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CURRICULUM VITAE
OLGA KLEPITSKAYA, M.D.
Academic Address: Clinic Address
University of Colorado Denver University of Colorado Hospital
Academic Office 1, Mr. 5219 1635 Aurora Ct.
12631 East 17th Avenue, Box B185 4
th Floor, Neurology
Aurora, CO 80045 Aurora, CO 80045
Phone: (303) 724-2210 Phone: (720) 848-2080
Fax: (303) 724-2212 Fax: (720) 848-2106
Research Affiliation: Veteran Administration Hospital
Clinical Translational 1055 Clermont Street
Research Center Denver, CO 80220
12401 E 17th Ave, B141, Phone: (303) 393-2874
Aurora, CO 80045 Fax: (303) 393-4648
1. Education:
1973-1983 School #5, Khabarovsk, Russia, graduated with Gold Medal, GPA 5.00 of 5.00
1983-1989 Far Eastern State Medical University (Khabarovsk State Medical
Institute), Khabarovsk, Russia, GPA 5.00 of 5.00, graduated with Honors,
1989-1996 Neurology Residency, Far Eastern State Medical University, Khabarovsk, Russia
1996 Neurophysiology Fellowship, Far Eastern State Medical University, Khabarovsk
2001-2002 Internal Medicine Internship, Resurrection Medical Center, Westlake Hospital
Melrose Park, Illinois
2002-2005 Neurology Residency, University of Colorado Denver (UCD), Aurora, Colorado
2005-2006 Movement Disorders Fellowship, Stanford University Medical Center, Stanford,
California
2. Academic Appointments:
1990-1992 Instructor in Neurology, Department of Speech Disorders and Therapy, Far
Eastern State Pedagogical University, Khabarovsk, Russia
1990-1992 Instructor in Neurology, Department of Neurology, Far Eastern State Medical
University, Khabarovsk, Russia
1994-1998 Instructor in Neurophysiology, Department of Continued Medical Education,
Far Eastern State Medical University, Khabarovsk, Russia
2006-2008 Clinical Instructor, Department of Neurology, University of Colorado Denver,
Aurora, CO
2008-Present Assistant Professor, Department of Neurology, University of Colorado Denver,
Aurora, CO
3. Hospital, government or other professional positions:
1989-1990 Research Associate, Central Research Laboratory, Far Eastern State Medical
University, Khabarovsk, Russia
1989-1996 Teaching Assistant, Department of Neurology, Far Eastern State Medical
University, Khabarovsk, Russia
1992-1994 Director of Public Relations Department, Far Eastern Association of Medical
Workers, Khabarovsk, Russia
1992-1994 Medical Journalist and Editor, Far Eastern TV/Radio Station, Khabarovsk,
Russia
1994-1998 Attending Neurologist, Department of Neurology, Regional Hospital #1,
Khabarovsk, Russia
1996-1998 Director, Electroencephalography Laboratory, Department of Neurodiagnositcs,
Regional Hospital #1, Khabarovsk, Russia
1996-1998 Neurophysiologist, Department of Neurodiagnostics, Regional Hospital #1,
Khabarovsk, Russia
1998-1999 Research Assistant, Department of Neuroscience, Sleep Laboratory,
Washington State University, Pullman, Washington
1999-2001 Medical and Social Interpreter, Social and Health Services, State of Washington,
Spokane, Washington
2000 Medical Consultant, Ukrainian-American Educational Project, Washington
State University, Pullman, Washington
2000-2001 Electroencephalography Technician, Gritman Medical Center, Moscow, Idaho
2006 – present Attending Neurologist, University of Colorado Hospital, Aurora, Colorado
2007-2008 Attending Neurologist, The Children’s Hospital, Aurora, Colorado
2007-present Staff Neurologist, Veterans Administration Hospital, Denver, Colorado
4. Honors, Special Recognitions, and Awards:
1983 Gold Medal for Excellence, High School # 5, Khabarovsk, Russia
1983 First Place Award of All-Russian Academic Olympiad in Chemistry
1985-1989 Federal Highest Individual Scholarship, named by V.I. Lenin, Far Eastern State
Medical University, Khabarovsk, Russia
1989 Graduated with Honors, Far Eastern State Medical University, Khabarovsk,
Russia
2011 Research Abstract Selected by Faculty 1000 as a “Particularly Important
Development in the Field” at the 10th International Congress on Alzheimer’s and
Parkinson Diseases at http://f1000.com/about/whatis
2011 Scholarship from the American Neurological Association for the Translational
and Clinical Research Course for Clinician, Scientists, Baltimore, Maryland
(declined attendance)
2011 “Doctor of the Month,” University Physician’s Incorporated CU Doctors
Website http://www.cudoctors.com/find-a-doctor/?keywords=olga%20klepitskaya
2011 Scholarship from the National Institute of Health for the National Institute of
Neurological Disorders and Stroke (NINDS) Clinical Trial Methods Course
(CTMC), Vail, Colorado (declined attendance).
