Ois general PCP Cryptococcus- Toxoplasma-

10 10 10 10

20 20 20 20

30 30 30 30

40 40 40 40

50 50 50 50

OIs- 10

• OIs are the most common presentation of chronic treated HIV infection

OIs– 10

• No

OIs - 20

• OIs usually present when CD4< 300

OIs – 20

• No usually when CD4 < 200

OIs - 30

• The most common OI in HIV infection

OI – 30

• Oral candidiasis

OI - 40

• Name 2 of the most life threatening OIs

OI– 40

• PCP• Cryptococcosis

OI- 50

• CMV presents when CD4 < 50 and prophylaxis with antivirals should be started

OI– 50

• Antivirals are not part of prophylaxis for HIV related OIs

PCP - 10

• One of the most common causes of death from AIDS in 80s

PCP – 10

• Yes

PCP- 20

• PJP is a common environmental parasite

MHC – 20

• IT is a fungus not a parasite

PCP- 30

• Drug of choice for PCP prophylaxis and alternative if patient has allergy

PCP– 40

• Diagnostic test of choice for PCP

PCP- 40

• Diagnostic test of choice for PCP

PCP– 40

• Sputum DFA for PCP

PCP- 50

• One scenario that patient should stay on prophylaxis for PCP for life

PCP– 50

• If patient had episode of PCP with CD4 > 200

Cryptococcus- 10

• The most common manifestation of cryptococcus infection

Cryptococcus– 10

• CNS infection

Cryptococcus- 20

• Why frequent LPs are needed with crypto meningitis?

Cryptococcus– 20

• Increased ICP

Cryptococcus - 30

• Name two diagnostic tests for Cryptococcus infection

Cryptococcus– 30

• Cryptococcus antigen• Fungal culture

Cryptococcus - 40

• Name the induction therapy for Cryptococcus

Cryptococcus– 40

• Amphotericin + 5FC

Cryptococcus - 50

• This regimen has been used in resource poor countries for treatment of Cryptococcus infection

Cryptococcus– 50

• High doses fluconazole (>800 mg) plus 5FC

Toxoplasma- 10

• Name 2 presentation of toxoplasmosis

Toxoplasma- – 10

• Fever, headaches, seizures, no clinical manifestations

Toxoplasma - 20

• A common carrier of toxoplasma (animal)

Toxoplasma– 20

• Cat

Toxoplasma - 30

• The antibiotic that is used for prophylaxis for Toxoplasma is also effective for other OIs

Toxoplasma– 30

• Bactrim is also effective against PCP

Toxoplasma- 40

• Name alternative antibiotics for Toxoplasma (if there is allergy to the drug of choice)

Toxoplasma– 40

• Clindamycin, pyrimethamine

Toxoplasma- 50

• Duration of prophylaxis for toxoplasma

Toxoplasma- 50

• Discontinue ppx when CD4>200 > 3 months