THE ENDOCRINE SYSTEMCh 45

I. Overview of intercellular communication

Similarities?

Differences?

• The ways that signals are transmitted between animal cells are classified by two criteria –The type of secreting cell–The route taken by the signal in reaching its

target

• Endocrine signaling:–Hormones secreted into blood and travel to

target cells– Involved in reproduction, growth and

development, homeostasis

II. Endocrine Glands and Their Hormones

Two main groups of hormones:Lipid soluble (steroids)Water soluble (proteins, peptides, amines) Where is receptor for lipid soluble hormone?

Where is receptor for water soluble hormone?

• What determines whether a target cell will respond to a hormone?

http://www.nlm.nih.gov/medlineplus/ency/anatomyvideos/000048.htm

III. Insulin and Glucagon: Maintaining Blood Glucose Balance

Type of feedback loop?

• Insulin raises blood glucose levels• Glucagon lowers blood glucose levels• They are antagonistic hormones• http://www.youtube.com/watch?v=CLv3SkF_Eag&list=PLFCE4D99C4124A27A

IV. Calcitonin and Parathyroid hormone regulate blood calcium levels

Calcitonin lowers blood calcium levelsPTH raises blood calcium levels  http://www.mhhe.com/cgi-bin/netquiz_get.pl?qfooter=/usr/web/home/mhhe/biosci/genbio/animation_quizzes/animate_79fq.htm&afooter=/usr/web/home/mhhe/biosci/genbio/animation_quizzes/animate_79fa.htm&test=/usr/web/home/mhhe/biosci/genbio/animation_quizzes/animate_79q.txt&answers=/usr/web/home/mhhe/biosci/genbio/animation_quizzes/animate_79a.txt