Post on 14-Oct-2020
transcript
Dr. Wonnop Visessanguan Executive Director
National Center of Genetic Engineering and Biotechnology (BIOTEC)
Thailand: Overview of the Biotechnology Sector and Strategy
to Develop Thailand's Bio-Economy
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8 June 2020. Dr. Suvit Maesincee, Minister of Higher Education, Science, Research and Innovation (MHESI) brought a team of eight top executives representing industries, entrepreneurs, academia, government agencies and people sector to meet Prime Minister General Prayut Chan-o-cha to discuss the use of Bio-Circular-Green Economic (BCG) Model to drive the national agendas which include food security, public health security, energy security, job security, environmental sustainability, as well as social inclusiveness. 2
Source: Ministry of Higher Education, Science, Research and Innovation
Food security
Health security
Energy security
Employment security
Environmental and natural resource security
Paradigm Shift: Modernization & Wealth Sustainability & Security
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BCG Economy: A key global driver of economic development post COVID-19
Source: Ministry of Higher Education, Science, Research and Innovation
3 Guiding Principles
Strengthen from Within, Global Thai Linkage
Going Forward Together, Left No One Behind
Sufficiency Economy Philosophy (SEP) for Sustainable Development Goals (SDGs)
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Food &
Agriculture Medical &
Wellness Energy &
Biochemical materials Tourism &
Creative Economy
INNOVATION
PRODUCTIVITY
Omics Bio-Materials
Bio-Energy Materials
Biomass Agro-based
Story-Telling
Biodiversity & Biotechnology
as drivers for
BCG economy
BCG Digital Platform
3.4 Trillion Baht
(21% GDP) 16.5 Million Employment
4.4 Trillion Baht
(24% GDP) 20 Million Employment
BCG MODEL: Aim for Distributive Economic Prosperity
Food &
Agriculture Medical &
Wellness Energy &
Biochemical
materials
Tourism &
Creative Economy
Biodiversity Cultural Diversity
5 Years
Precision
Medicine
Bioprocess
Biorefinery
High Value
Food Ingredients
Biosimilar, Herbal &
Medical Products
Bioactive Compound Digital Tourism
Management System
Geographical
Identification
High Value
Tourism High Value
Substance
High Value
Functional Food
Seeds/ Precision Farming
Healthy People
(Prediction/Prevention/Precision) Hygienic Kitchen of the World High Value-Added Products Happy destination
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Source: Ministry of Higher Education, Science, Research and Innovation
Functional ingredients Functional foods 6
Source: Ministry of Higher Education, Science, Research and Innovation
Gene Therapy
Vaccine and Biosimilar
Medical Equipment
Clinical Research
Tele-Medicine
Herb Extraction For Medicine and Cosmetic Products
Genomic Data for Personalized Treatment
Thailand Medical Hub
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Source: Ministry of Higher Education, Science, Research and Innovation
BCG MODEL in Energy, Material and Biochemical Sector
Agricultural Product and Waste
Investment Promotion
Industrial Development
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Biotechnology and value creation in
biochemical industry
Within a year 3 years 5 years Source : Mitr Phol Group
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Source: Ministry of Higher Education, Science, Research and Innovation
Tourism in Secondary
Cities and Communities
High Quality Tourism
Wellness Tourism
Standard For Tourism Sites
(Convenience / Clean / Safe)
Sustainable Tourism Standard System
National Guideline
for Tourism
Creative Cities and Creative Products
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Source: Ministry of Higher Education, Science, Research and Innovation
Publicly-led investment
Cash-aid policy
Annual funding
Individual project- based funding
Economic growth based on traditional industry
External-dependent growth
Individual contribution
Enterprise-led investment with government support
Government investment
Multi-year funding
Integrated project funding
New S-curve industry
Strengthening local economy and global linkage
Collective action through contribution of 4 sectors
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Paradigm shift
Paradigm shift
Now Then
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Content - Thailand biotechnology development policy - Agriculture and Food - Plant breeding development – Animal farming- Genetic engineering policy: Transgenic plants - disease diagnosis and services - Medicine and Health Medical devices - Diagnostic kits - Biopharmaceuticals – Stem cell technology - Vaccine - Biorefinery Industry - Bio Energy - Biomass - Biogas - Ethanol-Biodiesel - Bio Industry - Bioplastics - Why Thailand - Skilled labor - Access to markets - Attractive investment incentives - Development network of support organizations - National Science and Technology Development Agency (NSTDA) - National Center for Genetic Engineering and Biotechnology (BIOTEC) - Thailand Science Park (TSP) - National Biopharmaceutical Facility (NBF) - Research and development Certification Committee Secretariat(RDC) - Thailand Center of Excellence for Life Sciences (TCELS) - Thailand Instiute of Scientific and Technological Research (TISTR) - Biodiversity - Based Economy Development Office (BEDO) - The Venture Capital (VC) Industry in Thailand Link: http://aseanup.com/overview-biotechnology-thailand/
