08/03/2020 Kit Components Product code Description

Kit Components08/03/2020

Product code Description

1610449 Silver Stain Plus™ Kit1610449EDU

Components:1610448 Development Accelerator Reagent1610461 Fixative Enhancer Concentrate1610462 Silver Complex Solution1610463 Reduction Moderator Solution1610464 Image Development Reagent

Page 1/8Safety Data Sheet

acc. to OSHA HCSPrinting date 08/03/2020 Reviewed on 06/25/2020

51.1.5

1 Identification· Product identifier· Trade name: Development Accelerator Reagent· Catalog or product number: 1610448, 1610448EDU· CAS Number:497-19-8

· EC number:207-838-8

· Index number:011-005-00-2

· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:Bio-Rad Laboratories, Life Science Group2000 Alfred Nobel DriveHercules, California 94547 (510)741-1000

· Information department: [email protected]· Emergency telephone number:1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION orACCIDENT.510-741-1000

* 2 Hazard(s) identification· Classification of the substance or mixtureEye Irrit. 2A H319 Causes serious eye irritation.

· Label elements· GHS label elements The substance is classified and labeled according to the Globally Harmonized System (GHS).· Hazard pictograms

GHS07

· Signal word Warning· Hazard statementsH319 Causes serious eye irritation.

· Precautionary statementsP264 Wash thoroughly after handling.P280 Wear eye protection / face protection.P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to

do. Continue rinsing.P337+P313 If eye irritation persists: Get medical advice/attention.

· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.

(Contd. on page 2) US



Trade name: Development Accelerator Reagent

(Contd. of page 1)

51.1.5

· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Substances· CAS No. Description:497-19-8 sodium carbonate

· Identification number(s):· EC number: 207-838-8· Index number: 011-005-00-2· Additional information: For the wording of the listed risk phrases refer to section 15.

* 4 First-aid measures· Description of first aid measures· General information No special measures required.· After inhalation Supply fresh air; consult doctor in case of complaints.· After skin contact Generally the product does not irritate the skin.· After eye contact Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.· After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.

* 5 Fire-fighting measures· Extinguishing media· Suitable extinguishing agents Use fire fighting measures that suit the environment.· Special hazards arising from the substance or mixture No further relevant information available.· Advice for firefighters· Protective equipment: Wear self-contained respiratory protective device.

* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions: Do not allow to enter sewers/ surface or ground water.· Methods and material for containment and cleaning up: Pick up mechanically.· Reference to other sectionsSee Section 7 for information on safe handlingSee Section 8 for information on personal protection equipment.See Section 13 for disposal information.

· Protective Action Criteria for Chemicals· PAC-1:

7.6 mg/m³(Contd. on page 3)

US




(Contd. of page 2)

51.1.5

· PAC-2:83 mg/m³

· PAC-3:500 mg/m³

* 7 Handling and storage· Handling· Precautions for safe handling No special measures required.· Information about protection against explosions and fires: No special measures required.

· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: Keep receptacle tightly sealed.· Specific end use(s) No further relevant information available.

* 8 Exposure controls/personal protection· Additional information about design of technical systems: No further data; see item 7.

· Control parameters· Components with limit values that require monitoring at the workplace: Not required.· Additional information: The lists that were valid during the creation were used as basis.

· Exposure controls· Personal protective equipment· General protective and hygienic measuresKeep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.Avoid contact with the eyes.Avoid contact with the eyes and skin.

· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

· Eye protection:Safety glassesTightly sealed goggles.

US

(Contd. on page 4)




(Contd. of page 3)

51.1.5

* 9 Physical and chemical properties· Information on basic physical and chemical properties· General Information· Appearance:

Form: SolidColor: White

· Odor: Odorless· Odor threshold: Not determined.

· pH-value: 11.5

· Change in conditionMelting point/Melting range: 854 °CBoiling point/Boiling range: 1,600 °C

· Flash point: Not applicableNot determined.

· Flammability (solid, gaseous) Product is not flammable.

· Decomposition temperature: Not determined.

· Auto igniting: Not determined.

· Danger of explosion: Not determined.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapor pressure: Not applicable.

