICINE 7
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How bacteria cause disease:
http://www.youtube.com/watch?v=0Sx51LC_wcc
04/10/23 Lecture 8: BIOMEDICINE 8
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Antibiotics:
In common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills, or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
Note that antibiotics do not affect viruses…
http://en.wikipedia.org/wiki/Antibiotic
04/10/23 Lecture 8: BIOMEDICINE 9
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Flu attack! How a virus invades your body:
http://www.youtube.com/watch?v=Rpj0emEGShQ
04/10/23 Lecture 8: BIOMEDICINE 10
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Vaccination:
http://www.youtube.com/watch?v=3ykHoIKAtQI
04/10/23 Lecture 8: BIOMEDICINE 11
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MedlinePlus:
MedlinePlus is a free Web site that provides consumer health information for patients, families, and health care providers. MedlinePlus brings together quality information from the United States National Library of Medicine, the National Institutes of Health (NIH), other U.S. government agencies, and health-related organizations. The U.S. National Library of Medicine produces and maintains MedlinePlus.
http://en.wikipedia.org/wiki/MedlinePlus
04/10/23 Lecture 8: BIOMEDICINE 12
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Take Home I
Bacteria and viruses are the causative agents of disease and can be treated by a variety of means, including antibiotics and vaccines…
Microbes and disease
04/10/23 Lecture 8: BIOMEDICINE 13
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Genes and disease:
The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and—when possible—links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene.
http://en.wikipedia.org/wiki/Mendelian_Inheritance_in_Man
04/10/23 Lecture 8: BIOMEDICINE 14
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What are SNPs?:
http://www.youtube.com/watch?v=5raJePXu0OQ
04/10/23 Lecture 8: BIOMEDICINE 15
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23andMe:
https://www.23andme.com
04/10/23 Lecture 8: BIOMEDICINE 16
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What is Cancer:
http://www.youtube.com/watch?v=LEpTTolebqo
04/10/23 Lecture 8: BIOMEDICINE 17
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Oncogenes I:
An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell.
http://en.wikipedia.org/wiki/Oncogene
04/10/23 Lecture 8: BIOMEDICINE 18
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Oncogenes II:
http://www.youtube.com/watch?v=WZdErhuLCtc
04/10/23 Lecture 8: BIOMEDICINE 19
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How a Proto Oncogene Becomes an Oncogene:
http://www.youtube.com/watch?v=2wIVwZksIt4
04/10/23 Lecture 8: BIOMEDICINE 20
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Tumor Suppressors:
http://www.youtube.com/watch?v=iLK3jy-kGvs
04/10/23 Lecture 8: BIOMEDICINE 21
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Metastasis:
http://www.youtube.com/watch?v=rrMq8uA_6iA
04/10/23 Lecture 8: BIOMEDICINE 22
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Take Home II
Some diseases, such as cancer, have as their root causes mutations and variations in genes…
Genes and disease
04/10/23 Lecture 8: BIOMEDICINE 23
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Medical imaging :Medical imaging is the technique and process used to create images of the human body (or parts and function thereof) for clinical purposes (medical procedures seeking to reveal, diagnose or examine disease) or medical science (including the study of normal anatomy and physiology).
As a discipline and in its widest sense, it is part of biological imaging and incorporates radiology (in the wider sense), nuclear medicine, investigative radiological sciences, endoscopy, (medical) thermography, medical photography and microscopy (e.g. for human pathological investigations).
Measurement and recording techniques which are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), Electrocardiography (EKG) and others, but which produce data susceptible to be represented as maps (i.e. containing positional information), can be seen as forms of medical imaging.
http://en.wikipedia.org/wiki/Medical_imaging
04/10/23 Lecture 8: BIOMEDICINE 24
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Medical Imaging presentation:
http://www.youtube.com/watch?v=SF455zziTZI
04/10/23 Lecture 8: BIOMEDICINE 25
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More Than Science Fiction:
http://www.youtube.com/watch?v=wjWHx2qOyOY
04/10/23 Lecture 8: BIOMEDICINE 26
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Take Home III
Medical imaging technologies allow the visualization of medical states of the body and have become a key part of biomedicine…
Medical imaging
04/10/23 Lecture 8: BIOMEDICINE 27
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Pharmaceuticals/Biotechnology:
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease…
http://en.wikipedia.org/wiki/Pharmaceutical_drug
Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use…
http://en.wikipedia.org/wiki/Biotechnology
04/10/23 Lecture 8: BIOMEDICINE 28
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The Biotechnology Age:
http://www.youtube.com/watch?v=He91k5wFYcM
04/10/23 Lecture 8: BIOMEDICINE 29
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Take Home IV
Pharmaceutical and biotechnology based drugs and treatments are the cornerstone of modern biomedicine…
Pharmaceuticals/Biotechnology
04/10/23 Lecture 8: BIOMEDICINE 30
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Electronic medical records:
An electronic medical record is usually a computerized legal medical record created in an organization that delivers care, such as a hospital and doctor's surgery
http://en.wikipedia.org/wiki/Electronic_medical_record
04/10/23 Lecture 8: BIOMEDICINE 31
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IBM Smarter Planet: Electronic Health Records for Evolving Healthcare:
http://www.youtube.com/watch?v=OeaksbGMp8Y
04/10/23 Lecture 8: BIOMEDICINE 32
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Medical records-back to the future:
1961 electronic medical records
http://www.youtube.com/watch?v=t-aiKlIc6uk
04/10/23 Lecture 8: BIOMEDICINE 33
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Take Home V
Electronic Medical Records (EMRs) are an emerging application of information technology in the field of biomedicine…
Electronic Medical Records
04/10/23 Lecture 8: BIOMEDICINE 34
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Next Week:
The ecosystem
An overview of the Earth’s biological systems…
04/10/23 Lecture 8: BIOMEDICINE 35
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instructorMark E Minie PhD
mark@meminie.com