Overview of biotechnology in Thailand
Source: Ministry of Higher Education, Science, Research and Innovation
Collection, preservation and utilization
of bioresources
A collaborative human genome
research network to enable
precision medicine
Foster local economy
development
Improve agricultural
practice through precision
agriculture (TP Map/ Agrimap/ Hydro&Geo Map)
Scaling up technology:
Lab-scale to industrial–scale (Waste to Wealth
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collection
85,864 Microbial strains (bacteria/ fungi/ yeasts/ protists/ algae/ virus)
Thailand Bioresource Research Center
(TBRC)
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https://www.tbrcnetwork.org/
PLATFORMS
BCG MODEL
HEALTH &
MEDICAL
FOOD AND
AGRICULTURE
ENERGY AND
MATERIAL
TOURISM
THAI
BIORESOURCES
CATALOGUE
ECOSYSTEMS
PRECISION
MEDICINE IN
THAILAND
NBT FOR LONG-TERM CONSERVATION AND UTILIZATION
OF THAI BIORESOURCES
430 SAMPLES
• CROP VARIETIES
• HERBS
• WILD CROP SPECIES
• INDIGINOUS SPECIES
2,400 SAMPLES
200 PLANT SAMPLES
9,000 MICROBE SAMPLES
2,300 SAMPLES
BASIC SCREENING
FOR INDUSTRIAL
APPLICATIONS • ENZYME
• FATTY ACIDS
2,300 SAMPLES
HUMAN GENOME
Precision medicine • HUMAN GENOME
GENOMIC
DNA
BANK
HERBARIUM
DIGITAL
BANK
FUNGARIU
M
MICROBE
BANK
BIOBANKING STANDARDS
CORE
TECHNOLOGY
• CRYOPRESERVATION (SEED/ TISSUE)
• ADVANCED TAXONOMY (MALDI-TOF MS)
• ECOLOGICAL MODELLING
• BIOINFORMATICS AND DATA SCIENCE
DATA
TECHNOLOGY
• GENOTYPE/ PHENOTYPE ANALYSIS
• POPULATION ANALYSIS
• METAGENOMICS OF MICROBIOME
• AUTOMATED SAMPLE
STORAGE -20C/ -80C
• BIOTYPER/
MALDI-TOF MS
• HPC; HIGH
PERFORMANCE
COMPUTING
INFRA-
STRUCTURE • SEED GERMINATION
SCANALYZER
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TISSUE
BANK
SEED
BANK
160 SAMPLES • HERBS
150 SAMPLES
ONLINE DATABASE
ANALYTIC PLATFORM
• PLANT
• MICROBE
• ECOLOGY
National Biobank of Thailand
Genomics Thailand
5 Targeted Diseases • Rare diseases
• Cancer
• Non-communicable diseases
• Pharmacogenomics
1,175 Whole genome sequencing (WGS)
1,092 Whole exome sequencing (WES)
2,505 SNAP Array data
GOV / Private
Enterprise
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https://genomicsthailand.com/Genomic/about
National Omics Center
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Software
Park
Southern Science Park
Northern
Science Park
Northeastern
Science Park
High–speed Train &
Dual-track Railway
Lam-Chabang &
Map-Ta-Phut
Seaports
Industrial Estate
Development
U- Tapao
International Airport
EECi
Thailand’s Regional Science Parks & Eastern Economic Corridor of Innovation (EECi)
A Translational
Research Hub Bridging
Research & Investment
across Thailand
Thailand
Science Park
Universities/ Research Institutes
Regional Science Parks
Target Industries
Modern Agriculture & Adv. Biotechnology
Bio-Fuels & Bio-Chemicals
Automation, Robotics & Smart Electronics
Aviation & Aerospace
High Performance Battery & Modern
Transports
Medical Device Startups / SMEs LEs / MNCs
TRL: 1 2 3
Laboratory
Development
4 5 6
Scale-up, Demonstration,
Localization
7 8 9
USD 43 bil. Investment in EEC
(cumulative 5 year Projection)
EEC i
Smart City
Development
Source : EECi, NSTDA 18
https://www.eeci.or.th/th/
EECi Biorefinery Pilot Plant
Overall construction progress 34.39%
Non-GMP pilot plant 47.26% GMP pilot plant 57.43%
Joint venture: Bio Base Europe Pilot Plant
+ NSTDA
The National Science and Technology Development Board approved
the establishment of “Bio Base Asia Pilot Plant” to manage the biorefinery pilot plant
on May 25,2563.
Biorefinery Pilot Plant
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Innovative immunotherapeutic and next generation novel long-acting biologics
Business expertise in South East Asia and execution capacity
Thailand’s #1 cGMP capacity and CMC expertise
To be ASEAN’s No.1 R&D-based biotechnology company with manufacturing capabilities
Kingen Holdings Stakeholders
20 http://www.nbf.kmutt.ac.th/
• Thailand has already been prepared for new economy.
• BCG model is now fully activated and put in action by Thai government and key stakeholders to shape up a country after disruption by COVID-19.
• International partners and global network are considered as key enablers.
• With more experiences on new mechanisms and business models, we will move forward at higher speed.
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Conclusions
Biodiversity Human Capital Infrastructure
Thailand Southeast Asia's prime destination for biotechnology development
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Thank You
National Center for Genetic Engineering and Biotechnology (BIOTEC) 113 Paholyothin Rd., Khlong Nueng, Khlong Luang, Pathum Thani 12120 Thailand Tel:66 2564 6700 Fax:66 2564 6701 to 04
www.biotec.or.th
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