SAFE HARBOR SUMMARY

This presentation includes forward‐looking statements that are subject to many risksand uncertainties. These forward‐looking statements, such as our statements about ourshort‐term and long‐term growth strategies, can sometimes be identified by our use ofshort term and long term growth strategies, can sometimes be identified by our use ofterms such as "intend," "expect," "plan," "estimate," "future," "strive" and similarwords. Although we believe that the expectations reflected in our forward‐lookingstatements are reasonable, those statements involve many risks and uncertainties thatmay cause our actual results to differ from what may be expressed or implied in ourstatements. Those risks are discussed in our registration statement on Form S‐1, whichis on file with the Securities and Exchange Commission, particularly in the sectionstitled "Risk Factors" and "Management's Discussion and Analysis of Financial Conditionand Results of Operations." No forward‐looking statement is a guarantee of futureresults, and you should not place undue reliance on our forward‐looking statements,which reflect our views as of the date of this presentation We assume no obligation towhich reflect our views as of the date of this presentation. We assume no obligation toupdate any forward‐looking statement contained in this presentation, except as may berequired by law.

2

WE MAKE OIL

WE CONVERT LOW COST PLANT SUGARS TO HIGH VALUE RENEWABLE OILS – FOR FUEL, FOR FOOD, FOR LIFE

3

WE MAKE OIL

Limited Suitable Land for Oil Global Petroleum Demand (B barrels / year)

17%

Source: EIA

83% Carbohydrate

17% Oil

Source: FAO

Natural Oils Market Growing (M MT / year)  

Carbohydrate Source: FAO

Source: FAO

4

PETROLEUM PLANT OILS ANIMAL FATS

THE THREE SOURCES OF OIL TOUCH OUR LIVES DAILY

Jet Fuel

PETROLEUM$2.9 T Market

PLANT OILS$206 B Market

ANIMAL FATS$29 B Market

Paint

Jet Fuel

Dielectric Fluids

Clothing

Computer

Cosmetics

Medicine

Paint

Mattress

Detergent

LotionShampoo

Soap

Floor Tiles

CookiesButter

Cooking Oil

Ceiling Tiles

Lacquer

CandlesLubricants

Tires

Mayo

Cleaner

TV Frame

Spraypaint

Hose

Upholstery

Diesel

Boots

Pet FoodIce Cream

Adhesive

TV Frame

Engine Grease

Car Seating

Fertilizer

5

SOLAZYME – A NEW SOURCE OF OIL

Jet Fuel

PETROLEUM PLANT OILS ANIMAL FATS SOLAZYME

Dielectric Fluids

Paint

Jet Fuel

Floor Tiles

Cosmetics

Medicine

Paint

Mattress

Detergent

LotionComputer

Shampoo

SoapClothing

Upholstery

Ceiling Tiles

TV Frame

HoseButter

Cooking Oil

Lacquer

CandlesLubricants

TiresCookies

Mayo

CleanerSpraypaint

Adhesive

TV Frame

Engine Grease

Car Seating

Diesel

Boots

Pet FoodIce Cream

Fertilizer

6

OUR TARGET MARKETS

FUELSFUELS CHEMICALSCHEMICALS NUTRITIONALSNUTRITIONALS SKIN & PERSONAL CARESKIN & PERSONAL CARE

TAM = > $800 B TAM = > $100 B TAM = > $50 BTAM = > $600 B

Target Markets > $1.5 trillion

7

g $

BREAKTHROUGH BIOTECHNOLOGY PLATFORM

FLEXIBLE INPUTFLEXIBLE INPUT MULTIPLE HIGHMULTIPLE HIGH‐‐VALUE MARKETSVALUE MARKETSFUELSFUELS

Corn and StoverCorn and StoverCorn and StoverCorn and Stover

SugarcaneSugarcaneSugarcaneSugarcane

CHEMICALSCHEMICALS

NUTRITIONALSNUTRITIONALSSwitchgrassSwitchgrassSwitchgrassSwitchgrass

MiscanthusMiscanthusMiscanthusMiscanthus

Waste StreamsWaste StreamsWaste StreamsWaste Streams

Forest ResidueForest ResidueForest ResidueForest Residue

SKIN & PERSONAL CARESKIN & PERSONAL CARE

HIGHLY PRODUCTIVE MICROALGAEHIGHLY PRODUCTIVE MICROALGAE OIL DESIGNED TO SPECIFICATIONOIL DESIGNED TO SPECIFICATION

> 80% oil**The average wild algae only has a 5‐10% oil content

8

TAILORING OILS TO ENHANCE VALUE AND MEET CUSTOMER NEEDS

CHAIN LENGTH CONTROL Chain Length Engineering(C10 – C14)

Saturation Engineering

SATURATION LEVELt o

f Total

Percen

t

FUNCTIONAL GROUPS

9

PROVEN TECHNOLOGY ENABLES SIGNIFICANT MARGIN OPPORTUNITIES

TargetTarget Gross

Margins

60‐80%  40‐70% 30‐60%        30‐60%

$2,500 – $20,000 / MT

$20,000 – $4 M / MT

$1,000 – $2,300 / MT

$1,800 – $5,000 / MT

Legend:

<$1,000 / MT (1)

FUELSFUELS

<$1,000 / MT

CHEMICALSCHEMICALS

$1,000 – $2,000 / MT

NUTRITIONALSNUTRITIONALS

$1,000 – ~$1 M /MT (2)

SKIN & PERSONAL CARESKIN & PERSONAL CARE

10

Average Selling PriceCost of Production(1) Production cost over time based on built‐for‐ purpose commercial manufacturing facility utilizing sugarcane feedstock(2) The ~$1 million / MT production cost and $4 million / MT ASP is for Alguronic Acid® 

LOW COST PRODUCTION PROVEN AT SCALE

Lab5‐15 liter

S S F i

Commercial*128,000 liter

S San Francisco

Pilot Plant600‐1,000 literS San Francisco Commercial

75,000 literPennsylvania and CaliforniaIn operation since 2007

Demonstration20,000 liter

11

128,000 literPeoria, Illinois

*Acquired May 2011

DEMONSTRATION AND COMMERCIAL FACILITY TODAY

Solazyme PeoriaSolazyme PeoriaSite acquisition March 2011

12

VALUE CHAIN

DOWNSTREAM, DISTRIBUTIONDOWNSTREAM, DISTRIBUTIONMANUFACTURINGMANUFACTURINGUPSTREAMUPSTREAM

FERMENTATIONFERMENTATION BRANDING CONSUMPTIONBRANDING CONSUMPTIONFEEDSTOCKFEEDSTOCK

FUELS & CHEMICALSFUELS & CHEMICALS

FERMENTATIONFERMENTATION BRANDING, CONSUMPTIONBRANDING, CONSUMPTIONFEEDSTOCKFEEDSTOCK

FUELS

NUTRITIONALSNUTRITIONALS

CHEMICALS...and others

SKIN AND PERSONAL CARESKIN AND PERSONAL CARE

Commodity‐Based Contracts

13

COMPELLING SITE SPECIFIC VALUE PROPOSITION

Multiple Tailored Oils(~100K MT of oil)

T t ASP

One Modular Facility(Capex ~$90‐110 M)

FUELS & CHEMICALSFUELS & CHEMICALSOne Feed Stream(~300K MT of sugars)

Target ASPs$1k–5k/MT

SugarcaneSugarcaneSugarcaneSugarcane

Target ASPs$2.5k‐20k/MTPartner‐Owned Mill

Corn and StoverCorn and StoverCorn and StoverCorn and Stover NUTRITIONALSNUTRITIONALS

Low switching costsSKIN & PERSONAL CARESKIN & PERSONAL CARE

Target ASPs$20k‐4m/MT

14

SOLAZYME ROQUETTE NUTRITIONALS

Feedstock supply

Technology Know‐how

Feedstock supply Working capital Global distribution 100% capex for commercial plant (>50k MT)

/50/50 JOINT VENTURE

15

BUNGE SOLAZYME JV FRAMEWORK AGREEMENT

Key PointsKey Points

• 100,000 MT (30M gallons) renewable oil production facility 

• Located at a Bunge sugar cane mill in Brazil 

• Equity funded by both parties

• Value sharing mechanism provides SZYM compensation for    technology contributions

• Commercial engineering and permitting begins immediately

• Ground breaking in first half of 2012

• Plant start‐up projected for 2013 cane harvest

16

FUELS COMMERCIALIZATION FUELSFUELS

TAM = > $800 B

Shipping large quantities thatmeet fuel standardsShipping large quantities… …that meet fuel standards…

CURRENT FUELS PARTNERSCURRENT FUELS PARTNERS

17

FUELS – ALREADY TESTED

Solazyme’s 100% algal‐derived hydrotreated renewable jet fuel (HRJ‐5)

Solazyme’s 100% algal‐derived hydrotreated renewable diesel  (HRF‐76)(HRJ‐5) (HRF‐76)

18

BARREL OF OIL

Average Value: $200‐600/barrelAverage Value: $200‐600/barrel

SOLAZYME OIL

Average Value: $90‐110/barrelAverage Value: $90‐110/barrel

PETROLEUM

>80% = 

Plasticizers

Lubricants

Jet

VALU

EVA

LUE Tailored Oil

Diesel

Diesel Sweetener

Gasoline

Heating Oil

Tar

Asphalt

19

CHEMICALS COMMERCIALIZATION CHEMICALSCHEMICALS

TAM = > $600 B

SOAPS, SURFACTANTS AND DETERGENTS

EXAMPLE OILSEXAMPLE OILS MARKETSMARKETS PARTNERSPARTNERS

Oil Size ASP ($/MT)

