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- Part Two: Etiology & Pathophysiology of Chronic Kidney
Disease By T. Parent Nurse Educator, PHC Community Hemodialysis
Units 2015
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- Glomerular disorders
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- Nephrotic & Nephritic syndromes Nephritic syndrome the loss
of a lot of blood Nephrotic syndrome the loss of a lot of protein
Proteinurea Hypoalbuminemia Edema Hyperlipidemia Hematuria
Hypertension Oliguria Azotemia
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- Associated Diseases Minimal change glomerulonep hritis Focal
Segmental glomeruloscl erosis Membranous Glomerulonep hritis Post
streptococcal glomerulonep hritis IgA Nephropath y Rapidly
progressive glomerulone phritis Goodpast ures Vasculitis disorder
Wegners granulomat osis Microscop ic polyangiti s Churg Strauss
disease Membranoprolif erative Glomerulonephri tis Henoch-
Schonlein purpura Diabetic Nephropathy
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- Vascular Diseases Microscopic Polyangiitis Wegeners BLOOD
VESSEL SIZESmall to Medium BLOOD VESSEL TYPEArterioles to venules,
And sometimes Arteries and veins GRANULOMATOUS INFLAMMATION NOYES
LUNG SYMPTOMSYES 1 GLOMERULONEPHRITISYES RENAL HYPERTENSIONNO
MONONEURITIS MULTIPLEX COMMONOCCASIONA L SKIN LESIONSYES 2 GI
SYMPTOMSNO EYE SYMPTOMSYES 4 ANCA-POSITIVITY75%65-90%
CONSTITUTIONALSYMPT OMS YES 5 NECROTIZING TISSUEYES
MICROANEURYSMSRARELY
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- Medullary sponge kidney
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- Neoplasms
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- Interstitial diseases Chronic tubulointerstitial nephritis
(CTIN): Acute interstitial nephritis (AIN) allergic drug reactions
infections immunologically mediated disorders infections reflux or
obstructive nephropathy drugs