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11–15 Farm Street, London W1J 5RG www.hooke.london © HOOKE 2021. Health and Longevity Optimisation Ltd. t/a HOOKE Company No. 11928940
Transcript

11–15 Farm Street, London W1J 5RG www.hooke.london

© HOOKE 2021. Health and Longevity Optimisation Ltd. t/a HOOKE Company No. 11928940

2HOOKE

Expanding expectations of human life

3 HOOKE is an elite lifestyle medicine programme and longevity research centre. Our vision is to help you achieve and exceed your human potential, so you can enjoy a healthy and happy life long into the future.

THE VISION

4 We design and deliver complete, sustainable health solutions that are built around your unique needs and goals. Our team of doctors, scientists and specialists use the latest in diagnostic testing technology to perfectly align your medical treatments, diet, exercise, medications and mindset.

Our team-based approach is modelled on the clinical panels who treat, train and advise elite professional athletes. Individual specialists work together, joining the dots between their fields to create a head-to-toe plan that supports you as the whole person, rather than a kit-of-parts.

We strive to manage our members’ health in the same way the best family offices manage their wealth: proactively, analytically and by offering the best products and services available globally. Just as wealth managers aim to maximise their clients’ wealth, the team at HOOKE works to maximise our members’ health, helping them to be at their best both now, and into their 80s and 90s.

THE OFFER

THE APPROACH

IN OTHER WORDS

5 Our approach is underpinned by intensive diagnostic screenings that take place three times per year. Our process includes blood analysis, genetic testing, physical and mental health consultations, musculoskeletal fitness and nutritional assessments. We understand that taking time out of your busy schedule can be a challenge, but regular screenings enable us to keep pace with your needs and deliver lasting results.

We provide ongoing support, advice and encouragement, to ensure that you continue to feel the benefits of our work for years to come. This means cultivating a long-term relationship and continually adjus-ting your health plan over time, as your circumstances and life stages change.

HOOKE London’s programme development is led by Dr ERIC VERDIN of the Buck Institute for Research on Aging – a leading global authority on longevity science. You will be one of the few private patients in the world to benefit directly from Dr Verdin’s expertise and the best of the Buck Institute’s advanced ageing science. By being part of this programme, you can be sure that you are not only improving your life, but also helping to advance this exciting field of medicine for the benefit of all.

THE JOURNEY

THE BIGGER PICTURE

THE COMMITMENT

6

Lev MikheevFROM OUR FOUNDER The HOOKE London

story began in 2012 when my wife gave me a book by Professor HENRY S. LODGE of Columbia Medical School entitled “Younger Next Year”. The premise of the book is that most people move less as they age – becom-ing progressively more sick long before they die. However, those who reverse that declining movement pattern and exercise five days a week, can maintain their fitness level from their early forties into their early eighties.

At the time, I was a successful but burnt out, hedge fund manager, and I took this advice as stereotypical American hyperbole. However, I like challenges and decided to try Professor Lodge’s programme for a couple of months. Today, I am 57, and not only do I run and cross-country ski faster than I did in my twenties, but I also continue to improve my personal best times. At least in this respect, I am getting younger every year!

The hidden potential that I have discovered in myself goes well beyond endurance sports. In his recent book, “The Changing Mind”, the prom-inent neuroscientist DANIEL LEVITIN lists many examples of scientists and musicians in their late eighties and early nineties who are still at the top of their fields; indeed my own father marked his

90th birthday with a highly successful solo cello recital at the Moscow Conservatory. Surveys also demonstrate that people surviving into their early eighties report the highest satisfaction with life of all the age cohorts above 20. It turns out there is a benefit to age – it is called wisdom!

I am convinced that these examples of successful ageing are not an exception, and that they can be the rule. Any middle-aged person willing to apply a concentrated effort to their physical and cognitive fitness can look forward to having the best years of their lives ahead of them.

