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SKIN and SOFT TISSUESKIN and SOFT TISSUE
Celso M. Fidel, MD,FPSGS,FPCSCelso M. Fidel, MD,FPSGS,FPCS
Diplomate Philippine Board o S!r"er#Diplomate Philippine Board o S!r"er#
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Introd!$tionIntrod!$tion
SKINSKINConsidered as a sin"le anatomi$Considered as a sin"le anatomi$
ph#siolo"i$ph#siolo"i$
!nit!nit % to %.& s'. m in area% to %.& s'. m in area
Prote$ts the (od# (earin" the (r!nt oProte$ts the (od# (earin" the (r!nt o
in)!rio!s e*e$ts o e+ternalin)!rio!s e*e$ts o e+ternalenironmentenironment
SOFT TISSUESOFT TISSUE
Com rises a(o!t &- o the total (odComprises a(o!t &- o the total (od#
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SKIN INCISIONSSKIN INCISIONSChoice of known skin lines of relaxed tensionChoice of known skin lines of relaxed tension
Applying principles of effective concealmentApplying principles of effective concealment
and camouflageand camouflage
Considers dynamic muscle action and effect ofConsiders dynamic muscle action and effect of
gravity on skin and subcutaneous tissuegravity on skin and subcutaneous tissue Junctions of body planesJunctions of body planes
Lines of elevations of facial featuresLines of elevations of facial features
Lines of LangersLines of LangersContour Lines of junctions of body planesContour Lines of junctions of body planes
Lines of DependencyLines of Dependency
lective Lines that show when patient smileslective Lines that show when patient smiles
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!kin!kin
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S/inS/in
"revent fluid loss"revent fluid loss
#emperature control#emperature control
lasticity and supportlasticity and support
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
C$%&%'#ALC$%&%'#AL
#(A)*A#'C#(A)*A#'C
'%+LA**A#$(,'%+LA**A#$(,
%$"LA!#'C%$"LA!#'C
-%'&%-%'&%
*AL'&%A%#*AL'&%A%#
$#.( L!'$%!$#.( L!'$%! *#A!#A#'C !/'% L!'$%*#A!#A#'C !/'% L!'$%
+$('C% -$D, &(A%)L$*A+$('C% -$D, &(A%)L$*A
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
CONGENIT01CONGENIT01
0. Dermoid C#st0. Dermoid C#st
Ori"inate rom tiss!e entrapped d!rin"Ori"inate rom tiss!e entrapped d!rin"
!sion o em(r#oni$ pro$esses!sion o em(r#oni$ pro$esses
1ined (# s'!amo!s $ells and ma#1ined (# s'!amo!s $ells and ma#$ontain$ontain
Stra2 $olored Fl!idStra2 $olored Fl!id
Chees# materialChees# material 1an!"o 3air1an!"o 3air
Generall# $#st in the head is operatedGenerall# $#st in the head is operated
at O4at O4
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
DermoidDermoid
+re0uently occurs in the+re0uently occurs in the
midline over the 1midline over the 1
$cciput$cciput %asal dorsum%asal dorsum
*id2frontal region of scalp*id2frontal region of scalp
!acral area!acral area Abdominal areasAbdominal areas
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DermoidDermoid
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DermoidDermoid
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
C$%&%'#ALC$%&%'#AL
C3 -ranchiogenic sinusesC3 -ranchiogenic sinuses Are located anterior to medial edge ofAre located anterior to medial edge of
sternocleidomastoid musclesternocleidomastoid muscle
Arise from either 'st45Arise from either 'st45ndndor 6or 6rdrd branchialbranchial
archarch
Located anterior to ear if coming from 'stLocated anterior to ear if coming from 'st
#(A)*A#'C#(A)*A#'C
A3 7oundsA3 7ounds AbrasionsAbrasions Lacerated woundsLacerated wounds
"unctured wounds"unctured wounds 'ncised wounds'ncised wounds
AvulsionAvulsion
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AvulsionAvulsion
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'ncised 7ounds'ncised 7ounds
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
#(A)*A#'C#(A)*A#'C
-3 "neumatic tire injury-3 "neumatic tire injury
!pecial type of laceration!pecial type of laceration
(otating tire 8chews up9 soft tissue and tears it off from(otating tire 8chews up9 soft tissue and tears it off from
underlying deep fascia transecting the investing bloodunderlying deep fascia transecting the investing bloodvessels3vessels3
