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WELCOME CENTRAL LEPROSY TEACHING AND

RESEARCH INSTITUTE, TIRUMANI,CHENGALPATTU

HISTORY

1924 Lady Wellington Leprosy Sanatorium at Tirumani

1924 to 1939

Managed by Church of Scotland. Dr. Paul Brand devoted his life for the reconstructive Surgery

1946 Before Independence, Mahatma Gandhi Father of our Nation visited the land of Tirumani. He gave written message of blessing to the patients of the Sanatorium and wished well to the staff.

SIGNATURE AND GREETINGS OF MAHATMA GANDHIJI

Significance of 30th January on 30.01.1946 – Father of the Nation visited CLTRI

Coincidentally, he died on 30.01.1948.

30th January every year celebrated as Anti Leprosy Day.

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HISTORY

05-01-1955 CLTRI was established by Government of India under a Governing Body

1957- 1966

Dr. Dharmendra famous Leprologist was associated with CLTRI as Director from 1967 to 1971 he was Emeritus Medical Scientist of CLTRI.

Significant Contribution :- Lepromin Test Standardization of DDS (Diamino Diphenyl Sulphone) a drug used for treating leprosy patients.

1967- 1971

1974 CLTRI became a subordinate office of DGHS under MOH&FW

1978-1983 Standardization of MDT (Multi Drug Therapy ) done in this Institute.

1991 Nodal Centre for Thalidoamide drug therapy for ENL (Erythrosom Nodosum Leprosom) reaction Cases.

OBJECTIVE To undertake research into basic problems relating to the occurrence and spread of leprosy and its control.

To train manpower necessary to implement NLEP.

To provide specialized services in the area of diagnosis, reaction, relapse and Reconstructive surgery in Leprosy.

To monitor and evaluate National Leprosy Eradication Programme.

Additional Responsibitiy given in 2005 after Elimination of

LeprosyCBHI TrainingRNTCP Operational ResearchIDSP Training

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AREA OF CLTRI

Total Land of CLTRI - 560.83 Acres

Institutional Buildings - 66.53 Acres

Residential Buildings - 28.72 Acres

Vacant Land - 190.58 Acres

Land Given to HLL (for proposed Mediparkon 20-03-2009 by MOHFW) - 275 Acres

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BUILDING1.HOSPITAL BLOCK :

Out Patient Unit Main Hospital -124 Bedded Hospital

Sick Room Medical Investigation Ward Surgical Ward with X-ray department & Operation

theatre

Physiotherapy Block MCR and Footwear Unit Centralised Kitchen Laundry Centralised Stores

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2. ADMINISTRATIVE BLOCK

a. Administration

b. Laboratory & Animal House

c. Library

d. Epidemiology

3. HOSTEL

e. Scientist Hostel - 18 Rooms

f. Students Hostel - 18 Rooms

g. Canteen

BUILDING (Continued)

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STAFF STRENGTH – STATUS REPORTSl. No. Group Total

Strength Filled Vacancy Vacancy Percentage

1 A ( Medical) Specialist

15 3 12 87%

GDMO 11 6 5 45%

2 A- Non Medical

3 0 3100%

3 B- Gazetted

5 2 360%

4 B- Non-Gazetted

19 14 526%

5 Group C 117 84 33 28%

6 MTS 80 56 24 30%

TOTAL 250 165 85 34%

66 % 34 %

Budget Estimate 2012-13S.No. HEAD PLAN NON-PLAN

10% reduction in Non-plan*

Balance Budget

1 Salaries 0 84150 0 84150

2 Wages 0 1400 0 1400

3 Overtime allowance 0 10 1 9

4 Medical Treatment 0 750 75 675

5 Domestic Travel Expenses 500 300 30 270

6 Office Expenses 2200 2020 202 1818

7 Publication 0 10 1 9

8Other Administrative Expenses 250 0 0 0

9 Supplies and Materials 3500 2800 280 2520

10 Minor Works 1550 0 0 0

11 Scholarships /Stipend 0 300 30 270

12 Other charges 0 10 1 9

13 Motor Vehicles 0 450 45 405

14 Machinery and Equipment 1500 300 30 270

  TOTAL 9500 92500 695 91805

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CLTRI

Clinical

Surgical Epidemiology & Statistics

Laboratory

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CLINICAL

Out Patient Department

Wards

Nursing Section

Medical Record Section

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• Expert Management of reactions with

Thalidomide, Relapses/Drug Resistance etc.

• Teaching activities in leprosy to

Undergraduates, House Surgeons of Medical

Colleges, NMS Supervisors and Nurses.

• Collection and study of relapse/recurrence

cases in leprosy.

CLINICAL (Cont.)

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CLINICAL (Cont.)