HOOKE London was born from my own experiences and a desire to share the information, inter-pretations and interventions needed to make your later years the happiest, healthiest and most productive of your life. We are all infinitely more capable and more complex than we appear – together we can unlock this opportunity and create an important proof of concept for how health services should be delivered in the 21st century. I hope that all HOOKE London members will share my sense of excitement and responsibility on our journey together.

“Make your later years the happiest, healthiest and most productive of your life.”

7 Dear Friend, I am delighted to welcome you to HOOKE. While your primary intent may be to enhance your health, you are joining us on a voyage much larger than better health – a truly exciting adventure of self-discovery and optimisation. Some might choose to travel and explore exotic countries, yet I expect that your journey with HOOKE will transform the way you live, change your expect-ations of how you will age and ultimately enhance the quality of your life beyond what you ever thought possible.

I started my own journey in health close to 40 years ago. Trained in medical school, I soon learned that traditional medicine focuses primarily on diseases. One is considered healthy until a catastrophic event strikes, maybe a heart attack, a newly diagnosed cancer, or a hip fracture. By then, damages that have accumulated over decades are oft- en irreversible. The majority of people reaching 65 today are afflicted by at least one of the chronic diseases of aging, such as heart disease, stroke, type 2 di-abetes, and cancer. As the risk of these diseases rises exponentially as we age, most of us face the last decades of our lives unable to live to our full potential.

It does not have to be this way. Our understanding of aging has undergone a revolution in the last thirty

years. During this period, we have learned that aging is a highly malleable process that can be controlled. We have identified drugs and lifestyle interventions that slow down the rate of aging and we have developed novel markers to measure biological age, which is not always the same as chronological age. We have also learned that more than 90% of your lifespan and healthspan (healthy years of life) is determined by your lifestyle and only 7% by your genes, thereby offering a true possibility of lifestyle intervention for maximising healthspan. We now know that interventions that increase lifespan have the surprising side effect of suppressing the development of the chronic diseases of aging, and increasing healthspan. These findings have the potential to shift the focus of modern medicine from the treatment of disease to the maintenance of health.

The healthcare industry will advance rapidly in the next few years with the introduction of digital technology and telemedicine. HOOKE will combine these developments in technology with cutting edge research in aging and live expert intelligence, and translate them for the benefits of our members.

Dr Eric VerdinFROM OUR CHIEF SCIENTIFIC ADVISOR

“HOOKE will combine these developments in technology with cutting edge research in aging and live expert intelligence, and translate them for the benefits of our members.”

24

Member pathway

HOOKE

25 Membership with HOOKE is an investment of your time and focus. You will meet with your multidisciplinary team for screening three times a year. They will produce an in-depth report for you to follow, and offer interim support between testing cycles.

This approach means that your plan will always be based on up-to-date scientific evidence and be inline with your goals.

PATHWAY

6 MONTHS

Assessment— Medical— Cognitive— Nutrition — Fitness

MDT meeting

Report

CONTINUOUS

Our cycle of assessments and programmes continues every 6 months

3 MONTHS

Interim testingInterim report

0 MONTHS

Initial Assessment— Medical— Cognitive— Nutrition — Fitness

Multidisciplinary team meeting

Report

START PROGRAMME 1

MONTHLY TOUCHPOINTS

MONTHLY TOUCHPOINT

MONTHLY TOUCHPOINTS

START PROGRAMME 2

REPEAT CYCLE

27SUMMARY OF SERVICES Two times a year — Medical assessment with

principal physician— Musculoskeletal and Fitness

assessments with MSK and fitness specialists

— Nutrition assessment with cardiometabolic specialist

— Cognitive function and performance with performance coach and/or psychotherapist

— Blood analysis— Report of findings, analysis

and recommendations— Follow up appointments

with each of our specialists

Ongoing support — By email, phone or video conferencing

— Minimum monthly touch-points — Interim letter report

Annually — Full body and brain MRI scan

OptionalFurther medical and specialist services upon referral

Membership includes— OGD (gastroscopy) and

colonoscopy— CT (cardiac computed tomography)

calcium scoring— Full genotype analysis and

polygenic risk score

Repeated based on findings and medical recommendation

Wearables (yours to keep)— Oura Ring — KardiaMobile 6L— Pulse Oximeter — MyZone belt— Omron Evolv BP — Dexcom continuous glucose monitor

Term Rolling one year term with two cycles of core services per year

8

Our team of experts

HOOKE

9 Our team of physicians, psychologists, nutritionists, personal trainers and scientists have all been carefully chosen for their unrivalled medical pedigree.