Common error ofCommon error of merely suturing the woundmerely suturing the woundandand failing tofailing to
recogni:erecogni:emassive avulsion of skin and subcutaneousmassive avulsion of skin and subcutaneoustissue would result in more extensive necrosis3tissue would result in more extensive necrosis3
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
#(A)*A#'C#(A)*A#'C
-3-3 "neumatic tire injury"neumatic tire injury
*anagement*anagement Damage area cleanedDamage area cleaned
Divitali:ed tissue debridedDivitali:ed tissue debrided
xtremity splintedxtremity splinted
(aw area skin2grafted(aw area skin2grafted
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1ESIONS OF SKIN 0ND SOFT TISSUE1ESIONS OF SKIN 0ND SOFT TISSUE
#(A)*A#'C#(A)*A#'C
C3 -urnsC3 -urns
#hermal#hermal $pen flame$pen flame
-oiling water-oiling water
!moke inhalation injuries!moke inhalation injuries
ChemicalChemical
lectricallectrical
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"artial #hickness -urns"artial #hickness -urns
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$cclusive Dressing w; Duoderm$cclusive Dressing w; Duoderm
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OT3E4 1ESIONSOT3E4 1ESIONS
/L$'D!/L$'D! Accepted form of treatmentAccepted form of treatment
!urgery with post
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OT3E4 1ESIONSOT3E4 1ESIONS
3ematoma3ematomaD!e to r!pt!re o a (lood esselD!e to r!pt!re o a (lood essel
Bl!ish or p!rplish s2ellin" o s/in andBl!ish or p!rplish s2ellin" o s/in ands!($!taneo!s tiss!es!($!taneo!s tiss!e
Ma# o$$!r as postoperatie $ompli$ationMa# o$$!r as postoperatie $ompli$ation
Treated $onseratiel#Treated $onseratiel#
S!r"i$al ea$!ation li"ate (leedersS!r"i$al ea$!ation li"ate (leeders
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INF10MM0TO4: CONDITIONSINF10MM0TO4: CONDITIONS
--
>irulent or massive>irulent or massive infectioninfectiontogether with lowtogether with lowpatient resistancepatient resistance4 results in skin and soft4 results in skin and softtissue losstissue loss
!kin grafting!kin graftingindicated once infection isindicated once infection iscontrolled and granulation tissue hascontrolled and granulation tissue has
developeddeveloped
#issue loss often seen in#issue loss often seen in malnourishedmalnourishedinfantsinfantsand children where ordinary pyogenicand children where ordinary pyogenic
infection produces massive skin necrosisinfection produces massive skin necrosis
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CellulitisCellulitis
CC ll liti
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CellulitisCellulitis
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CellulitisCellulitis
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+uruncle+uruncle
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+uruncle+uruncle
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CarbuncleCarbuncle
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditionsA3 Common 7artsA3 Common 7arts
>errucae >ulgaris2>errucae >ulgaris2
$ccurs in 5$ccurs in 5ndnd decade of lifedecade of life
*aybe transmitted by direct or indirect contact*aybe transmitted by direct or indirect contact
Caused by a member of the papovavirusCaused by a member of the papovavirus
'nvades stratum spinosum epidermidis causing'nvades stratum spinosum epidermidis causing
papillomatosispapillomatosis
Located in hands and feetLocated in hands and feet
(ough4 grayish papillomatous nodular or(ough4 grayish papillomatous nodular or
elevated pla0ueselevated pla0ues
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>erruca >ulgaris>erruca >ulgaris
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>erruca >ulgaris>erruca >ulgaris
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>erruca >ulgaris>erruca >ulgaris
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditionsA3Common 7artA3Common 7art
>errucae >ulgaris2>errucae >ulgaris2
Can become tenderCan become tender 7ill resolve spontaneously7ill resolve spontaneously
"roblematic lesions can be treated"roblematic lesions can be treated
