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Аннотации статей на английском языке PROFILACTICAL AND CLINICAL MEDICINE SCIENTIFIC JOURNAL 2008 № 4 PUBLIC HEALTH AND PUBLIC HEALTH SERVICES 01_983 © V.I. Orel, T.Sh. Kutushev, 2008 UDC: 614.2:65.012.45 Orel V.I., Kutushev T.Sh. Modern approaches to the use of information technologies in public health services // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - 4(29). – Р. 7-11. State Educational Establishment of Higher Professional Training «Sankt-Petersburg state pediatric academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 194100, St.-Petersburg, Litovskaya str., 2, tel. (812)542-39-83, tel./fax: (812)295-40-85, e-mail: [email protected] S u m m a r y . Last years government actively adopts the programs to increase usage of information technologies in health care, however, understanding of application in practice of these programs rarely is successful. It is related to low computer literacy of personnel and absence of possibility to promote qualification in this area. K e y w o a r d s : information technologies in health care, computer literacy of personnel. 1
Transcript
Page 1: ПУЗИН С - profclinmed.szgmu.ru  · Web viewprofilactical and clinical medicine. scientific journal. 2008 № 4. public health and public health services. 01_983 © v.i. orel,

Аннотации статей на английском языке

PROFILACTICAL AND CLINICAL MEDICINE

SCIENTIFIC JOURNAL

2008 № 4

PUBLIC HEALTH AND PUBLIC HEALTH SERVICES

01_983 © V.I. Orel, T.Sh. Kutushev, 2008

UDC: 614.2:65.012.45Orel V.I., Kutushev T.Sh. Modern approaches to the use of information technologies in

public health services // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 7-11.

State Educational Establishment of Higher Professional Training «Sankt-Petersburg state pediatric academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 194100, St.-Petersburg, Litovskaya str., 2, tel. (812)542-39-83, tel./fax: (812)295-40-85, e-mail: [email protected]

S u m m a r y . Last years government actively adopts the programs to increase usage of information technologies in health care, however, understanding of application in practice of these programs rarely is successful. It is related to low computer literacy of personnel and absence of possibility to promote qualification in this area.

K e y w o a r d s : information technologies in health care, computer literacy of personnel.

02_1009 © V.K. Yuriev, A.D. Rubin, E.V. Zelenova, M.H. Saifulin, E.P. Nikolaeva, V.S. Baskakov, 2008

UDC: 614.2-053.2/.6:616-082 Yuriev V.K., Rubin A.D., Zelenova E.V., Saifulin M.H., Nikolaeva E.P., Baskakov V.S.

Some problems of organization of specialized medical aid to children population // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 11-15.

State educational institution for high professional education “Saint-Petersburg State Pediatric Medical Academy by Federal agency for health services and social development”; 194100, Saint-Petersburg, Litovskaya str. 2; phone (812)2950646; fax (812)2954085; e-mail: [email protected], http://www.gpma.ru.

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S u m m a r y : The analysis of providing of medical help for Vologda children in five main specialties during 2003-2005 was carried out. A number of organizational troubles were revealed including low staffing of specialized pediatric service, insufficient succession in the work between physicians of narrow specialties and district pediatricians, weak material and technical supply, unreasonable organization and overloading of out-patient perception by doctors, lack of time for patients reception.

K e y w o r d s : out-patient clinic for children; specialized medical help; organizational troubles; Vologda.

I n f o r m a t i o n a b o u t t h e a u t h o r s :Yuriev Vadim Kuzmich, Doctor of Medicine, Professor, Honoured Scientist of FR, head

of the department of Public Health and Public Health Services of SEEHPT “Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav”; tel. (812)2951742; e-mail: [email protected].

Rubin Arkady Dmitrievich, Candidate of Medical Sciences, Vice-Chairman of the Committee for Public Health of Murmansk Region Government.

Zelenova Elena Vladimirovna, post-graduate student of the department of Public Health and Public Health Services of SEEHPT “Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav”.

Saifulin Marat Khasanovich, Candidate of Medical Sciences, chief physician of Children Tuberculous Hospital, Astrakhan.

Nikolaeva Ekaterina Pavlovna, Deputy-Chief Physician for Curative Work of Children Municipal Hospital N101, Moscow.

Baskakov Vladimir Sergeevich, Chief Physician of Children Municipal Hospital N1, Astrakhan.

03_1036 © N.A. Paskar, 2008

UDC: 616.13:616-084Paskar N.A. Detection of risk factors of cardiovascular diseases and arterial hypertension

due to monitoring data in unorganized population of Saint-Petersburg // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 15-18.

Almazov Federal Heart, Blood and Endocrinology Centre, 197341, St-Petersburg, Akkuratova str., 2, tel.: (812) -702-37-00, fax: (812)-702-37-01, E-mail:[email protected]

S u m m a r y . This research contains analysis of epidemiologic situation on hypertension and risk factors; the results of second stage of AH Monitoring in St-Petersburg, carried out as a part of federal program “Precaution and treatment of arterial hypertension in Russian Federation”, are presented.

K e y w o r d s : hypertension, cardiovascular disease risk factors.I n f o r m a t i o n a b o u t t h e a u t h o r : Paskar Nadezda Andreevna – candidate of medical sciences, Head of the

Department of Organization Medical Aid of Almazov Federal Heart, Blood and Endocrinology Centre, work tel.: (812)702-55-82, home tel.: (812) 543-01-89, mobile phone.: 8-921-980-46-27, e-mail:[email protected]

04_882 © R.A. Ryabtsev, 2008

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UDC: 614.2:616.9Ryabtsev R.A. Substantiation of organizational forms of early revealing and emergency

hospitalisation of city dwellers with infectious pathology // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 18-21.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; www.mechnik.spb.ru

S u m m a r y : The complex clinical-statistical analysis of medical aid to city dwellers with presence of an infectious pathology has revealed the clinical-statistical analysis of medical aid, that creation new and improvement of already existing organizational forms of early revealing and emergency hospitalization of the these patients is required. In conditions of constantly growing prevalence of infectious diseases and changes medico - social conditions reforming all structures infectious - epidemiological service of city is required.

K e y w o r d s : organizational forms, early revealing, emergency hospitalization, infectious diseases

I n f o r m a t i o n a b o u t t h e a u t h o r :Ryabtsev Roman Alexandrovitch - graduate student of the day department of public

health and public health services Saint – Petersburg state Medical Academy of Mechnikov. Home address: Saint – Petersburg, Ilyushina st., 13 – 2 – 39, Phone number: 8-911-986-99-56, Email: [email protected]

05_947 © S.Yu. Kladov, 2008

UDC: 614.252.1:340.6Kladov S.Yu. Forensic medical examination in evaluation of doctors activity and quality

of medical aid // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 21-24.

Regional official body of public health services «Bureau of a forensic medical examination of the Tomsk region», Russia, 634041, Tomsk, Vershinin's street, 26, 8(382-2) 55-82-43, e-mails: [email protected].

S u m m a r y . The major part in a legal estimation of adverse consequences of treatment, definition guilty and an estimation of size of the put damage is the service is judicial-medical examination. Last 5 years the increase in number of "medical" examinations that is connected with growth of references of patients and their relatives in law-enforcement and judicial bodies with applications for inadequate rendering medical aid is observed.

Most problem medical specialities there is a surgery, traumatology and obstetrics-gynecology that is connected with the raised risk of a failure during treatment. Quite often occasion for submission of statements of claim on affairs in which defects of rendering of medical aid were absent, or were insignificant, infringements of ethics and deontology from medical workers have served.

K e y w o r d s : forensic medicine examination, evaluation of doctors activity, quality of medical aid.

I n f o r m a t i o n a b o u t t h e a u t h o r : Kladov Sergey Jurevich – chief of Regional official body of public health services

«Bureau of a forensic medical examination of the Tomsk region», the candidate of medical

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sciences, 634061, Tomsk, street Kievskaja, 61- 11, 8(382-2)55-82-43, 8-913-827-67-87, e-mails: [email protected]

06_881 © G.Yu. Fedenko, B.P. Filenko, 2008

UDC: 614.2:616.366-089.87Fedenko G.Yu, Filenko B.P. Quality of life of patients after cholecystectomies performed

by different methods // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 24-28.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; www.mechnik.spb.ru

S u m m a r y : The article prersents index of postoperative quality of life after conventional cholecystectomy, laparoscopic and mini-approuch cholecystectomy in 3-6 years after surgery. No influence of the type of cholecystectomy on frequency of inadequate results was shown. The most typical reasons for inadequate results were progressive current of concomitant diseases.

K e y w o r d s : quality of life in patients, laparoscopic and mini-approuch cholecystectomy

07_942 © I.V. Polyakov, O.N. Kostin, 2008

UDC: 616-074:614.2Polyakov I.V., Kostin O.N. State, problems and ways of improvement of quality of

laboratory examinations // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 28-32.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y . In the article are presented result of the quality functioning laboratory regions Saratov, analyzed problems to organizations and quality undertaking the laboratory studies, are presented of the offer on quality management clinical laboratory studies.

K e y w o r d s : quality functioning laboratory regions Saratov, organizations, quality undertaking, quality management.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Polyakov Igor Vasilievich – Doctor of Medicine, Professor, Academician of MANEB,

honoured scientist of the Russian Federation, head of the course of Management and Economics of Public Health Services SEEHPT SPSMA named after I.I.Mechnikov, 195067 Saint-Petersburg, Piskarevsky prospect, 47, tel./fax:. 8-812-543-02-64, 8-812 740-15-24, е-mail: [email protected]

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Kostin Oleg Nikolaevich – Candidate of Medical Sciences, chief physician of the Saratov Clinical Municipal Hospital N9, doctoral candidate of the course of Management and Economics of Public Health Services at the department of Social-Humanitarien sciences of the Saint-Petersburg State Medical Academy

08_900 © O.A.Vetkina, N.A.Karlova, I.V.Polyakov, 2008

UDC: 614.2:616-073.75Vetkina O.A, Karlova N.A., Polyakov I.V. Paramedical personnel of radial diagnostic

department as potential managers // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 32-35.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y : Performed examination shows the necessity of the serious preparation of real and potential leaders on different questions of management. Their positions are very strong in strategic leadership, positive approach to innovations appropriate knowledge of professional problems and good relations with colleagues. The analysis revealed that great part of workers have the potential of leaders, they are sure that they are very responsible and can rule the collective and find the approaches in various conflict situations. As we detected, the most part of such persons are younger than 40 years old. In examined collectives there were all the possibilities for realization of democratic leadership but such a invention should be slow and careful as some of the workers need serious control. At present time there is important that leader would discuss with workers not only today’s tasks but also strategic plans and possible results, involving all the workers in the ruling process. Leaders must be more active in financial stimulating of workers and also moral stimulation, what is of serious importance for personnel.

K e y w o r d s : nurse, middle medical personnel, radio diagnostics, manager of the middle medical personnel, management, leader

I n f o r m a t i o n a b o u t t h e a u t h o r s : Vetkina Olga Alekseevna – senior nurse of the Roentgenologic Department of the State

Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy», 195067, St.-Petersburg, Piskarevsky prospect, 47, tel./fax: 8-812 5452398, 8-812 5454893, е-mail: vetkina58@ru

Karlova Nataliya Alexandrovna – doctor of medicine, professor, head of the Department of Radiodiagnostics and Radiotherapy of the State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy», 195067, St.-Petersburg, Piskarevsky prospect, 47, tel./fax: 8-812 5452398, 8-812 5430013, е-mail: [email protected]

Polyakov Igor Vasilievich – doctor of medicine, professor, academician of MANEB, honored scientist of the Russian Federation, head of the Course of Management and Economics of Public Health of the State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy», 195067, St.-Petersburg, Piskarevsky prospect, 47, tel./fax: 8-812 7401524, е-mail: [email protected]

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09_879 © V.I. Svidovyi, L.A. Karaseva, K.A. Matveeva, 2008

UDC: 614.2-056.266/.267Svidovyi V.I., Karaseva L.A., Matveeva K.A. Labour employment of invalids at regional

level // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 35-40.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]: [email protected]; www.mechnik.spb.ru

S u m m a r y : In the article of Karassaeva L.A., Matveeva K.A., Svidovoy V.I. "State of labour employment of disabled people on regional level" (according to material of placement service activity in St.-Petersburg) is given the analysis of condition of vocational rehabilitation on regional level on example of St.-Petersburg. The article describes general directions of placement service (PC) activities by job placement of disabled people, analyses comparative social-hygienic of citizens and disabled people kept in a record in PC and examines the dynamics descriptions of job placement and vocational training of disabled people over 12 years (1994-2005). There is showed in the article that efficiency of job placement of disabled people depends on complex problem-solving.

K e y w o r d s : invalids, social-hygienic characteristics, employment.I n f o r m a t i o n a b o u t t h e a u t h o r s :Svidovyi Vasily Ivanovich – doctor of medicine, professor of the Department of Hygiene

of the Surrounding and Industrial Environment, head of the course of Hygiene of Labor of the Mechnikov Saint-Petersburg State Medical Academy, work tel., 544-92-98; local tel.: 516; mobile tel.: 8-921-776-12-50.

Kasareva Lyudmila Alekseevna – candidate of medical sciences, assistant-professor of the Department of MSE and Rehabilitation of Invalids of the Federal State Establishment «Saint-Petersburg Institute for Advanced Training of Physician-experts of Roszdrav», work tel.: 541-86-02; mobile tel.:8-905-206-91-17.

Matveeva Klavdiya Alexandrovna – head of the Committee for the Employment of Population of the Administration of Saint-Petersburg.

MOTHER AND CHILDHOOD PROTECTION

10_1050 © A.G. Sukharev, A.A. Baranov, V.G. Maimulov, 2008

UDC: 614.2-053.2/.6Sukharev A.G 1, Baranov A.A.2, Maimulov V.G.3 Prophylactic principles of national

projects development in the field of public health services in the interest of children // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 40-48.

