Protect, Enhance, and Save Lives - 1 - III ARDENT Annual Workshop 29/09-02/10/2014 IBA Dosimetry...

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Protect, Enhance, and Save Lives - 1 -

III ARDENT Annual Workshop

29/09-02/10/2014IBA Dosimetry

Francesca BiselloESR 10

Protect, Enhance, and Save Lives - 2 -

OutlineResearch Activities

ConferencesTraining and Secondments

I. Research Activities

II. Conferences

III. Trainings and Secondments

Outline

Protect, Enhance, and Save Lives - 3 -

Research Activities

Protect, Enhance, and Save Lives - 4 -

Dosepix Characterization

General overview

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix detector as Quality Assurance tool in diagnostics

0 10 20 30 40 50 600

2

4

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12

Energy(keV)

Counts

Protect, Enhance, and Save Lives - 5 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix Characterization

kVp-meter in mammography

Protect, Enhance, and Save Lives - 6 -

OutlineResearch Activities

ConferencesTraining and Secondments

October 2013 – October 2014:

Dosepix as kVp-meter in mammographyRadiation Tolerance studiesTemperature characterization

Dosepix Characterization

Sum up of activities

Protect, Enhance, and Save Lives - 7 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationkVp-meter in mammography

o Image quality and dose depend on the xRay tube voltage

10 15 20 25 30 35 40 450

0.2

0.4

0.6

0.8

1

1.2

1.4

Energy (keV)

Coun

ts

Tube setting: 30 kV, 20 mAs

Mo-Mo

Big Pixels

Tube setting: 30 kV, 20 mAs

Mo-Mo

Protect, Enhance, and Save Lives - 8 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationkVp-meter in mammography

o kVp: fitting the end point of the spectrum

20 22 24 26 28 30 32 34 3622

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f(x) = 0.905925196214262 x + 3.35983643787807R² = 0.993008054945356

kVp MagicMax (kV)

En

d P

oin

t F

it D

ose

pix

en

erg

y d

epo

siti

on

sp

ectr

a (k

eV)

20 22 24 26 28 30 32 34 360

0.2

0.4

0.6

0.8

1

1.2

1.4

1.6

1.8

kVp (MagicMAx) (KV)D

iffe

ren

ce (

kV)

bet

wee

n k

Vp

(Mag

icM

ax)

En

dP

oin

t fi

t (D

ose

pix

)

Additional filtration: 0.3mm CuCounts/big pixel/s: 1.5 · 104 Hz [ count rate without filtration : 5· 104 Hz ]

Protect, Enhance, and Save Lives - 9 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix Characterization

RadiationTolerance studies

10-28/02/2014Secondment at CERNRadiation Tolerance Studies

Measurement Session:Accumulated dose for the test: 5 kGy in step of 200 Gy Tube settings: 40 kV, 2 mA dose rate 4.83 Gy/min

Protect, Enhance, and Save Lives - 10 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationRadiation Tolerance studies

Protect, Enhance, and Save Lives - 11 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationRadiation Tolerance studies

Poster Presention IEEE 2014, 8-15 November 2014 “Investigation on the radiation tolerance of Dosepix detector” F. Bisello, W.S. Wong , E.Frojdh , J.Alozy I. Ritter, A.Zang, M. Campbell, J.C.Celi, G.Anton and T.Michel

o Deeper analysis of effect around mammographic energieso Investigations in damages in the sensor or in the chip

Protect, Enhance, and Save Lives - 12 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix Characterization

Temperature Characterization

First Measurement Session: CERN (secondment)Addidtiona Investigations: IBA Dosimetry

Measurement Session:Range required by the regulation: 15°- 35 °CInstability < 1%

Protect, Enhance, and Save Lives - 13 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationTemperature Characterization

Protect, Enhance, and Save Lives - 14 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationTemperature Characterization

Source of instability (I):PLL circuit

Source of instability (II):Bias current of initial gain stage of

the discriminator

Protect, Enhance, and Save Lives - 15 -

OutlineResearch Activities

ConferencesTraining and Secondments

Dosepix CharacterizationTemperature Characterization

Next steps:

o Evaluate the possibility to bypass the PLL circuit

o Find other more stable configurations for the analog front end

Protect, Enhance, and Save Lives - 16 -

OutlineResearch Activities

ConferencesTraining and Secondments

Other Activities

SFD diodes

Machine and Plan QASmall Field external Radiotherapy

Protect, Enhance, and Save Lives - 17 -

OutlineResearch Activities

ConferencesTraining and Secondments

Other ActivitiesSFD diodes

Studies on sensitivity dependence from:

• Dose• Dose per pulse• Dose rate

Protect, Enhance, and Save Lives - 18 -

OutlineResearch Activities

ConferencesTraining and Secondments

Other ActivitiesSFD diodes

Oral Presentation, RESMDD14, 8-10 October 2014 “Development of silicon monolithic arrays for dosimetry in external beam radiotherapy”

F. Bisello, M. Bucciolini, M. Bruzzi, D. Menichelli, M. Scaringella, C. Talamonti, M. Zani1,2

Protect, Enhance, and Save Lives - 19 -

Conference

Trainings

Secondments

Protect, Enhance, and Save Lives - 20 -

OutlineResearch Activities

ConferencesTraining and Secondments

Conferences 2014

DPG Mainz, 25th March 2014Oral Presentation “Characterization of the Dosepix detector under clinical conditions ”

RESMDD Florence, 8-10 October 2014Oral Presentation “Development of silicon monolithic arrays for dosimetry in external beam radiotherapy”

IEEE 2014 Seattle, 8-15 November 2014Poster Presentation “Investigation on the radiation tolerance of Dosepix detector”

Protect, Enhance, and Save Lives - 21 -

OutlineResearch Activities

ConferencesTraining and Secondments

Planned Training and Secondments

Business and Administration training, ST Microelectronics

Secondment at the UPENN University Hospital, Phyladelphia (tentative: 16-28 November 2014):

Measurements on plan QA with silicon monolithic array

Trainings on clinical quality assurance routine (to be defined)

Protect, Enhance, and Save Lives - 22 -

Thank you very much for your attention