by1by1Curettage and electrodessicationCurettage and electrodessication
+ree:ing with li0uid nitrogen+ree:ing with li0uid nitrogen Chemotherapy with caustic agentChemotherapy with caustic agent
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
Beni"n $onditionsBeni"n $onditions
B. C#st9B. C#st9are ;!id 6lled $aities inare ;!id 6lled $aities ins!($!taneo!s tiss!e 2hi$h ma#s!($!taneo!s tiss!e 2hi$h ma#resem(le solid t!morresem(le solid t!mor
%. Epidermal in$l!sion C#st%. Epidermal in$l!sion C#st Epidermal $ells are trapped inEpidermal $ells are trapped in
s!($!taneo!ss!($!taneo!s
tiss!e. Des'!amation leads to thetiss!e. Des'!amation leads to the$reation$reation
o a $ait#o a $ait#
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Se(a$eo!s C#stsSe(a$eo!s C#sts
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0ppli$ation o 0nesthesia0ppli$ation o 0nesthesia
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Start o E+$isionStart o E+$ision
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The 6nal o!t$omeThe 6nal o!t$ome
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Se(a$eo!s $#st in e#elidsSe(a$eo!s $#st in e#elids
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!tellate !uturing of &anglion!tellate !uturing of &anglion
CystCyst
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!tellate !uturing of &anglion!tellate !uturing of &anglion
CystCyst
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Lines of LangersLines of Langers
O S C CO O SNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditionsC3 >ascular #umorsC3 >ascular #umors?3?3 Capillary HemangiomasCapillary Hemangiomas
@"ort wine2 !tain@"ort wine2 !tain
found in thefound in the
face4face4
chest4chest4
extremitiesextremities
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditions
C3 >ascular #umorsC3 >ascular #umors
53'mmature .emangioma53'mmature .emangioma
+ound in the head4 neck4 chest and+ound in the head4 neck4 chest and
extremities of infantsextremities of infants
levated4 red4 soft4 compressible tumorsBlevated4 red4 soft4 compressible tumorsB
fre0uently enlarges during ?st year of lifefre0uently enlarges during ?st year of life
)ndergoes spontaneous regression during)ndergoes spontaneous regression during
the next 52 yearsthe next 52 years
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS-enign conditions-enign conditions
C3 >ascular #umorsC3 >ascular #umors6363 Cavernous .emangiomasCavernous .emangiomas
Compressible shows a wide channelCompressible shows a wide channel
w; loose connective tissue septaew; loose connective tissue septae
lined by embryonal endotheliumlined by embryonal endothelium
Lesions maybe nodular4 lobular or polypoidLesions maybe nodular4 lobular or polypoid
!urgery is the treatment of choice!urgery is the treatment of choice
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS-enign conditions-enign conditions
C3 >ascular #umorsC3 >ascular #umorsE3 !pider %evi @ #elangiectasiaE3 !pider %evi @ #elangiectasia
occur in all age groups commonoccur in all age groups common
in the face4 chest extremitiesin the face4 chest extremities
Arise during pregnancy in cirrhosisArise during pregnancy in cirrhosis
Central arteriole with vesselCentral arteriole with vessel
resembling venules radiating fromresembling venules radiating from
the centerthe center
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditionsD3 LipomaD3 Lipoma
-enign encapsulated subcutaneous-enign encapsulated subcutaneous
lesion4 single but maybe multiplelesion4 single but maybe multiple Are most common on the neck4Are most common on the neck4
shoulder4 back4 thighshoulder4 back4 thigh
$ccasionally fluctuates under the$ccasionally fluctuates under the
palpating fingerpalpating finger
>isible lobulation upon stretching the>isible lobulation upon stretching the
skinskin
Li
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LipomaLipoma
A ill *
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Axillary *assAxillary *ass
* %
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*ass %ape*ass %ape
A th >iA th >i
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Another >iewAnother >iew
( d f !( d f !