2012 Leadership Development Scholarship from the American Academy of Neurology
for the Course in Leading Others, New Orleans, Louisiana
2012 Scholarship from the National Institute of Health for the National Institute of
Neurological Disorders and Stroke (NINDS) Clinical Trial Methods Course
(CTMC), Vail, Colorado
2012 Best Doctors in America 2013 database, selected by peers
2012 Best Doctors for executives, selected by Colorado Biz magazine
2013 Listed in Guide to America’s Top Physicians by SLD Industries, Inc.
5. Professional Organizations and Affiliations:
1999-indefinite Russian Association of Neurologists and Neurosurgeons
2003-present American Academy of Neurology (AAN)
2006-present Movement Disorders Society (MDS)
2006-2007 International Society of History of Neurology
2006-present Parkinson Association of the Rockies (PAR)
2007-present Parkinson Study Group (PSG) – membership by credentialing
2006-present Colorado Society of Clinical Neurology
2013-present American Neurological Association (ANA)
6. Major Committee and Service Responsibilities:
University of Colorado School of Medicine: o 2008-present Co-Director, University of Colorado Hospital Deep Brain Stimulation
Program o 2012 “Hearts of All Ages” fundraising event organization committee
Denver Veteran Administration Hospital:
o 2007-present Director, Eastern Colorado satellite of Parkinson Disease Research,
Education and Clinical Center (PADRECC)
7. Licensure and Board Certification:
1996-indefinite Medical Doctor-Neurologist, Government of Russian Federation,
Ministry of Healthcare, Far Eastern Office
1998-2008 Medical Doctor-Neurologist of the First Qualification Level,
Government of Russian Federation, Ministry of Healthcare, Far Eastern
Office
1999-indefinite Medical and Social Interpreter (English- Russian), Department of Social
and Health Care Services, State of Washington
2001-2002 State of Illinois – Physician Training License
2002-2005 State of Colorado – Physician Training License
2005-2007 State of California – Physician and Surgeon License
2006-present State of Colorado – Medical License
2008-2018 Diplomat of American Board of Psychiatry and Neurology
8. Review and Referee Work:
Ad Hoc:Reviewer: o American Journal of Speech Language Pathology o Cephalgia
Editorial Board Member:
o Brain Disorders and Therapy
9. Invited Lectures and Presentations:
Local: o Klepitskaya O. Tick-Born Encephalitis: What can we Learn from it About the West Nile
Virus Infection? Neurology Grand Rounds, UCD, March 2005.
o Klepitskaya O. Deep Brain Stimulation: Past, Present, and Future. Neurology Grand
Rounds, UCD, April 2007.
o Klepitskaya O. Parkinsonism, Misinterpreted as Status Epilepticus. Neurology Grand
Rounds, UCD, October 2007.
o Klepitskaya O. Neurosurgery for Parkinson Disease beyond DBS. Neurology Grand
Rounds, UCD, August 2009.
o Klepitskaya O. Neurosurgery for Parkinson Disease. Neurosurgery Grand Rounds,
UCD, March 2009.
o Grier L, Hoyt B, Klepitskaya O. Psychiatric Considerations in Deep Brain Stimulation
Surgery for Parkinson Disease. Psychiatry Grand Rounds, UCD, April 2009.
o Klepitskaya O. Dopamine Dysregulation Syndrome. Neurology Grand Rounds, UCD,
March 2011.
o Klepitskaya O. Update on Neurosurgery for Parkinson Disease. Neurosciences Seminar,
Denver, CO, April 2011.
o Klepitskaya O. Deep Brain Stimulation for Early Parkinson Disease. Neurology Grand
Rounds, UCD, July 2012.
o Leehey M, Hedeman J, Klepitskaya O, et al. Medication Adherence in Parkinson
Disease. Quality Improvement Report. Neurology Grand Rounds, University of Colorado
Denver, May 2013.