On Going research activity

Drug Resistance Surveillance using Mouse foot Pad

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Out-Patients particulars for the Last 5 years

2008-09 2009-10 2010-11 2011-12

2012-13(Till Oct )

1 No. of newCases

attended OPD

64 104 74 90 48

2 No. of oldCases

attendedOPD

7155 7220 6192 6094 3353

3 No. of patientsattended OPDfrom GLC block

2680 2074 1514 1694 776

4 No. of otherCases (NCL)Attended OPD

2224 1748 1441 1161 775

5 Total no. ofpatients seenin OPD

12123 11146 9221 9039 4952

GLC - Government Leprosy CentreNCL - Not a Case of Leprosy

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SURGICAL

Surgical Unit

Physiotherapy Section

Artificial Limbs & Footwear Section

X-ray Section

Micro-cellular Rubber

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Surgical (cont.)

The Basic functions:

• Reconstructive Surgery

• Patient care activities.

• Teaching and Training Programs.

• Research.

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Physiotherapy SectionPhysiotherapy Services to PAL.

Various Teaching and Training programs.

Counselling & Health Education.

Facilities Available Wax Bath, Electrical Muscle Stimulator, Inter Ferential Therapy, Ultra Sonic Therapy Traction Table.

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Artificial Limbs & Footwear Section

Footwear and Prosthetic to the Leprosy patients

Micro-cellular Rubber

Small Production unit - Micro-Cellular Rubber sheets (2000 sheets per annum)

Providing MCR sheets to other states

Details of Major and Minor Surgery Done for the Last 5 years

S.No

Surgeries 2007-08 2008-09 2009-10 2010-11 2011-12

Major Surgeries –(Reconstructive Surgery)1. Claw finger correction 7 7 14 6 8

2. Claw thumb correction 3 5 5 5 1

3. Wrist drop Correction - - 1 1 -

4. Drop Foot Correction 5 1 - 6 -

5. Lagapthalmos Correction - 1 2 - -

6.Surgical Decomposition ofNerves (Ulnar Nerve, MedianNerve, Posterior Nerve)

4 1 2 3 -

7.Amputation (Below Knee &Below Elbow Amputation) 4 2 - - -

Minor Surgeries8. Ulcer Surgery 53 16 20 5 -

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Miscellaneous like Biopsy, MTHResection, Calcaneal shaving,lagopthalmus, Skin Grafting,Cystectomy etc.

18 4 6 6 -

Physiotherapy Activities for the last 5 year

S.No

Activities 2007-08 2008-09 2009-10 2010-11 2011-12

1. New Case 70 55 77 51 195

2. Assessments

973 895 708 530 789

3. Hand Exercises

1905 1823 1742 1755 1943

4. Foot Exercises

857 797 737 714 749

5. Wax Therapy

1845 1741 1698 1598 1740

6. Splints 460 416 778 309 407

7. General Cases

91 60 67 52 71

Footwear and Prosthetic Supplied for the last 5 year

S.No

2007-08 2008-09 2009-10

2010-11

2011-12

1.

Simple andModified Microcellar RubberSandals (in pairs)

1234 1119 1199 942 500

2.

Orthotic andProsthetic Appliances(in

no’s)

23 21 25 28 5

3.

Major repair ofOrthosis andProsthesis (in

no’s)

8 4 13 12 1

4.

Modifications Arch

Support andMetatarsal Bars (in no’s)

144 115 171 93 54

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Division of Epidemiology& Statistics

Monitoring &

Evaluation Unit

Statistics

Electronic Data

Processing Unit

Technical Training Library

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Division of Epidemiology & Statistics

CLTRI Website was created by our unit.

Website for our institute was hosted in NIC server (http://cltri.gov.in/).

Logo for our Institute was designed.

Inventory Management Software was developed.

Consultancy services to the BCGVL, Guindy, Chennai for creation of website and Inventory management system.

Monitoring & Evaluation of NLEP Activities among

Tamil Nadu, Karnataka, Kerala and Lakshawdeepstates/UT was carried out.

Visits Made for Monitoring Activities Lakshadweep Islands - 2000 population of

school children were Examined on January 2012.

Tamil Nadu, Karnataka, Pondicherry States/UT

for planning M & E Activities.

M & E conducted in Erode District, Tamil Nadu.

Monitoring & Evaluation of NLEP Activities

Phase I of the Activity Study of the Household and

Neighbourhood Contacts of newly Reported

Leprosy cases in the CLTRI OPD from

Thirukalukundram Taluk area work was carried

out during October 2011.

Phase II of the Activity is started on August 2012and completed on September 2012

Analysis of the collected data is under process.

Surveillance Activities

SFC proposal for Strengthening of CLTRI was

Prepared and submitted in DGHS (17 Oct 2012).

Operational Research Study to ascertain the

reasons for High Endemicity in 24 districts of 3

states (Andhra Pradesh, Gujarat, Karnataka)

was send to CLD(31 May 2012).