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(eady for !urgery(eady for !urgery
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditions
3 %erve #umors3 %erve #umors
?3 %eurilemomas?3 %eurilemomas
$riginates from !chwanns cells of$riginates from !chwanns cells of
peripheral nerve sheaths and mayperipheral nerve sheaths and may
not adhere to nervenot adhere to nerve
#reatment is by excision#reatment is by excision
NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
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NEOP10STIC CONDITIONSNEOP10STIC CONDITIONS
-enign conditions-enign conditions
3 %erve #umors3 %erve #umors
53 %eurofibroma153 %eurofibroma1
*ay occur as single or multiple as in*ay occur as single or multiple as in
>on (ecklinghausens disease>on (ecklinghausens disease
+ibromas of the dermis+ibromas of the dermis
%eurofibromas @multiple%eurofibromas @multiple 7idespread skin pigmentation at7idespread skin pigmentation at
back@coffee2 colored spotsback@coffee2 colored spots
atho nomonicatho nomonic
% +ib% +ib
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%euro +ibroma%euro +ibroma
P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
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P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
?3 Actinic /eratosis?3 Actinic /eratosis
(ough4 scaly epidermal lesion in areas of the(ough4 scaly epidermal lesion in areas of the
body subjected to chronic sun exposurebody subjected to chronic sun exposure
66rdrdand Eand Eththdecade and ?FG to 5FG willdecade and ?FG to 5FG will
undergo malignant transformationundergo malignant transformation
'f benign4 excision or cryotherapy'f benign4 excision or cryotherapy H2fluorouracil for patients with manyH2fluorouracil for patients with many
keratosiskeratosis
A ti i / t i
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Actinic /eratosisActinic /eratosis
P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
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P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
5353 -owens Disease-owens Disease 'ntraepidermal s0uamous cell carcinoma or'ntraepidermal s0uamous cell carcinoma or
Carcinoma in situ of the skinCarcinoma in situ of the skin
7ell defined erythematous pla0ue covered7ell defined erythematous pla0ue covered
by an adherent scaly yellow crustby an adherent scaly yellow crust
%o lymphatics in the layer affected4 no%o lymphatics in the layer affected4 no
potential for metastasispotential for metastasis
EEththto Ito Iththdecade of lifedecade of life
Arsenic ingestion and viruses implicated asArsenic ingestion and viruses implicated as
etiologic agentsetiologic agents
#reatment#reatmentsame as actinic keratosissame as actinic keratosis
- Di- Di
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-owens Disease-owens Disease
P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
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P4EM01IGN0NT SKIN 1ESIONP4EM01IGN0NT SKIN 1ESION
3.3. KeratoacanthomaKeratoacanthoma
Locally destructive skin lesion found inLocally destructive skin lesion found in
the head, neck, & upper extremitiesthe head, neck, & upper extremities
Fast groing ith!Fast groing ith!
smooth rounded "orders & keratiticsmooth rounded "orders & keratitic
center plugcenter plug
#t may regress ithin six months#t may regress ithin six months
$xcision is treatment of choice$xcision is treatment of choice
%uamous cell cancer is found in ' of%uamous cell cancer is found in ' of
the lesions "iopsiedthe lesions "iopsied
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NE>I 5MO1ES?NE>I 5MO1ES?