1State educational establishment for higher professional training «Russian Medical Academy for Post-Diploma Training», Russia, 123836, Moscow, Barrikadnaya str., h. 2. phone: 8(495)252-21-04, fax: 8(495)254-98-05/

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2State scientific institution «Scientific Center for Children Health» of the Russian Academy of Medical Sciences, Russia, 119361, Moscow, GSP-1 Lomonosovskyi pr. 2/62, phone: 8(495)134-30-83.

3State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; www.mechnik.spb.ru

S u m m a r y . Considering studies of special characteristics of children population health state in the Russian Federation in interrelation with environment factors it is stressed, that preventive direction and strengthening of children and teenagers health is a priority process in the development of the national project in public health services. This process consists of actions directed on favorable social and economic changes in the country, and on the protection of the environment and modernisation of public health services and formation for the aim of improvement of their influence on the health of the rising generation.

K e y w o r d s : social and economic changes in the country, protection of the environment, modernisation of public health services, formation for the aim of improvement, children population health state.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Sukharev Alexander Grigorievich – Academician RAMS, Honoured Scientist RF, Doctor

of Medicine, Professor, head of the вepartment of Hygiene of Children and Adolescents SEEHPT «Russian Academy for Post-Diploma Training», Russia, Moscow,

Baranov Alexander Alexandrovich – Academician RAMS, Honoured Scientist of RF, Doctor of Medicine, Professor, director of the state scientific institution «Scientific Center for Children Health» of the Russian Academy of Medical Sciences, Russia, Moscow,

Maimulov Valery Georgievich – Honoured Scientist of RF, Doctor of Medicine, Pro-rector for research work, head of the department of Preventive Medicine and Health Protection of the Faculty for Advanced Professional Training of SEEHPT «Saint-Petersburg State Medical Academy named after I.I.Mechnikov»

11_863 © F.I. Salomova, 2008

UDC: 616-056.5-053.5Salomova F.I. Feature of physical development of schoolchildren with posture

disturbances // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 48-51.

Tashkent Medical Academy, Uzbek Republic, 100109, Tashkent, Farobi str., 2, tel..: +998-(71)-150-78-25; +998-(71)-114-83-11, fax: +998-(71)-118-59-48, e-mail: [email protected]; [email protected]; [email protected], www. tma.uz

S u m m a r y : To create presentation about bearing state in contemporary children and teenagers 2125 schoolchildren of the Uzbek nationality of the grades 1-9 have been examined. Analysis carried out of the bearing state exhibited an availability of one or some signs of bearing disorders in the majority of schoolchildren. Features of physical development in children with bearing disorders were characterized by signs of higher level in height and dysharmonicity - by body mass. It was revealed that accelerated growth and asthenic type of constitution often leads to bearing disorders. It should be consider an age 7-8 and 10-11 for girls, 7-9 and 11-12 for boys as critical aging periods for formation of bearing, when risk of developing bearing disorders was increasing. It should be take into consideration in organization of preventive measurements.

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K e y w o r d s : physical development, schoolchildren of Uzbek nationality, disorders of posture.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Salomova F.I.- Tashkent Medical Academy, Uzbek Republic, 100109, Tashkent, Farobi

str., 2, tel..: +998-(71)-150-78-25; +998-(71)-114-83-11, fax: +998-(71)-118-59-48, phone home: +998-(71)-118-38-46, phone mob.: +998-(71)-104-18-36. e-mail: [email protected]; [email protected]; [email protected], www. tma.uz

12_1010 © E.M. Cherkasova, 2008

UDC: 618.1:616-053.5:613.8Cherkasova E.M. Characteristics of somatic and reproductive health of girls from risk

group // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 51-54.

State Educational Establishment of Higher Professional Training “Saint-Petersburg State Pediatric Medical Academy of the Federal agency for health services and social development of the Russian Federation», Russia, 194100, Saint-Petersburg, Litovskaya str. 2; phone (812)295-06-46; fax (812)295-40-85; e-mail: [email protected], http://www.gpma.ru.

S u m m a r y . The analysis of 2310 Saint-Petersburg street girls’ somatic and reproductive health was carried out. Almost all of them have significant disturbances. That’s why this group of children needs serious social, medical and psychological help.

K e y w o r d s : girls’ somatic and reproductive health; street children; Saint-Petersburg.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Cherkasova Elena Mikhailovna, Candidate of Medical Sciences, Senior Teacher of the

department of Humanities and Bioethics of SEEHPT «Saint-Petersburg State Medical Academy named after I.I.Mechnikov of ROSZDRAV»

13_986 © E.V. Izvekova, 2008

UDC: 613.2:618.2Izvekova E.V. Evaluation of nutritional status of pregnant women // Herald of the

Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 54-57.State educational establishment for higher professional training “Orel State Institute of

Economics and Trade” of the Minister of Education and Science of the Russian Federation, Russia, 302028, Orel, Oktyabrskaya str., 12, tel./fax (4862) 43-51-63, E-mail: [email protected], [email protected]

S u m m a r y . Food status of 97 pregnant women living in Orel has been recently investigated. It has been found out that most women investigated at the beginning of their pregnance suffer from weight loss in comparison with their weight before pregnance. Laboratory criteria of food status of 75 per cent of pregnant women correspond to the standard. Their general weight increase is about 11,46±3,75 kg that corresponds to the recommended norm.

K e y w o a r d s : food status, pregnant womenI n f o r m a t i o n a b o u t t h e a u t h o r s :

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Izvekova E.V. – teacher, Russia, 302030 Orel, Polikarpov str., 10, apt. 2, work tel.: 8(4862) 43-32-88, home tel.: 8(4862) 55-70-98, mobile phoneтел.моб.: 80920-285-97-60, E-mail: [email protected]

14_825 © L.V. Talykova, 2008

UDC: 614.2:616-053.31Talykova L.V. Influence of risk factors associated with mathor’s health on the

development of pathological conditions in perinatal period in newborns // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 57-60.

Research Laboratory, Federal State Institution for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor of the Russian Federation», Murmansk region, 184250, Murmansk region, Kirovsk, Lenin prospect, 34, tel.: (815-31) 91144, fax: (815-31) 91174, e-mail: [email protected]

S u m m a r y : Analysis of development of separate pathological conditions of perinatal period (SPCPP) in 25 688 newborns revealed various degree of influence of non-occupational risk factors to which their mothers were exposed. The highest risk for developing SPCPP was associated with excessive use of alcoholic drinks (OR=2,72), misuse of pharmacologic drugs such as hormones and antibiotics (OR=2,43), and tobacco smoking (OR=1,46).

K e y w o r d s : pathologic state of newborn perinatal period, risk factors: alcohol use, drugs (hormones and antibiotics), mother’s smoking.

15_1022 © N.Ju. Katkova, N.А Mariyamova, V.V. Malyshev, M.G. Romantsov, 2008

UDC: 618.36:577.121.7Katkova N.Yu.1, Mariamova N.A.1, Malyshev V.V.1, Romantsov M.G2. Antioxidant status

study in pregnant women with fetoplacental insufficiency from risk group of intrautenine fetus infection // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 60-64.

1Nizhny Novgorod State Medical Academy, Russia, 603600, Nizhny Novgorod, Minin and Pozharsky Square, 10/1, tel.: 8-381-239-09-43.

2Scientific-Technological Pharmaceutical Firm “POLYSAN”, Russia, 191119, Saint-Petersburg, Ligovsky prospect, 112, tel.: 8(812)110-82-25,112-13-79, е-mail: [email protected], STPF “POLYSAN” www.polysan.ru

S u m m a r y . Anti-oxidative state of 35 pregnant women with fetoplacental dysfunction from a group of patients vulnerable to intrauterine infection was studied and the efficacy of Reamberin during combined therapy of fetoplacental dysfunction was evaluated. We have performed an examination of condition of anti-oxidative protection system, lipid peroxidation, ultrasonic fetometry and placentography, and Doppler imaging. Сombined therapy with Reamberin resulted in increase of total anti-oxidative activity by 30% (p<0.05), improvement of blood flow parameters in fetal-uteroplacental vessels (according to resistance index in umbilical cord artery).

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K e y w o r d s : antioxidant status of pregnant women, fetoplacental insufficiency, reamberin

I n f o r m a t i o n a b o u t t h e a u t h o r : Romantsov Mikhail Grigorievich – Doctor of Medicine, Professor of the department of

Infectious Diseases of SEEHPT Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav

HYGIENE OF THE SURROUNDING AND INDUSTRIAL ENVIRONMENT

16_1030 ©V.G. Artamonova, O.N. Basova, O.V. Shvalev, E.B. Kolesova, 2008

UDC: 613.62:691:614.2Artamonova V.G., Basova O.N., Shvalev O.V., Kolesova E.B. The evaluation of

occupational patients of the construction materials industry Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 64-68.

Mechnicov Sant-Petersburg State Medical Academy, 195067, St-Petersburg, Piscarevsky avenue, 47

S u m m a r y : The analysis if the new rehabilitation system of occupational workers of the modern construction materials industry was made. It was studied the new medical treatment and rehabilitation influence. It was made the analysis of the rehabilitation efficiency in 151 occupational patients.

K e y w o r d s : rehabilitation, occupational patients, the rehabilitation efficiency, the construction materials industry.

I n f o r m a t i o n a b o u t t h e a u t h o r s :Artamonova V.G. - academician of RAMS, doctor of medicine, professor, work tel.:543-

06-20Basova O.N. – post-graduate students, assistant of the department of occupational

medicine, mobile phone 8-911-252-07-17, home tel.:744-86-19Shvalev O.V. – candidate of medical science, assistant-professor of the department of

occupational medicine, work tel.:543-93-20Kolesova E.B. - candidate of medical science, assistant-professor of the department of

occupational medicine work tel.: 543-93-20

17_913 © E.V.Zibarev, S.M.Nikonova, M.V. Chashchin, I.I.Pochkarev, N.V.Zakharova, 2008

UDC: 613.63:614.2(571.651)Zibarev E.V., Nikonova S.M., Chashchin M.V, Pochkarev I.I., Zakharova N.V. Concept of

risk reduction of harmful effects of toxic substances on the body of aboriginal population of Chukotsky Autonomous Okrug // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 68-71.

Federal State Institution for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor of the Russian Federation», 191036, St.-Petersburg, 2

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Krasnoarmeyskaya, 4, tel.: 8-812-717-97-54, fax: 8-812-717-02-64, e-mail: [email protected]

S u m m a r y : The article proposes measures that are focused on search, identification, collection and recycling of local sources of pollution (contamination), by means of the sanitary situation improvement and detoxication of uncontrolled waste dumps in the villages Lavrentia and Lorino located in Chukotka Autonomous District.

For the first time in long-term history, on the initiative of the local residents, a work on clearing these settlements’ territory from toxic waste has been started. High level of public concern and the readiness of the local residents to start works on clearing the contaminated territory allowed to select volunteers among the local residents and to teach them safe handling of the toxic substances.

K e y w o r d s : consistent toxic substances, risk reduction of the negative impact, Сhukotka autonomous district inhabitants.

I n f o r m a t i o n a b o u t t h e a u t h o r :Zibarev E.V. – candidate of medical sciences, researcher of the Federal State Institution

for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor», 191036, St.-Petersburg, 2 Sovetskaya str., 4, tel.: 8-812-717-97-54, fax: 8-812-717-02-64, mobile phone: 8-921-953-02-73, e-mail: [email protected]

Chashchin MaximValerievich – doctor of medicine, researcher of the Federal State Institution for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor», 191036, St.-Petersburg, 2 Sovetskaya str., 4, tel.: 8-812-717-97-54, fax: 8-812-717-02-64, mobile phone:

18_823 © V.I. Svidovyi, I.M. Akhmetzyanov, V.N. Zinkin, M.S. Nikolaevich, E.E. Palishkina, I.R. Gazizova, 2008

UDC: 613.644Svidovyi V.I.1, Akhmetzyanov I.M.2, Zinkin V.N.1, Nikolaevich M.S.1, Palishkina E.E.1,

Gazizova I.R.1 Urgent problems of acoustic influence // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 71-74.

1State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

2General Court of Saint-Petersburg, Saint-Petersburg, RussiaS u m m a r y : The decision of a problem of health protection of the persons, influence

noise and an infrasound, is possible at perfection of hygienic standardization. The basic directions of it are: an estimation of risk; verify of character of frequency dependence of biological effects; development of new methods of dosimetry with use of variable value of exchange rate.

K e y w o r d s : influence noise and an infrasound, hygienic standardization.

19_949 © T.E. Lim, 2008

UDC: 613.6:677

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Lim T.E. Some aspects of organization of social-hygienic monitoring system in construction and exploitation of bypass roads (CAR), Petersburg as an example // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 74-77.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y : Social-hygienic monitoring (SHM) is an integral part of the environmental and health management. Analytical materials collected in the course of SHM and population health risk assessment serve as a ground for management decision-making. SHM in the course of construction of the ring road means identification of quantitative and qualitative changes of the environment with time. Only systematic and thoroughly planned observations give an opportunity to identify the nature and trend of such changes by connecting them with major adverse factors of construction.

K e y w o r d s : environment, roundabout highways, system of socially-hygienic monitoring.

I n f o r m a t i o n a b o u t t h e a u t h o r :Lim Tatiyna Evgenievna – candidate of medical sciences, assistant of the Department of

the general, military, radiating hygiene and medical ecology SPbGMA I.I. Mechnikov, work tel.: (8-812) 543-17-55 hom.: (8-812) 368-91-87, mobil.: 8-9110233580, E-mail:[email protected].