They pride themselves on a commitment to exceptional service, and to meeting the needs and preferences of the individual. And they work collaboratively to turn cutting-edge research into practical, evidence-based advice.

THE TEAM

10

PIERRE-MARC BOULOUX qualified in 1978 from St Bartholomew‘s Medical College and after post graduate training at the Hammersmith and Brompton Hospitals, trained in Cardiology in Brussels before obtaining an MRC Fellowship in Endocrinology in the Department of Endocrinology St Bartholomew’s Hospital under Professor MICHAEL BESSER. He obtained an MD in 1987 and was elected FRCP in 1993. He was appointed Senior Lecturer in Endocrinology at the Royal Free Hospital in 1991, and was awarded a personal Chair in 2004.

Professor Bouloux has published extensively in the areas of neuroendocrinology and reproductive medicine with over 200 peer reviewed papers and 204 chapters and reviews. He has been a visiting professor in the USA and carried out research at the Pasteur Institute in Paris.

Furthermore, he has supervised 14 PhD students and three MDs and served on several committees both at the Royal College of Physicians and Society for Endocrinology. Additionally, he has published four textbooks in the area of endocrinology and general medicine. He has an interest in the neuroendocrinology of exercise and brings extensive clinical experience to HOOKE London.

PRINCIPAL PHYSICIANTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

11

DAVE COLLINS became a psychologist and academic after careers in the military and as a teacher. In his main domain of performance, he has worked with over 80 world or Olympic medalists, professional teams and performers in sport, music, and dance. Dave currently holds the post of Professorial Fellow in Human Performance Science at Edinburgh University and is a Director of his own company, Grey Matters Performance Ltd.

In his career so far, Dave has published over 350 peer review papers and 70 books and chapters. His research interests include expertise and the promotion of peak performance for people at all levels.

More recently, Dave has expanded his interest and focus to human development across a broader range. His work has been used as the basis for personal development programmes in schools and colleges. At the other end, Dave has enthusiastically committed to the goals of HOOKE, bringing a multidisciplinary and psychophysiological performance focus to health and life quality promotion.

When not working at one of these challenging roles, Dave is a keen outdoor enthusiast, both on, in and under the water. With that and keeping up with his large family, Dave is kept in reasonable, if rather large, shape!

LEAD PERFORMANCE PSYCHOLOGISTTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

12

Dr DAVID PORTER is an internationally renowned senior football and sports medicine physician specialising in all aspects of orthobiologics. He qualified in 2004 from University College London Medical School. Following specialist training in emergency and intensive care medicine, he was appointed to Chelsea FC as the Club Doctor in 2011. At the beginning of the 2015/2016 season he was appointed to the role of Men’s First Team Doctor at Chelsea FC. Over the following four football seasons he worked with the team at the training ground and travelled with them domestically and internationally on tour and in competition.

During his tenure at Chelsea FC, Dr Porter studied Sports and Exercise Medicine at leading institutions both in the UK and Europe. He also served on the faculty of the ATMMIF course, facilitated by the FA, where he taught emergency protocols to fellow sports medicine physicians, club doctors and physiotherapists.

Working in elite performance-focused sport for the nearly a decade has given Dr Porter unrivalled access to the latest and safest treatment developments. He has researched and brought a pioneering stem cell therapy to the UK by working with national regulatory bodies to ensure patient safety and treatment success.

Following an exceptional career at the highest level in professional football, Dr Porter is now translating his elite sports medicine experience to a wider patient focus at HOOKE London.

