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INTRODUCTIONINTRODUCTION

DEPARTMENT OF NUCLEAR MEDICINEDEPARTMENT OF NUCLEAR MEDICINE

REN-JI HOSPITAL REN-JI HOSPITAL

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Nuclear MedicineNuclear Medicine

ConceptConceptNuclear Medicine is the science Nuclear Medicine is the science which use radioisotopes to which use radioisotopes to diagnose or treatment of disease. diagnose or treatment of disease.

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Characteristics of Nuclear Characteristics of Nuclear MedicineMedicine

Nuclear medicine imaging provides doctors with Nuclear medicine imaging provides doctors with

information about both structure and function. information about both structure and function.

It is a way to gather medical information that would It is a way to gather medical information that would

otherwise be unavailable, require surgery, or otherwise be unavailable, require surgery, or

necessitate more expensive diagnostic tests. necessitate more expensive diagnostic tests.

Nuclear medicine imaging procedures often identify Nuclear medicine imaging procedures often identify

abnormalities very early in the progress of a disease—abnormalities very early in the progress of a disease—

long before many medical problems are apparent with long before many medical problems are apparent with

other diagnostic tests. other diagnostic tests.

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Nuclear Medicine in modern CliNuclear Medicine in modern Clinical Medicine and Research nical Medicine and Research

Today, nuclear medicine offers procedures that are essential in many medical specialties, from pediatrics to cardiology to psychiatry. New and innovative nuclear medicine treatments that target and pinpoint molecular levels within the body are revolutionizing our understanding of and approach to a range of diseases and conditions.

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Classification of Nuclear MediciClassification of Nuclear Medicine. ne.

Nuclear Medicine imaging.Nuclear Medicine imaging. In vivo function testIn vivo function test ImmunoassayImmunoassay Radionuclide Therapy Radionuclide Therapy

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Nuclear Medicine imagingNuclear Medicine imaging

Process whereby a radionuclide is injected or measured (through tissue) from an external source, and a display is obtained from any one of several rectilinear scanner or gamma camera systems.

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Classified by imaging timeClassified by imaging time

Static DynamicStatic Dynamic

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Local Whole bodyLocal Whole body

Classified by imaging part Classified by imaging part

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Classified by imaging methoClassified by imaging method d

Planar TomographyPlanar Tomography

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Classified by lesion uptakeClassified by lesion uptakePositive imaging Negative imagingPositive imaging Negative imaging

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Functional StudyFunctional Study

Thyroid uptake testThyroid uptake testRenogramRenogram

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ImmunoassayImmunoassay

It’s a technique to detect micro substances in It’s a technique to detect micro substances in body fluid. body fluid.

This technique has been developed in 1959 by SThis technique has been developed in 1959 by Solomen Berson and Rosalyn Yalow in Bronx, Neolomen Berson and Rosalyn Yalow in Bronx, New York. For their contribution of this important w York. For their contribution of this important analytical technique to medical science, R. Yoloanalytical technique to medical science, R. Yolow and Berson shared the Nobel price in Medicinw and Berson shared the Nobel price in Medicine and physiology in 1977.e and physiology in 1977.

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Radionuclide Therapy Radionuclide Therapy

Internal IrradiationInternal Irradiation Contact IrradiationContact Irradiation Intracavitary IrradiationIntracavitary Irradiation Interstitial IrradiationInterstitial Irradiation

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The History of Nuclear The History of Nuclear MedicineMedicine

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French Physicist discovered radFrench Physicist discovered radioactivity in 1896 ioactivity in 1896

Henri Becquerel(1852-1908)

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German physicist who discoverGerman physicist who discovered X-rays in 1895 ed X-rays in 1895

Wilhelm Röentgen(1845-1923)

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French physicist who, along with hiFrench physicist who, along with his wife Marie Sklodowska Curie, isols wife Marie Sklodowska Curie, isolated polonium and radium in 1898ated polonium and radium in 1898

Pierre Curie(1859-1906)

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American physicist who won the 19American physicist who won the 1939 Nobel Prize in physics for the inv39 Nobel Prize in physics for the invention of the cyclotronention of the cyclotron

Ernest O. Lawrence (1901-1958)

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American inventor of the scintillatiAmerican inventor of the scintillation scanning camera in 1958.on scanning camera in 1958.

Hal Anger

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Nuclear Medicine is the major Nuclear Medicine is the major technique in molecular technique in molecular imagingimaging