20_859 © G.A. Bezrukova, L.D. Gromova, V.F. Spirin, 2008

UDC: 613.6:621.039:615.357Bezrukova G.A., Gromova L.D., Spirin V.F. Thyroid system state in allergenic

dislipidemia in the personnel of atomic power stations working in conditions of radiation doses // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 77-81.

Saratov Research Institute of Rural Hygiene of Rospotrebnadzor, 410022, Saratov, Zarechnaya str., 1–А, tel./fax: 8(845-2)92-78-90, tel.: 92-34-94, e-mail: [email protected]

S u m m a r y : Healthy atomic electric power station workers with irradiation doses were examined. It was revealed that high level of the blood lipid risk factor for atherosclerosis don’t accompanied by T3─low syndrome, as a typical ischemic heart disease sign. Compensatory increase thyrotrophic activity and speed up the process of thyroid hormones peripheral transformation initiated by prolonged professional effect of radiation influence was shown.

K e y w o r d s : dose loads, atomic power plant personnel, atherogenic dislipidemia, thyroid maintaining systems.

I n f o r m a t i o n a b o u t t h e a u t h o r :Bezrukova Galina Alexandrovna 410600, Saratov, Volskaya str., 32/34, apt. 13, work

tel.: 8(845-2)92-34-94, home tel.: 8(845-2)27-28-08, fax: 8(845-2)92-78-90, e-mail: [email protected]

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NEW TECHNOLOGIES, METHODS OF DIAGNOSTICS, TREATMENT AND PREVENTION IN PUBLIC HEALTH SERVICES

21_857 © A.E. Sukharev, T.N. Yеrmolaeva, N.A. Beda, V.Ju. Tegza, 2008

UDC: 616-074:543/545:612.313.1Sukharev A.E., Yermolaeva T.N., Beda N.A., Tegza V.Yu. Organisation of

immunochemical saliva lactoferrin studies for the evaluation of health // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 81-85.

1Astrakhan Regional Public Institution of Humanitarian Problems «GRANT», 414000, Astrakhan; Krasnaya Embankment, 7.

2Kirov Military Medical Academy, 194044, Saint-Petersburg, Lebedeva str. 6, tel.: 8-812-329-71-02.

S u m m a r y : The lactoferrin is detected in common saliva of 1026 patients and 1426 relative health people of several social groups by immunodiffusion methods. Its levels increase have patients with respiratory, digestive diseases, diabetes and industrial workers with ecological bad conditions of labor. We conclusion, that immunochemical lactoferrins test is perspective for dispensary screening and monitoring of health estimation. (The science project № 07-06-00617a, support by Russian Humanitarian Science Fond).

K e y w o r d s : mixed saliva, immunodiffusion analysis, lactoferrin, respiratory organ diseases, digestion, diabetes, industrial workers, healthy persons.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Sukharev Alexander Evgenievich - doctor of medicine, head of the Astrakhan Scientific

Regional Public Institution of Humanitarian Problems «GRANT», 414041, Astrakhan, Gerasimenko str., 2, apt.63.

Tegza V.Yu. – doctor of medicine, professor, medical colonel, head of the Department of Public Health and Economics of Military Health of Kirov Military Medical Academy, St.-Petersburg

22_915 © Е.А. Korymasov, O.V. Tyumina, A.M. Ayupov, A.V. Kazantsev, V.A. Rossiev, G.V.Micheev, S.E.Volchkov, A.N.Toropovskiy, 2008

UDC: 616.718-08:616-004.6Korymasov Е.А.¹, Tyumina O.V.³, Ayupov A.M.², Kazantsev A.V.², Rossiev V.A.², Micheev

G.V.², Volchkov S.E.³, Toropovskiy A.N.³ Method of neoangiogenesis stimulation in patients with distal form of obliterating lower extremities atherosclerosis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 85-88.

¹State educational establishment for higher professional training «Samara State Medical University of the Federal Agency for Public Health and Social Development» (SEE SamSMU Roszdrav) 443099, Samara, Chapaevskaya str., 89, tel../fax:8(846)332-16-34, 333-29-76, е-mail: [email protected]

²State institution of public health services of Samara region «Samara Regional Clinical Hospital named after M.I.Kalinin», department of Vascular Surgery

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³State institution of public health services of Samara region «Clinical Center for Cellular Technologies», Samara

S u m m a r y . The results of neoangiogenesis has been studied for the treatment of 42 patients with lower arterial atherosclerosis occlusive disease. We studied the results in the 3 groupies including 14 patients in the each. Autological progenitor cells (CD133+) were transplanted in I group. Leucocytes bone morrow cells were transplanted in II group. The patients of III group was injected isotonic solution as a placebo.

K e y w o r d s : arterial atherosclerosis occlusive disease, neoangiogenesis.I n f o r m a t i o n a b o u t t h e a u t h o r s : Korymasov Evgeny Anatolievich – head of the department of Clinical Surgery of the

institute for Post-Diploma Training of Samara State Medical University, Doctor of Medicine, Professor. Address for correspondence: 443 079 Samara, Gagarin str., 37, apt. 34, Prof. Korymasov E.A. tel. 8(846) work 956-22-72, home 264-80-14, mobile phone 8-927-608-00-41, fax 956-15-16, e-mail: [email protected]

Tyumina Olga Vladimirovna – director of the clinical center for Cellular Technologies, Candidate of Medical Sciences.

Kazantsev Alexander Victorovich – angiosurgeon of the department of Vascular Surgery of Samara Regional Clinical Hospital named after M.I.Kalinin, Candidatye of Medical Sciences.

Rossiev Victor Anatolievich – head of the department of Hematology and Bone Marrow Transplantation of Samara Regional Clinical Hospital named after M.I. Kalinin, Candidate of Medical Sciences.

Ayupov Amir Minakhmetovich – deputy chief physician for surgery of Samara Regional Clinical Hospital named after M.I.Kalinin, Candidatye of Medical Sciences.

Mikheev Gennadiy Victorovich – head of the department for Vascular Surgery of Samara Regional Clinical Hospital named after M.I.Kalinin.

Volchkov Stanislav Eugenievich – deputy-director for quality control of the Clinical Center of Cellular technologies, physician of clinical laboratory diagnostics.

Toporovsky Andrey Nikolaevich – physician of the laboratory for Immunological Typing of the Clinical Center of Cellular Technologies.

23_926 © T.F. Fiodorova, M.J. Melnikova, L.J. Vinogradova, E.N. Zinoveva, A.R. Dmitrieva, L.R. Tarkovskaja, L.P. Papajan

UDC: 616-007.17:[616.831+616.36]:616-056.5:546.56

Fiodorova T.F., Melnikova M.Yu., Vinogradova L.Yu., Zinivieva E.N., Dmitrieva A.R., Tarkovskaya L.P., Papayan L.P. Influence of copper metabolism disorder on the intravascular platelets activation in patients with hepatocerebral dystrophy // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 88-92.

The Saint-Petersburg State Medical Academy named after I.I.Mechnikova. Russia, 195067, Saint-Petersburg, Piscarevskyi prospect, 47, phone: (812)543-93-18, a fax: (812)740-15-24, e-mail: [email protected]

The Russian Scientific Research Institute of Hematology and Transfusiology Federal public institution on hi-tech medical aid. Russia, 191024, Saint-Petersburg, street 2-nd Sovietskaya, 16, phone: 8-812-274-56-50, a fax: (812 717-25-50, a fax 812 (274-92-27) e-mail: [email protected] and [email protected]

S u m m a r y . The article represents the data on studying intravascular activation of platelets and parameters of abnormal copper metabolism at 39 patients with hepatocerebral dystrophy (Wilson disease). Control group consists of 25 healthy people. Data about influence

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hypoceruloplasminemia and hypocupremia on quantity and aggregation of platelets, a level of free copper in blood – on activation of platelets in blood are obtained. At patients with hepatocerebral dystrophy the factor promoting development of quantitative and qualitative abnormalities of platelets, is abnormal copper metabolism.

K e y w o a r d s : Hepatocerebral dystrophy (Wilson disease), abnormal copper metabolism, platelets.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Feodorova Tamara Fedorovna, Candidate of Medical Sciences, Assistant-Professor of the

department of Neurology, Neurosurgery and Medical Genetics. Saint-Petersburg State Medical Academy named after I.I.Mechnikov of the Federal Agency for Public Health and Social Development SEE SPSMA named after I.I.Mechnikov of Roszdrav. Russia, 195067, Saint-Petersburg, Piskarevsky prospect., 47, tel.: 8-812-543-00-73; fax: 8-812-543-01-26; е-mail: [email protected]; mobile phone: 7-911-988-50-66.

Melnikova Mariya Yurievna, 6-th year student of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov. е-mail: [email protected]

Vinogradova Lyudmila Yurievna, Candidate of Medical Sciences, assistant of the department of Neurology, Neurosurgery and Medical Genetics. Saint-Petersburg State Medical Academy named after I.I.Mechnikov of the Federal Agency for Public Health and Social Development SEE SPSMA named after I.I.Mechnikov of Roszdrav. Russia, 195067, Saint-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-00-73; fax: 8-812-543-01-26; е-mail: [email protected]

Zinovieva Eugenia Nikolaevna, Candidate of Medical Sciences, Assistant-Professor of the department of Internal Diseases with the course of Therapy and Nephrology of the Faculty for Advanced Doctors Training. Saint-Petersburg State Medical Academy named after I.I.Mechnikov of the Federal Agency for Public Health Social Development SEE SPSMA named after I.I.Mechnikov of Roszdrav. Russia, 195067, Saint-Petersburg, Piskarevsky prospect, 47. tel.: 8-812-543-05-75; fax: 8-812-543-05 -90; е-mail: [email protected]

Alisa Rafaelovna Dmitrieva, full-time post-graduate student. Federal State Institution “Russian Research Institute for Hematology and Transfusiology” of the Federal agency for high-technological medical aid. Russia, 191024, Saint-Petersburg, 2-nd Sovietskaya str.,16, tel.: 8-812-274-56-50, fax: 8-812- 717-25-50, факс 8-812 -274-92-27; tel. of laboratory for blood clotting 8-812-717-35-82; е-mail: [email protected]

Tarkovskaya Lana Rostislavna, Candidate of Biological Sciences, researcher of the laboratory for Blood Clotting. Federal State Institution “Russian Research Institute for Hematology and Transfusiology” of the Federal agency fjr high-technological medical aid. Russia, 191024, Saint-Petersburg, 2-nd Sovietskaya str.,16, tel.: 8-812-274-56-50, fax: 8-812- 717-25-50, факс 8-812 -274-92-27; tel. of laboratory for blood clotting 8-812-717-35-82; е-mail: [email protected]

Papaya Lyudmila Petrovna, Professor, Doctor of Medicine, head of the laboratory for Blood Clotting. Federal state institution “Russian Research Institute for Hematology and Transfusiology” of the Federal agency for high-technological medical aid. Russia, 191024, Saint-Petersburg, 2-nd Sovietskaya str. 16, tel.: 8-812-274-56-50, fax: 8-812- 717-25-50, fax 8-812 -274-92-27; tel. of laboratory for blood clotting: 8-812-717-35-82; е-mail: [email protected]

24_896 © V.N. Fedorets, I.V. Vologdina, E.G. Poroshina, O.N. Simonova, 2008

UDC: 616.12:616-005.4:616.8-009:616-053.9

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Fedorets V.N. 1, Vologdina I.V. 2, Poroshina E.G. 3, Simonova O.N. 2

Psychosomatic features of patients of an old age with ischemic heart disease complicated by chronic heart failure // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 92-97.

1State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

2Federal State Establishment «Federal State Institution RSC RHT Rosmedtechnology», St.-Petersburg

3State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 191015, Kirochnaya str., 41, tel.: 272-52-06, fax: 273-00-39, e-mail: [email protected]

S u m m a r y : Clinical symptoms, quality of life and personality disorders were studied in 71 elderly patients aged 75-84 suffering from ischemic heart disease and chronic heart failure of NYHA class III. Patients were divided on 2 groups being depended on personality disorders. Depressive symptoms were revealed in 56% of patients. Multiple regression analysis showed that clinical symptoms were consistently and closely associated with depressive symptoms and quality of life

K e y w o r d s : depression, congestive heart failure, elderly patient I n f o r m a t i o n a b o u t t h e a u t h o r s :Fedorets Victor Nikolaevich – assistant-professor of the Department of Internal Diseases

with the Course of Therapy, Nephrology of the Faculty of Advanced Training of Mechnikov Saint-Petersburg State Medical Academy

Vologdina Irina Vladislavovna – leading researcher of the Laboratory of Nuclear Cardiology of the Federal State Institution RSC «RHT Rosmedtechnology»

Poroshina Elena Grigorievna – assistant-professor of the Department of Therapy and Clinical Pharmacology of the Saint-Petersburg Medical Academy for Post-Diploma Training

Simonova Olga Nikolaevna – head of the Laboratory of Nuclear Cardiology of the Federal State Institution «RHT Rosmedthechnology»

25_895 © S.V. Azanchevskaya2, V.P. Novikova2, V.Ph. Ivanova1, 2008

UDC: 616.33-002.2-053.2/.6:611-018Azanchevskaya S.V. 2, Novikova V.P. 2, Ivanov V.F. 1 Morphological and ultrastructural

features of autoimmune gastritis in children // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 97-100.

1State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

2State Educational Establishment of Higher Professional Training «Sankt-Petersburg state pediatric academy of the Federal Agency for Public Health and Social Development of the

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Russian Federation», 194100, St.-Petersburg, Litovskaya str., 2, tel. (812)542-39-83, tel./fax: (812)295-40-85, e-mail: [email protected]

S u m m a r y : 25 biopsies from children suffering from chronic autoimmune gastritis and 54 biopsies from children suffering from chronic gastritis with another etiology were examined by histological method. Antibodies to к Н+К+/АТФ-аsе were determined by cerological method.3 biopsies from seropositive patients and 1 biopsy from seronegative patient were examined by electronic microscopy method.