SPORTS AND MUSCULOSKELETAL LEADTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

13

Dr DINA RADENKOVIC is an academic doctor and medical technology entrepreneur. She qualified with a dual degree in medicine and physiology from UCL Medical school. Her commitment to improving people’s lives has assumed many forms, and taken her around the world to some of the world’s most respected hospitals and universities.

She has worked at the Barts Heart Centre where she co-developed the first publicly available tool in cardiac MRI for fractal analysis. She spent a medical elective at the Massachusetts General Hospital and the New England Journal of Medicine. She was a Research Fellow at King’s College London and had a research post at Harvard University. Most recently, Dina worked on the frontline during the Covid-19 pandemic at St Thomas’ Hospital, London.

Dina’s innate ability to think outside the box has led her to achieve numerous prizes and accolades. She founded Be The Change UCL and won the National NHS Quality Improvement Championship in 2016. Her work on diets for health received the nomination for the Young Investigator Award of the European Society of Cardiology in 2020. She launched her first company, Watch Out Diabetes, which successfully implemented a digital gestational diabetes prevention programme and became part of the Founders Forum and the NHS Glucofocus Accelerator.

Dina is an amateur passionate long-distance runner and at times picks up her dancing shoes.

CHIEF SCIENCE OFFICERTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

14

MARK ROBERTS has worked within the fitness industry for over 25 years and is a fully qualified strength and conditioning coach and sports nutritionist. He is the Founder and Director of Personal Space Ltd, a personal training and therapy centre in the heart of London. Over the last 14 years he has led a team of experts and specialists, from clinical nutritionists to exercise and rehabilitation coaches. He was the speed, strength and conditioning coach for Harlequins RFU between 2005 and 2007. He was appointed the fitness expert for Sky Television and has made numerous media appearances.

His philosophy is that training is only one part of the equation. In managing and allowing clients to become more accountable to themselves, Mark can enable immediate results and, more importantly, provide long term change. He is able to provide well designed and balanced programmes to all of his clients, whatever their goals or entry level to health and fitness.

Mark has a life-long passion for health and fitness. An accomplished sportsman, he switched from rugby union to athletics as a hurdler and then went into multi event competing at National level in the Decathlon. He still competes internationally as a Masters athlete, in the Decathlon as UK champion, and has won medals at European and World level competitions.

LEAD STRENGTH AND CONDITIONING COACHTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

15

MARK BOYDEN trained at Columbia University and is a certified assessor in NBI and Hogan Psychometric testing. He gained extensive training in psychoanalytic therapy and Cognitive Analytic Therapy (CAT) at Guy’s Hospital. Mark has nearly 18 years of combined experience working in the health professions and psychotherapy and as an addictions specialist.

Before his training, Mark held senior management roles at several blue-chip organisations, giving him a deep, personal understanding into the challenges of leadership and business responsibility. Since 2014 Mark has been a Director of Lionheart Consulting, providing specialist coaching to family offices, companies, philanthropic foundations, universities and government.

Mark’s approach focuses on building a secure, collaborative relationship as a framework for the therapy through scrupulous attention to confidentiality and professional boundaries. He works at the member’s pace, attending to strengths and resources as well as areas of difficulty.

When not working with members remotely, Mark has been creating a dedicated yoga space in his home in Dorset – an imaginative response to his favourite gyms being on lockdown!

PSYCHOTHERAPIST AND EXECUTIVE COACHTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

16EXECUTIVE DIRECTOR

KATE WOOLHOUSE comes from a legal background, having qualified as an intellectual property solicitor and spent a decade at leading UK and US law firms. Kate advised a broad range of clients, ranging from listed companies to start ups, to sole traders, giving her an understanding and enthusiasm for taking commercial enterprises from inception, to launch and expansion.

While practising as a lawyer, Kate focussed on intellectual property, regulatory and corporate/commercial matters in industries including digital/IT, retail, medical devices and biotech. A significant portion of her practice was dedicated to navigating the perils and pitfalls of privacy and data protection.

