Develop a bone-integration method topermanently implant limb prosthesis

By Lokesh Patil

Introduction

• 1.7 million people with limb loss in US• Types of available lower limb prosthesis Limitations of socket type prosthesis - Skin irritations -Bone deterioration -Soft tissue damage -Need for refitting

Contd..

Osseointegration

• What is Osseointegration• Different stages of osseointegration• Factors affecting osseointegration

Titanium properties

Current bone-integration methods

• Two stages of surgeries performed Stage 1- Implant is fixed in medullary cavity Stage 2: Abutment fixed after 6 months

Advantages of bone-anchored prosthesis

• Lower feeling of weight• More and precise control over prosthesis• No pain, perspiration and soft tissue damage• No need for socket replacement• Easy donning and doffing• Osseoperception

Disadvantages

• Two surgeries needed at gap of around six months

• Relatively long Rehabilitation time• High risk of deep-infection• Chances of loosening of implant from the

bone

Proposed design

• Using a grid blasted ribbon type implant• Incorporation of porous coating of tantalum• Rough surface rather than smooth• Proper fail-safe mechanism

Limitations, future work and ethics

Limitations-Not enough clinical data-High costs of the methodFuture Work- Use of antimicrobial membranes- Incorporation of soft tissues for load transfer

Ethics

• Debated use in sports• Can be afforded by a small section of society

Questions