Preatrophic and atrophic changes and disturbance of mucosal microcirculation at fundal biopsies from seropositive patients were founded.

Some ultrastructural abnormalities of parietal cells and plasmocytes were founded too. K e y w o r d s : Н+К+/АТFase antibodies, autoimmune gastritis, morphological and

ultrastructural features.I n f o r m a t i o n a b o u t t h e a u t h o r s :Azanchevskaya Svetlana Vladimirovna- candidate of medical sciences, assistant-

professor of the Department of Pathological Anatomy. Mechnikov Saint-Petersburg State Medical Academy.195067, St.-Petersburg, Piskarevsky prospect, 47, fax: (812) 740-15-24, e-mail: [email protected]

Novikova Valeria Pavlovna, candidate of medical sciences, assistant-professor of the Department of Propedeutics of Children Diseases with the course of General Care for Children. Saint-Petersburg State Pediatric Medical Academy. 194000, St.-Petersburg, Litovskaya str., 2, tel.: (812) 556-53-14, e-mail: novikova-vp@mail. ru

Ivanov Alexander Vladimirovich, candidate of medical sciences, assistant of the Department of Propedeutics of Children Diseases with the course of General Care for Children. Saint-Petersburg State Pediatric Medical Academy. 194000, St.-Petersburg, Litovskaya str., 2, tel.: (812), e-mail: [email protected]

26_940 © E.G. Topuzov, G.A. Shishkina, E.E. Topuzov, Z.A. Medzhidov, A.G. Danilov

UDC: 616.35-006-089:616.352Topuzov E.G., Shishkina G.A., Topuzov I.I., Medzhidov Z.A., Danilov A.G. Sphincter

spraring operations in early stages of rectal cancer with low localization // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 100-103.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y . 105 (40%) patients from 260 have been made sphincterconservation operations at a cancer of a rectum of low localization. Use of own updating of operations, and also keeping of indications and conditions of their performance was accompanied by a lethality of 4%, frequency of postoperative complications of 15%, five years' survival rate of 64%.

K e y w o r d s : cancer of a rectum, Surgical treatment with conservation of the sphincter apparatus.

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27_996 © K.S. Berishvili ,N.E. Ivanova, T.O. Izvekova, V.V. Unzhakov, 2008

UDC: 616.833.34-089:615.831Berishvili K.S., Ivanova N.E., Izvekova T.O., Unzhakov V.V. Effects of radiation dark blue

special in surgical treatment on damaged nerves // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 103-106.

Russian Research Neurosurgical Institute named after prof. A.L. Polenov of Russian Medical Technologies, Russia, 191014, St.-Petersburg, Mayakovsky str., 12, tel./fax: 272-98-79, e-mail: [email protected]

S u m m a r y . Results of clinical application of radiation dark blue special on damaged nerves at 138 patients are submitted. Reduction of terms of the regenerative period, precise regulation of parameters of influence- specifies all this perspectivity of use given method in neurosurgery.

K e y w o a r d s : brachial plexus, radiation dark blue special, peripheral nerves.I n f o r m a t i o n a b o u t t h e a u t h o r s :Berishvili K.Sh., FSI Russian Research Neurosurgical Institute named after A.L.Polenov,

physician-neurologist, post-graduate student, Mayakovsky str.,12, tel.: 8-921-400-86-05, email: [email protected]

Ivanova N.E., Doctor of Medicine, Professor, FSI Russian Research Neurosurgical Institute named after A.L.Polenov, physician-neurologist, post-graduate student, Mayakovsky str.,12, tel.: 89112187149

Izvekova T.O., Candidate of Medical Sciences, FSI Russian Research Neurosurgical Institute named after A.L.Polenov, physician-neurologist, post-graduate student, Mayakovsky str.,12, tel., телефон 89117654058

Unzhakov V.V., Candidate of Medical Sciences, FSI Russian Research Neurosurgical Institute named after A.L.Polenov, physician-neurologist, post-graduate student, Mayakovsky str.,12, tel.: 89062643332

28_1038 © F.A. Tsimbal, A.V. Golubkov, A.V. Kuzmin, N.V. Steinberg

UDC: [616.–07:614.2]:[615.9:534.632.585]Tsimbal F.A.1, Golubkov A.V.2, Kuzmin A.V.2, Steinberg N.V.1 Complex use of

papillometry and determination of cholenasteraze activity to reveal affection by toxic chemicals of anticholinesterase activity // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 106-110.

1Research Institute of Hygiene, Occupational Pathology and Human Ecology Federal Unitary Enterprise, Federal Medical Biological Agency (FGUP «NII GPECh» FMBA Rossii), build. 93, Kapitolovo Station, g/p Kuz’molovskii, Vsevolozhskii District, 188663 Leningrad Region, tel/fax (812) 449-61-77; (812) 449-61-68; (813-70) 92-439, E-mail: [email protected]; [email protected]

2Northwest Research Center for Hygiene and Public Health of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being Federal State Science Enterprise, 4 2 Sovetskaya Str., St. Petersburg, tel (812) 717-97-54, fax (812)717-02-64, E-mail: [email protected]

S u m m a r y : A scheme for the establishment of exposure to toxic chemicals with anticholine esterase activity, using a combination of pupillometry and Blood Choline Esterase

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Activity Assessment is suggested, and an analysis of mistakes in the automated diagnosis of the exposure is given. Step-by-step testing of the operational algorithm of the system is performed to demonstrate its performance.

K e y w o r d s : toxic chemicals, pupillometry, blood choline esterase, automated diagnosis.

I n f o r m a t i o n a b o u t t h e a u t h o r s :Tsimbal Fedor Anatolyevich – Dr. B. Sci, head of Laboratory of Research Institute of

Hygiene, Occupational Pathology and Human Ecology Federal Unitary Enterprise, Federal Medical Biological Agency, tel/fax (812) 449-61-77; (812) 449-61-68; (813-70) 92-439, E-mail: [email protected]

Golubkov Alexandr Vasilyevich – scientific colaborator of Northwes t Research Center for Hygiene and Public Health of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being Federal State Science Enterprise, tel. (812) 717-97-54

Kuzmin Alexei Victorovich – candidate of medical sciences, scientific colaborator of Northwes t Research Center for Hygiene and Public Health of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being Federal State Science Enterprise, tel. (812) 717-97-54

Steinberg Natalya Vladimirovna – scientific colaborator of Research Institute of Hygiene, Occupational Pathology and Human Ecology Federal Unitary Enterprise, Federal Medical Biological Agency, tel/fax (812) 449-61-77; (812) 449-61-68; E-mail: [email protected]

CLINICAL AND EXPERIMENTAL STUDIES

29_914 © V.V. Naumova, E.S. Zemtsova

UDC: 616.1:616-053.84/.86Naumova V.V., Zemtsova E.S. Slow-wave variability of vascular circulation in mature age

// Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 110-114.

S u m m a r y . The analysis of the variability of aortic pulse amplitude (APA) and microvascular pulse amplitude (MPA) of great toe has been performed in apparently healthy men and women aged 35-55 years. Power spectral analysis of APA variability showed the prevalence of high-frequency (HF) oscillation range (0,15-0,5 Hz) associated with respiration; and the prevalence of very low-frequency (VLF) oscillation (0,025-0,075 Hz) in MPA variability, which was found to be the marker of humoral-metabolic regulation. There were found gender related specifications of absolute and relative indices of vascular pulse variability.

K e y w o r d s : Slow-wave variability, vascular circulation, mature age.I n f o r m a t i o n a b o u t t h e a u t h o r s : Naumova V.V., Candidate of Medical Sciences, Assistant-Professor of the department of

Clinical and Medical-Social Examination SEEAPT NSIADT of Roszdrav Zemtsova E.S., senior researcher of the laboratory for Occupational Pathology, employee

of the laboratory of Occupational Pathology of the research institute KPG PZ SO RAMS

30_919 © O.V. Amelina, L.A. Sokolova, I.I. Dubovoy, 2008

UDC: 616.12-008.331.1:614.8

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Amelina O.V.1, Sokolova L.A.1, Dubovoy I.I.2 Special features of arterial hypertension in fighters of accident in Chernobyl atomic power plant // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 114-118.

1 St. Petersburg State Medical Academy named after I. I. Mechnikov, Piskarevsky p., 47 195067 Saint Petersburg. tel. (8-812)-543-59-18,эл.почта: mechnik@ gmail . com ; mechnik @westcall.net ; www.mechnik.spb.ru

2 Municipal Healthcare Facility “City polyclinic №5”, 99 Moskovsky pr. 241004 Bryansk tel. (8-4832)-63-03-82, gр5@сliniса.ррtus.гu, http://www.pptus.ru/~w_clinica).

S u m m a r y : Peculiarities in development of arterial hypertension in liquidators of the Chernobyl nuclear power plant accident consequences were examined (70 persons of the main group and 99 persons of control group) The group of the liquidators of the Chernobyl nuclear power plant accident consequences is more frequently subjected to risk factors for development of cardiovascular diseases and target organ affection and they tend to fail ill earlier.

K e y w o r d s : CNPP disaster liquidators, arterial hypertension, endothelial dysfunction, index of mass of myocardium of the left ventricle, risk factors for development of cardiovascular diseases, low-density lipoproteids, microalbuminuria, “Intima-media” complex.

I n f o r m a t i o n a b o u t t h e a u t h o r ( s ) :Amelina Olga Vladimirovna, postgraduate student of the Department of Hospital Therapy

with courses of family medicine, clinical pharmacology and clinical laboratory diagnostics of Saint-Petersburg State Medical Academy named after I.I. Mechnikov, home tel. (8-4832)-91-21-60 , mobile phone 8-910-237-19-73. e-mail:[email protected]

Sokolova Ludmila Andreevna, professor of the Department of Hospital Therapy with courses of family medicine, clinical pharmacology and clinical laboratory diagnostics of Saint-Petersburg State Medical Academy named after I.I. Mechnikov, work tel.: (8-812)-275-72-03, tel.8-812-230-67-60, (8-812)-545-37-77, mobile phone 8-921-762-20-64, e-mail:[email protected]

Dubovoy Ivan Ivanovich,, professor of the Department of the Ecology and Natural Resources Management at BSU named after I.G.Petrovsky, Bryansk, head doctor of Municipal Healthcare Facility “City polyclinic №5”, 241004, Bryansk, Moskovsky p.,99, work tel. (8-4832) 63-03-82, e-mail:g р 5@ с lini са . рр tus. г u , http://www.pptus.ru/~w_clinica

31_941 © T.P. Khramykh, 2008

UDC: 616.34:616.12-008.331.4:616-005.1Khramykh T.P. Intestinal insufficiency development in hemorrhagic hypotension //

Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р.118-122.

S u m m a r y . In the hemorrhagic hypotension increasing an activity cavity and stripped factions amylase is connected with ischemia in pancreaticoduodenal region, conditionning breach of the correlation of the processes cavity and stripped of the digestion. In iliac gut of these phenomena carried the unabiding nature and gradually were replaced compensatory and adaptive process, directed on maintenance of the processes parietal digestion. In bowels prevails the activation a ferment prooxidant system that conditions its damage and development to intestine insufficiency in the hemorrhagic hypotension.

K e y w o r d s : hemorrhagic hypotension, intestine insufficiency, amylase, prooxidant and antioxidant systems.

I n f o r m a t i o n a b o u t t h e a u t h o r : Khramykh Tatyana Petrovna, Candidate of Medical Sciences, Assistant-Professor of the

department of Pathologic Physiology with the Course of Clinical Pathologic Physiology. 644043,

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Omsk, Lenin str., 12. Omsk State Medical Academy, tel.: 8(3812) 230-378, home tel.: 8(3812) 230-077, mobile phone: 8-(909)-536-8558, E.mail: [email protected]

32_1015 © N.Ch. Olimov, 2008

UDC: 613.6:677Olimov N.H. Extracardial regulation of cardiac rhythm and changes of kinin blood system

as a possible factor of sudden death in patients with acute myocardial infarction // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 122-127.

Respublicanskiy clinisheskiy center cardiology of Tajikistan, 735360, Dushanbe, str., I. Somoni, д. 59'а', tel.: 8-10-992-372-35-53-10, fax.: 8-10-992-372-248652, E-mail: [email protected]

S u m m a r y : The assessment of degree of disorders of extracardic regulation of cardiac rhythm and changing of kinin system in 530 patients with acute infarct myocardium was conducted. It was found that changing of kallikrein kinin system of blood (quick and massive formation, and quick disappearance of them) in biochemic regulation could be factor – predictor of disorders of extracardiac regulation and development of sudden death.

K e y w o r d s : extracardic regulation, kinin system, acute infarct myocardium, sudden death

I n f o r m a t i o n a b o u t t h e a u t h o r :Olimov Nasim Chodgaevish, doctor of medicine, head of the Respulicanskiy clinisheskiy

center cardiology Tajikistan, work tel.: (8-10-992-372) 35-53-10, home tel.: (8-10-992-372) 33-55-05, mobile phone (8-10-992) 918-24-81-59, e-mail: [email protected]

33_1029 © Sukhanov D.S., Savateeva T.N., Kovalenko A.L., A.Yu. Petrov, Romantsov M.G., 2008

UDC: 616.36:616-094.4:577.121.7Sukhanov D.S., Savateeva T.N., Kovalenko A.L., Petrov A.Yu., Romantsov M.G.