Regional: o Klepitskaya O. Deep Brain Stimulation: Past, Present, and Future. Colorado Society of
Clinical Neurology, Denver, CO, April 2007.
o Klepitskaya O. Deep Brain Stimulation: Past, Present, and Future. 20th Annual
Conference, ‘Neurosurgery of the Rockies,’ Vail, CO, February 2007.
o Klepitskaya O. Neurosurgery for Parkinson Disease Beyond DBS. 22nd
Annual
Conference, ‘Neurosurgery of the Rockies,’ Beaver Creek, CO, February 2009.
o Klepitskaya O. Update on Neurosurgery for Parkinson Disease. Colorado Society of
Clinical Neurology, Denver, CO, November 2010.
o Klepitskaya O. Deep Brain Stimulation for Early Parkinson Disease. 25th Annual
Conference, ‘Neurosurgery of the Rockies,’ Beaver Creek, CO, February 2012.
o Klepitskaya O. Programming of Deep Brain Stimulation for Parkinson disease.
Practical clues and Case Presentations. Regional DBS Programming Workshop.
December 2012, Denver, CO. 19 attendees
National: o Klepitskaya O. Tick-Born Encephalitis: What can we learn from it about the West Nile
Virus Infection? Department of Neurology, Stanford University, December 2005.
o Klepitskaya O. Parkinsonism, Misinterpreted as Status Epilepticus. Department of
Neurology, Stanford University, May 2006.
o Klepitskaya O. Primary Dystonia Misdiagnosed as Parkinson Disease. National VA
Parkinson Disease Consortium Meeting, San Francisco, CA, September 2010.
o Klepitskaya O. Deep Brain Stimulation: Patient Selection Workshop. National DBS
Forum, San Francisco, CA, October 2011.
o Klepitskaya O. Deep Brain Stimulation for Early Parkinson Disease, invited lecture,
Banner Sun Health Research Institute, Phoenix, AZ, April 2012.
International: o Klepitskaya O. Response of the Subthalamic Nucleus Neurons to Vocalization. 1
st
international symposium, “Basal Ganglia Speech Disorders and Deep Brain Stimulation.”
London, England, July 2007.
10. Teaching Record
Presentations to Medical Students:
2009 Phenomenology of Movement Disorders, 2nd
year medical students core curriculum.
2010 Phenomenology of Movement Disorders, 2nd
year medical students core curriculum.
2011 Phenomenology of Movement Disorders, 2nd
year medical students core curriculum.
Presentations to Residents:
September, 2007 Deep Brain Stimulation, Physical Medicine and Rehabilitation Residents
August, 2008 Deep Brain Stimulation, Neurology Residents
May, 2009 Psychogenic Movement Disorders and Tardive Syndromes, Neurology
Residents
October, 2009 Dystonia, Neurology Residents
Psychogenic Movement Disorders, Neurology Residents
January, 2010 Overview of Movement Disorders, Family Medicine Residency program
February, 2010 Deep Brain Stimulation, Neurology Residents
January, 2011 Overview of Movement Disorders, Family Medicine Residency program
January, 2012 Psychogenic Movement Disorders, Neurology Residents
Surgical treatment of Movement Disorders, Neurology Residents
January, 2012 Overview of Movement Disorders, Family Medicine Residency program
September, 2012 Surgical treatment of Movement Disorders, Neurology Residents
September, 2013 Surgical treatment of Movement Disorders, Neurology Residents
Teaching CME courses:
September, 2009 Pharmacological Treatment of Parkinson disease. UCD CME
course, “Advances in Parkinson Disease and Multiple sclerosis,”
Denver CO
July, 2010 Advances in treatment of Movement disorders. St. Mary Hospital,
Grand Junction, CO
April, 2009 Deep Brain Stimulation. Continued Nursing Education course,
Aurora Colorado
September, 2012 Surgical Treatment of Parkinson disease. UCD CME course,
“Advances in Parkinson Disease and Multiple sclerosis,”
Denver CO
September, 2013 Treatment of Tremor. UCD CME course, “Movement Disorders
and Epilepsy,” Denver CO
Ward/Clinic Attending Duties:
2006-present Supervision and bedside teaching of medical students, pharmacy
students, Neurology and Internal Medicine residents, and Movement
disorders Fellow . UCH Movement Disorders Clinic. 16 hours/week
average.
2006-present Teaching and training of Movement Disorders fellows, physician
assistants, and nurse practitioners in subcortical mapping with
microelectrode recording for Deep Brain Stimulation (DBS)
implantation, UCH Operative Room, 8 hours/week average.