· Density at 20 °C: 2.533 g/cm³

· Bulk density: 500-600 kg/m³· Relative density Not determined.· Vapor density Not applicable.· Evaporation rate Not applicable.

· Solubility in / Miscibility withWater at 20 °C: 212 g/l

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:dynamic: Not applicable.kinematic: Not applicable.

Solids content: 100.0 %· Other information No further relevant information available.

* 10 Stability and reactivity· Reactivity No further relevant information available.





(Contd. of page 4)

51.1.5

· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· LD/LC50 values for hazardous components per OSHA criteria:497-19-8 sodium carbonateOral LD50 4,000 mg/kg (rat)

· Primary irritant effect:· on the skin: Irritant to skin and mucous membranes.· on the eye: Irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:· Carcinogenic categories· IARC (International Agency for Research on Cancer)Substance is not listed.

· NTP (National Toxicology Program)Substance is not listed.

· OSHA-Ca (Occupational Safety & Health Administration)Substance is not listed.

· Target organs: Eye.

* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Assessment by list): slightly hazardous for water.Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.Rinse off of bigger amounts into drains or the aquatic environment may lead to increased pH-values. A high pH-value harmsaquatic organisms. In the dilution of the use-level the pH-value is considerably reduced, so that after the use of the productthe aqueous waste, emptied into drains, is only low water-dangerous.





(Contd. of page 5)

51.1.5

· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· Other adverse effects No further relevant information available.

* 13 Disposal considerations· Waste treatment methods· RecommendationMust not be disposed of together with household garbage. Do not allow product to reach sewage system.Dispose of waste in accordance to applicable national, regional, or local regulations.

· Uncleaned packagings:· Recommendation: Disposal must be made according to official regulations.· Recommended cleansing agent: Water, if necessary with cleansing agents.

* 14 Transport information· UN-Number· DOT, ADR, ADN, IMDG, IATA Not Regulated

· UN proper shipping name· DOT, ADN, IMDG, IATA Not Regulated· ADR Not Regulated

Not Regulated

· Transport hazard class(es)· DOT, ADR, ADN, IMDG, IATA· Class Not Regulated

· Packing group· DOT, ADR, IMDG, IATA Not Regulated

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Not applicable.

· Transport in bulk according to Annex II of MARPOL73/78and the IBC Code Not applicable.

· UN "Model Regulation": Not Regulated US

(Contd. on page 7)




(Contd. of page 6)

51.1.5

* 15 Regulatory information· Safety, health and environmental regulations/legislation specific for the substance or mixture· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)· Section 302/304 (40CFR355.30 / 40CFR355.40):Substance not listed.

· Section 313 (40CFR372.65):Substance is not listed.

· TSCA (Toxic Substances Control Act):ACTIVE

· Hazardous Air PollutantsSubstance is not listed.

· California Proposition 65:· Chemicals known to cause cancer:Substance is not listed.

· Chemicals known to cause reproductive toxicity for females:Substance is not listed.

· Chemicals known to cause reproductive toxicity for males:Substance is not listed.

· Developmental ToxicitySubstance is not listed.

· Carcinogenic categories· EPA (Environmental Protection Agency)Substance is not listed.

· TLV (Threshold Limit Value established by ACGIH)Substance is not listed.

· NIOSH-Ca (National Institute for Occupational Safety and Health)Substance is not listed.

· National regulations· Water hazard class: Water hazard class 1 (Assessment by list): slightly hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

16 Other informationThis information is based on our present knowledge. However, this shall not constitute a guarantee for any specific productfeatures and shall not establish a legally valid contractual relationship.

· Department issuing SDS: Environmental Health and Safety.· Contact:Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000





(Contd. of page 7)

51.1.5

Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000· Date of preparation / last revision 08/03/2020 / -· Abbreviations and acronyms:

ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)LC50: Lethal concentration, 50 percentLD50: Lethal dose, 50 percentPBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit ValuePEL: Permissible Exposure LimitREL: Recommended Exposure LimitEye Irrit. 2A: Serious eye damage/eye irritation – Category 2A

· * Data compared to the previous version altered. US



51.1.5

* 1 Identification· Product identifier· Trade name: Fixative Enhancer Concentrate· Catalog or product number: 1610461, 1610461EDU, 9702046· Application of the substance / the mixture Laboratory chemicals



* 2 Hazard(s) identification· Classification of the substance or mixtureThe product is not classified, according to the Globally Harmonized System (GHS).