Antioxidant remaxol activity on the model of drug-induced liver damage // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 127-132.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; www.mechnik.spb.ru

Federal State Institution for Science «Institute of Toxicology» of the Federal Medical-Biological Agency of Russia, 192019, St.-Petersburg, Bekhterev str., tel./fax: 8(812)365-06-80

Scientific-technological pharmaceutic firm “POLYSAN”, Russia, 191119, Saint-Petersburg, Ligovsky prospect, 112, tel.: 8(812)110-82-25,112-13-79, е-mail: [email protected], STPF “POLYSAN” www.polysan.ru

S u m m a r y . The article shows the remaxol influence on main links of cells antioxidant system in case of experimental liver damage by medicine. The injection of remaxol to animals with hepatotoxical damage increases the level of restored glutathione, saves concentration of SH- groups of proteins in liver tissues on the level of intact animals, which allows to achieve the saving of thioldisulfide status of hepatocytes. Remaxol helps to keep intact the energetic substrates of hepatocytes by saving activity of glucosae-6-phosphatedehydrogenase

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(wich increases restored NADPH и glutathione enzymes), preventing oxidative damage glutathionereductase and glutathione-S-transferase. The antioxidant effect have been noted also in the case of catalase and glutathoineperoxidase’s activity study, the concentration of whose, under remaxol influence, had increased above normal level, and also in the case of decreasing concentration of the end products of lipid peroxidation (malondialdehyde and dyene conjugates), which confirms its clinical use in the cases of medicine and toxic liver damages.

K e y w o r d s : the remaxol, antioxidant system, hepatotoxical damage increasesI n f o r m a t i o n a b o u t t h e a u t h o r : Sukhanov D.S., Candidate of Medical Sciences, senior consulting physician for scientific

and clinical work Co Ltd “POLYSAN”, e-mail: [email protected]

34_1012 © U.A. Muminov, 2008

UDC: 616.36-002.2-08:616.988Muminov U.A. Evaluation of hepa-merts in patients with chronic viral hepatitis B

depending on the results of polymerase chain reaction // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 132-135.

Research Institute of Epidemiology, Microbiology & Infection Diseases, 2, Reshetov str, Tashkent, 100133, Republic of Uzbekistan, tel. (998-71) 1433605, fax (998-71) 2756692, [email protected].

S u m m u r y . Efficiency of hepa-mertz was studied in 80 patients with chronic viral hepatitis B (CHVB). Control group included 20 healthy donors of analogous age and sex structure. It was established that immunocorrecting effect was more expressed in HBsAg-negative patients with CHVB. Production of IL-1 and IL-8 in patients with CHVB depends on presence/absence of HBsAg in patients blood.

K e y w o r d : viral hepatitis B, hepa-mertz, cytocins.I n f o r m a t i o n a b o u t t h e a u t h o r s : Muminov U.A., head of the department of a clinic, research institute of Epidemiology,

Microbiology and Infectious Diseases of Uzbekistan Republic, 100133, Uzbekistan Republic, Tashkent, Reshetova str. 2, tел. (998-71) 1433605, fax (998-71) 2756692, [email protected].

35_1024 © V.F Antyufiev, А.V. Balazovich, О.N. Saveliev, 2008

UDC: 616-003.9:615.451.2 Antyufiev V.F., Balazovich A.V., Saveliev O.N. Reamberin - basic solution for infusion

therapy in restorative medicine // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 135-139.

Regional specialized hospital for medical rehabilitation “Chudovskoe Ozero”, 620053, Russia, Ekaterinburg, settlement Chudovskoe Ozero, Mira str., 1, tel. (3432) 637026, fax (3432) 637890, E-mail: [email protected]

S u m m a r y . In the present study 644 infusions of Reamberin solution were administered to 102 patients at 468 years of age. Among them were 14 patients after coronary artery bypass graft surgery and myocardial infarction; 15 patients with acute coronary syndrome and exertional angina; 11 patients with coronary heart disease II-B associated with circulatory deficiency; 13 patients with cardiac rhythm disorders (atrial fibrillation, paroxismal

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supraventricular tachycardia, extrasystole); 18 patients with primary hypertension associated with circulatory deficiency; 2 patients with myocardiodystrophy (with pain reaction); 8 patients at follow-up care after brain infarction; 7 patients with neuropathy (cardiophyshoneurosis, vertebral artery syndrome, aftereffects of head injury, multiocular sclerosis); 14 patients with chronic pancreatitis, hepatitis, fatty hepatosis; 8 patients with toxic alcohol and discirculatory encephalopathy and polyneuropathy; 10 patients with other diseases, including lower limbs arteriosclerosis obliterans, chronic renal failure. As basic solution for infusion Reamberin was administered alone and in combination with ozonous 0.9% NaCl, laser low intensity irradiation of blood, and plasmapheresis. First attempts of Reamberin implementation in physiatrics practice have demonstrated that it is safe, highly effective and prospective for use as basic metabolic solution for infusion.

K e y w o r d s : Reamberin, basic infusion therapy, and physiatrics.

36_922 © S.I. Danilov, A.S. Edin, 2008

UDC: 616.954.14:613.99Danilov S.I., Edin A.S. Factors leading to telogen alopecia in women // Herald of the

Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 139-142.S u m m a r y . According to the results of interviewing of 510 women visiting beauty

salons signs of telogenic alopecia were discovered in 108 (21,2%) respondents. Questionnaire survey of 108 patients made it possible to find out a few factors which influence on increased loss of hair: long-continued menses, age, occurrence of gastro-intestinal diseases and colouring of hair. Their combination must be admitted as unfavorable one in respect of progression of telogenic alopecia.

K e y w o r d s : questionnaire survey, telogenic alopecia. I n f o r m a t i o n a b o u t t h e a u t h o r s : Danilov Sergey Ivanovich, doctor of medicine, Professor, head of the Department

of Dermatovenerology Mechnikov Saint-Petersburg State Medical Academy, Russia, St.-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-96-34; fax: 8-812-545-10-12; e-mail: [email protected]

37_1049 © M.V.Alexandrov, E.G.Klocheva, I.V.Chistova, L.U.Vinogradova, 2008

UDC: 616.831-02:616.379-008.64Alexandrov M.V., Klocheva E.G., Chistova I.V., Vinogradova L.Yu. Berlition and

Milgamma use in diabetic polyneuropathy // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 142-146.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y : The efficiency of Berlition and Mylgama was compared in 40 patients with polyneuropathies and diabetes mellitus of I and II types. Neurological status, electoneuromyografia (ENMG), heartrythm variability were investigated before and after

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treatment. In patients with minimal polyneuropatic disfunction and diabetes mellitus type I combined treatment with Berlition and Mylgama is effective. In patients with minimal polyneuropathic dysfunction and diabetes mellitus of type II isoleuted treatment with Mylgama is effective. In the cases of moderate or severer polyneuropathic dysfunctions and diabetes mellitus of type II the combined treatment with both drugs is effective.

K e y w o r d s : Berlition, Mylgama, diabetic polyneuropathy.I n f o r m a t i o n a b o u t t h e a u t h o r s :Alexandrov Mikhail Vladimirovich – candidate of medical science, head of the

Department of neurology, neurosurgery and medical genetics Saint-Petersburg State Medical Academy named after I.I.Mechnikov (SPSMA). work phone: (812)543-0126, mobile phone: (952) 361-4631.

Klocheva Elena Georgievna – doctor of medical science, professor at the Department of neurology, neurosurgery and medical genetics Saint-Petersburg State Medical Academy named after I.I.Mechnikov (SPSMA). work phone: (812)543-0073, mobile phone: (321) 658-1872.

Chistova Inga Victorovna –assistant at theDepartment of neurology, neurosurgery and medical genetics Saint-Petersburg State Medical Academy named after I.I.Mechnikov (SPSMA). work phone: (812)543-0073, mobile phone: (812) 945-5233.

Vinogradova Ludmila Urievna – candidate of medical science, assistant at the Department of neurology, neurosurgery and medical genetics Saint-Petersburg State Medical Academy named after I.I.Mechnikov (SPSMA). work phone: (812)543-0073, mobile phone: (911) 943-3434.

38_1031 © V.A. Gluschenko

UDC: 616-089.5-032.829-06Gluschenko V.A. Risk factors of complications development in spinal cord anesthesia,

their analysis and remote results // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 146-149.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y . We made a view of 2105 persons, who was performing spinal anesthesia in surgery of low extremities, urology, hynecology and abdominal surgery. The most often complication was arterial hypotension – 29,8 % of cases. Bradycardia meeting in 11% of cases. In 6,7% occurs headache postpunction dural. Paraesthesia occurs in 7% of patients.

Intraoperative nausea was in 19%, postoperative nausea in 16%, vomiting in 7%. In 2 cases (patients with IV rate ASA) during anesthesia occur acute cardiac failure with ventricular fibrillation and patients died.

K e y w o r d s : spinal anesthesia, complications.I n f o r m a t i o n a b o u t t h e a u t h o r :Gluschenko Vladimir Anatolievich - candidate of medical science, head of the

Department of anesthesiology, reanimatology and intensivity theraphya Saint-Petersburg State Medical Academy named after I.I.Mechnikov (SPSMA). work phone: (812) 543-03-80, E-mail: [email protected]; Adress: Russis, 195271, Saint-Petersburg, Bestuzhevskaya str., home. 18 - 2, phone: 8(812)544-18-30.

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39_1056 © A.L. Kovalenko, F.I. Ershov, T.N. Savateeva, M.G. Romantsov, A.Yu. Petrov, 2008

UDC: 615.27:616.36:616-092.4Kovalenko A.L., Ershov F.I, Savateeva T.N., Romantsov M.G., Petrov A.Yu. Metabolic

preparation influence on liver functional activity in experiment // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 149-153.

Scientific-Technological Pharmaceutical Firm “POLYSAN”, Russia, 191119, Saint-Petersburg, Ligovsky prospect, 112, tel.: 8(812)110-82-25,112-13-79, е-mail: [email protected], STPF “POLYSAN” www.polysan.ru

State Research Institute of Epidemiology and Microbiology named after N.F. Gamaleya of Russian Academy of Medical Sciences, Russia, 123098, Moskow, str. Gamaleya, 18, phone: 8-495-193-43-06

S u m m a r y . The article reviews the studies on hepatoprotective metabolic correctors on the model of experimental virus- and toxic-induced lesions of the liver. On the basis of reamberin substrate compositions (Cytoflavin and Remaxol) were developed, which showed antihypotoxic effect, antioxidant activity was revealed and cytoprotective action on the background of metabolic effect was established. On the basis of the studied mechanism of action of medical compounds the preparations are recommended for clinical trials at chronic liver virus disorders.

K e y w o r d s : liver, viral affection, cytoflavin, remaxol.I n f o r m a t i o n a b o u t t h e a u t h o r s : Kovalenko A.L. - Scientific-Technological Pharmaceutical Firm “POLYSAN”, Russia,

191119, Saint-Petersburg, Ligovsky prospect, 112, tel.: 8(812)110-82-25,112-13-79, е-mail: [email protected], STPF “POLYSAN” www.polysan.ru

Ershov, Academician of the Russian Academy of Medical Sciences, head of the department of Interferon - State Research Institute of Epidemiology and Microbiology named after N.F. Gamaleya of Russian Academy of Medical Sciences, Russia, 123098, Moskow, str. Gamaleya, 18, phone: 8-495-193-43-06

40_854 © V.M. Shmeleva, V.A. Kobilyanskaya, N.V. Aganezova, L.P. Papayan, 2008

UDC: 616.15:615.272.6Shmeleva V.M. 1, Kobilyanskaya V.A. 1, Aganezova N.V. 2, Papayan L.P. 1 Influence of

haemocystein on plasma sensitivity to the activated C protein / V.M. Shmeleva1, V.A. Kobilyanskaya1, N.V. Aganezova2, L.P. Papayan1 // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 153-156.

1 Federal State Institution «Russian Research Institute of Hematology and Transfusiology of the Federal Agency for Advanced Technology Medical Aid», 191024, St.-Petersburg, 2 Sovetskaya str., 16, tel.: 8-812-274-56-50, fax: 8-812-717-25-50, 8-812-274-92-27, E-mail: [email protected] или [email protected]

2State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and

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Social Development of the Russian Federation», 191015, Kirochnaya str., 41, tel.: 272-52-06, fax: 273-00-39, e-mail: [email protected]

S u m m a r y : Homocysteine levels and APC resistance were studied in 28 patients with premenstrual syndrome and 30 controls. Our data indicate that increased homocysteine levels are associated with reduced anticoagulant response to activated protein C, which may contribute to prothrombotic effect of hyperhomocysteinemia.

K e y w o r d s : homocysteine, plasma sensitivity, activated protein C.

41_899 © D.V. Solomonov, N.N. Bogdanov, S.D. Shoferova, A.K. Makarov, K.P. Gamauno, 2008

UDC: 616.12-008.331.1:612.825.59:615.832Solomonov D.V.1, Bogdanov N.N.1, Shoferova S.D.2, Makarov A.K.1, Gamaunov K.P.1

Thresholds of cold sensitivity of articular reflex zones in estimation vegetative status of patients with hypertonic disease // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 156-159.

1State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», 191015, Kirochnaya str., 41, tel.: 272-52-06, fax: 273-00-39, e-mail: [email protected]

2State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y . It is shown estimated vegetative state hypertensive disease. It is shown interrelation sensitivity of some acupuncture auricular points and arterial pressure. There is shown possibility estimation the neural regulation arterial pressure by means sensitivity acupuncture auricular points. Krioreflexotest auricular used by estimated vegetative state.