2006-present Teaching and training of movement disorders fellows, nurse
practitioners, and physician assistants in DBS programming, UCH
Movement Disorders Clinic. 16 hours/week average.
2006-present Teaching and training of movement disorders fellows, and neurology
residents in botulinum toxin.
2008- 2010 Attending on inpatient Neurology ward, and bedside teaching medical
students and neurology residents, UCH – 4-6 weeks per year.
Research mentorship:
Movement Disorders Fellows:
o Heather Ene, 2007-2009
Project title: “The effect of yoga on quality of life in Parkinson disease patients, and Gait
and balance outcome after DBS for Parkinson disease.”
o Aaron Haug, 2011-2012
Project title: “Number of microelectrode recording passes during bilateral staged vs.
unstaged deep-brain stimulation surgery for Parkinson's disease.”
Neurology Residents:
o Christy Young, 2009- 2010
Project title: Residency graduation project: Possibility of disease modifying effect of
Deep Brian Stimulation.
o Andreas Muchas- Martin, 2012 – Current.
Project Title: Possibility of disease modifying effect of Deep Brian Stimulation.
o Drew Kern, 2011 – 2012.
Project title: An Objective Double-Blind Evaluation of Bupropion and Citalopram in an
Individual with Friedreich Ataxia. Medical Students:
o Kathleen Reid, 2008-2009.
Project title: Prevalence of dopamine dysregulation syndrome in Parkinson’s disease
patients-candidates for Deep Brain Stimulation.
o John Fowler, 2008-2010.
Project title: Number of microelectrode recording passes during bilateral staged vs.
unstaged deep-brain stimulation surgery for Parkinson's disease.
o Tyson Oberdorfer, 2011- 2012.
Project title: “Microvascular white matter disease as a predictive factors for cognitive
outcome after bilateral Subthalamic Nucleus Deep Brain Stimulation for Parkinson
Disease.”
o Tam Nguen, 2011-2012.
Project title: Primary Dystonia Misdiagnosed as Parkinson Disease.
o Alexander Neuwelt, 2012 .
Project title: Primary Dystonia Misdiagnosed as Parkinson Disease.
o Thomas Ragole, 2012-Current.
Project title: Disease modifying effect of Deep Brain Stimulation.
Patient Outreach and Education:
Treatment of Essential Tremor: International Essential Tremor Foundation, patient education
seminar, September 2007, Colorado Springs, CO, 70 attendees
Deep Brain Stimulation for Parkinson’s disease: Parkinson Association of the Rockies (PAR),
October 2007, Denver, CO, 70 attendees
PD 101: Parkinson Association of the Rockies (PAR), October 2008, Denver, CO, 30 attendees
Treatment of Essential Tremor: International Essential Tremor Foundation patient education
seminar, October 2009, Denver CO, 200 attendees
DBS for Parkinson disease: Davis Phinney Foundation, Victory Summit, October 2009,
Westminster CO, 200 attendees
Neurologists speak about Yoga therapy: Publication in “Yoga Therapy Today,” Journal by, The
International Association of Yoga Therapists, March 2009; 5(1):8
Deep Brain Stimulation: Parkinson Support Group, June 2010, Pueblo, CO, 30 attendees
Deep Brain Stimulation for Dystonia: Dystonia Support Group, June, 2010, 25 attendeed.
