New Progresses of DTI-Map, a New Progresses of DTI-Map, a Program for DTI Computation and Program for DTI Computation and

Fiber TrackingFiber Tracking

Hangyi Jiang, Peter van Zijl, Susumu MoriHangyi Jiang, Peter van Zijl, Susumu Mori

Dept. of RadiologyJohns Hopkins UniversitySchool of Medicine F.M. Kirby Research Center

for Functional Brain Imaging

All-in-One StrategyAll-in-One Strategy

Integrating DTI computation, fiber tracking, 3D visualization, ROI drawing and statistic analysis all together;

Windows-style programming with user-friendly interface, most operations could be done just by few clicks;

Facility in Variety of ScannersFacility in Variety of Scanners

Philips Siemens GE Raw data etc.

Imaging Parameter Dialog

Smart dialogs for parameters input and verification

More options for better visualization or computation efficiency

Gradient table editor are introduced

DTI computation: one-click solution

DTI computation, Color Mapping, Anisotropy analysis, ADC map, fiber tracking etc. can be finished in few minutes just by one click

DTI Computation: tensor matrix

Dyy

Dxx

Dzz

Dxz

Dyz

Dxy

DzyDzx

Dyx

DTI Computation: other-results

Eigen Values Eigen Vectors Color Maps

FA

VR

RA

Primary Axis

2nd Axis

Shortest Axis

x y z

x y z

x y z

Anisotropy

DTI Computation: ADC map

Original Images(Multi-Scans)

ADC Map forevery gradient

Region of Interesting (ROI) Tools

Built-in ROI tools Variety drawing tools, 3D ROI displaying,

ROI combination makes complex-ROI drawing possible

Statistic analysis within ROIs for orthogonal views

ROI file management is available

ROI Tools: Interface

Statistics

Shapes

Operations

Files

Options

ROI Drawing Tools

Rectangle Polygon Ellipse

Multiple-ROI: Multiple Slices ROI (3D ROI):

Slice 120 Slice 121

Slice 123

Slice 124

ROI (Region Of Interesting) drawing tools Different Shape:

Multiple ROIs operations

ROI - A

ROI - B Combination

A + B

A x B

A - B

AND

OR

NOT

OriginalResult

Fiber Tracking

Fiber tracking can be finished in a few minutes

Fiber selection by multi-ROIs combination

Visualization in 2D or 3D views

Fiber data file management is available

Fiber Tracking: Interface

ROI combination

Fiber selection

Fiber color assignment

ROI shape

display options

Fiber-ROI files

Fiber-ROI statistics

File commands

Fiber Tracking: visualization

Selected tracts can be displayed in 3D and 2D orthogonal viewssimultaneously using user assigned color.

Fiber Tracking: visualization

Selected tracts can also be displayed in 2D multi-slices mode.

Fiber Selection: by ROI combination

Fiber can be selected by multi-ROIs combinations such as AND, OR and NOT.This example shows the fibers passing through ROI-A but not ROI-B

ROI - A ROI - B

Fiber Selection: more details

Q: Why do we need it?A: Select (and visualize) the interested fibers within

the whole fiber data record

Intersection (AND) Union (OR)

ROI - AROI - B

ROI - A

ROI - B

Exclusion (NOT)

ROI - AROI - B

A B A B A - B

Fiber Tracking: Algorithm

•Basically, the algorithm is on FACT method (Mori et al, 1999)•Tracking starts when FA > threshold•Tracking stops when FA < threshold or tract changed its direction

sharply

>70ºFA < 0.4

Visualization

Visualizing images in 2D-orthogonal views and 3D view

3D viewing direction changing freely Zoom in, zoom out interactively for 3D view Multi-slices image viewing, image scaling,

image data and profile viewing are available

Visualization: 3D and 2D views

Axial View

Coronal ViewSagittal View

3D View

Visualization: image level adjusting

Image level adjusting helps the users viewing the details more

Visualization: 3D view

3D-visualization:

– Interactively rotating, zooming and so on.– Slice opacity is adjustable– User-defined fiber color

– Synchronized with the 2D orthogonal slice views

Visualization: 3D image opacity

Adjustable image opacity makes see-through possible