Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3...

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Protein-DNA Interactions

The central dogma of biology

Genomic DNA

DNA packaging

DNA replication

DNA replication

The genetic code

Transcription of DNA

Translation of mRNA - Protein synthesis

DNA structure

DNA structure

DNA structure

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Protein-DNA interactionsSequence specific vs. non-specific recognition

The RNA polymerase

The RNA polymerase

The RNA polymeraseRNA synthesis begins at promoter sites

The RNA polymeraseRNA synthesis begins at promoter sites

Gene regulationNegative regulation

Gene regulationNegative regulation

Lactose repressor

Gene regulationNegative regulation

Lactose repressor

Gene regulationPositive regulation

Gene regulationPositive regulation

cAMP Receptor Protein (CRP)

Gene regulationPositive regulation

Gene regulationPositive regulation

Gene regulationPositive regulation