Post on 21-Apr-2017
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If You Fail to Plan,
The only place where success comes before work is in a dictionary!
Vidal Sassoon
MX1002-PAS-Wk7-RS
PAS-Respiratory Pathophysiology
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PathophysiologyRespiratory SystemDr. Venkatesh M. Shashidhar.Associate Professor & Head of Pathology
MX1002-PAS-Wk7-RS
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Introduction to Resp. Sys:10,000L/day of air filtered, moistened, warmed, O2/Co2. exchanged.!Full capacity 6L. (500ml at rest)Sinusitis, pharyngitis, laryngitis* URIPneumonia: Inflammation of lung * LRIChronic: COPD, Fibrosis Smoking.Commonest internal Cancer.Respiratory tract inflammations - commonest in medical practice.Enormous morbidity & mortality.Important medical learning.Doctors daily bread.!
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Normal Lung
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Respiration Respiratory system:5
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Respiration Respiratory system:6
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Normal Lung
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Alveolar Gas Exchange:8
Co2O2
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Lung Function testing:9
Expiration
0 ------- Volume ---------------6L
Inspiration
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Lung Function Testing:Total Lung Capacity (TLC) 6L male/4.7L fem.Tidal Volume (TV) 500 / 390mlForced Vital Capacity (FVC) 4.8L / 3.7LForced Expiratory Volume in 1 Sec - FEV1FEV1/FVC (FEV1%) - 7580% normal. In Obstructive diseases (COPD) FEV1 low & FVC high. So FEV1/FVC is low (