Deep Brain Stimulation for Movement Disorders: Patient Symposium, July 2010, Grand
Junction, CO, 300 attendees
Deep Brain Stimulation: University of Colorado patient education Symposium, November 2010
Deep Brain Stimulation. Patient education Symposium, July 2011, Basalt, CO
Deep Brain Stimulation: Parkinson’s Association of the Rockies, “Doctor is In”: November, 2011,
Colorado Springs, CO, 100 attendees; and February 2012, Loveland, CO, 45 attendees
Deep Brain Stimulation for Movement Disorders: Parkinson Support Group, July 2012, Edwards,
CO, 15 attendees
DBS for Parkinson disease: Davis Phinney Foundation, Victory Summit, November 2012,
Denver CO, 400 attendees
Physicians Outreach and Education:
Visiting lectures to local physicians’ offices with discussions regarding patients’ selection,
outcomes and referral process to Deep Brain Stimulation surgery:
Kaiser Permanente Neurology Group, Denver, CO
Drs. London, Nitka, Renkin, Ament, Smith. Lakewood, CO
Drs. Zacaryas and Miller, Boulder, CO
Drs. Redosh, Seibert, Wheatridge, CO
Drs. Poiscne, Fedor, Thornton, CO
Drs. Sunku, Rawat, Smith, Cohen, Pueblo, CO
Drs. Shaffer, Kerber, Cheyenne, WY
Drs. Lopresti, Himes, Ball; Scottsbluff, NE
Drs. Schmitt, Jacobs, Loveland, CO
Dr. Siegel; Greeley, CO
Drs. Round, Ginsburg, Stambuck, McNutt, Denver. CO
Drs. Dean, Burnbaum, Gilman; Grand Junction, CO
DR. Gipson, Edwards, CO
Public Relations and Marketing:
Deep Brain Stimulation eases Parkinson’s: Denver Post, and Colorado Channel 4 News, May
2008, Denver, CO
Her Colors flying: Denver Post, January 2009, Denver, CO
Deep Brain Stimulation for Movement Disorders: report from the Patient Symposium, July 2010,
Grand Junction, CO, featured on Grand Junction Channel 11 News
“7 Everyday Hero” Award Presentation to DBS patient and family liaisons and DBS patients’
support group coordinators Valerie Graham and Kate Kelsall, featured on Colorado Channel 7
News.
Yoga Used to Treat Parkinson’s Disease: Channel 7 News, August 2010, Denver, CO
Overview of Movements Disorders. Presentation to UCH Foundation guests and community
leaders, February and March 2012
Research and Scholarly activities:
Sponsored research and clinical trials:
NIH NIDCD 9/07-9/12
Lorraine Ramig, PhD, CCC-SLP (PI) Total Award: N/A
“Intensive Voice Treatment (LSVT®LOUD) for Parkinson’s Disease Following Deep Brain Stimulation
of the Subthalamic Nucleus”
Role: Consultant
Solstice Neurosciences, Inc. 9/07-9/10
Eric Papert, MD (PI) Total Award: $91,981
“A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Single Treatment, Sequential Dose-
Escalation, Safety, Tolerability and Preliminary Efficacy Study of MYOBLOC ® for the Treatment of
Troublesome Sialorrhea in Parkinson’s Disease Patients”
Role: Primary Investigator
UCB Biosciences, Inc. 3/08-2/12
Whitesides, J. (PI) Total Award: $266,994
“Multi-Center, Randomized, Double-Blind, Placebo-Controlled, 5-Arm, Parallel-Group Trial to assess
Rotigotine Transdermal System Dose Response in Subjects with Advanced-Stage Parkinson Disease”
Role: Co-Investigator
Neurologix, Inc. 6/08-6/14
During, M. (PI) Total Award: $1,237,580
“Phase 2 Safety and Efficacy Study Evaluating Glutamic Acid Decarboxylase Gene Transfer to the
Subthalamic Nuclei in Subjects with Advanced Parkinson Disease”
Role: Neurophysiologist
Alzheimer’s Association 9/09 - Current
Victoria Pelak, MD (PI) Total Award: N/A
“Visuospatial Assessment of Virtual 3D Radial Optic Flow Illusion in Healthy Aging, Mild Alzheimer’s
Disease and Pre- and Post- Deep-Brain Stimulation (DBS) Parkinson’s Disease Subjects”
Role: Co-Investigator
Pico-Tesla Magnetic Therapies 4/09-11/11
Olga Klepitskaya, MD (PI) Total Award: $248,105
“Randomized, Double-Blind, Sham-Stimulation Controlled Study of the Application of Magnetic Fields
Using the Resonator Device for the Treatment of Parkinson Disease”
Role: Primary Investigator
IMPAX Pharmaceuticals 3/10-12/11
Olga Klepitskaya, MD (PI for UCD) Total Award: $254,255
“Study to Evaluate the Safety and Efficacy of IPX066 in Advanced Parkinson Disease”
Role: Primary Investigator
Tercica, Inc. (A Subsidiary of the IPSEN Group) 8/11-7/14 Current
Wes Cetnarowski, MD (PI for UCD) Total Award: $78,795
“DYSPORT ™ for Injection Abobotulinumtoxin A Neurotoxin Clinical and Health Economics Outcomes
Registry in Cervical Dystonia (ANCHOR – CD)”
Role: Primary Investigator
Biotie 12/11-12/14
Dr. Stephen Bandak, MB BS MRCP (PI) Total Award: $241,285
“A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of SYN115 as
Adjunctive Therapy in Levodopa-Treated Parkinson’s Subjects with End of Dose Wearing off”
Role: Primary Investigator
Sponsor : NIH-NINDS 1/13 - Current
Cirys Zabetian, PhD (PI) Total Award: $260,000
“PAGER: Parkinson”s Genetic Research Study”
Role: Primary Investigator
Solstice Neurosciences, LLC a subsidiary of US World Meds, LLC.