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NE>I 5MO1ES?NE>I 5MO1ES? "igmented lesions of skin that fre0uently"igmented lesions of skin that fre0uently
concern the patient because of the fearconcern the patient because of the fearof malignancyof malignancy
Average white male has ?H to 5F nevi so totalAverage white male has ?H to 5F nevi so totalexcision is unreasonableexcision is unreasonable
Clinical diagnosis is of prime importanceClinical diagnosis is of prime importance
because malignant transformation can occurbecause malignant transformation can occur
7ell circumscribed lesions with uniform color7ell circumscribed lesions with uniform color
rarely progress to malignancyrarely progress to malignancy
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pidermal %evuspidermal %evus
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.alo %evus.alo %evus
BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
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?3 Junctional %evi?3 Junctional %evi
Dark4 flat4 smooth4 lesions about ?mmDark4 flat4 smooth4 lesions about ?mm
to 5cm diameterto 5cm diameter
$ccasionally hairy and develop from$ccasionally hairy and develop from
the basal layer of epidermisthe basal layer of epidermis
%evi that are located in the palms and%evi that are located in the palms and
soles are usually junctionalsoles are usually junctional
Can develop into malignant melanomaCan develop into malignant melanoma
but this rarely occurs before pubertybut this rarely occurs before puberty
BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
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BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
553 Compound %evi3 Compound %evi
-rown to black4 well circumscribed-rown to black4 well circumscribed
lesionslesions
)sually less than ? cm in diameter)sually less than ? cm in diameter
*aybe elevated and are fre0uently*aybe elevated and are fre0uently
hairy arising from epidermal2hairy arising from epidermal2dermal interface and within thedermal interface and within the
dermisdermis
*alignant transformation is rare*alignant transformation is rare
BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
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BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
63 'ntradermal %evi63 'ntradermal %evi
Are light colored well circumscribedAre light colored well circumscribedlesion less than ? cm in diameterlesion less than ? cm in diameter
.airs are usually present and the cell.airs are usually present and the celldistribution is in the dermisdistribution is in the dermis
*alignant transformation is rare*alignant transformation is rare
E3 -lue %eviE3 -lue %evi
!mooth4 hairless lesion about ? cm!mooth4 hairless lesion about ? cm
Arise from the dermisArise from the dermis
*ali nant de eneration is rare
BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
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BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
5.5. &iant "igmented %evi&iant "igmented %evi
-rown to black4 hairy lesions with an-rown to black4 hairy lesions with an
irregular nodular surfaceirregular nodular surface
+re0uently involve more than ? s03 inch+re0uently involve more than ? s03 inch
foot of body surface and arise from thefoot of body surface and arise from the
dermis and junctional areasdermis and junctional areas
+re0uently described in terms of distribution+re0uently described in terms of distribution
as bathing trunk 8vest49 sleeve oras bathing trunk 8vest49 sleeve orstockingstocking
*alignant degeneration is ?FG*alignant degeneration is ?FG
xcision with margin of normal tissuexcision with margin of normal tissue
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BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
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BENIGN PIGMENTED 1ESIONSBENIGN PIGMENTED 1ESIONS
#(A#*%##(A#*%#
-3 'ndications for excision of any-3 'ndications for excision of anypigmented lesion include1pigmented lesion include1
