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1 Lupin Limited Corporate Presentation November 2007.

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1 Lupin Limited Corporate Presentation November 2007
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Page 1: 1 Lupin Limited Corporate Presentation November 2007.

1

Lupin LimitedCorporate Presentation

November 2007

Page 2: 1 Lupin Limited Corporate Presentation November 2007.

2

Safe Harbour StatementSafe Harbour Statement

Materials and information provided during this presentation may contain ‘forward-looking statements’. These statements are based on current expectations, forecasts and assumptions that are subject to risks and uncertainties which could cause actual outcomes and results to differ materially from these statements.

Risks and uncertainties include general industry and market conditions, and general domestic and international economic conditions such as interest rate and currency exchange fluctuations. Risks and uncertainties particularly apply with respect to product-related forward-looking statements. Product risks and uncertainties include, but are not limited, to technological advances and patents attained by competitors, challenges inherent in new product development, including completion of clinical trials; claims and concerns about product safety and efficacy; obtaining regulatory approvals; domestic and foreign healthcare reforms; trends toward managed care and healthcare cost containment, and governmental laws and regulations affecting domestic and foreign operations.

Also, for products that are approved, there are manufacturing and marketing risks and uncertainties, which include, but are not limited, to inability to build production capacity to meet demand, unavailability of raw materials, and failure to gain market acceptance.

The Company disclaims any intention or obligation to update or revise any forward-looking statements whether as a result of new information, future events or otherwise.

Page 3: 1 Lupin Limited Corporate Presentation November 2007.

3

Introduction . . .Introduction . . .

Section 1Section 1

Page 4: 1 Lupin Limited Corporate Presentation November 2007.

4

VisionVision

• To be an Innovation-led Transnational Pharmaceutical Company

ValuesValues

• Superior Performance

• Entrepreneurship

• Customer Orientation

• Working Together

• Respect for People

• Integrity

Page 5: 1 Lupin Limited Corporate Presentation November 2007.

5

ContentsContents

– Global Pharmaceutical Industry Overview– Indian Pharmaceutical Industry– Lupin -Business Update

Page 6: 1 Lupin Limited Corporate Presentation November 2007.

Pharmaceutical Industry OverviewPharmaceutical Industry Overview

Section 2Section 2

Page 7: 1 Lupin Limited Corporate Presentation November 2007.

7

Global Pharmaceutical Industry OverviewGlobal Pharmaceutical Industry Overview

Global Pharmaceutical market at about US$650 billion market in 2006

Market expected to grow at a rate of 6-7%Ten major markets account for over 80% of the market in terms of revenue

Expected to experience growth ranging between 5-8%Growing importance of generics in regulated markets

Pressure from healthcare providers and insurance companies to reduce healthcare costs driving usage of generic drugs

Increasing patent expirations driving generic drug availabilityIncreasing healthcare spend in emerging markets

Advancement in infrastructure

Awareness and affordability

Longevity

Page 8: 1 Lupin Limited Corporate Presentation November 2007.

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Indian Pharma – Emerging ScenarioIndian Pharma – Emerging Scenario

DOMESTIC FORMULATIONS

IPR RegimeAccent on Brand buildingExperiencing high growthPartnerships

Contract Mfg (API + FD)

•Cost Quality Leadership•JV/ Alliances

INDIGENOUS R&D

• ANDA/NDDS/NCE• Out Licensing

GENERICS BUSINESS

• Pricing pressure Aggressive build up of products Cost, Quality, Regulatory knowhow

Domestic Market: US$ 5.5bn Exports: US$ 3.0bn Total: US$ 8.5bn

Indian Pharma

Page 9: 1 Lupin Limited Corporate Presentation November 2007.

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ApproachApproach

Section 3Section 3

Page 10: 1 Lupin Limited Corporate Presentation November 2007.

10

Lupin’s Business ModelLupin’s Business Model

Technology

•ANDA / NDDS

•Vertical Integration

•NCE

Alliances

•JV in select markets

•Long term partnership with customers

•In-Licensing

Sustainable Earnings

Accelerated Growth

Fulfilling Stakeholder Aspirations

Sustainable Earnings

Accelerated Growth

Fulfilling Stakeholder Aspirations

Markets

•US: Generic and Branded (Paediatric) marketing

•Geographical Expansion

• Enhance market penetration

Page 11: 1 Lupin Limited Corporate Presentation November 2007.

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Advanced MarketsAdvanced Markets

Section 4Section 4

Page 12: 1 Lupin Limited Corporate Presentation November 2007.

12

Advanced Markets: Lupin ApproachAdvanced Markets: Lupin Approach

Branded

•NDDS

•Promotion Strategy

•Brand Life Management

Generics

•Products•Vertical integration•Para IV

•Trade•Fill Rates & Service•Quality •Competitive Price

Partnered

•Physicians Office

•Hospitals

Page 13: 1 Lupin Limited Corporate Presentation November 2007.