K e y w o r d s : arterial hypertension, vegetative neural system, neural regulation arterial pressure, hypertensive disease, krireflexotest auricular.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Solomonov Dmitry Victorovich, assistant of the department of Reflexotherapy of

SPMAPDT. Tel.: 8-911-279-22-98Bogdanov Nikoly Nikolaevich, Doctor of Medicine, Professor, head of the Department of

Reflexotherapy of SPMAPDT. Tel.: 908-63-14Shofeorova Svetlana Dmitrievna, Candidate of Medical Sciences, Assistant Professor of

the Department of Physiotherapy and Balneology with the course of Rehabilitation, Apparatus Cosmetology and Reflexotherapy of the Faculty of Advanced Professional Training of SPSMA named after I.I.Mechnikov. Tel.: 291-08-47

Makarov Amdrey Konstantinovich Candidate of Medical Sciences, Assistant Professor of the Department of Reflexotherapy of SPMAPDT. Tel.:8-921-588-65-50

Gamayunov Konstantin Pavlovich, Candidatye of Medical Sciences, Assistant Professor of the Department of Reflexotherapy SPMAPDT. Tel.: 8-905-212-10-92

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42_843 © A.B. Zborovsky, B.V. Zavodovsky, L.E. Sivordova, O.S. Dmitrenko, I.A. Zborovskaya, 2008

UDC: 616.71-002.28:615.27Zborovsky A.B., Zavodovsky B.V., Sivordova L.E., Dmitrenko O.S., Zborovskaya I.A.

Differentiat therapy by chondroprotectors depending on antibody genesis to cartilage chondroitin sulfate in osteochondrosis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 159-164.

State Institution «Research Institute of clinical and experimental reumatoiogy» of the Russian Academy of Medical Sciences, 400138, Volgograd, Zemlythki str., 76, tel.: 8(8442) 35-56-48, fax: 8(8442) 93-42-11.

State Educational Establishment of Higher Professional Training «Sankt-Petersburg state pediatric academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 400066, г. Volgograd, pl.. Pavschih Bortsov, 1, tel.: 8(844)233-99-32

S u m m a r y : Antibodies to chondroitine sulfate (anti-CS) level was lower in the group with good results of «Alflutop» therapy than in group with poor results. The efficacy of «Alflutop» therapy was better in the group with anti-CS level lower 0,53. The efficiency of glucosamine sulfate did not depend on anti-CS level. Thus chondroprotectors efficiency in osteoarthritis depend on initial anti-CS level.

K e y w o r d s : osteochondrosis, depending on antibody genesis to cartilage chondroitin sulfate, therapy by chondroprotectors

I n f o r m a t i o n a b o u t t h e a u t h o r :Zavodovsky Boris Valerievich - 400121, Volgograd, Nikola Otrada prospect, 22, apt. 67,

work tel.: 8442 352903, home tel.: 790811, mobile phone: 9033740639, fax: 934211, e-mail: [email protected]

43_934 © I.V. Merkushina, 2008

UDC: 616-008.6:615.27Merkushina I.V. Cerebral protector component in endotoxicosis management // Herald of

the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 164-167.State Educational Establishment for Higher Professional Training “Mordvinian State

University named after N.P.Ogarev”, Russia, Mordvinian Republic, 430000, Saransk, Bolshevistskaya str. 68, tel:

S u m m a r y . The effect of preparations with cerebral protective effect in complex intensive care of endointoxication was studied. Cytoflavin has marked lipid-regulating cerebral protective effect which is realized through the decreased intensity of lipid peroxide oxidation and depression of phospholipase activity of the cerebral tissue structures. Positive effect is manifested early and is one of the mechanisms of quick arrest of intoxication syndrome that also defines the necessity of including cerebral protective component in endointoxication therapy.

K e y w o r d s : an endointoxication, Cytoflavin, cerebral protective effect.

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EPIDEMIOLOGY, DIAGNOSTICS, CLINIC AND PREVENTION OF INFECTIOUS AND PARASITIC DISEASES

44_908 © E.A. Orishak, A.G. Boitsov, L.Ju. Nilova, 2008

UDC: 616.34Orishak E.A., Boitsov A.G., Nilova L.Ju. Antibiotics and phages resistance of

conditionally pathogenic microorganisms in intestinal disbacteriosis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 167-170.

State Educational Establishment for Higher Professional Training «Saint-Petersburg State Medical Academy named after I.I. Mechnikov of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, Pyskarevskiy pr., 47, tel./fax: 8-812-543-01-95, е-mail: [email protected]; [email protected]

S u m m a r y : The evaluation of frequency and significance in the process of conditionally pathogenic microorganisms (CPM) isolation in intestinal disbacteriosis of children and adults is analyzed. Antibiotics resistance of CPM in intestinal disbacteriosis is estimated. The susceptibility test application to the bacteriophages of different trademarks for the effective elimination of CPM in intestinal disbacteriosis is proved.

K e y w o r d s : disbacteriosis, bacteriophages.I n f o r m a t i o n a b o u t t h e a u t h o r s :Orishak Elena Alexandrovna – candidate of medical science, assistant-professor of the

Department of Microbiology, Virology and Immunology of the Saint-Petersburg State Medical Academy named after I.I. Mechnikov, work tel./fax: (8-812) 543-01-95, e-mail: [email protected]

Boitsov Alexey Gennadievich – Doctor of Medicine, head of the department of Microbiology, Virology and Immunology of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav, work tel.: (8-812) 543-01-95, e-mail: [email protected]

Nilova Ludmila Jurjievna – head of the laboratory of the Department of Microbiology, Virology and Immunology of the Saint-Petersburg State Medical Academy named after I.I. Mechnikov, work tel./fax: (8-812) 543-01-95, e-mail: [email protected]

45_984 © E.Yu. Еrеmina, S.I. Zvereva, O.I. Nikitina, 2008

UDC: 616-002.44:615.322:612.017.1Eremina E.Yu., Zvereva S.I., Nikitina O.I. Symbiotic biocomplex influence on immune

system state in ulcer disease // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 170-174.

State educational establishment for higher professional training «Mordvinian State University named after N.P.Ogarev», Russia, Saransk, Bolshevistskaya St., 68, Phone: 8(8342)476885, e-mail: [email protected]

S u m m a r y . The objective is to study the influence of the synbiotic bioplex Normoflorin D on the condition of the immunity within the duodenal ulcer patients during the eradication therapy. The immune state of the patients was investigated according to the indexes of the humoral and cell mediated immunity. The violations of the humoral and the cell mediated immunity were revealed withing the duodenal ulcer patients at the stage of intensifying. The therapy aggravated the violations.

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Using the symbiotic bioplex Normoflorin D after the eradication therapy promoted the decrease of the intensity of the symptoms of the secondary state of the immunodeficiency at the stage of the intensifying of the duodenal ulcer.

K e y w o r d s : duodenal ulcer, symbiotic bioplex, immunity, therapy.I n f o r m a t i o n a b o u t t h e a u t h o r s :Eremina Elena Yurievna, Doctor of Medicine, head of the Department of Propedeutics of

Internal Diseases of SEEHPT “Mordvinian State University named after N.P.Ogarev”. Russia, 430000, Saransk, Bolshevistskaya str., 68, 8(8342)476885.

Zvereva Svetlana Ivanovna, Candidate of Medical Sciences of the department of Propedeutics of Internal Diseases – SEEHPT “Mordvinian State University named after N.P.Ogarev”. Russia, 430000, Saransk, Bolshevistskaya str., 68, 8(8342)476885, e-mail: [email protected].

Nikitina Olga Ivanovna, physician-therapeutist of the Military-Medical Commission of the Commissariat of Mordvinian Republic. 430000, Saransk, Respublikanskaya str., 43.

46_999 © I.Р. Baranova, L.A. Musatova, O.N. Lesina, L.I. Krasnova, 2008

UDC: 616.36-002.1:615.27:613.83Baranova I.Р., Musatova L.A., Lesina O.N., Krasnova L.I. Immune correcting action of

cycloferon in acute hepatitis C in users of phychoactive sunstances: dependence of efficiency on the initial level of immunological disorders // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 174-178.

S u m m a r y : Тhe purpose of a study was the determination the immunocorrecting effectiveness of the inductor of endogenous interferon - tsikloferon depending on the initial level of immunological disturbances with the sharp hepatitis C in patients, who use psycho-active substances. Shown that against the background therapy tsikloferon in drug-dependent patients is observed a reliable increase in the level СD4+, a decrease in the level СD3+, СD8+ (with the high correlation), is reduced the sojourn time of patients in the hospital. In the complex therapy of the virus hepatitis C (sharp phase) of tsikloferon renders the reliable immunocorrecting action: with [SIN] of the I - are restored the levels СD4+ and СD8+ to the standard; with [SIN] OF THE II - it increases the levels of T-cells to [SIN] of the I; with [SGIS] of the I are reduced the levels СD3+ and СD8+ to the normal indices; with [SGIS] OF THE III occurs a decrease in the levels of T-cells to [SGIS] OF THE II. To the initially normal indices СD3+, СD4+, СD8+ of tsikloferon does not render the influence.

К e y w o r d s : sharp hepatitis C, tsikloferon, correlation, levels СD4+, СD8+, СD3+.

I n f o r m a t i o n a b o u t t h e a u t h o r s :Baranova Irina Рetrovna.– phone: 8-960-322-44-69Lesina O.N. - e-mail: [email protected] Ольга

47_1055 © I.V. Likiy, N.A. Semenyako, T.V. Sologub, 2008

UDC: 616.36-002.2:614.1(498.3)

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Likiy I.V., Semenyako N.A., SologubT.V. Degree of cytolitic syndrome manifestation in patients with chronic hepatitis C and the structure of morbidity of the disease // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 178-182.

State Educational Establishment for Higher Professional Training «Saint-Petersburg State Medical Academy named after I.I. Mechnikov of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, Pyskarevskiy pr., 47, tel./fax: 8-812-543-01-95, E-mail: [email protected]; [email protected]

S u m m a r y . The increase in the prevalence of hepatitis C in Chisinau in six years was 2,1 times and 2,6 times cirrhosis C. The pace of development of fibrotic changes in the liver when hepatitis C is directly dependent on the level of serum ALT. There were analyzed 1257 data of patients with chronic hepatitis C in Chisinau for the period of observation from 2 to 11 years. PNALT amounted to 64 (5,1%) patients, PEALT-877 (69,76%), FLUXALT-316 (25,14%). Low levels of ALT raising was detected in 890 (70,8%) patients, the average-305 (24,3%), high levels of-62 (4,9%). Accelerated development of fibrous changes in the liver may have 367 patients (29,2%), with average levels of ALT. Quick fibrous change is possible from 316 patients (25,14%) of average level of activity and PEALT. Maximum fibrous risk of rapid change is possible from 62 patients (4,9%) with high levels of ALT and PEALT.

K e y w o r d s : viral hepatitis C, fibrosis, risk factors.I n f o r m a t i o n a b o u t t h e a u t h o r s : Liky I.V. – department of Infectious Diseases. Tel.: +37367156165. E-mail:

[email protected] Sologub Tamara Vasilievna – Doctor of Medicine, Professor, head of the department of

Infectious Diseases of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav

Semenyako Nadezhda Alexandrovna – post-graduate student of the department of Infectious Diseases of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav

48_1011 © Zh.Zh. Zhanibekov, 2008

UDC: 616.36-002-08:616.988Zhanibekov Zh.Zh. Ketotifen curative efficiency in complex therapy of patients with

acute viral hepatitis B // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 182-166.

Research Institute of Epidemiology, Microbiology & Infection Diseases, 2, Reshetov str, Tashkent, 100133, Republic of Uzbekistan, tel. (998-71) 1433605, fax (998-71) 2756692, [email protected].

S u m m u r y . Treatment of patients with acute viral hepatitis with ketotifen significantly decrease duration of main clinical symptoms in comparison with control group. Use of ketotifen in the complex therapy eliminates or decreases manifestations of clinical allergic symptoms. Therapy with ketotifen considerably decreases parameters of allergic reactions of various types according Gell and Coombs. Ketotifen also considerably decreases level of serum IgE in patients with acute viral hepatitis B, indicating to decrease of allergic reactions of immediate type.

K e y w o r d : acute viral hepatitis B, ketotifen, allergic symptoms.I n f o r m a t i o n a b o u t t h e a u t h o r s : Zhanibekov Zh.Zh., chief physician of Infectious Hospital, Nukus, research institute of

Epidemiology, Microbiology and Infectious Diseases of the Ministry of Public Health of

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Uzbekistan, 100133, Uzbekistan Republic, Tashkent, Reshetova str., 2, tel. (998-71) 1433605, fax (998-71) 2756692, umid _ bek 53@ mail . ru

49_1016 © D.S. Sukhanov, A.K. Ivanov, M.G. Romantsov, T.V. Sologub, A.L. Kovalenko, 2008

UDC: 616.24-002.5:615.06Sukhanov D.S., Ivanov A.K., Romantsov M.G., Sologub T.V., Kovalenko A.L. Correction

of hepatotoxicity caused by antimicrobial therapy with succinate-containing solution in patients with respiratory organs tuberculosis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 186-193.

S u m m a r y . The article presents the assessment of hepatoprotective activity of succinatecontaining solution –«remaxol»on tuberculosis infected respiratory organs in the case of concluded specific antibacterial polychemotherapy. The therapy effectiveness is assessed by clinical display of medicinal hepatotoxicity, the activity of cytolytic ferments and markers of cholestatic syndrome in regards to types of adaptation reactions. The positive influence of «remaxol» on display of medicinal hepatotoxicity and adaptation reactions of an organism is shown, which points on active use of plastic substrates, testifying the increase of reparative processes in hepatocytis, benefiting the restoration of liver tissue structure and decrease of pathological types of reactivity at patients with respiratory organs tuberculosis.

K e y w o r d s : remaxol, hepatoprotective activity, patients with respiratory organs tuberculosis

I n f o r m a t i o n a b o u t t h e a u t h o r s : Sukhanov D.S., Candidate of Medical Sciences, senior consulting physician for scientific

and clinical work Co Ltd “POLYSAN”, e-mail: [email protected]

50_1054 © B.I. Otaraeva, Т.В. Sologub, N.A. Kivisepp, 2008

UDC: 616.981.42:616.36Otaraeva1 B.I., Sologub2 Т.В., Kivisepp2 N.A. . Liver damage in different forms of

brucellosis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 193-196.