?3?3 Changes in color4 si:e4 shapeChanges in color4 si:e4 shape4 or4 or consistencyconsistency
53 "ain53 "ain 63 !atellite nodules63 !atellite nodules
E3 (egional adenopathyE3 (egional adenopathy
C3 xcisional biopsy w; normal marginsC3 xcisional biopsy w; normal margins
D3 +or large lesions4 a full thicknessD3 +or large lesions4 a full thickness
wedge biopsy including a small areawedge biopsy including a small area
of normal skin should be takenof normal skin should be taken
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS*alignant *elanoma*alignant *elanoma
A3 pidemiologyA3 pidemiology ?3 incidence is ?6 new cases;?3 incidence is ?6 new cases; ?FF4FFF?FF4FFF;year;year
representing an increase of HFGrepresenting an increase of HFG
53 occurs in H53 occurs in Hththdecade4 rare in childrendecade4 rare in children
63 some 5FG to 6FG arise in head 63 some 5FG to 6FG arise in head
neckneck
E3 incidence is e0ual in males and inE3 incidence is e0ual in males and in
femalesfemales
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS*alignant *elanoma*alignant *elanoma
xposure to sunlight3 +air skinnedxposure to sunlight3 +air skinnedwhites with fre0uent directwhites with fre0uent direct
exposure to the sun often affectedexposure to the sun often affected
'n men chest4 back4 upper extremities'n men chest4 back4 upper extremities
'n women affects back upper and'n women affects back upper and
lower extremitieslower extremities
Detection of melanoma is determinedDetection of melanoma is determined
by changes in the color4 si:e andby changes in the color4 si:e and
sha e of a nevusshape of a nevus
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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*alignant *elanoma*alignant *elanoma
C3 Classification based on &ross andC3 Classification based on &ross and .istologic appearance.istologic appearance
?3 !uperficial !preading *elanoma?3 !uperficial !preading *elanoma
Accounts for FG of all melanomaAccounts for FG of all melanoma
Can be present on any part of theCan be present on any part of the
body but more at the back legsbody but more at the back legs
HHththdecade of lifedecade of life
'rregular borders4 varied color'rregular borders4 varied color
))pperpperdermis w; lateraldermis w; lateraljunctional spreadjunctional spread
&enerally prognosis is good&enerally prognosis is good
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
*alignant *elanoma*alignant *elanoma
53 %odular *elanoma53 %odular *elanoma
Accounts for ?HG of all melanomaAccounts for ?HG of all melanoma
IIthth
decade of lifedecade of life -lue black lesion on any part-lue black lesion on any part
of bodyof body
>ertical spread rapid dermal>ertical spread rapid dermal
invasioninvasion
"rognosis is poor"rognosis is poor
%odular *elanoma%odular *elanoma
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%odular *elanoma%odular *elanoma
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSG S O S
*alignant *elanoma*alignant *elanoma
E3 Lentigo *aligna @ *elanotic freckle ofE3 Lentigo *aligna @ *elanotic freckle of
.utchinson.utchinson
#he least commonB H#he least commonB Hththdecadedecade
-rown black w; elevated nodules w;in a-rown black w; elevated nodules w;in a
smooth frecklesmooth freckle
+re0uent in the head4 neck4 hand+re0uent in the head4 neck4 hand
!low growth in radial direction w; cells in!low growth in radial direction w; cells in
the upper dermisthe upper dermis
>ertical extension is fre0uent>ertical extension is fre0uent
"rognosis is excellent"rognosis is excellent
Lentigo *alignaLentigo *aligna
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Lentigo *alignaLentigo *aligna
Lentigo *alignaLentigo *aligna
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Lentigo *alignaLentigo *aligna
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
*alignant *elanoma*alignant *elanoma
CLA(/! CLA!!'+'CA#'$%CLA(/! CLA!!'+'CA#'$%
Level ? #umor confined to epidermisLevel ? #umor confined to epidermis
Level ??Level ?? #umor invades papillary#umor invades papillarydermdermisisLevel ???2#Level ???2#umorumorfills the papillaryfills the papillarydermdermisis bubutt
