WUSM Blood ConservationPhlebotomy Reduction Techniques Project

CRIT Collaborative Meeting6/25/2012Jennifer York, MDWashington University in St. Louis

Hypothesis and Specific Aims• Aim 1: The primary aim is to pilot the effectiveness of pairing evidence-

based Phlebotomy Reduction Techniques (PRT) with evidence-based Implementation Strategies (IS). We hypothesize that the use of evidence-based IS to apply the PRT will synergistically facilitate effective implementation.

• Aim 2: The secondary aim is to capture data on clinical outcomes of volume overdrawn, hemoglobin drop, and transfusion rate. We hypothesize that blood wastage, iatrogenic anemia and red blood cell (RBC) transfusions will be reduced with effective implementation of PRT.

• Aim 3: The tertiary aim is to capture data on implementation outcomes of acceptability (perceived usefulness) and adoption (use of the system). We hypothesize that use of evidence-based IS will improve these implementation outcomes.

Study Design

Pre-Implementation Data

• Detailed characterization of blood draws on 112 PICU patients

• Overdraw = the volume of blood removed in excess of requirements for any given lab set

• 87% of samples were overdrawn• Mean overdraw 0.8 ± 1 ml• 3.3 ± 2.5 ml blood/kg ( 0.5 ± 0.2 ml

blood/kg/day) was removed

Pre-Implementation Data

p<0.01 p<0.01

Pre-Implementation Data

p<0.01p<0.01 for group 1 vs. group 2p<0.01 for group 2 vs. group 3p<0.01 for group 1 vs. group 3

1

2

3p<0.01 for all categories* p<0.01 for CVC vs. others

*

Study Design

Preparation Phase

• PICU Nursing Staff REDCap Survey• PICU Nursing Staff Focus Groups

• Goals:– To identify driving forces for current practice– To identify barriers to change– To raise awareness– Ground level engagement

Study Design

PRT Implementation

• Phlebotomy Reduction Techniques– Bedside Minimal Volume Reference Guide

Bedside Minimal Volume Reference Guide

PRT Implementation

• Phlebotomy Reduction Techniques– Bedside Minimal Volume Reference Guide– Exclusive microtube use with environmental

engineering– Venous safe-draw system

Microtubes & Venous Safe-Draw

PRT Implementation

• Phlebotomy Reduction Techniques– Bedside Minimal Volume Reference Guide– Exclusive microtube use with environmental

engineering– Venous safe-draw system– Blood Culture volume policy change

PRT Implementation

• Phlebotomy Reduction Techniques– Bedside Minimal Volume Reference Guide– Venous safe-draw system– Exclusive microtube use with environmental

engineering– Blood Culture volume policy change

• Implementation Strategies– Educational Interventions– Nurse Champions– Audit and Feedback

Study Design

Post-Implementation Data

• Repeat detailed characterization of blood draws on 112 PICU patients

• Clinical Outcomes– Volume Overdrawn– Hemoglobin drop– Transfusion rate

Study Design

Implementation Assessment

• PICU Nursing Staff REDCap Survey• PICU Nursing Staff Focus Groups

• Implementation Outcomes– Acceptability (Perceived usefulness)– Adoption (Use of system)

AcknowledgementsContributors:

Washington University• Allan Doctor, MD• Philip Spinella, MD• Enola Proctor, PhD• Julie Hoerr, BSN, MSN• Richard Griffey, MD• Jennifer Jaffe, MPH, CCRP• Jessica Richards, RN, BSN, CCRN

Harvard University• Stacey Valentine, MD

Helen DeVos Children’s Hospital• Nabil Hassan, MD

Support at WUSM:

WUSM Pediatric Critical Care Translational Research Program• Lead by Philip Spinella• 7 Research Personnel

ICTS Dissemination and Implementation Methods Core• Supported by WUSM CTSA Award• Grant Number NIH UL1 RR024992

Washington University Network for Dissemination and Implementation Research

ICTS Research Design and Biostatistics Group