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o  Lesions found a junction of deep cortical gray and subcortical white matter (MS lesions

are periventricular)

o  MRI: increased T2 signal intensity, CSF shows increased opening pressure and

lymphocytes

o  Tx with corticosteroids

- 

Transverse myelitis: acute inflammation of SC that leads to demyelination and spinal cord

dysfunction: AI, viral illness or occur in pt with CT disease

o 

Hours to weeks developmento 

Localized back pain, arm/leg weakness, sensory disturbances (numbness, tingling

burning) and bladder/bowel dysfunction

o 

MRI: spinal cord swelling and T2 signal intensity at affected level

o  CSF shows increased protein and lymphocytes

- 

Brain abscess

o  S aureus: penetrating head wound

o 

Strep

o  Anaerobic: Gram pos cocci, Bacteroides, Fusobacterium, prevotella, actinomyces,

clostridium

o  GN aerobic: enteric rods, proteus, pseudomonas, citrobacter diversus, Haemophilus

o 

Ring enhancing lesions, WBC count normal or increasedo  If organism is unknown: vanc, 3rd generation cepha and Flagyl are given

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