ddoes not invadeoes not invadereticureticularlardermdermisis
Level ?>2#uLevel ?>2#umor invades the reticularmor invades the reticulardermisdermis
Level > < #umor invades subcutaneousLevel > < #umor invades subcutaneous
tissue @ +at tissue @ +at
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS*alignant *elanoma*alignant *elanoma -(!L$7 CLA!!'+'CA#'$%-(!L$7 CLA!!'+'CA#'$%
'nvolves measuring the deep invasion'nvolves measuring the deep invasion precisely in millimeterprecisely in millimeter
"atients with Clark level ?4 ??4 ???4"atients with Clark level ?4 ??4 ???4lesion w;a depth of invasion that islesion w;a depth of invasion that is
less than F3 are at low risk forless than F3 are at low risk for
metastasismetastasis
"atients w; level ?> or > and w; a"atients w; level ?> or > and w; a
depth of invasion greater than ?3H mmdepth of invasion greater than ?3H mm
are at high risk for distant metastasisare at high risk for distant metastasis
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS*alignant *elanoma*alignant *elanoma
'n order to complete the staging'n order to complete the staging #horough histological and physical#horough histological and physical
examination are necessaryexamination are necessary
'nclude ancillary work2up like'nclude ancillary work2up like complete blood countcomplete blood count
urinalysisurinalysis
chest x2raychest x2ray ?5 test se0uential multiple?5 test se0uential multiple
analysis @ !*A 2?5 analysis @ !*A 2?5
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
*alignant *elanoma*alignant *elanoma #reatment#reatment11 A3 xcisionA3 xcision
-3 (esection-3 (esection
C3 Adjuvant #herapyC3 Adjuvant #herapy
(egional hyperthermic perfusion(egional hyperthermic perfusion
ChemotherapyChemotherapy 'mmunotherapy'mmunotherapy (adiotherapy(adiotherapy
M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
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M01IGN0NT 1ESIONSM01IGN0NT 1ESIONS
Mali"nant MelanomaMali"nant Melanoma
Pro"nosis@Pro"nosis@
Disease $on6ned at primar# site &Disease $on6ned at primar# site &
#ear#ear s!rial is A-9-s!rial is A-9-
I re"ional l#mph nodes are inoledI re"ional l#mph nodes are inoled
s!rial "oes do2n to =- to &-s!rial "oes do2n to =- to &-
Patients 2ho hae distant or is$eralPatients 2ho hae distant or is$eral
metastasis are !s!all# dead 2ithinmetastasis are !s!all# dead 2ithin
B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
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B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
A malignant skin tumorA malignant skin tumorcharacteri:ed by slow growthcharacteri:ed by slow growth
and very rare distantand very rare distant
metastasismetastasis&enerally occurs in the head&enerally occurs in the head
and neckand neck+ound most commonly in+ound most commonly in
individuals of %orthernindividuals of %orthern
uro ean Descenturopean Descent
-asal Cell Carcinoma-asal Cell Carcinoma
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-asal Cell Carcinomaasa Ce Ca c o a
B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
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Etiolo"#Etiolo"#
It has (een asso$iated 2ith@It has (een asso$iated 2ith@ eroderma pi"mentos!meroderma pi"mentos!m
Basal $ell ne!s s#ndromeBasal $ell ne!s s#ndrome
Ne!s se(a$eo!sNe!s se(a$eo!s Unsta(le (!rn s$arUnsta(le (!rn s$ar
Dermatitis s!()e$ted to radiation therap#Dermatitis s!()e$ted to radiation therap#
Clini$al Findin"sClini$al Findin"s 1esion has pearl# transl!$ent ed"es1esion has pearl# transl!$ent ed"es
Smooth eleation 2ith telan"ie$tati$Smooth eleation 2ith telan"ie$tati$
s!ra$es!ra$e
B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
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B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
#reatment#reatment
involves complete removal of the tumor toinvolves complete removal of the tumor to
achieve cure3 -'$"!, '! *A%DA#$(,achieve cure3 -'$"!, '! *A%DA#$(,
?3 Curettage and lectrodessication?3 Curettage and lectrodessication
