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INTRODUCTION TO THEENDOCRINE SYSTEM
Prof. Dr. Ieva B Akbar, dr., AIF.
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Hormone Hormone Have Been !no"n S#n$e An$#en% %#me
&'a% Make a C'em#$a( a Hormone)
Hormone Are Se$re%ed b* a Ce(( or +ro- of Ce(( Hormone Are Se$re%ed #n %o %'e B(ood
Hormone Are Tran-or%ed %o a D#%an% Tare%
Hormone A$% b* B#nd#n %o Re$e-%or
Hormone A$%#on M% Be Term#na%ed
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T'e C(a#f#$a%#on Of Hormone Mo% Hormone Are Pe-%#de or Pro%e#n
Pe-%#de Hormone S*n%'e#, S%orae, and Re(eae
Po%/Tran(a%#ona( Mod#f#$a%#on of Pro'ormone Tran-or% #n %'e B(ood and Ha(f/0#fe of Pe-%#de
Ce(((ar Me$'an#m of A$%#on of Pe-%#de Hormone
S%ero#d Hormone Are Der#ved from C'o(e%ero(
S%ero#d Hormone S*n%'e# and Re(eae
Tran-or% #n %'e B(ood and Ha(f/0#fe of S%ero#d Hormone
Ce(((ar Me$'an#m of A$%#on of S%ero#d Hormone
Am#ne Hormone Are Der#ved from One of T"o Am#no A$#d
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Con%ro( Of Hormone Re(eae Hormone Can Be C(a#f#ed b* T'e#r Ref(e1 Pa%'"a*
T'e Endo$r#ne Ce(( I %'e Senor #n %'e S#m-(e% Endo$r#ne Ref(e1e
Man* Endo$r#ne Ref(e1e Invo(ve %'e Nervo S*%em
Nero'ormone Are Se$re%ed #n%o %'e B(ood b* Neron
T'e P#%#%ar* +(and # A$%a((* T"o Fed +(and T'e Po%er#or P#%#%ar* S%ore and Re(eae T"o Nero'ormone
T'e An%er#or P#%#%ar* Se$re%e S#1 Hormone
Feedba$k 0oo- Are D#fferen% #n %'e H*-o%'a(am#$/P#%#%ar* Pa%'"a*
T'e H*-o%'a(am#$/H*-o-'*ea( Por%a( S*%em D#re$% Tro-'#$ Hormone De(#ver*
An%er#or P#%#%ar* Hormone Con%ro( +ro"%', Me%abo(#m, and Re-rod$%#on
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Hormone In%era$%#on In S*ner#m, %'e Effe$% of In%era$%#n Hormone
I More T'an Add#%#ve
A Perm##ve Hormone A((o" Ano%'er Hormone
%o E1er% I% F(( Effe$%
An%aon#%#$ Hormone Have O--o#n Effe$%
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Endo$r#ne Pa%'o(o#e H*-ere$re%#on E1aera%e a Hormone2 Effe$%
H*-oe$re%#on D#m#n#'e or E(#m#na%e a Hormone2 Effe$%
Re$e-%or or Se$ond Meener Prob(em Cae Abnorma(T#e Re-on#vene
Do"n/Re(a%#on
Re$e-%or an S#na( Trand$%#on Abnorma(#%#e
D#ano# of Endo$r#ne Pa%'o(o#e De-end on %'e
Com-(e1#%* of %'e Ref(e1
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Ter#ma !a#'
