Capability of Low-Cost Prolotherapy:

Where the Bar is Set.

AAOM 29th Annual Conference April 18-21 2012K. Dean Reeves, M.D.

Clinical Associate ProfessorUniversity of Kansas

KNEE OA EXAMPLE

Patient 3• 68 year old, 186 pounds, 168 cm height, with 36

months of left knee pain. • NRS L knee pain 8/10, 10 to 110 flexion range, 3

block walking distance. • First arthroscopy 9/17/10. • 6 injections of 10 ml 12.5% dextrose/0.45 normal

saline 10/9/10 through 4/20/11.• NRS L knee pain 3/10, 8 block walking distance.

• Second arthroscopy 5/8/11.

Knee X-Rays Pre Treatment

R L

Pre Treatment Picture: Section

Post Treatment: Pre Biopsy

Post Treatment: Post Biopsy

5125 -7 cartilaginous zone proximal to the articular surface, predominantly hyaline, with slight "clustering" condrocítico. H & E Obj 10 x

5125-8 Detail of the previous H & E Obj 20 xGrowth predominant hyaline

5125 -10: Obj PAS staining 10 x Periodic acid-Schiff (PAS) A staining method used to

detect glycogen and other polysaccharides in tissues.

11-5125 pol and 11-5125 pol 2: Cartilage with Polarized Light. Fibrillary not detected.

11-5125 and SAF 11-5125 SAF b: cartilage stained with Safranin / Light Green

OSD EXAMPLE

•“POEMs” = "Patient-Oriented Evidence that Matters”. •This is from January 7, 2012. •Avg 24/3000 articles reviewed per month.