1Infectious diseases, epidemiology, dermatovenereology and AIDS department State Educational Establishment «North-Ossetia State Medical Academy» of the Federal Agency for Public Health and Social Development, Russia, 362019, North Ossetiya-Alaniya Republic, Vladikavkaz, Pushkinskaya str., 40, tel: 8(8672) 53-42-21

2State Educational Establishment for Higher Professional Training «Saint-Petersburg State Medical Academy named after I.I. Mechnikov of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, Pyskarevskiy pr., 47, tel./fax: 8-812-543-01-95, E-mail: [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y . With the aim of improvement of the diagnostics and treatment of the diseases with hepatomegaly and jaundice 100 patients with different stages of Brucellosis were examined. Experiment on laboratory animals with the help of histological methods was performed to study the pathogenesis of the liver injury in the Brucellosis. It was estimated that liver is involved in the pathological process at all stages of Brucellosis (acute, subacute and

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chronic). Mezenchymal inflamation occurs most often, but in 9% of cases parenchymal hepatitis with jaundice can be revealed too.

K e y w o r d s : brucellosis, hepatitis, bleeding.I n f o r m a t i o n a b o u t t h e a u t h o r s : Otaraeva B.I. – department of Infectious Diseases, Epidemiology, Dermatovenerology

and AIDS of SEEHPT «North-Ossetia State Medical Academy» of the Federal Agency for Public Health and Social Development, Russia, 362019, North Ossetiya-Alaniya Republic, Vladikavkaz, Pushkinskaya str., 40, tel.: 8(8672) 53-42-21

Sologub Tamara Vasilievna – Doctor of Medicine, Professor, head of the department of Infectious Diseases of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav

Kivisepp N.A - department of Infectious Diseases of the Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav, Russia, phone / fax: 8-812-717-27-07

51_990 © A.V. Gordeets, V.A. Ternovoi, A.A. Chernikova, 2008

UDC: 616.981.717(571.63)Gordeets A.V., Ternovoy V.A., Chernikova A.A. Clinical picture of borreliosis caused by

ticks and its comparison with the results of borrelia in Premorye Territory // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 196-200.

State Educational Establishment for Higher Professional Training «Vladivostok State Medical University» of the Federal Agency for Public Health and Social Development of the Russian Federation, Russia, 690014, Vladivostok, pr. Ostryakova, 2. Tel. 8 (4232) 45-17-06. е-mail: [email protected]

Federal Service for Surveillance in Cosumer Right Protection and Human Well-being, SRC VB Vector, Koltsovo 630559, Russia; tel. 8 (383) 336-64-38, е-mail [email protected]

S u m m a r y . The clinic tick-born borrelliosis was investigated in children in Primorsky region and its comparison to genotypes Borrelia, allocated at patients from whey of blood was spent. The clinic borrelial infection it was characterized by occurrence rash, a fever, regional lymphnoditis, attributes of defeat of cardiovascular system, and also high frequency (up to 51,85 %) no rash forms of illness. The most frequently detected genospecies was B. garinii, but for clinic of this disease was not characteristic defeats central nervous system, as in other regions of Russia.

K e y w o r d s : The tick-born borrelliosis, DNA isolation to genotypes, children.I n f o r m a t i o n a b o u t t h e a u t h o r s : Gordeets Alvina Vasilievna, Doctor of Medicine, Professor, head of the course of

Children Infectious Diseases of Pediatric Department N1 – SEEHPT «Vladivostok State Medical University of the Federal Agency for Public Health and Social Development» 690014. Russia 690950, Vladivostok, Ostryakova prospect,2, tel.: 8(4232) 229-789.

Ternovoy Vladimir Alexandrovich, Candidate of Biological Sciences, head of the sector of Molecular Diagnostics of FGUN GNT VB «Vector» of Rospotrebnadzor, 630559, Novosibirsk region, Koltsova 32-8, tel.: 8(383) 336-438

Chernikova Anastasiya Anatolievna, assistant – SEEHPT «Vladivostok State Medical University of the Federal Agency for Public Health and Social Development», 690014. Russia, 690950, Vladivostok, Ostryakova prospect, 2, mobile phone: 8-9241-30-43-57; e-mail: [email protected]

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52_981 © A.A. Goliusov, J.V. Martynov

UDC: 614.23:616.314:578.542 Goliusov A.A., Martynov Yu.V. Occupational risk evaluation of HIV-infection in

dentists // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 200-204.

State Educational Establishment for Higher Professional Training « Moscow State University of Medicine and Dentistry of the Federal Agency for Public Health and Social Development of the Russian Federation», Russia, 127473, Moscow, street Delegatsky d.20/1. т. 8(495)973-32-61, 8(495)681-65-13.

S u m m a r y : The analysis of 241 questionnaires selected during sociological research allowed to estimate the level of knowledge on HIV/AIDS problem. It was revealed the presence of incorrect stereotypes and incorrect knowledge of occupational risk factors of HIV transmission among dentist;

As a result of questioning was absence of proof algorithm of behavior in the conditions of an emergency during occupation. Only 1/3 respondents – dentists and nurses have specified correctly the sequence of actions after exposure.

K e y w o r d s : dentistry, HIV, exposure, occupational risk.I n f o r m a t i o n a b o u t t h e a u t h o r s : Goliusov Alexander Alexandrovich, Candidate of Medical Sciences, assistant of the

department of Infectious Diseases and Epidemiology of SEEHPT “Moscow State Medical-Stomatological University of Roszdrav”, 127473, Moscow, Delegatskaya str., 20/1. tel. (495) 973-32-61, 681-65-13

Martynov Yuriy Vasilievich, Doctor of Medicine, Professor of the department of Infectious Diseases and Epidemiology of SEEHPT “Moscow State Medical-Stomatological University of Roszdrav”, 127473, Moscow, Delegatskaya str., 20/1. tel. (495) 973-32-61, 681-65-13

53_994 © M.A. Melovtsova, 2008

UDC: 616.36.-002.2-018:616-076Melovtsova M.A. Laboratory and morfological peculiarities of chronic virose hepatitis

В // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. – № 4(29). – Р. 204-208.

State Educational Establishment of High Professional Education “Saint-Petersburg State Medical Academy of Federal Agency of Care of Public Health and Social Development”, 195067, Saint-Petersburg, Piskarevsky pr., 47; telefone 8-812-543-96-09, fax: 8-812-740-15-24, E-mail: [email protected]; [email protected]

S u m m a r y : The Patients with HBV genetic material in the liver tissue characterize by mild severity of clinical and biochemical indices in the base of high sinusoidal liver cells activation due to histological activity of pathological process.

K e y w o r d s : hepatitis B, polymerize chain reaction, Kupffer cells.I n f o r m a t i o n a b o u t t h e a u t h o r ( s ) :Melovtsova Marina Albertovna - postgraduate student of the Department of Internal

Diseases with Therapeutical and Nefrological Course of Saint-Petersburg State Medical Academy named after I.I. Mechnikov , work tel.: (8-812) 543-05-86, home tel.: (8-812)226-24-78, e-mail: [email protected]

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MEDICAL PSYCHOLOGY

54_1043 © Yu.A Pavlova, M.G. Romantsov,2008

UDC: 616.89:612.833-052.63:37Pavlova Yu.A, Romantsov M.G. Psycological-pedagogical conditions for the development

of skills of information activity of students // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р.

State Educational Establishment for Higher Professional Training «Saratov State University named after N.G.Chernyshevsky of the Federal Agency for Public Health and Social Development» Russia, 410012, Saratov, Astrahanskaya street, 83, tel./ fax 8(845-2)27-85-29

State Educational Establishment for Higher Professional Training «Saint-Petersburg State Medical Academy named after I.I. Mechnikov of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, Pyskarevskiy pr., 47, tel./fax: 8-812-543-01-95, E-mail: [email protected]; [email protected]

S u m m a r y . This article is devoted to the problem of the formation of skills of informational students activity and psychology – pedagogical conditions. The characteristics of this psychology – pedagogical conditions, the importance of their use in the condition of the qualitative updating reforming of higher education are given.

K e y w o r d s : informational activity, the formation of skills of informational activity, psychology – pedagogical conditions.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Pavlova Yulia Anatolievna - Post graduate student Saratov State University, Russia,

Saratov, 410012, Astrahanskaya street, 83, tel./ fax: +7(845)2-27852, e-mail: [email protected]

Romantsov Mikhail Grigorievich – Doctor of Medicine, Professor of the department of Infectious Diseases of SEEHPT Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav”

55_845 © F.I. Soloviev, A.N. Zharkov, I.V. Kharitonova, S.L. Solovieva, V.I. Nikolaev, 2008

UDC: 616.89:616.12-008.3Soloviev F.I., Zharkov A.N., Kharitonova I.V., Solovieva S.L., Nikolaev V.I. Miocardial

electric activity of people with different psychological properties of a person during emotional stress // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 208-211.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: : mechnik @ gmail . com ; [email protected]; www.mechnik.spb.ru

S u m m a r y : Psychological properties of the person (extraversion/introversion and emotional stability/lability) are determined at 132 healthy volunteers of 19-32 years on model of acute emotional stress (an examination situation).

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During emotional stress changes of intervals of an electrocardiogram are analyzed in comparison with a condition of functional rest. It is revealed, that different combinations of psychological properties influence on change of conductivity in a myocardium, determine intensity of responses of heart.

K e y w o r d s : psychological properties, emotional stress, m iocardial electric activity.

56_855 © N.V. Lokhmatkina, I.M. Nikolskaya, O.Yu. Kuznetsova, 2008

UDC: 616.89:618.17-009Lokhmatkina N.V., Nikolskaya I.M., Kuznetsova O. Yu. Control behaviour of patients of

the general medical practice exposed to violence from their intimate partner. // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 211-215.

State Educational Establishment for Additional Professional Training «Saint-Petersburg Medical Academy for Post-Diploma Training of the Federal Agency for Public Health and Social Development of the Russian Federation», 191015, Kirochnaya str., 41, tel.: 272-52-06, fax: 273-00-39, e-mail: [email protected]

S u m m a r y . This study compared the coping of 80 abused and 137 non-abused women who had been attending 24 random general practice clinics in St Petersburg. Abused patients had a higher level of task oriented and emotion oriented coping, while having avoided social support. These patients more frequently accepted responsibility and used the escape-avoidance strategy. Their high level of emotion oriented coping correlated with a high level of depression. The data suggests that abused patients have to be referred to psychologists, psychotherapists, and social workers.

K e y w o r d s : интимные партнеры, насилие, депрессивность, проблемно-ориентированный и эмоционально-ориентированный копинг.

SCIENTIFIC REVIEWS

57_1003 © M.G. Romantsov, L.G. Goryacheva, D.S. Sukhanov, T.V. Sologub, A.Yu. Petrov, A.K. Ivanov, O.V. Anikina, 2008

UDC: 616.36-002-08:615.015.35Romantsov M.G., Goryacheva L.G., Sukhanov D.S., Sologub T.V., Petrov A.Yu., Ivanov

A.K., Anikina O.V. Correction of drug-induced liver damages by succinate-containing medicines // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 215-220.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: [email protected]; [email protected]; www.mechnik.spb.ru

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S u m m a r y . The article deals with literary data on undesirable reactions to medicinal therapy (antibiotics, protozoa preparations, antiviral agents). Drug-induced lever disorders (hepatotoxicity, cholestasis) are shown to be more frequent.

The most common hepatotoxicity occurring in case of antimicrobial polychemotherapy is described in patients with tuberculosis. The mechanism of hepatotoxicity development and pathogenesis of drug-induced liver lesions is presented and treatment principles are characterized. New classification of succinate-containing medical products and new original succinate-containing preparations is presented, the mechanism of their action is characterized, their indications are proved at drug-induced liver disorders.

K e y w o r d s : drug-induced lever disorders, succinate-containing medical products, сorrection

I n f o r m a t i o n a b o u t t h e a u t h o r : Romantsov Mikhail Grigorievich, Doctor of Medicine, Professor of the department of

Infectious Diseases of SEEHPT Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav, deputy-director of STPF “POLYSAN”, тел.:  ,

58_1023 © A.F. Semyanovich, Yu.G. Shanko, 2008

UDC: 616.8-089:615.451.2Semyanovich A.F., Shanko Yu.G. Pathogenic appropriateness of substrate solutions with

antihypoxic activity use in acute and early postoperative periods in neurosurgical patients // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 220-224.

State institution “Research Institute of Neurology, Neurosurgery and Physiotherapy” of the Ministry of Public Health of Belarus Republic

S u m m a r y . In article the data of the review of the literature on a problem pathogenesis of acute local brain disorders are analyzed. Biochemical and pathogenic expediency of the use drug of amber aside as neurotherapy was shown. In article the data of the effectiveness in the acute period of local brain disorders (20 patients with brain injury II and III type; 10 patients with remove of supratentorial and 10 patients with remove of subtentorial brains tumors) are analyzed.

The addition of the Reamberinum in the treatment was lead to normalization of intracranial pression and improve of neurological status of the patients.

K e y w o a r d s : acute local brain disorders, drug of amber aside – Reamberinum, the effectiveness

EXPERIENCE EXCHANGE

59_888 © Д.Г. Берест, А.Г. Шиман, Е.И. Ткаченко, 2008© D.G. Berest, A.G. Shiman, E.I. Tkachenko, 2008

UDC: 616.33-009:616-001.22:611.714Berest D.G., Shiman A.G., Tkachenko E.I. Use of transcranial electrical stimulation in

therapy of gastro-esophageal relux disease // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 224-226.

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State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: : mechnik @ gmail . com ; [email protected]; www.mechnik.spb.ru

S u m m a r y : The results of treatment of 55 patients with gastroduodenal reflux disease. Our new application of transcranial electrostimulation revealed high effectiveness in the treatment of patients with gastroduodenal reflux disease.