· Label elements· GHS label elements Not Applicable· Hazard pictograms Not Applicable· Signal word Not Applicable· Hazard statements Not Applicable· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:56-81-5 glycerol 35-50%

· Additional information For the wording of the listed risk phrases refer to section 15.

* 4 First-aid measures· Description of first aid measures· General information No special measures required.· After inhalation Supply fresh air; consult doctor in case of complaints.· After skin contact Generally the product does not irritate the skin.· After eye contact Rinse opened eye for several minutes under running water.




Trade name: Fixative Enhancer Concentrate

(Contd. of page 1)

51.1.5

· After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.

* 5 Fire-fighting measures· Extinguishing media· Suitable extinguishing agents Use fire fighting measures that suit the environment.· Special hazards arising from the substance or mixture No further relevant information available.· Advice for firefighters· Protective equipment: No special measures required.

* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions: Dilute with plenty of water.· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).

· Reference to other sectionsNo dangerous substances are released.See Section 7 for information on safe handlingSee Section 8 for information on personal protection equipment.See Section 13 for disposal information.

· Protective Action Criteria for Chemicals· PAC-1:glycerol 45 mg/m³

· PAC-2:56-81-5 glycerol 180 mg/m³

· PAC-3:56-81-5 glycerol 1,100 mg/m³


· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.





(Contd. of page 2)

51.1.5

· Specific end use(s) No further relevant information available.


· Control parameters· Components with limit values that require monitoring at the workplace:56-81-5 glycerolPEL Long-term value: 15* 5** mg/m³

mist; *total dust **respirable fractionTLV TLV withdrawn-insufficient data human occup. exp.

· Additional information: The lists that were valid during the creation were used as basis.

· Exposure controls· Personal protective equipment· General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed.· Breathing equipment: Not required.· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

· Eye protection: Safety glasses


Form: LiquidColor: Colorless


· pH-value: Not determined.

· Change in conditionMelting point/Melting range: undeterminedBoiling point/Boiling range: undetermined

· Flash point: > 100 °C

· Flammability (solid, gaseous) Not applicable.

· Ignition temperature: 400 °C


· Auto igniting: Product is not selfigniting.(Contd. on page 4)

US




(Contd. of page 3)

51.1.5


· Explosion limits:Lower: 0.9 Vol %Upper: Not determined.

· Vapor pressure at 20 °C: 23 hPa

· Density at 20 °C: 1.11504 g/cm³· Relative density Not determined.· Vapor density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withWater: Fully miscible


· Viscosity:dynamic: Not determined.kinematic: Not determined.

· Solvent content:Organic solvents: 50.0 %Water: 50.0 %

· Other information No further relevant information available.

* 10 Stability and reactivity· Reactivity No further relevant information available.· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· LD/LC50 values for hazardous components per OSHA criteria:56-81-5 glycerolOral LD50 4,090 mg/kg (mouse)

12,600 mg/kg (rat)Dermal LD50 10,000 mg/kg (Rabbit)Inhalative LC50/4 h >30 mg/l (Rat)





(Contd. of page 4)

51.1.5

· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:When used and handled according to specifications, the product does not have any harmful effects according to ourexperience and the information provided to us.

· Carcinogenic categories· IARC (International Agency for Research on Cancer)None of the ingredients is listed.

· NTP (National Toxicology Program)None of the ingredients is listed.

· OSHA-Ca (Occupational Safety & Health Administration)None of the ingredients is listed.

· Target organs: Not applicable.

* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes: Generally not hazardous for water.· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· Other adverse effects No further relevant information available.



US

(Contd. on page 6)




(Contd. of page 5)

51.1.5



Not Regulated






· Transport/Additional information: Not dangerous according to the above specifications.

· UN "Model Regulation": Not Regulated

* 15 Regulatory information· Safety, health and environmental regulations/legislation specific for the substance or mixture· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)· Section 302/304 (40CFR355.30 / 40CFR355.40):None of the ingredients is listed.