PROPOSALS

OPD Data -New case attending CLTRI OPD for the

past 2 year were entered and analysed.

Spatial Distribution of (Geographical Information) of New cases attending CLTRI was prepared.

Monthly progressive Report from districts of Tamil Nadu, Andhra Pradesh and other states were received and entered into Computerised Simplified Information System (CSIS).

Analysis of Reaction Case data is under process.

Data Analysis

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Training Activities • State/District Leprosy Officer (SLO/DLO) = 3 batches

(5 days)

• Medical Officer Training Course (5 days) = 2 batches

• Non-Medical Health Supervisor’s (2 months) = 2 batches

• Skin smear Technician Training (5 days) = 1 batch

• Laboratory orientation Training (BCG Staff) = 2 batches

• Final MBBS students (one day visit) =125 students

• CRRI Training (5 days ) =110 Trainees

• Tertiary case management of Leprosy (10 days) = 1 batch

• Inplant training in Microbiology & = 1 batchMolecular Biology to Biotechnology students

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Library

• Books - 3278

• Journal - 4409

• Periodicals

Foreign journals - 24

Indian Journals - 09

• Dr. V.C.Giri Assistant Director (Epid) attended HIVCONGRESS 2012, Held at Mumbai from 16th to 18th March 2012, Presented one Research paper and Two paper by Co-authors in scientific session.

Attended RTI Act for Public Information Officer training at ISTM, New Delhi –August 2012

Published 2 paper in International Journals.

• Dr. V.C.Giri, AD (Epid) & Dr. R. Veerkumaran, CMO delivered lectures in Leprosy CMC organised by Tirunelveli Medical College, Tirunelveli, Tamil Nadu.

• Mr. U. Aravindan, Statistical Investigator Gr. II attended training in Statistical Analysis system (SAS) training held at Christian Medical College, Vellore, Tamil Nadu.

Workshop/Conference / Training Attended

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Biochemistry & Animal Hou

se

Sterilisation

Hematology & ImmunologyMicrobiology &

Molecular Biology

Clinical Pathology & Histopathology

LABORATORY

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LABORATORY (cont.)

Investigation for Leprosy related and other Routine Investigations

Basic and Applied Research activities in Leprosy.

Research in field of Diagnosis, Molecular Biology, Drug therapy, Animal studies in the field of Leprosy etc.,

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LABORATORY (cont.)

On going Research projects:

Study on surveillance of Drugs [rifampicin

and dapsone] resistance, among smear

positive multibacillary leprosy cases

Detection of fumonisin producing Fusarium

species from rice seeds by polymerase chain

reaction.

Variable number tandem repeats VNTRs

finger printing as an Epidemiological marker

for Mycobacterium leprae haplotyping

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Laboratory Investigations in the Last 5 years

S.No

DEPARTMENTS / SECTIONS

2008-09

2009-10

2010-11

2011-12

2012-13

1 Clinical Pathology & SkinSmear

1233 1010 831 1168 669

2 Hematology & Serology 2255 3316 3000 3767 1980

3 Microbiology 262 397 100 129 82

4 Histopathology &Molecular biology

(Routine &Research activities)

483 4 71 331

5 Biochemistry 1705 1705 3130 3244 1463

6 Animal Position in theAnimal House1. Balb/C Mice Inbred

Strain 2. Swiss Albino Mice

Inbred Strain3. Rabbit … …

4. Rat … …

5.Sheep

323269

614

323269

614

548496

4

548496

4

548496

4

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Scientific Publications in last 1 year

Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy. Lepr Rev. 2011 Mar;82(1):36-45.

OXA beta-lactamase-mediated carbapenem resistance in Acinetobacter baumannii. Indian Journal of Medical Microbiology, Vol. 29, No. 3, July-September, 2011, pp. 269-274

Detection of Amp C genes encoding for beta-lactamases in Escherichia coli and Klebsiella pneumoniae. Indian Journal of Medical Microbiology, Vol. 30, Issue 3, 2012, pp. 290-295

blaIMP AND blaVIM Mediated Carbapenem Resistance in Pseudomonas and Acinetobacter species in a Tertiary Care Hospital in India. The Journal of Infection in Developing Countries, October 2012.

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SIGNATURE AND GREETINGS OF MAHATMA GANDHIJI

Phase I:9 cluster are surveyed out of 18 clusters2531 population was Examined 13 Cases case were found. NCDR= 51.36 per 10000

Phase II:9 cluster are surveyed out of 18 clusters3702 population was Examined 13 Cases case were found. NCDR= 35.11 per 10000

  Adult Child Total

Paucibacillary (PB) 6 3 9

Multibacillary (MB) 4 0 4

Adult Child Total

Paucibacillary (PB) 6 3 11

Multibacillary (MB) 2 0 2