Kate joined HOOKE because she loves working with innovators and disruptors to realise a vision. She advised HOOKE from the point of incorpo-ration and took up a non-exec role with the company in September 2019, before becoming Executive Director in January 2020. She now manages the financial, commercial and regulatory aspects of the business.

Outside of work, Kate is a trustee of a family charity that supports education and the arts. She is a keen cook and in her spare time endeavours to work off the calories in spin class.

THE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

17

ALEXIS KEMP has a first degree in English and a Postgraduate in Fashion and Lifestyle journalism. Alexis quickly realised that her skills lay in dealing with people and not prose, so she became a publicist at the leading communications agency, Public Eye. There, Alexis looked after some of the most high profile talent worldwide, and developed her expertise in excellent communication and people management skills.

With a clear passion and impeccable track record for client service, Alexis moved from the media world to that of the UHNW and spent the next twelve years working for Concierge London (now Somerset White) in both the UK and US. During her tenure, Alexis successfully balanced the unique demands of working in elite client management alongside developing a growing business. She guided the company’s PR coverage, sourced and trained all company staff worldwide, and built partnerships with top banks, private offices, funds and trusts. Her efforts grew the business across both London and New York and established Concierge as a leader in its field with an exceptionally trained team.

It is her acute business acumen and honed people management skills that Alexis brings to the HOOKE London team along with a passion for exercise, nutrition and wellness. She is a firm believer in taking a holistic approach to all facets of health and wellbeing, starting from the inside out, and enjoys exploring new avenues for such when time allows.

SERVICE DIRECTORTHE TEAM

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

18

LEV MIKHEEV is a Russian-educated polymath. His curious mind has taken him from his beginnings in Theoretical Physics to a successful career in finance, before the current obsession with developing HOOKE London as a prototype for 21st century medicine.

From his early fascination with Euclidean Geometry, Lev was driven to build simple models of our complex world. He honed this art working towards his PhD in 1989 with the top scientists of the Landau school in Moscow, before moving to the US and discovering that the skill was in high demand on Wall Street. In 1995 he joined the infamous Fixed Income Arbitrage group at Salomon Brothers and then went on to manage hedge fund portfolios at Moore Capital in London.

Having started regular endurance training at the age of 48, Lev was fascinated to uncover an enormous untapped potential in himself. This led him to become a keen student of Geroscience and to an increasing realisation that the potential of modern medicine is barely understood or realised. In 2019 Lev decided to change all that by launching HOOKE to prove that everyone’s life can be enhanced and extended by thoughtful application of the modern Life Sciences.

Lev continues training seriously, trying to be an exemplary HOOKE member No.1. He is also engaged with a few other curious Salomon Brothers alumni, collectively known as the Horn Fellowship, in helping the University of Cambridge to bridge the gap between science and policy. Long term, Lev hopes to help start a revolution in school education, which he believes is even less fit for our age than medicine…

Prof. Pierre-Marc Bouloux Prof. Dave Collins Dr David Porter Dr Dina Radenkovic Mark Roberts Mark Boyden Kate Woolhouse Alexis Kemp Lev Mikheev

THE TEAM FOUNDER

19

Our Scientific Advisory Board

HOOKE

20

Dr ERIC VERDIN is the President and CEO of the Buck Institute for Research on Aging – a pioneering biomedical research institute dedicated to ageing and age-related disease.

A native of Belgium, Dr Verdin received his Doctorate of Medicine (MD) from the University of Liege and completed additional clinical and researchtraining at Harvard Medical School. He has held faculty positions at the Universityof Brussels, the National Institutes of Health (NIH), and the Picower Institutefor Medical Research. Dr Verdin is also currently a professor of medicine at theUniversity of California, San Francisco.

He joined the Gladstone Institute of Virology and Immunology in 1997, becoming the associate director in 2004. In 2016 Dr Verdin established his laboratory at the Buck Institute for Research on Aging to study the relationship between ageing and the immune system.