· Section 313 (40CFR372.65):None of the ingredients is listed.

· TSCA (Toxic Substances Control Act):All components have the value ACTIVE.

· Hazardous Air PollutantsNone of the ingredients is listed.

· California Proposition 65:· Chemicals known to cause cancer:The product does not contain listed components.

· Chemicals known to cause reproductive toxicity for females:None of the ingredients is listed.





(Contd. of page 6)

51.1.5

· Chemicals known to cause reproductive toxicity for males:None of the ingredients is listed.

· Developmental ToxicityNone of the ingredients is listed.

· Carcinogenic categories· EPA (Environmental Protection Agency)None of the ingredients is listed.

· TLV (Threshold Limit Value established by ACGIH)None of the ingredients is listed.

· NIOSH-Ca (National Institute for Occupational Safety and Health)None of the ingredients is listed.

· National regulations· Technical instructions (air):

Class Share in %NK 35-50

· Water hazard class: Generally not hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.




ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)LC50: Lethal concentration, 50 percentLD50: Lethal dose, 50 percentPBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit Value





(Contd. of page 7)

51.1.5

PEL: Permissible Exposure LimitREL: Recommended Exposure Limit




51.1.5

1 Identification· Product identifier· Trade name: Silver Complex Solution· Catalog or product number: 1610462, 1610462EDU· Application of the substance / the mixture Laboratory chemicals



* 2 Hazard(s) identification· Classification of the substance or mixtureSkin Irrit. 2 H315 Causes skin irritation.Eye Irrit. 2A H319 Causes serious eye irritation.Aquatic Acute 3 H402 Harmful to aquatic life.Aquatic Chronic 3 H412 Harmful to aquatic life with long lasting effects.

· Label elements· GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).· Hazard pictograms

GHS07

· Signal word Warning· Hazard statementsH315 Causes skin irritation.H319 Causes serious eye irritation.H402 Harmful to aquatic life.H412 Harmful to aquatic life with long lasting effects.

· Precautionary statementsP273 Avoid release to the environment.P280 Wear protective gloves / eye protection / face protection.P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to

do. Continue rinsing.P332+P313 If skin irritation occurs: Get medical advice/attention.P337+P313 If eye irritation persists: Get medical advice/attention.P501 Dispose of contents/container in accordance with local/regional/national/international regulations.




Trade name: Silver Complex Solution

(Contd. of page 1)

51.1.5

· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:6484-52-2 ammonium nitrate Ox. Sol. 1, H271 1-2.5%7761-88-8 silver nitrate Ox. Sol. 2, H272

Skin Corr. 1B, H314Aquatic Acute 1, H400; Aquatic Chronic 1, H410

1-<2.5%


* 4 First-aid measures· Description of first aid measures· General information Immediately remove any clothing soiled by the product.· After inhalation Supply fresh air; consult doctor in case of complaints.· After skin contactGenerally the product does not irritate the skin.Immediately wash with water and soap and rinse thoroughly.Immediately rinse with water.

· After eye contact Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.· After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.


* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions:Do not allow product to reach sewage system or any water course.





(Contd. of page 2)

51.1.5

Inform respective authorities in case of seepage into water course or sewage system.Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).Dispose contaminated material as waste according to item 13.

· Reference to other sectionsSee Section 7 for information on safe handlingSee Section 8 for information on personal protection equipment.See Section 13 for disposal information.

· Protective Action Criteria for Chemicals· PAC-1:ammonium nitrate 6.7 mg/m³silver nitrate 0.047 mg/m³

· PAC-2:6484-52-2 ammonium nitrate 73 mg/m³7761-88-8 silver nitrate 0.9 mg/m³

· PAC-3:6484-52-2 ammonium nitrate 440 mg/m³7761-88-8 silver nitrate 5.4 mg/m³



8 Exposure controls/personal protection· Additional information about design of technical systems: No further data; see item 7.

· Control parameters· Components with limit values that require monitoring at the workplace:The product does not contain any relevant quantities of materials with critical values that have to be monitored at theworkplace.

· Additional information: The lists that were valid during the creation were used as basis.(Contd. on page 4)

US




(Contd. of page 3)

51.1.5


· Breathing equipment: Not necessary if room is well-ventilated. Adequate ventilation required.· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.