Linseed* $  2 B $3,100

PAINTS, COATINGS AND PLASTICIZERS

Palm Kernel $11 B $1,765

Coconut $  7 B $1,803

S fl $18 B $1 700

FUNCTIONAL FLUIDS DIELECTRICS

Sunflower $18 B $1,700

SOLAZYME’S VALUE PROPOSITIONI d i ld FUNCTIONAL FLUIDS – DIELECTRICS, 

LUBRICANTS, AND HYDRAULICS Increased yield

Improved product performance

Improved stability

20 * Advanced drying oil

TAILORED OILS VALUE PROPOSITION: PKO CHEMICALSCHEMICALS

TAM = > $600 B

Tailored Oil Case Study: Palm Kernel Oil

PKO is used in soaps, detergents and food

Palm Kernel Oil Solazyme’s Oil (PKO+)

Low Value Solazyme’s technology can produce oils with 25‐50% more desired fatty acids

Solazyme’sTailored Oil Technology

Low ValueFatty Acids

Market Size of $11 B

Low ValueFatty Acids

Technology

55%High ValueFatty Acids

(Lauric & Myristic))

80%High ValueFatty Acids

(Lauric & Myristic)

Price PKO = $1,765/MT Est. Price PKO+ = $2,382/MT

21

NUTRITIONALS COMMERCIALIZATION NUTRITIONALSNUTRITIONALS

TAM = > $100 B

Native and refined algal oils

Composition of first product similar to olive oil

Natural algal flours and powdersg f p

Can replace eggs, butter and oil

Golden Chlorella

i h i d hi h il i l

Tailored nutritional oils

Designer oils for improved functionality

High protein and high oil nutraceuticals

FUNCTIONAL AND HEALTH  BENEFITS

No trans fatf

Longer shelf lifef l h

esigner oils for improved functionality

22

Lower saturated fat Specific melting characteristics

SKIN & PERSONAL CARE COMMERCIALIZATION SKIN & SKIN & PERSONAL CAREPERSONAL CARE

TAM = > $50 B

Highlights

$3.6 million in sales in less than four months

ALGURONIC ACID®

U.S. & European DistributionSold in 850 Sephora storesSpring & Summer launches SOLD OUT  on QVC

CanadaSold in all 26 Sephora Canada storesJuly 5th launch on The Shopping Channel 

U i d Ki dUnited KingdomSold in 60+ Space NK storesJuly 28th launch

23

1H 2011 FINANCIAL HIGHLIGHTS

Revenue $15 1MRevenue

Product revenue

Research and Development programs

$15.1M

$3.6M

$11.5M

Non‐GAAP Operating Expenses

Non‐GAAP Net Loss

($24.3M)

($15.6M)

Capital Expenditures

Ending Cash and Investments

($10.1M)

$266M

24

MANUFACTURING PLAN TO SUPPORT >$1 BILLION IN REVENUE

Solazyme Peoria and contract manufacturing meet near‐term needs

Plan to >550,000 metric tons of tailored oil capacity

C t bi di fft k d l d 2015 it Current non‐binding offtakes exceed planned 2015 capacity

2013 Fuels & Chemicals facility estimated cost $90‐110 million

NUTRITIONALSNUTRITIONALSFUELS & CHEMICALSFUELS & CHEMICALS

500,000Phase 3

300,000

,

55,300 55,300

Phase 1Phase 2

1,300 2,600

100,0005,300 10,300

25

(in Metric Tons)

COMPLETED

BUILDING VALUE

• Commenced retrofit of Peoria facility

E d d Al i

20132H 2011COMPLETED

• Integrated DOE biorefinery online

B k d 100K MT f ili

• Commence production at Peoria

Al i ™ li i

• 100K MT facility for Fuels and Chemicals completed

B k d Ph III

2012

• Expanded Algenist distribution channels

• Produced over 283K liters of in‐spec fuel for U.S. Navy

• Break ground 100K MT facility

• Phase II facility for SRN

• Second skin care line

Produce additional 283K liters

• Algenist™ line extensions

• Phase I facility for SRN

• Rapid prototyping of  new tailored oils

• Break ground on Phase III facility for SRN

• Break ground on additional capacity for tailored oilsNavy

• Secured Phase II DoD funding for additional 283K liters of in‐spec fuel 

• Produce additional 283K liters of in‐spec fuel for U.S. Navy

• Rapid prototyping of  new tailored oils

• Brazil R&D lab operational

• Additional feedstock/mfg partnership

tailored oils

• Rapid prototyping of  new tailored oils

• Additional feedstock/mfg • Expanded 

commercialization management team

• Initiated additional fuel demonstration

• Binding offtakes

• Algalin Flour product launch for SRN

• Additional feedstock/mfg 

• Expansion of downstream partnerships

partnerships

• Expansion of downstream partnerships

• Positive EBITDA by FYEdemonstration / g

partnerships

• Expansion of downstream partnerships

• Positive EBITDA for Skin and

26

• Positive EBITDA for Skin and Personal Care by FYE

INVESTMENT HIGHLIGHTS

Large Market Opportunity

PETROLEUM$2.9 T Market

Products on Shelves Today

PLANT OILS$206 B Market

ANIMAL FATS$29 B Market

27

THANK YOU

28