HG cure rateHG cure rate
for lesions less than F35cmfor lesions less than F35cm
53 (adiation #herapy53 (adiation #herapy
FG cure rateBFG cure rateB
when tissue preservation is importantwhen tissue preservation is important
depigmentation and atrophy can occurdepigmentation and atrophy can occur
B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
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B0S01 CE11 C04CINOM0B0S01 CE11 C04CINOM0
#reatment#reatment63 xcision with primary Closure63 xcision with primary Closure A F3H cm margin from the grossly detectableA F3H cm margin from the grossly detectable
limit of the lesion ade0uate for curelimit of the lesion ade0uate for cure
HG cure rateHG cure rate
L% should be excised in continuityL% should be excised in continuity
if they are clinically positiveif they are clinically positive
(econstruction can be performed(econstruction can be performedin one settingin one setting
SU0MOUS CE11 C04CINOM0SU0MOUS CE11 C04CINOM0
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SU0MOUS CE11 C04CINOM0
't is more malignant in clinical behavior't is more malignant in clinical behaviorthan basal cell carcinomathan basal cell carcinoma
+ast growing and tends to metastasi:e to+ast growing and tends to metastasi:e to
regional L% plus wider local spreadregional L% plus wider local spreadtiologytiology
xposure to sunlightxposure to sunlight
+rom pre2malignant lesion+rom pre2malignant lesion
$ld burn scar$ld burn scar
xposure to arsenicals4 nitrates andxposure to arsenicals4 nitrates and
hydrocarbonshydrocarbons
!0uamous Cell Carcinoma!0uamous Cell Carcinoma
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00
SU0MOUS CE11 C04CINOM0SU0MOUS CE11 C04CINOM0
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SU0MOUS CE11 C04CINOM0SU0MOUS CE11 C04CINOM0Clini$al ManiestationsClini$al Maniestations
Ma# appear as a satellite nod!le or a $entralMa# appear as a satellite nod!le or a $entralareaarea
o !l$eration that ma# (e$ome en$r!stedo !l$eration that ma# (e$ome en$r!sted
o(s$!rin"o(s$!rin"
deeper inasiondeeper inasion
Common in the lips, paranasal olds and a+illaCommon in the lips, paranasal olds and a+illa
Treatment@Treatment@
is (ased !pon e+amination o the (iops#is (ased !pon e+amination o the (iops#
spe$imenspe$imen
E+$ision Biops# or lesion less than %$mE+$ision Biops# or lesion less than %$m
SU0MOUS CE11 C04CINOM0SU0MOUS CE11 C04CINOM0
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Treatment MethodsTreatment Methods
%. Ele$trodessi$ation%. Ele$trodessi$ation
For lesions less than %$m in diameterFor lesions less than %$m in diameter
For older indiid!alsFor older indiid!als
In patients 2ith re$!rren$e o t!morsIn patients 2ith re$!rren$e o t!mors
SU0MOUS CE11 C04CINOM0SU0MOUS CE11 C04CINOM0
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Treatment MethodsTreatment Methods
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Treatment MethodsTreatment Methods
=. 4adiation Therap#=. 4adiation Therap# Us!all# resered or adan$ed lesions inUs!all# resered or adan$ed lesions in
areasareas
2here s!r"i$al e+$ision leaes a2here s!r"i$al e+$ision leaes a$osmeti$all#$osmeti$all#
!na$$epta(le dee$t the nose, the e#elid,!na$$epta(le dee$t the nose, the e#elid,lipslips
Not !sed 2hen (one and $artila"e areNot !sed 2hen (one and $artila"e areinoledinoled
these re'!ire radi$al e+$isionthese re'!ire radi$al e+$ision
. MohHs S!r"er#. MohHs S!r"er#
99
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S2eat Gland T!morsS2eat Gland T!mors
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4are lesions arisin" rom the4are lesions arisin" rom thee$$rine ore$$rine or
apo$rine "landapo$rine "land
O$$!r in later lie as a sot tiss!eO$$!r in later lie as a sot tiss!emassmass
that has (een present or #earsthat has (een present or #ears
Metastasis toMetastasis to re"ional l#mphre"ional l#mphnodes arenodes are$ommon$ommon
$onsider disse$tion at time o initial$onsider disse$tion at time o initial
e+$isione+$ision
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