· pH-value at 20 °C: 3.7

· Change in conditionMelting point/Melting range: 0 °CBoiling point/Boiling range: 100 °C

· Flash point: Not applicableNot determined.



· Auto igniting: Product is not selfigniting.




· Density at 20 °C: 1.02435 g/cm³· Relative density Not determined.





(Contd. of page 4)

51.1.5

· Vapor density Not determined.· Evaporation rate Not determined.




· Solvent content:Water: 96.0 %



* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· Primary irritant effect:· on the skin: Irritant to skin and mucous membranes.· on the eye: Irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:The product shows the following dangers according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:Irritant







(Contd. of page 5)

51.1.5



* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Ecotoxical effects:· Remark: Harmful to fish· Additional ecological information:· General notes:Water hazard class 2 (Self-assessment): hazardous for water.Do not allow product to reach ground water, water course or sewage system.Danger to drinking water if even small quantities leak into the ground.Harmful to aquatic organisms






Not Regulated(Contd. on page 7)

US




(Contd. of page 6)

51.1.5








· Section 313 (40CFR372.65):6484-52-2 ammonium nitrate7761-88-8 silver nitrate












(Contd. of page 7)

51.1.5



· National regulations· Water hazard class: Water hazard class 2 (Self-assessment): hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.




ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit ValuePEL: Permissible Exposure LimitREL: Recommended Exposure LimitOx. Sol. 1: Oxidizing solids – Category 1Ox. Sol. 2: Oxidizing solids – Category 2Skin Corr. 1B: Skin corrosion/irritation – Category 1BSkin Irrit. 2: Skin corrosion/irritation – Category 2Eye Irrit. 2A: Serious eye damage/eye irritation – Category 2AAquatic Acute 1: Hazardous to the aquatic environment - acute aquatic hazard – Category 1Aquatic Acute 3: Hazardous to the aquatic environment - acute aquatic hazard – Category 3Aquatic Chronic 1: Hazardous to the aquatic environment - long-term aquatic hazard – Category 1Aquatic Chronic 3: Hazardous to the aquatic environment - long-term aquatic hazard – Category 3




51.1.5

1 Identification· Product identifier· Trade name: Reduction Moderator Solution· Catalog or product number: 1610463, 1610463EDU, 9702048· Application of the substance / the mixture Laboratory chemicals



* 2 Hazard(s) identification· Classification of the substance or mixtureSkin Irrit. 2 H315 Causes skin irritation.Eye Irrit. 2A H319 Causes serious eye irritation.


GHS07

· Signal word Warning· Hazard statementsH315 Causes skin irritation.H319 Causes serious eye irritation.

· Precautionary statementsP264 Wash thoroughly after handling.P280 Wear protective gloves / eye protection / face protection.P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to

do. Continue rinsing.P332+P313 If skin irritation occurs: Get medical advice/attention.P362+P364 Take off contaminated clothing and wash it before reuse.P337+P313 If eye irritation persists: Get medical advice/attention.

· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.




Trade name: Reduction Moderator Solution

(Contd. of page 1)

51.1.5

· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:12027-43-9 Tungstosilicic acid hydrate Skin Irrit. 2, H315; Eye Irrit. 2A, H319; STOT SE 3, H335 10%


* 4 First-aid measures· Description of first aid measures· General information Immediately remove any clothing soiled by the product.· After inhalation Supply fresh air; consult doctor in case of complaints.· After skin contactGenerally the product does not irritate the skin.Immediately wash with water and soap and rinse thoroughly.Immediately rinse with water.

· After eye contact Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.· After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.


* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).






(Contd. of page 2)

51.1.5

· Protective Action Criteria for Chemicals· PAC-1:None of the ingredients is listed.

· PAC-2:None of the ingredients is listed.

· PAC-3:None of the ingredients is listed.




· Control parameters· Components with limit values that require monitoring at the workplace:The product does not contain any relevant quantities of materials with critical values that have to be monitored at theworkplace.



· Breathing equipment: Not necessary if room is well-ventilated. Adequate ventilation required.· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

· Eye protection:Safety glasses





(Contd. of page 3)

51.1.5

Tightly sealed goggles.