13

USUS

Branded Suprax continues strong growth: over 8500Rx per week in peak season Launched Line extension : Suprax DS

Generics 6 products launched in the US in FY07 Market share as indicated by IMS data:

Lisinopril – 33 % - Market Leader Cefprozil Tabs – 25 % Cefprozil Susp – 25 % Among top 3 in each segment in MS terms

Cefdinir: Complete range launched Over 50 ANDA’s filed; 20 approved to date

Page 14: 1 Lupin Limited Corporate Presentation November 2007.

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Other Advanced MarketsOther Advanced Markets

Europe• Cefpodoxime Proxetil: Approval for France • Ramping up MAA/ Dossier filings • Alliances in progress

• Revenues commenced

• Product launches to begin in mid FY08Japan• Acquisition of Kyowa

• Among the top 10 generic pharma companies

Australia & LA• Expressions of interest moving forward• MDR-TB sales commenced in LASouth Africa• Aspen (Anti-TB FDC) for Africa

Page 15: 1 Lupin Limited Corporate Presentation November 2007.

15

Robust pipelineRobust pipeline

Country Total submissions

US 51

EU 24

Australia/ NZ 20

Page 16: 1 Lupin Limited Corporate Presentation November 2007.

16

Emerging MarketsEmerging MarketsSection 5Section 5

Page 17: 1 Lupin Limited Corporate Presentation November 2007.

17

Emerging Markets: India Region - Lupin ApproachEmerging Markets: India Region - Lupin Approach

Critical

•Enhanced Focus

•Niche Intensive Therapies

•Super-Specialty

Acute

•Innovation

•Leadership

Acute

•Innovation

•Leadership

Chronic

•New Products

•New Therapies

•Exponential Growth

Chronic

•New Products

•New Therapies

•Exponential Growth

In-licensing

•Marketing

•Distribution

In-licensing

•Marketing

•Distribution

Rural

•Reach

•Penetration

Rural

•Reach

•Penetration

Page 18: 1 Lupin Limited Corporate Presentation November 2007.

18

India RegionIndia Region

• 30% in FY07 (14 % Industry IMS Mar 07 MAT) FY06 Growth 23% vs 7-8% industry average

• Anti-Asthma range launched in Aug 04, already number 2 in its segment and growing (80%+)

• Lupenox (Enoxaparin), Eugraf (EGF): In-licensed• Lupinova driving foray into rural and less penetrated regions • Top 8 brands

Rs. Mn. YTD Mar 07

Tonact 415 R-Cinex 364

AKT 325 Rablet 237

Odoxil 231 Ramistar 201

Ceff 196 L-Cin 191

Page 19: 1 Lupin Limited Corporate Presentation November 2007.

19

Emerging Markets : Others - Lupin ApproachEmerging Markets : Others - Lupin Approach

Branded Generics

•Registrations

•NDDS

•On-shore Presence

Branded Generics

•Registrations

•NDDS

•On-shore Presence

Institutional

•Approved Facilities

•Economies of Scale

Institutional

•Approved Facilities

•Economies of Scale

Page 20: 1 Lupin Limited Corporate Presentation November 2007.

20

Other Emerging MarketsOther Emerging Markets

CIS• Posted a healthy growth – 69%• Expanding Field Force –

• Russia, Ukraine, Azerbaijan, Kazakhstan, Uzbekistan

• Increased market penetration• Around 20 Products Registered in each; around 10 under RegistrationMiddle East• Will be shared as Alliances progress Africa• Alliance with RanbaxyLATAM• Revenues commenced in PeruGTB• Continues steady growth – 24%

Page 21: 1 Lupin Limited Corporate Presentation November 2007.

21

API & IntermediatesAPI & Intermediates

Section 6Section 6

Page 22: 1 Lupin Limited Corporate Presentation November 2007.

22

API & IntermediatesAPI & Intermediates

• One of the most profitable API business in Indian Pharma

– Robust operating performance

– ROCE comparable to the best in the segment

• Focus on Cost & Quality Leadership and Reliability

• Effective asset utilization

• Sustained revenues and profits

• Efforts on to widen therapeutic presence

– Acquisition of Rubamin provides a step up to the CRAMS initiatives

– OABBs growing

• Strategic input to formulations business

– About 70% backward integration

• Global Leadership in chosen therapies

Page 23: 1 Lupin Limited Corporate Presentation November 2007.

23

API & IntermediatesAPI & Intermediates

1Cephalosporin - Intermediate7ADCA

1CardiovascularLisinopril

1Cephalosporin - Intermediate7ACCA

1Anti-TBPyrazinamide

1Anti-TBRifampicin

1Anti-TBEthambutol

Global RankTherapeutic SegmentProduct

Page 24: 1 Lupin Limited Corporate Presentation November 2007.