He is in the top one percent of cited scientists and has been recog-nised for his research with a Glenn Award for Research in Biological Mechanisms of Aging and a senior scholarship from the Ellison Medical Foundation. He has published more than 250 scientific papers and holds more than 15 patents.

He is an elected member of several scientific organisations, inclu- ding the American Association for the Advancement of Science, the American Society for Clinical Investigation, and the Association of American Physicians. He also serves on the advisory council of the National Institute on Drug Abuse at the National Institutes of Health.

Dr Verdin has extensive experience working with biotech companies, including Novartis, Roche, Pfizer, and now HOOKE.

Dr Eric Verdin Dr Satchidananda Panda Prof. Paul Fletcher Dr David Furman

SCIENTIFIC ADVISORY BOARD CHIEF SCIENTIFIC ADVISOR

21

Dr SATCHIDANANDA (SATCHIN) PANDA is a leading expert in the field of circadian rhythm research. He was born and raised in India and migrated to the United States for his higher studies. He joined the graduate program at the Scripps Research Institute in California, where he studied the circadian oscillator mechanism in plants and after receiving his PhD in 2001, he pursued postdoctoral research in Dr John Hogenesch’s lab at the Genomics Institute of the Novartis Research Foundation, San Diego.

His research focuses on how circadian clocks in every organ and brain region work together to orchestrate the optimum timing for gene functions. He also studies how our daily habits or our environment affect circadian clocks. His research has led him to make several notable contributions to the field of chronobiology. In particularly he established that ‘time restricted feeding’ can be pivotal to preventing or curing metabolic disease and avoiding the chronic diseases of old age. He also discovered the pathways by which blue light affects our circadian clock, regulating mood and sleep patterns.

He is a Professor at the Salk Institute and a founding executive member of the Center for Circadian Biology at the University of California, San Diego. Dr Panda is also a Pew Scholar and a recipient of the The Julie Martin Mid-Career Award in Aging Research.

Dr Panda is the author of the book “The Circadian Code”.

Dr Eric Verdin Dr Satchidananda Panda Prof. Paul Fletcher Dr David Furman

SCIENTIFIC ADVISORY BOARD BOARD MEMBER

22

Professor Paul Fletcher trained in medicine and psychiatry before taking a PhD in cognitive neuroscience and was elected the Bernard Wolfe Professor of Health Neuroscience at the University of Cambridge in 2008. He uses combinations of pharmacological challenges, neuroimaging and larger scale behavioural studies in healthy and clinical populations, with the aim of understanding the basis of learning and decision-making in the human brain. His work is supported by a Wellcome Trust Investigator award.

A central principle of his research is that the brain is occupied in the process of forming predictions and associations to minimise error and uncertainty and to maximise reward. The cognitive and reflective processes engaged with this goal can conflict with underlying automatic and habitual processes. The end result may be that our behaviours can seem irrational and in conflict with our longer term goals and plans. Given that major global non-communicable diseases are profoundly influenced by health-harming decisions and behaviours, understanding how body, brain and environmental signals are integrated and how they shape these behaviours will be a crucial part of improving health.

Paul is also very interested in how video game and related technologies may play a key part in representing and promoting mental health. Working with the video game studio, Ninja Theory Ltd, he was a member of the team who made the video game Hellblade: Senua’s Sacrifice which won five BAFTAs and several other awards for its portrayal of mental illness.

Paul has been elected as a Fellow of the Academy of Medical Sciences.

Dr Eric Verdin Dr Satchidananda Panda Prof. Paul Fletcher Dr David Furman

SCIENTIFIC ADVISORY BOARD BOARD MEMBER

23

Dr DAVID FURMAN is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and an Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina.

Dr Furman obtained his doctoral degree in immunology from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his postdoctoral training at the Stanford School of Medicine, Dr Furman focused on the application of advanced analytics to study the ageing of the immune system in humans.

