Pick up the 2 packets from the front table. 1. Announcements 2. Cell Membrane Packet 3. Cell...

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Pick up the 2 packets from the front table.

1. Announcements2. Cell Membrane Packet3. Cell Transport Packet

Objective: define roles of organelles and relate to function of cell as a whole

HW: RR "Flower & Fly"Be working on your guided reading packetsNo organelles projectCells test is moved to Friday 10/21

Pick up a packet and find a group of 4. I'll know you're ready when you're seated in the back at a table with your group of 4.

1. Cell Membrane 3D Representation

Objective: relate cell membrane structure to function

HW: RR "Flower & Fly"Be working on your guided reading packetsNo organelles projectCells test is moved to Friday 10/21

What are the major AP Bio themes connected to cells?

1. Harvard Cell Videos2. Ch 6 notes

Objective: identify major AP Bio themes

HW: Cells Unit Test FridayAll packets due Friday

1. Magnification -

Resolving power -

2. Electron microscopes -

Advantages:

Disadvantages

SEM:

tobacco seedmouse kidney glomerulums

TEM:

myelinated axon

human neutrophil

4. Cell fractionation

5. Domains of prokaryotic cells

Prokaryotes Eukaryotes

Take out Ch. 6 reading guide and be ready to go.

1. Ch. 62. Lab: Diffusion & Osmosis Part A Demo

Objective: understand concepts of Ch. 6

HW: All 4 packets due FridayNoodle Packet due FridayTest Corrections due Friday

7.

8. Surface area to volume:

9. How have neurons and intestinal cells increased surface area?

Nuclear lamina -

· a dense (~30 to 100 nm thick) fibrillar network near the inner nuclear membrane and the peripheral chromatin · composed of intermediate filaments and membrane associated proteins

· providing mechanical support · the nuclear lamina regulates important cellular events such

as DNA replication and cell division · participates in chromatin organization

· anchors the nuclear pore complexes embedded in the nuclear envelope.

Nuclear matrix -

· network of fibres found throughout the inside of a cell nucleus

· somewhat analogous to the cell cytoskeleton

· like a dynamic sponge with open compartments for free diffusion of molecules in the nucleus

Chromosomes:

Chromatin:

Nucleoli:

Ribosomes: site of protein synthesis

Free: location & product:

Bound: location & product:

Endomembrane System:

Rough ER:

Smooth ER:

Golgi body:

Vesicles:

Smooth ER:

1. synthesize lipids and steroids

2. metabolism of carbs

3. drug detoxification*tolerance to alcohol and barbiturates

4. regulate calcium concentration

Rough ER:Makes proteins

Serves as membrane factory for the cell

Manufactures its own membrane proteins and phospholipids

Golgi Body:

Products from rough ER enter on cis side. Glycoproteins are modified by Golgi body enzymes. Leave out the trans side in a vesicle that fuses with cell membrane.

Makes pectin and other plant polysaccharides

Marks products with "ID tags" and they are sorted like zip codes

Lysosomes:

Digestive sacs with acidic pH

"Suicide sacs"

Intracellular digestion - fuse with food vacuole or worn out cell parts

Ex: white blood cells (macrophages) in humans

Functions of Cytoskeleton:

1. mechanical support and shape

2. cell motility

3. regulation of biochemical activities - if you pull on cytoskeleton, it can trigger changes within the cell

Microtubules functions:

1. Motility (cilia and flagella)

2. Separation of chromosomes (guide during division)

3. Cell Structure and Shape

4. Organelle movements and transport

Microfilaments functions:

1. maintain cell shape

2. change cell shape

3. muscle contraction

4. cytoplasmic streaming

5. cell motility (pseudopods)

6. cell division (cleavage furrow)

Actin and motor protein myosin work together in muscle contraction

Myosin walks along actin fibers

Intermediate filaments functions:

1. maintain cell shape

2. form nuclear lamina

3. anchor organelles (nucleus) in place

Cell Wall:

1. protects cell

2. maintains shape

3. prevents excessive uptake of water

Made of: fibrils of cellulose embedded in other polysaccharides and proteins

Primary cell wall: in young plants

Between cell walls - middle lamella (pectin - used to thicken jams and jellies), holds cells together

As a plant ages, develops a secondary cell wall inside primary cell wall

Perforated by plasmodesmata

PLANTS: Plasmodesmata: channel through cell walls which water and small solutes can pass freely from cell to cell

Extracellular Matrix:

Glycoproteins - collagen (half of protein in human body) - strong fibers outside cells

Proteoglycans - a type of glycoproteins into which collagen is embedded, core protein surrounded by carbs

Fibronectin - glycoprotein that attaches cell to ECM

Integrins - cell surface proteins to which fibronectin attaches

Fibronectin

No passage of materials:Tight Junctions: tightly pressed bound together by proteins to

prevent leakage of extracellular fluid across epithelial cells

Desmosomes: (anchoring junctions) rivets, fastening cells into strong sheets; intermediate filaments made of keratin anchor desmosomes in cytoplasm

Passage of materials:Gap Junctions: (communicating junctions) cytoplasmic

channels from one cell to another; specialized proteins that surround a pore through which ions, sugars, amino acids and other small molecules may pass; necessary for communication as in heart muscle and animal embryos

1. Diffusion and Osmosis Lab

Objective: define osmosis and diffusionpredict outcome of diffusion

HW: be working on all 4 packets all due Friday2 count as extra points on test2 count as a lab grade

Cell Membrane packets and noodles due FridayCells Unit Test Friday