· pH-value at 20 °C: 2.1

· Change in conditionMelting point/Melting range: undeterminedBoiling point/Boiling range: 100 °C

· Flash point: Not applicable







· Density: Not determined· Relative density Not determined.· Vapor density Not determined.· Evaporation rate Not determined.




· Solvent content:Water: 90.0 %

Solids content: 10.0 %(Contd. on page 5)

US




(Contd. of page 4)

51.1.5

· Other information No further relevant information available.


* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· Primary irritant effect:· on the skin: Irritant to skin and mucous membranes.· on the eye: Irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:The product shows the following dangers according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:Irritant





* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.





(Contd. of page 5)

51.1.5

· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.


13 Disposal considerations· Waste treatment methods· RecommendationMust not be disposed of together with household garbage. Do not allow product to reach sewage system.Dispose of waste in accordance to applicable national, regional, or local regulations.




Not Regulated






· UN "Model Regulation": Not Regulated US

(Contd. on page 7)




(Contd. of page 6)

51.1.5


· Section 313 (40CFR372.65):None of the ingredients is listed.

· TSCA (Toxic Substances Control Act):7732-18-5 water ACTIVE









· National regulations· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.







(Contd. of page 7)

51.1.5


ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit ValuePEL: Permissible Exposure LimitREL: Recommended Exposure LimitSkin Irrit. 2: Skin corrosion/irritation – Category 2Eye Irrit. 2A: Serious eye damage/eye irritation – Category 2ASTOT SE 3: Specific target organ toxicity (single exposure) – Category 3




51.1.5

1 Identification· Product identifier· Trade name: Image Development Reagent· Catalog or product number: 1610464, 1610464EDU· Application of the substance / the mixture Laboratory chemicals



* 2 Hazard(s) identification· Classification of the substance or mixtureSkin Sens. 1 H317 May cause an allergic skin reaction.Muta. 2 H341 Suspected of causing genetic defects.Carc. 1B H350 May cause cancer.


GHS07 GHS08

· Signal word Danger

· Hazard-determining components of labeling:formaldehyde

· Hazard statementsH317 May cause an allergic skin reaction.H341 Suspected of causing genetic defects.H350 May cause cancer.

· Precautionary statementsP261 Avoid breathing dust/fume/gas/mist/vapors/sprayP280 Wear protective gloves/protective clothing/eye protection/face protection.P308+P313 IF exposed or concerned: Get medical advice/attention.P363 Wash contaminated clothing before reuse.P405 Store locked up.P501 Dispose of contents/container in accordance with local/regional/national/international regulations.




Trade name: Image Development Reagent

(Contd. of page 1)

51.1.5

· Emergency overview:· Routes of exposure:IngestionInhalationSkin

· Classification system· Special Hazards Carcinogen.· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Substances· CAS No. Description:7732-18-5 water

· Identification number(s):· EC number: 231-791-2· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:50-00-0 formaldehyde Acute Tox. 3, H301; Acute Tox. 3, H311; Acute Tox. 3, H331

Muta. 2, H341; Carc. 1B, H350Skin Corr. 1B, H314Skin Sens. 1, H317Flam. Liq. 4, H227

2.5-<5%


* 4 First-aid measures· Description of first aid measures· General information No special measures required.· After inhalationSupply fresh air and to be sure call for a doctor.In case of unconsciousness place patient stably in side position for transportation.

· After skin contactImmediately wash with water and soap and rinse thoroughly.Immediately rinse with water.

· After eye contact Rinse opened eye for several minutes under running water.· After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.

US

(Contd. on page 3)




(Contd. of page 2)

51.1.5


* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).Dispose contaminated material as waste according to item 13.Ensure adequate ventilation.


· Protective Action Criteria for Chemicals· PAC-1:formaldehyde 0.90 ppm

· PAC-2:50-00-0 formaldehyde 14 ppm

· PAC-3:50-00-0 formaldehyde 56 ppm

* 7 Handling and storage· Handling· Precautions for safe handlingEnsure good ventilation/exhaust at the workplace.Open and handle receptacle with care.Prevent formation of aerosols.

· Information about protection against explosions and fires: Keep respiratory protective device available.

· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: Keep receptacle tightly sealed.





(Contd. of page 3)

51.1.5

· Specific end use(s) No further relevant information available.


· Control parameters· Components with limit values that require monitoring at the workplace:50-00-0 formaldehydePEL Short-term value: 2 ppm

Long-term value: 0.75 ppmsee 29 CFR 1910.1048(c)

REL Long-term value: 0.016 ppmCeiling limit value: 0.1* ppm*15-min; See Pocket Guide App. A

TLV Short-term value: 0.37 mg/m³, 0.3 ppmLong-term value: 0.12 mg/m³, 0.1 ppmDSEN; RSEN


· Exposure controls· Personal protective equipment· General protective and hygienic measuresKeep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.Store protective clothing separately.Avoid contact with the skin.

· Breathing equipment:In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratoryprotective device that is independent of circulating air.Not necessary if room is well-ventilated. Adequate ventilation required.

· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.



Form: Liquid(Contd. on page 5)

US




(Contd. of page 4)

51.1.5

Color: Colorless· Odor: Odorless· Odor threshold: Not determined.

· pH-value: Not determined.

· Change in conditionMelting point/Melting range: 0 °CBoiling point/Boiling range: 100 °C

· Flash point: Not applicable




· Danger of explosion: Product does not present an explosion hazard.



· Density at 20 °C: 0.99347 g/cm³· Relative density Not determined.· Vapor density Not determined.· Evaporation rate Not determined.



· Viscosity:dynamic at 20 °C: 0.952 mPaskinematic: Not determined.

· Solvent content:Organic solvents: 2.8 %Water: 97.2 %


* 10 Stability and reactivity· Reactivity No further relevant information available.· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.





(Contd. of page 5)

51.1.5

· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· LD/LC50 values for hazardous components per OSHA criteria:50-00-0 formaldehydeOral LD50 >200 mg/kg (rat)

· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritant effect.· Sensitization: Sensitization possible through skin contact.· Additional toxicological information:The product shows the following dangers according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:Irritant

· Carcinogenic categories· IARC (International Agency for Research on Cancer)50-00-0 formaldehyde 1

· NTP (National Toxicology Program)50-00-0 formaldehyde K

· OSHA-Ca (Occupational Safety & Health Administration)50-00-0 formaldehyde

· Target organs: Skin.

* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.


US

(Contd. on page 7)




(Contd. of page 6)

51.1.5




· UN proper shipping name· DOT, ADR, ADN, IMDG, IATA Not Regulated







* 15 Regulatory information· Safety, health and environmental regulations/legislation specific for the substance or mixture· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)· Section 302/304 (40CFR355.30 / 40CFR355.40):50-00-0 formaldehyde

· Section 313 (40CFR372.65):50-00-0 formaldehyde






(Contd. of page 7)

51.1.5

· Hazardous Air Pollutants50-00-0 formaldehyde

· California Proposition 65:· Chemicals known to cause cancer:50-00-0 formaldehyde




· Carcinogenic categories· EPA (Environmental Protection Agency)50-00-0 formaldehyde B1

· TLV (Threshold Limit Value established by ACGIH)50-00-0 formaldehyde A2

· NIOSH-Ca (National Institute for Occupational Safety and Health)50-00-0 formaldehyde

· National regulations· Information about limitation of use:Workers are not allowed to be exposed to the hazardous carcinogenic materials contained in this preparation. Exceptionscan be made by the authorities in certain cases.

· Technical instructions (air):Class Share in %

I 2.5-<5

· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.



Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000· Date of preparation / last revision 08/03/2020 / -





(Contd. of page 8)

51.1.5

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)LC50: Lethal concentration, 50 percentLD50: Lethal dose, 50 percentPBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit ValuePEL: Permissible Exposure LimitREL: Recommended Exposure LimitFlam. Liq. 4: Flammable liquids – Category 4Acute Tox. 3: Acute toxicity – Category 3Skin Corr. 1B: Skin corrosion/irritation – Category 1BSkin Sens. 1: Skin sensitisation – Category 1Muta. 2: Germ cell mutagenicity – Category 2Carc. 1B: Carcinogenicity – Category 1B


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08/03/2020 Kit Components Product code Description

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