Olga Klepitskaya, MD (PI for UCD)
“A Phase 3, Multicenter, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study
of MYOBLOC® (Part A) Followed by Open-Label, Multiple-Treatment with MYOBLOC® (Part B) in
the Treatment of Troublesome Sialorrhea in Adult Subjects”
Role: Primary Investigator
Ipsen Biopharmaceuticals, Inc.
Olga Klepitskaya, MD (PI for UCD)
“A Phase IIIb, Multicentre, Randomised, Double-Blind, Placebo-Controlled Study Evaluating the
Efficacy and Safety of DYSPORT Using 2 mL Dilution in Adults with Cervical Dystonia”
Role: Primary Investigator
Ipsen Biopharmaceuticals, Inc.
Olga Klepitskaya, MD (PI for UCD)
“A Phase IIIb, Prespective, Multicentre, Open-Label Extension Study to Assess Long Term Safety and
Effectiveness of DYSPORT Using 2mL Dilution in Adults with Cervical Dystonia”
Role: Primary Investigator
Research Grants:
Boedecker Foundation Parkinson Research Grant. 2009-2011
Donated to the UCD Movement Disorders group for Parkinson Disease related research in honor
of Julie Berardi, Deep Brain Stimulation patient.
Total award $200,000
Investigator Initiated Research:
Sponsor N/A 1/06 – 12/07
Ojemann, MD (PI) Total Award – N/A
Response of the Subthalamic Nulcleus Neurons to Vocalization
Role Co- Investigator
Sponsor N/A 1/08- 5/09
Olga Klepitskaya, MD (PI) Total Award: N/A
“Three-Dimensional Computerized Model of Human Basal Ganglia for Microelectrode Recording During
Deep Brain Stimulation Surgery”
Role: Primary Investigator
Sponsor N/A 1/08- 5/09
Ojemann, MD (PI) Total Award: N/A
Development of Mock microelectrode recording software for sham surgery controlled clinical trials of
surgical treatments for Parkinson’s disease
Role: Co-Investigator
Boedecker Foundation Parkinson Research Grant 12/09-12/11
Benzi Kluger, MD, MS (PI) Total Award: $200.000
“Magnetoencephalography (MEG) and Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD)”
Role: Co-Investigator
Boedecker Foundation Parkinson Research Grant 12/09-12/11
Olga Klepitskaya, MD (PI) Total award: $200.000
“Gait and balance outcomes after bilateral Subthalmic Nucleus Deep Brain Stimulation surgery for
Parkinson disease”
Role: Primary Investigator
Boedecker Foundation Parkinson Research Grant 12/09-12/11
Olga Klepitskaya, MD (PI) Total award: $200.000
Number of microelectrode recording passes during bilateral staged vs. unstaged deep-brain stimulation
surgery for Parkinson's disease.
Role: Primary Investigator
Boedecker Foundation Parkinson Research Grant 12/09-12/11
Olga Klepitskaya, MD (PI) Total award: $200.000
Prevalence of dopamine dysregulation syndrome in Parkinson’s disease patients-candidates for deep
brain stimulation
Role: Primary Investigator
Boedecker Foundation Parkinson Research Grant 12/09-12/11
Olga Klepitskaya, MD (PI) Total award: $200.000
“Predictive Factors for Cognitive Outcome after Bilateral Subthalamic Nucleus Deep Brain Stimulation
for Parkinson Disease”
Role: Primary Investigator
Sponsor N/A 9/12 - Current
Olga Klepitskaya, MD (PI) Total Award: N/A
“An Objective Double-Blind Evaluation of Bupropion and Citalopram in an Individual with Friedreich
Ataxia”
Role: Primary Investigator
Bibliography:
Peer-reviewed Articles: 1. Klepitskaya OS. Shishmakov, YV. Biological Activity of Pine-Tree Oil. Questions of the