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Research & DevelopmentResearch & Development

Section 7Section 7

Page 25: 1 Lupin Limited Corporate Presentation November 2007.

25

R&DR&D

• Over 400 scientists

• Expenditure (FY0607) : Rs.1359mn – 6.7% of Sales

– Continue investing incrementally

• IP Generation: Commercial potential– Perindopril IP sale

• Research Interests

– NDDS platforms

– Products of Paediatrics range

– ANDAs

– NCEs• Anti Migraine - In Phase III

• Anti Psoriasis (Chemical) - In Phase II

• Anti Psoriasis (Herbal) - Completed Phase II

• Anti TB - In Phase I

Page 26: 1 Lupin Limited Corporate Presentation November 2007.

26

PatentsPatents

Patents Issued, Allowed & Pending557

Issued, Allowed 70

Pending487

US15

EU

RoW44

EU11

US52

EU38

RoW397

Page 27: 1 Lupin Limited Corporate Presentation November 2007.

27

Business UpdateBusiness Update

Section 8Section 8

Page 28: 1 Lupin Limited Corporate Presentation November 2007.

28

2006-072006-07

8896 106867714 9603

16610

20289

0

5000

10000

15000

20000

25000

Domestic Exports Total

2005-06 2006-07

20%24%

22%

(Rs

Mn)

Sales Growth

Fml Ind37%

Fml Reg16%

API SR18%

API Reg6%

API Ind15%

Fml SR8%

Revenue Composition

Page 29: 1 Lupin Limited Corporate Presentation November 2007.

29

• Revenue Growth : 22%

• EBITDA margin : 24%

• PBT % : 20%

• PAT % : 15%

• ROCE % : 32 %

1827

30213009

4802

0

1000

2000

3000

4000

5000

Net Profit EBITDA

2005-06 2006-07

60%(R

s M

n)

Profit Growth

65%

2006-072006-07

Page 30: 1 Lupin Limited Corporate Presentation November 2007.

30

CoverageCoverage

Geographic Therapeutic

Anti Asthma3%

Anti Diabetics2%

Others19%

Cephs33%

NSAIDS2%

CVS18%

Anti TB20%

GI3%

Exports46%

Domestic54%

API vs FD

FD61%

API39%

Page 31: 1 Lupin Limited Corporate Presentation November 2007.

31

10120

12669

0

2000

4000

6000

8000

10000

12000

14000

Sales

H1 FY0607 H1 FY0708

1055

1314

0

200

400

600

800

1000

1200

1400

Net Income

H1 FY0607 H1 FY0708

2007-08 – H1(R

s M

n)

25%

25%

(Rs

Mn)

*Sales and Net income at Consolidated level

Page 32: 1 Lupin Limited Corporate Presentation November 2007.

32

Facilities Facilities

Section 9Section 9

Page 33: 1 Lupin Limited Corporate Presentation November 2007.

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Lupin’s FacilitiesLupin’s Facilities

Manufacturing

Research Center

Goa

Pune

Tarapur

Ankleshwar

Mandideep

Aurangabad

JammuLOCATION PRODUCTS APPROVALS

Mandideep,

Madhya Pradesh

Cephalosporins

Prils

USFDA, UK MHRA, TGA

USFDA

Tarapur,

Maharashtra

Rifampicin

Lovastatin

USFDA, UK MHRA

-

Ankleshwar,

Gujarat

Ethambutol

Intermediates

USFDA

USFDA

Aurangabad,

Maharashtra

Rifampicin

Pyrazinamide

Ethambutol

Lisinopril

WHO, MCC (South Africa)

WHO, MCC (South Africa)

WHO, MCC (South Africa)

WHO, MCC (South Africa)

Verna,

Goa

Non-cephalosporin Oral Formulations

USFDA, UK MHRA

Jammu,

J&K

Formulations -

Pune, Maharashtra

R&D

Mumbai,

Maharashtra

Head OfficeHead Office

Mumbai

Page 34: 1 Lupin Limited Corporate Presentation November 2007.

34

Year 2007-08 and Beyond . . .Year 2007-08 and Beyond . . .

Section 11Section 11

Page 35: 1 Lupin Limited Corporate Presentation November 2007.

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Going ForwardGoing Forward

New Markets/ Initiatives

• Enter Advanced Markets EU Japan Australia South Africa

• Establish On-shore presence in 5 select markets

• Acquisition: Brands in US Businesses in select countries of EU Domestic

Explore New Therapies/ Business Segments

Page 36: 1 Lupin Limited Corporate Presentation November 2007.

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Thank youThank you


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