Prospective Urban and Rural Epidemiology Study

PURE

Patricio López-Jaramillo, MD, PhD

Lina Patricia Pradilla MD

National Coordinator

Colombia

PURE - URBAN

Bucaramanga• 300 subjects• Sampling by blocks• All economical social

levels representated• 01 1XX XXX 01

PURE - RURAL

• 317 subjects• Included three areas:

– Aratoca (01 2XX)– Barichara (01 3XX)– Villanueva (01 4XX)

STATUS OF COLOMBIAApplied Surveys

URBAN RURAL

MEN 93 126

WOMEN 242 191

NON-RESPONDER

20 0

TOTAL 355 317

STATUS OF COLOMBIA

Examinated population

URBAN RURAL

MEN 87 126

WOMEN 213 191

TOTAL 300 317

MALEUrban (n=87) Rural (n=126)

pMean SD Mean SD

Age 51.8 9.3 50 10 NS

Systolic BP 131.0 17.4 133.4 18.4 NS

Diastolic BP 82.4 10.9 82.5 10.8 NS

Weight 75.8 11.2 67.6 10.9 <0.001

Height 167.8 6.3 167.8 6.48 NS

BMI 26.8 3.3 24 3.7 <0.001

Waist 90.2 9.3 85.6 9.97 0.0001

Hip 97.1 6.9 91.7 8.2 <0.001

W/H ratio 0.92 0.06 0.93 0.09 NS

Glycemia 98.6 21.6 85.6 16.5 <0.0001

FEMALEUrban (n=213) Rural (n=191)

pMean SD Mean SD

Age 51.0 9.8 49.9 9.5 NS

Systolic BP 128.1 23.0 134.2 22.2 0.0019

Diastolic BP 79.9 11.0 83.4 12.7 0.0032

Weight 65.7 13.0 60.5 10.6 0.0001

Height 154.1 6.3 154.2 6 NS

BMI 27.7 5.5 25.4 4.2 <0.0001

Waist 81.0 11.5 80.7 10.3 NS

Hip 99.5 9.8 95.2 9.2 <0.0001

W/H ratio 0.81 0.07 0.84 0.07 <0.0001

Glycemia 96.7 20.2 87.6 19.6 <0.0001

MALE

Urban (n=87) Rural (n=126)p

Mean SD Mean SD

Arm 30.9 2.8 27.5 3 <0.0001

Calf 36.6 3.3 35.2 3.2 0.0016

Head 56.1 1.6 55.2 2 0.0001

Grip Strenght

36.1 7.7 34.4 7.5 NS

FEMALE

Urban (n=87) Rural (n=126)p

Mean SD Mean SD

Arm 30.4 4.3 27.3 3.1 <0.0001

Calf 35.5 3.5 34.2 3.8 0.0009

Head 54 1.3 53.4 1.8 0.0001

Grip Strenght

22.3 4.9 24.3 5.1 0.0001

Prevalence Blood Pressure ≥135 / ≥85

Total Urban Rural p

Total sample (%)

276 (44.7)

124 (44.9)

152 (55.0)

0.0913

Men (%)

108 (50.9)

45 (41.6)

63 (58.3)

0.8495

Women (%)

168 (41.5)

79 (47.0)

89 (52.9)

0.0529

p value: Х2 test urban vs rural

Prevalence Obesity Body Mass Index > 30Kg/m2

Total Urban Rural p

Total sample (%)

101 (16.3)

71 (70.2)

30 (29.7)

<0.0001

Men (%)

24 (11.2)

16 (66.6)

8 (33.3)

0.0063

Women (%)

77 (19.0)

55 (71.4)

22 (28.5)

0.0003

p value: Х2 test urban vs rural

Prevalence Abdominal Obesity Waist Circumference

Total Urban Rural p

Men* (%)

78 (36.7)

45 (57.6)

33 (42.3)

<0.0001

Women** (%)

192 (47.5)

103 (53.6)

89 (46.3)

0.724

* Men: Waist circumference ≥ 90 cm

**Women: Waist circumference ≥ 80 cm

p value: Х2 test urban vs rural

Prevalence of Fasting plasma glucose >100 mg/dl

Total Urban Rural p

Total sample (%)

121 (19.6)

89 (73.5)

32 (26.4)

<0.0001

IFG (%)93

(15.0)69

(74.1)24

(25.8)<0.0001

Type 2 DM(%)

28 (4.0)

20 (71.4)

8 (28.5)

0.0135

p value: Х2 test urban vs rural

Impaired Fasting Glucose

Total Urban Rural p

Male (%) 27 (12.6) 15 (74.0) 7 (25.9) 0.0002

Female (%) 66 (16.3) 49 (74.2) 17 (25.7) 0.0001

Type 2 Diabetes Mellitus

Male (%) 7 (3.2) 5 (71.4) 2 (28.5) 0.0942

Female (%) 21 (5.2) 15 (71.4) 6 (28.5) 0.0778

p value: Х2 test urban vs rural

LESSONS LEARNED

• Urban: 1 month to complete all study in 300 subjects

• Rural: 1.5 month

• Personal: six ( 2 MDs, 3 nurses, 1 laboratory technician, all full time)