Ecological Biochemistry and Physiology;1988: 45-49 Article in Russian
2. Klepitskaya OS, Ottieva EN. Neurological Disorders in Patients with Lupus Erythematosus.
Far Eastern Medical Journal;1998(2):67-68 Article in Russian
3. Klepitskaya OS, Rykova MG. Modern Clinical Variations of Conversion Disorder. Topics in
Psychopathology. Publication of the Russian Institute of Mental Diseases named after
Serbskiy;1998:22-28 Article in Russian
4. Goetz, C.G., Tilley, B.C., Shaftman, S.R…. Klepitskaya, O….et. al. Movement Disorder
Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS):
Scale presentation and clinimetric testing results. Movement Disorders. 2008; 23 (15): 2129 -
2170
5. Kluger BM, Klepitskaya O, Okun MS. Surgical Treatment of Movement Disorders. Neurologic
Clinics of North America; 2009:633-677
6. Patel SG, Stickrath CR, Anderson M, Klepitskaya O. How Should Parkinson’s Disease be
Managed Perioperatively? The Hospitalist. 2010;15(6):19-22
http://www.thehospitalist.org/details/article/704937/How_should_Parkinsons_disease_be_mana
ged_perioperatively.html
7. Spielman J, Mahler L, Halpern, A., Gilley P, Klepitskaya O, Ramig L. Intensive Voice
Treatment (LSVT®LOUD) for Parkinson's disease following Deep Brain Stimulation of the
Subthalamic Nucleus. Journal of Communication Disorders. 2011;
doi:10.1016/j.jcomdis.2010.05.003
8. Klepitskaya OS, Cole W, Henderson J, Bronte-Stewart H. Deep Brain Stimulation in “On”-
Parkinson Hyperpyrexia. Neurology. 2011;76(7): s69-s71
9. Hall D, Klepitskaya O, Leehey M. Fragile X-Associated Tremor Ataxia Syndrome in FMR1
Gray Zone Allele Carriers. Movement Disorders. 2011;27(2):297-301
10. Klepitskaya O, Neuwelt AJ, Nguyen TM, Leehey M. Primary Dystonia Misinterpreted as
Parkinson Disease: A Case Presentation and Practical Clues. Neurology. (In Press, October 2013.)
Book Chapters:
1. Klepitskaya O. Parkinsonism- Hyperpyrexia syndrome. In: Kompoliti K, and Verhagen Metman
L (eds.) Encyclopedia of Movement disorders. 2010; vol. 1, pp. 399-401 Oxford: Academic Press.
2. Klepitskaya O. Dopamine Dysregulation syndrome. In: Kompoliti K, and Verhagen Metman L.
(eds.) Encyclopedia of Movement disorders. 2010; vol. 1, pp. 323-326 Oxford: Academic Press.
3. Berk J, Klepitskaya O. Thalamotomy. In: Mechanisms and emerging therapies of tremor
disorders. New York: Springer; 2013(24):431-461
4. Klepitskaya O. Restless Leg Syndrome. In: Barton B and Hall D (eds.) Non-Parkinsonian
Movement Disorders. 2013; Oxford: Wiley-Blackwell (in print)
Scientific Abstracts and Poster Presentations (competitive):
1. Klepitskaya OS, Maa EH, Tyler KL. Delayed Seroconversion in Immunocompromised Patient
with West Nile Virus-Associated Brainstem Encephalitis. 57th Annual Meeting of the American
Academy of Neurology, April 2005, Miami, Fl, USA
2. Klepitskaya OS, Proskokova TN. Hepatolenticular Degeneration: Wilson- Konovalov’s Disease.
58th Annual Meeting of the American Academy of Neurology, April 2006, San Diego, CA, USA