K e y w o r d s : рhysiotherapeutic methods, gastroduodenal reflux disease.I n f o r m a t i o n a b o u t t h e a u t h o r s : Shiman Alfred Georgievich, Doctor of Medicine, Professor, head of the department of

Physiotherapy and Balneology with the course of Rehabilitation, Apparatus Cosmetology and Reflexotherapy of the Faculty for Advanced Professional Training of SPSMA named after I.I.Mechnikov, tel: 291–08–47

Berest Dmitry Grigorievich, head of Endoscopic department of the hospital named after Peter the Great

Tkachenko Evgeny Ivanovich, Doctor of Medicine, Professor, Chief Gastroenterologist of the Committee for Public Health of the Saint-Petersburg Government, head of the department of Propedeutics

60_912 © G.I. Sinenchenko, O.A. Kozlov, S.I. Peregudov, A.E. Demko, M.G. Zaytcev.

UDC: 616.381-002:[616.334+616.342]616-002.44:615.281Sinenchenko G.I., Kozlov O.A., Peregudov S.I., Demko A.E., Zaitsev M.G. Endolymphatic

antibiotic therapy use for the treatment of general peritonitis in case of perforation of pyloroduodenal ulcers // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 226-228.

Kirov Military Medical Academy, the Russian 194044, Saint-Petersburg, Lebedeva str. 6, tel.: 8-812-329-71-02.

S u m m a r y : Endolymphatic administration of the antibiotics solution as a part of a complex treatment in patients with pyloroduodenal ulcers complicated by perforation and acute diffuse peritonitis has allowed to improve the results of treatment this pathology and associated with lower frequency of postoperative complications up to 18,2 %.

K e y w o r d s : acute diffuse peritonitis, еndolymphatic administration of the antibiotics solution.

61_923 © S.V. Klyuchareva, S.I. Danilov, E.A. Mamontova, A.A. Dubrovina, N.B. Melnikova, 2008

UDC: 616.5-005-08Klyuchareva S.V., Danilov S.I., Mamontova E.A., Dubrovina A.A., Melnikova N.B.

Modern methods of treatment of skin vascular pathology // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 228-232.

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State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: mechnik @ gmail . com ; [email protected]; www.mechnik.spb.ru

S u m m a r y : The results of treatment with the method of selective laser destruction of vascular skin defects are presented. The treatment of vascular pathologies was made on yellow wave length 578 nm. In the range of 0,8-1,7 Vt. of average power and the time of exposition from 0,1 till 0,3 sec., which depended on the kind and localisation of the defect. The positive results of the treatment of vascular skin neoplasms, which were received, vividly show the advantages of laser apparatus on copper stefms “Yahroma-med” for treatment of such pathologies as telangiectasias, hemangioma, difficult studies of rosacea.

K e y w o r d s : skin vascular pathology, methods of treatment, use of «vascular» lasers.

I n f o r m a t i o n a b o u t t h e a u t h o r s :Klyucharyeva Svetlana Victorovna, doctor of medicine – Mechnikov Saint-Petersburg

State Medical Academy, Department of Dermatovenerology, Russia, St.-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-96-34; fax: 8-812-545-10-12; e-mail: [email protected]

Danilov Sergey Ivanovich, doctor of medicine – Mechnikov Saint-Petersburg State Medical Academy, Department of Dermatovenerology, Russia, St.-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-96-34; fax: 8-812-545-10-12; e-mail: [email protected]

Mamontova Elena Alexandrovna, full-time post-graduate student – Mechnikov Saint-Petersburg State Medical Academy, Department of Dermatovenerology, Russia, St.-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-96-34; fax: 8-812-545-10-12; e-mail: [email protected]

Dubrovina Anna Alexandrovna, full-time post-graduate student – Mechnikov Saint-Petersburg State Medical Academy, Department of Dermatovenerology, Russia, St.-Petersburg, Piskarevsky prospect, 47, tel.: 8-812-543-96-34; fax: 8-812-545-10-12; e-mail: [email protected]

Melnikova Nataliya Borisovna, Saloon «Lanezh», Russia, Vologda

62_920 © I.E.Esaulenko, A.V.Nikitin, O.L.Shatalova, 2008

UDC: 616. 248+616. 216:615.849.19 Esaulenko I.E., Nikitin A.V., Shatalova O.L. Efficiency of laser puncture of chronic

sinusitis of patients with bronchial asthma // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 232-235.

State Educational Establishment for additional Professional «Voronezh N.N. Burdenko State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 394036, Studencheakaja str., 10, tel.: 52-54-89, 52-02-51, fax: (4732)53-00-05, Е-mail: [email protected]

S u m m a r y : The effectiveness of treatment of chronic rhinosinusitis at patients with asthma bronchial middle gravity on applieded the laserpuncture by influence at points biological by laser infrared spectre. The effectiveness clinical of treatment displayed by dynamic positive of clinical instrumental and spirometric data chez asthma bronchial and the rhinosinusitis that are confirm by rhoentgenologic investigations.

K e y w o r d s : asthma bronchial mixed, laserpuncture, biological active points, laser ionizing low intensity.

I n f o r m a t i o n a b o u t t h e a u t h o r s :

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Esaulenko Igor Eduardovitch, rector of medical academy, name N.N.Burdenko,doctors degeee,professor, telephone 59-89-90

Nikitin Anatoly Vladimirovich, head of the faculty propedevtics of internal of medicine, doctors degree, professor, telephone 36-68-31

Shatalova Olga Leonidovna, assistant of the faculty propedevtics of internal of medicine, candidate of medical sciences. Telephone 53-11-56; Fax 53-00-05; [email protected]; 8-951-567-53-02.

63_911 © R.F. Galeev, S.D. Shoferova, E.N. Andrievscaya, 2008

UDC: 616.211-002:616-056.3:615.844.6Galeyev R.F, Shofeorova S.D., Andrievsky E.N. Endonasal ipratropium bromide

electrophoresis use in treament of patients with allergic rhinitis // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 235-238.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: : mechnik @ gmail . com ; [email protected]; www.mechnik.spb.ru

S u m m a r y : Treatment of 50 patients with allergic rhinitis is lead. New method of medical electrophoresis by ipratropium bromidi developed by us was used. Its high efficiency in treatment of patients with allergic rhinitis was proved.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Galeev Radik Faritovich, head of the Clinic of Otorhinolaryngology of Mechnikov Saint-

Petersburg State Medical Academy, tel.: 543-94-13.Shofyerova Svetlana Dmitrievna, candidate of medical sciences, assistant-professor of the

Department of Physiotherapy and Balneology with the Course of Rehabilitation, Apparatus Cosmetology and Reflexology of the Faculty of Advanced Training of Mechnikov Saint-Petersburg State Medical Academy, tel.: 291–08–47.

Andrievskaya Elena Nikolaevna: doctor of the Clinic of Otorhinolaryngology of Mechnikov Saint-Petersburg State Medical Academy. tel.543-94-13.

PERSONNEL TRAINING

64_891 © Е.I. Akimova, A.M. Bolshakov, V.I. Dontsov, O.V. Zakharyatcheva, V.N. Krutko, O.A. Mamikonova, N.S. Potyomkina, T.M. Smirnova, 2008

UDC: 613.8:681.3

Akimova E.I.1, Bolshakov A.M.1, Dontsov V.I.2, 3, Zakharyatcheva O.V.2, Krutko V.N.1, 2, Mamikonova O.A.2, Potyomkina N.S.2, Smirnova T.M.2 Complex of computer systems for hygienic education of the population: I. The problem characteristic,

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principles of development and general description of the complex // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 238-245.

1State Educational Establishment for Higher Professional Training «Moscow Medical Academy named after I.M.Sechenov of the Federal Agency for Public Health and Social Development», Russia. 119881, Moscow, B.Pirogovskaya str., 2/6, tel.: 8-495-248-05-53.

2Institute of Systemic Analysis of the Russian Academy of Sciences, Russia, 117312, Moscow, 60-th October Anniversary prospect, 9, tel.: (499)135-24-38, fax (499)783-91-32.

3State Educational Establishment for Higher Professional Training “Moscow Medical-Stomatological University of the Federal Agency for Public Health and Social Development”, 103473, Moscow, Delegatskaya str., 20/1, tel.: 8(495)973-32-61, 8(495)681-65-13, 8(495)971-25-44.

S u m m a r y : The problem of demographic crisis in Russia characterized by the low birth rate, high population death rate, depopulation, deformation of the demographic pyramid (the sharp increase of the elderly in the society) results in the growth of the coefficient of the demographic loading. The said makes actual the tasks of the mass population recovery and the intensive introduction of the technologies of a human valuable able-bodied life period increase as never before. The given tasks are accomplished in the network of programs on the hygienic educating of the population actively developed in the medical universities.

The modern computer technologies have the potential of the substantial rise of the efficiency of the public recovery arrangements that permits to use actively the latest achievements of the science and practice of the hygiene at the popular level (for home and family).

In the work involved the results of the authors in the sphere of the development of the computer systems for health and longevity of the popular level are presented. The aim of the work was to create the tools that could permit a man with no medical education to utilize the to-date professional knowledge and the achievements of the hygienic science in the field of the active forming of health for solving one’s private tasks for recovery.

K e y w o r d s : computer systems, population, hygienic education, active health maintenance.

I n f o r m a t i o n a b o u t t h e a u t h o r s : Krutko Vyacheslav Nikolaevich – mobile phone: 8-916-1925242, work tel.: 8-499-

1357901; home tel.: 8-495-1564511, [email protected]

HISTORY OF MEDICINE

65_826 © Yu.A. Tsimokha., A.A. Klimov, A.N. Nikanov, O.I. Tabarcha, 2008

UDC: 613.62:362.654:347.764Tsimokha Yu.A., Klimov A.A., Nikanov A.N., Tabarcha O.I. Aspects of development of

social insurance from accidents at work and occupational diseases in Russia // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 245-248.

Research Laboratory, Federal State Institution for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor of the Russian Federation», Murmansk region, 184250, Murmansk region, Kirovsk, Lenin prospect, 34, tel.:(815-31) 91144, fax: (815-31) 91174, e-mail: [email protected]

S u m m a r y . Development of obligatory social insurance from accidents on manufacture and occupational diseases is closely associated with the development of the general system of social insurance in Russia.

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Now in connection with introduction into practice of the Federal law № 125-FZ from July, 24th, 1998 on obligatory social insurance from accidents in industry and occupational diseases, single payments, monthly payments, temporary invalidity and rehabilitation, including medical aid in primary treatment of victims of serious accidents in industry are carried out.

But it is only the first, difficult and intense stage of realization of a new kind of social insurance. Further steps should be referred on its optimization. At the same time not only previous historical experience should be taken into consideration, but also the experience of realization of the Federal law № 125-FZ and regional aspects of realization of obligatory social insurance from accidents in industry and occupational diseases.

K e y w o r d s : s o c i a l i n s u r a n c e : accidents in industry, occupational diseases.

I n f o r m a t i o n a b o u t a u t h o r s :Nikanov Alexander Nikolaevich, Research Laboratory, Branch of the Federal State

Institution for Science «Northwest Scientific Center for Hygiene and Public Health of Rospotrebnadzor of the Russian Federation», 184250, Murmansk region, Kirovsk, Lenin prospect, 34, tel.:(815-31) 91144, fax: (815-31) 91174, e-mail: [email protected]

SHORT COMMUNICATIONS

66_844 © V.А. Voronov, A.N. Pashchinin, S.V. Levin, 2008

UDC: 616.282;616.831.77-07Voronov V.А., Pashchinin A.N., Levin S.V. Result of otoneurological examination of

patients with Kiari I anomaly // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2008. - № 4(29). – Р. 248-252.

State Educational Establishment of Higher Professional Training «Mechnikov Saint-Petersburg State Medical Academy of the Federal Agency for Public Health and Social Development of the Russian Federation», 195067, St.-Petersburg, К-67, Piskarevsky prospect, 47, tel. (812)543-96-09, fax: (812)140-15-24, e-mail: : [email protected]; [email protected]; www.mechnik.spb.ru

S u m m a r y : Malformation Kiary 1 is complicated problem. Patients could come not only to neurologist but to ENT-doctor to. We sound remember about this patients and otoneurological that they have. At traditional otorhinolaryngological examination using additional X-ray examination methods patients with АК showed: azygomorphous lesion of hearing function; vestibular dysfunction both peripheral, and, mainly, central level; irritation of trunk vestibular formations, including elements of mesencephalon lesion; slight cerebellar symptoms and quite often insignificant craniocerebral nerve function disorders at the level of posterior cranial fossa; disturbance of optokynetic horizontal and sometimes vertical nystagmus thus showing the involvement of the back longitudinal bundle of the brain stem into the process.

K e y w o r d s : аномалия Киари 1, слуховая и вестибулярная функции.I n f o r m a t i o n a b o u t t h e a u t h o r s : Pashinin Alexander Nikolaevich – Candidate of Medical Sciences, Assistant-Professor,

head of the department of Otorhinolaryngology of SEEHPT “Saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav, Russia, 195067, Saint-Petersburg, Piskarevsky prospect, 47, SPSMA named after I.I.Mechnikov, tel.: 8(812) 543-94-13.

Voronov Victor Alexeevich – Candidate of Medical Sciences, assistant of the department of Otorhinolaryngology of SEEHPT “Saint-Petersburg State Medical Academy named after I.I.Mechnikov”, Russia, 195067, Saint-Petersburg, Piskarevsky prospect, 47, SPSMA named after I.I.Mechnikov, work tel.: 8(812) 543-94-13, mobile phone: 8-911-216-06-28

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Levin S.V. – post-graduate student of the department of Otorhinolaryngology of SEEHPT “saint-Petersburg State Medical Academy named after I.I.Mechnikov of Roszdrav”, Russia, 195067, Saint-Petersburg, Piskarevsky prospect, 47.

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