TOTAL HIP ARTHROPLASTY IN ADULT PATIENTS WITH SICKLE CELL DISEASE (1983-2005) P. Hernigou Hospital...

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TOTAL HIP ARTHROPLASTY IN ADULT PATIENTS WITH SICKLE CELL DISEASE

(1983-2005)

P. Hernigou Hospital Henri Mondor 94000 Créteil

336 hips(M=15/year since 22 years)

SICKLE CELL DISEASE

SICKLE CELL DISEASE

Total hip replacement in such patients who are less than forty years old has been associated with high rates of complications and revisions. Also, the majority of such patients with sickle cell disease have been reported to have a high prevalence of failure of components fixation

The purpose of the present study was to analyze the results after primary total hip arthroplasty with cement in a group of patients who had sickle cell disease

• anatomic abnormalities

• infection of the hip during childhood

• Transfusions and anemia

• Allo immunisation

• Pulmonary Infarctus

• Revisions

Problems

The anatomic abnormalities

» The anatomic abnormalities may include »abnormal location of neurovascular structures

secondary to soft-tissue contractures, »an abnormal location of the hip center,»a limb-length discrepancy,» a small acetabulum and femoral canal» increased anteversion of the proximal part of the

femur.

Medullary osteonecrosis

Risk Factors of Intraoperative perforation of the femur

Levels of Deformity Femoral Neck Deformity

Greater Trochanteric Deformity

Levels of Deformity Metaphyseal Deformity

as a result of an osteotomy.

Diaphyseal Deformity

OSTEOTOMIES

20 ans

dysplastic acetabulum

dysplastic acetabulum

dysplastic acetabulum

Coxa profonda

• anatomic abnormalities

• infection of the hip during childhood

• Transfusions and anemia

• Allo immunisation

• Pulmonary Infarctus

• Revisions

Problems

10 hips in patients who had had infection of the hip during childhood

All the hips had cemented total hip replacements. The age of the patients at the time that the infection was contracted was an average of 12 years).

The average age of the patients at the time of the total hip arthroplasty was 32.4 years. The interval between active infection and arthroplasty was 24 years. All the hips had a quiescent period of infection of more than ten years. The average duration of follow-up was 8 years (range, five to fifteen years).

Two hips had recurrence of infection.

infections

inégalité

Fémur anormal

• anatomic abnormalities

• infection of the hip during childhood

• Transfusions and anemia

• Allo immunisation

• Pulmonary Infarctus

• Revisions

Problems

Transfusions:risk of allo-immunisation

pulmonary Infarctus

• anatomic abnormalities

• infection of the hip during childhood

• Transfusions and anemia

• Allo immunisation

• Pulmonary Infarctus

• Revisions

Problems

Results:336 hips

average follow-up: 10 years(10 to 20)

60 THA >10 years

Surgery at 18 years oldfollowup: 22 years

Followup: 22 years

Followup: 22 years

336 protheses

22 revisions

Infections 3

1 revision 7

2 revisions 2

3 revisions 1

4 revisions 3

Revisions: 6 %

Risk of iterative revisions

Conclusion• The management of hip arthroplasty with

sickle cell disease requires recognition of anatomical deformities

• Assessment begins in the preoperative period with recognition of significant risk factors, including previous surgery systemic medical conditions, as well as selection of suitable components.