1

“Programmed” Self-

Assembly

Hierarchical assembly-

molecules to mammals

2

Routes to Nanoassembly

Sean A. Davis, Michael Breulmann, Katja H. Rhodes, Baojian Zhang, and Stephen Mann “Template-Directed Assembly Using Nanoparticle Building Blocks: A Nanotectonic Approach

to Organized Materials” Chem. Mater., 13 (10), 3218 -3226, 2001.

3

Matrix Confinement

• Diatoms – natural matrix confinement assembly

4

Status Report on Hierarchical, “Programmed” Assembly

Murali Sastry, Mala Rao, and Krishna N. Ganesh “Electrostatic Assembly of Nanoparticles and Biomacromolecules” Acc. Chem. Res., 35 (10), 847 -855, 2002.

5

Programmed Assembly

Chad A. Mirkin “Programming the Assembly of Two- and Three-Dimensional Architectures with DNA and Nanoscale Inorganic Building Blocks” Inorg. Chem., 39 (11), 2258 -2272,

2000.

6

Programmed Assembly

Chad A. Mirkin “Programming the Assembly of Two- and Three-Dimensional Architectures with DNA and Nanoscale Inorganic Building Blocks” Inorg. Chem., 39 (11), 2258 -2272,

2000.

7

Programmed Assembly

Alexander Kulak, Sean A. Davis, Erik Dujardin, and Stephen Mann “Controlled Assembly of Nanoparticle-Containing Gold and Silica Microspheres and Silica/Gold Nanocomposite

Spheroids with Complex Form” Chem. Mater., 15 (2), 528 -535, 2003.

8

Programmed Assembly

Alexander Kulak, Sean A. Davis, Erik Dujardin, and Stephen Mann “Controlled Assembly of Nanoparticle-Containing Gold and Silica Microspheres and Silica/Gold Nanocomposite

Spheroids with Complex Form” Chem. Mater., 15 (2), 528 -535, 2003.

9

Programmed Assembly

Alexander Kulak, Sean A. Davis, Erik Dujardin, and Stephen Mann “Controlled Assembly of Nanoparticle-

Containing Gold and Silica Microspheres and Silica/Gold Nanocomposite Spheroids with Complex Form” Chem.

Mater., 15 (2), 528 -535, 2003.

10

Programmed Assembly

Kensuke Naka, Hideaki Itoh, and Yoshiki Chujo “Temperature-Dependent Reversible Self-Assembly of Gold Nanoparticles into Spherical Aggregates by Molecular Recognition

between Pyrenyl and Dinitrophenyl Units” Langmuir, 19 (13), 5496 -5501, 2003.

11

Programmed Assembly

Hannes Spillmann, Alexandre Dmitriev, Nian Lin, Paolo Messina, Johannes V. Barth, and Klaus Kern “Hierarchical Assembly of Two-Dimensional Homochiral Nanocavity Arrays” J.

Am. Chem. Soc., 125 (35), 10725 -10728, 2003.

12

Programmed Assembly

Stephen Fullam, S. Nagaraja Rao, and Donald Fitzmaurice “Noncovalent Self-Assembly of Silver Nanocrystal Aggregates in Solution” J.Phys. Chem. B, 104 (26), 6164 -6173, 2000.

13

Programmed Assembly

Stephen Fullam, Hakan Rensmo, S. Nagaraja Rao, and Donald Fitzmaurice “Noncovalent Self-Assembly of Silver

and Gold Nanocrystal Aggregates in Solution” Chem. Mater., 14 (9), 3643 -3650, 2002.

14

“Programmed” Self-

Assembly

How do we get to these

levels of complexity?