Neurology;2006(66):A2
3. Grenier Y, Spielman JL, Klepitskaya OS, Ramig LO, Henderson JM, Bronte-Stewart HM.
Methodology for objective motor speech assessment outcome after deep brain stimulation for
Parkinson’s disease. 10th International Movement Disorders Congress, Kyoto, Japan, October
2006 Movement Disorders;2006(21):S655
4. Klepitskaya OS, Cole WL, Bronte-Stewart HM Evolution of Parkinson disease during 4 years
of Deep Brain Stimulation: a case report. 10th International Movement Disorders Congress,
Kyoto, Japan, October, 2006 Movement Disorders;2006(21):S665
5. Klepitskaya OS, Fischbein NJ, Hall DA, Bronte-Stewart HM. Superficial Siderosis with
supranuclear palsy, parkinsonism and falls. 10th International Movement Disorders Congress,
Kyoto, Japan, October, 2006 Movement Disorders;2006(21):S525- S526
6. Klepitskaya OS, Cole WL, Henderson JM, Bronte-Stewart HM. Deep brain stimulation
decreases the risks for Parkinsonism-Hyperpyrexia syndrome and suppresses levodopa-induced
dyskinesias: a case report. 10th
International Movement Disorders Congress, Kyoto, Japan,
October, 2006.Movement Disorders;2006(21):S666-S667 and Annual meeting of Parkinson
Study Group, Chicago IL, USA, 2006 Movement Disorders;2006(21):1552
7. Richardson MS, Ojemann SG, Klepitskaya OS. Response of the subthalamic nulcleus neurons
to vocalization. 11th
International Movement Disorders Congress, Istanbul, Turkey, June
2007.Movement Disorders;2007(22):S53 and 1st international symposium “Basal ganglia speech
disorders and Deep Brain Stimulation,” July 2007, London, UK
8. Klepitskaya OS, Kim Z, Richardson MD, Ojemann SG. Three-dimensional computerized
model of subthalamic nucleus. 12th
International Movement Disorders Congress, Chicago, IL,
USA, June 2008.Movement Disorders;2008(23):S108 – Poster was selected for guided poster
tour
9. Klepitskaya O, Kumar R. Efficacy and Safety of Low Level Electromagnetic Fields Treatment
in Parkinson’s Disease. Annual meeting of Parkinson’s Study Group, Salt Lake City, UT, USA.
Movement Disorders;2008(11):1633
10. Klepitskaya OS, Fowler JJ, Kluger BM, Ojemann SG. Number of microelectrode recording
passes during bilateral staged vs. unstaged deep-brain stimulation surgery for Parkinson's disease.
13th International Movement Disorders Congress, Paris, France, June 2009. Movement
Disorders;2009(24):S485-S486
11. Klepitskaya OS, Koop MM, Bronte-Stewart HM. Longitudinal study of Microlesion Effect on
Bradykinesia after Subthalamic Nucleus Deep Brain Stimulation Surgery for Parkinson's disease.
13th International Movement Disorders Congress, Paris, France, June 2009 Movement
Disorders;2009(24):S485
12. Reid KA, Hoyt B, Tanabe J, Ojemann SG, Legenska A, Klepitskaya OS. Prevalence of
dopamine dysregulation syndrome in Parkinson’s disease patients-candidates for deep brain
stimulation. 14th
International Movement Disorders Congress, Buenos Aires, Argentina, June
2010 Movement Disorders;2010(25):S282
13. Klepitskaya OS, Hoyt B, Berk JJ, Ojemann SG. Reversible cognitive impairment induced by
deep brain stimulation of subthalamic nucleus. 14th
International Movement Disorders Congress,
Buenos Aires, Argentina, June 2010 Movement Disorders;2010(25):S446
14. Pelak VS, Choi M, Jung S, Halliday B, Hager E, Klepitskaya O, Ojemann S, Filley C, Dubin M.
“Visuospatial Assessment By Virtual 3D Radial Optic Flow Illusion In Healthy Aging, Mild
Alzheimer’s Disease (AD), And Pre-Deep-Brain Stimulation (DBS) Parkinson’s Disease (PD)
Subjects.” Abstract A-316-0002-01523. 10th Annual International Conference on Alzheimer’s
and Parkinson’s Disease. Barcelona, Spain. March 9-13th, 2011
15. Hall D, Klepitskaya OS, Tassone F, Spector E, Leehey M. FXTAS in Patients with Fragile X
Gray Zone Alleles. 63rd
Annual AAN Meeting, Honolulu, Hawaii, March 2011. Neurology;
2011(76)9:SA399
16. O.S. Klepitskaya, Z. Kim, S.G. Ojemann. Mock microelectrode recording is undistinguishable
from a real time recording in sham surgery controlled clinical trial of new surgical treatment for
Parkinson’s disease [Abstract 221]. Movement Disorders; 2011;26(Suppl 2): page S73
17. Ragole T, Michas-Martin A, Moss A, Juarez-Colunga E, Klepitskaya O. “Review of published
outcomes of subthalamic nucleus deep brain stimulation in Parkinson disease supports hypothesis
of disease-modifying effect.” 2013 Movement Disorders;2013(25):1316, 25th
Annual meeting of
Parkinson’s Study Group & 27th
Annual PSG Symposium, Montreal, Canada.