During a sabbatical year at University of Bordeaux, France, Dr Furman studied the involvement of the endocrine and immune systems in human ageing and in kidney transplantation, and then helped to create the Systems Biology Department at the Sidra Medical Research Center in Doha, Qatar. Before joining as a Principal Investigator at the National Scientific and Research Council, Buenos Aires, Argentina, Dr Furman returned to Stanford as Senior Scientist at the Institute for Immunity, Transplantation and Infection (ITI), where his work involved the use of Machine Learning tools to better define the role of the immune system in cardiovascular ageing.

Dr Furman has published nearly thirty scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others.

Dr Eric Verdin Dr Satchidananda Panda Prof. Paul Fletcher Dr David Furman

SCIENTIFIC ADVISORY BOARD BOARD MEMBER

28

Sample itinerary

HOOKE

29Consultation

FRIDAY 4TH DECEMBER

You will then be introduced to one of our clinical team who will explain the HOOKE programme to you in greater detail, and discuss your health goals and any current concerns. They will answer any initial questions, and understand your needs and preferences.

Following this Initial Consultation, you will be given a selection of wearable devices. The purpose of each will be explained to you by the health team.

10:30 INITIAL CONSULTATION with Dr David Porter

60 mins (Zoom)

Screening Day One

MONDAY 7TH DECEMBER

Please fast from 22:00 the night prior; plain water is allowed

07:00 CAR COLLECTION FROM HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class

30 mins

07:30 BLOOD TESTING The Doctor’s Laboratory 76 Wimpole Street W1G 9RT

60 mins

Please note a urine and stool sample will also be taken at TDL

08:30 BREAKFAST DELIVERY per your request to King Edward VII

King Edward VII 5–10 Beaumont St W1G 6AA

30 mins

09:00 FULL MEDICAL CONSULTATION with Prof. Bouloux

King Edward VII 5–10 Beaumont St W1G 6AA

90 mins

11:00 FULL BODY MRI in the imaging department

120 mins

13:00 CAR TO TAKE YOU HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class

30 mins

13:30 LUNCH DELIVERY to home

15:00 BRAIN HEALTH AND PERFORMANCE with Prof. Dave Collins

60 mins (Zoom)

Screening Day Two

MONDAY 9TH DECEMBER

Please fast from 22:00 the night prior; water, black tea and black coffee are allowed

08:30 CAR COLLECTION FROM HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class

30 mins

09:00 IN-BODY, FITNESS AND MSK with Dr David Porter & Mark Roberts

Personal Space London Leconsfield House W1J 5JA

90 mins

10:45 BREAKFAST DELIVERY per your request to your home

30 mins

12:00 VIRTUAL NUTRITIONAL CONSULTATION with Dr Dina Radenkovic

60 mins (Zoom)

30Post-screening

MONDAY 21ST DECEMBER 08:30 REPORT PRESENTATION

with Dr David Porter & Dr Dina Radenkovic 120 mins (Zoom) Please note a copy of your report will be emailed to you 2 hours prior to your Consultation

MONDAY 28TH DECEMBER

10:30 FOLLOW UP NUTRITIONAL CONSULTATION with Dr Dina Radenkovic 60 mins (Zoom)

12:00 FOLLOW UP BRAIN HEALTH AND PERFORMANCE CONSULTATION with Prof. Dave Collins 60 mins (Zoom)

MONDAY 4TH JANUARY

08:30 CAR COLLECTION FROM HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class 30 mins

09:00 FOLLOW UP MEDICAL CONSULTATION with Prof. Bouloux King Edward VII 5-10 Beaumont St W1G 6AA 60 mins

10:00 CAR COLLECTION FROM HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class 30 mins

10:30 FOLLOW UP FITNESS AND MSK with Dr David Porter & Mark Roberts Personal Space London Leconsfield House W1J 5JA 60 mins

11:30 CAR TO TAKE YOU HOME Driver Details: Alan Smith Drive Number: 07645 876321 Car Details: Merc S Class 30 mins

For further information please contact: [email protected]

© HOOKE 2021. Health and Longevity Optimisation Ltd. t/a HOOKE Company No. 11928940


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