Pediatric Optometry Pediatric Optometry Lecture 1 Lecture 1

Ocular embryologyOcular embryologyMutez Gharaibeh,MDMutez Gharaibeh,MD

► 22/10……….22/10……….► 29/10……….29/10……….► 5/11…………5/11…………► 12/11……….12/11……….► 19/11………. 19/11………. FirstFirst► 26/11……….26/11………. ► 3/12…………3/12…………► 10/12……….10/12……….► 17/12……….17/12……….► 24/12……….24/12……….► 31/12………. 31/12………. ► 7/1………….. 7/1………….. SecondSecond► 14/1…………14/1…………last date to deliver the reportlast date to deliver the report ► 22/1…………22/1………… FinalFinal

►First : 25 marks .First : 25 marks .►Second : 25 marks .Second : 25 marks .►Report: 10 marks .( How to prescribe Report: 10 marks .( How to prescribe

eyeglasses in children ).eyeglasses in children ).►Final : 40 ( 30+10 marks).Final : 40 ( 30+10 marks).►10 marks : evaluation.10 marks : evaluation.

http://www.med.unc.edu/embryo_imaghttp://www.med.unc.edu/embryo_images/unit-eye/eye_htms/eye016.htmes/unit-eye/eye_htms/eye016.htm

almutez@yahoo.comalmutez@yahoo.com

Weeks 3-4Weeks 3-4

CAUDAL

ROSTRAL

Anterior neural plate

Eye fields

Prosencephalon(forebrain)

►Optic sulcus Optic sulcus ►Optic grooveOptic groove►Optic vesicles.Optic vesicles.

►Neuroectoderm.Neuroectoderm.- Retina , Iris , - Retina , Iris , Optic nerve.Optic nerve.

►Surface ectoderm.Surface ectoderm.- Lens.- Lens.

► Mesoderm.Mesoderm.- vascular and fibrous- vascular and fibrous coats of the eye.coats of the eye.

Optic groove

Ectoderm

Lens placode

Optic vesicle

http://upload.wikimedia.org/wikipedia/commons/1/15/Persistent_hyperplastic_primary_vitreous.jpg

Lens vesicle

Optic stalk

Surface ectoderm

Optic cup

Choroidal fissure normally closes by the 6Choroidal fissure normally closes by the 6thth week. week.

Optic vesicle

Hyaloid artery.

Iris colobomasIris colobomas

Retinal colobomaRetinal coloboma

Persistent hyaloid arteryPersistent hyaloid artery

Bergmeister papillaMittendorf dot

PHPVPHPV►Persistent hyperplastic primary Persistent hyperplastic primary

vitreous .vitreous .

Leukocorea

CorneaCornea►Surface epithelium- etoderm.Surface epithelium- etoderm.

► Inner layers – Neural crest cells.Inner layers – Neural crest cells.

Optic nerve myelinationOptic nerve myelination► Incomplete @ birth.Incomplete @ birth.►Complete by 10 weeks of life.Complete by 10 weeks of life.►Stops off the optic never head.Stops off the optic never head.

EyelidsEyelids

►Fuse by the beginnig of second Fuse by the beginnig of second trimester ( 13-14weeks of trimester ( 13-14weeks of embryogenesis).embryogenesis).

►Remain adherent until about the 26 Remain adherent until about the 26 week of embryogenesis. week of embryogenesis.

Microphthalmia

►Microphthalmia.?Microphthalmia.?►Nanophthalmia.?Nanophthalmia.?►Anophthalmia.?Anophthalmia.?►Cryptophthalmia.Cryptophthalmia.؟؟►Cyclopia.?Cyclopia.?