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2. Diagnosis of Skin Diseases

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    Diagnosis ofSkin Diseases

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    History and PhysicalExamination

    • 90% of skin diseases can be properly diagnosed withmeticulous history and proper physical examination.

    • In the history the chief complaint, onset, progression,

    associated symptoms, drug history, past medicalhistory, personal history, family history, race, systemreview are all important.

    •  The prinicipal steps in physical examination arepalpation and inspection.

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    Skin Lesions

    • lassi!ed as "#I$#&' ()*+#& (-I+)(I*+(.

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    Primary Skin Lesions

    $acule

    "atch

    "apule

    +odule

     Tumor"la/ue

    esicle

    "ustule

    1ullae

    2heal Telangiectasia

    bscess

    "etechiae, purpura ' ecchymosis

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    Macule

    • 3at, coloredlesion, 45cm indiameter, not

    raised above thesurface ofsurrounding skin

    • 6reckle 7 prototype

    of pigmentedmacule

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    Macule

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    patch

    • large8:cmdiametr;3at lesionwith a color

    di

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    Papule

    • small, solidlesion, 40.> cmin diameter, raised

    above the surfaceof surrounding skin' hence palpable

    • )g? white head in

    acne

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    Papule

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    Nodule

    • large 8 5 cm ;,!rm lesion raisedabove the surface

    of surrounding skin.• i

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    Tumor

    • solid,raisedgrowth :cm indiameter

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    Plaque

    • large 5cm, 3attoppedAplateau likeraised lesion, edges

    may either bedistinct 8 inpsoriasis ; orgradually blend

    with surroundingskin 8 inec=ematousdermatitis;

    • iameter greater

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    esicle

    • are small papule,3uid !lled lesion,45cm in diameter,

    raised above theplane ofsurrounding skin.6luid is often visible

    and the lesion aretranslucent

    • esicles in llergicontact ermatitis

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    Pustule

    • vesicle !lled withleukocytes ' pus45cm

    •  The presence ofpustule does notnecessarily signifythe the existance of

    infection

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    !"scess

    • localisedcollection of pus ina cavity, more than

    5 cm in diameter

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    "ulla

    • 3uid !lled ,raised, often atranslucent lesion

    5cm in diameterand it is the largerform of vesicles.

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    #heal

    • raised,erythematous,edematous,

    papule A pla/ue,usuallyrepresenting shortBlived vasodilatation

    andvasopermeability

    • )g? utricaria

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    telangiectasia

    • dilated super!cialblood vessel like

     C".

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    Petechiae$ purpura %ecchymosis

    • "etechiae 7 pinheadBsi=ed macules of extravascular blood in the dermis.

    • "etechiae are 3at.

    •  The larger ones are referred to as purpura

    • If bleeding involves deeper structures then it iscalled ecchymosis 

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    &urro'

    • linear or cuvillinear papule, caused byburrowing scabies mite

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    (omedones

    • plug of keratin and sebum wedged in dilatedpilosebaceous ori!ce.

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    Secondary Skin Lesions

    (cale

    rust

    )xcoriation

    )rosion6issure

    (inus

    (car

    trophy(triae

    icheni!cation

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    Scale

    • 3ake arising fromstratum corneumdAt excessive

    accumulation.• )g? psoriasis

     

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    (rust

    • ried exudate ofbody 3uids 8blood Aserous 3uid;

    •2hich might beeither yellow8 serous crust ;

      red 8hemorrhagiccrust ;

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    )lcer

    • n area of skinfrom which thewhole of epidermis

    ' atleast the upperpart of dermis hasbeen lost

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    Excoriation

    • inear, angularerosions that maybe covered by crust

    and are caused byscratching.

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    Erosion

    • rea of skindenuded8removed;by complete or

    partial loss ofepidermis.

    • +o associated lossof dermis

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    *issure

    • slitB shaped deepulcer

    • )g? irritant

    dermatitis of hands

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    Sinus

    • cavity or channelthat permits theescape of pus or

    3uid

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    Scar

    • change in theskin secondary totrauma or

    in3ammation• (ites may be

    erythematous,hypopigmented or

    hyperpigmenteddepending upontheir ageAcharacter.

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    Scar

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    !trophy

    n ac/uired loss ofsubstance .

    In skin, this mayappear as a depression

    with intact epidermis8 loss of dermal Asubdermal tissues ;

    *r appear as sites of

    shiny, delicate,wrinkled lesions8 epidermal atrophy ;

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    Striae

    • streak like,linear , atrophic,pink, purple or

    white lesion dAtchanges inconnective tissue

    • )g? cushings

    syndrome,pregnancy induced

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    Licheni+cation

    • distinctivethickening of skinthat is

    characteri=ed byaccenuated skinBfold markings.

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    Primary Skin Lesions

      Macule: 3at area of altered colour or texture 8less than 0.> cm;

      Patch: large macule 8more than : cm in diameter;  Papule: elevated solid lesion 8less than 0.> cm;

      Nodule: elevated solid lesion 8more than 0.> cm, diameter@thickness;

     

    Plaque: elevated area of skin of more than : cm indiameter8diameter the thickness;.

      Vesicle: 3uid !lled papule 8less than 0.> cm;

      Bulla: larger blister 8more than 0.> cm;   TD$*#B larger bullae or nodule8more than :cm;

      Pustule: collection of free pus

       Abscess: locali=ed collection of pus in a cavity 8more than 5 cm;

      Petechia, Ecchymosis, Purpura

      Telangiectasia

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    Secondary Skin Lesions

      Scale: 3ake from the horny layer  rust: dried serum, exudates or tissue 3uid

      !lcer: whole of the epidermis and part of dermis lost

      E"coriation: linear erosion or ulcer produced by

    scratching  Erosion: partial loss of the epidermis

      #issure: slit in the skin

      Sinus: channel that permits escape of pus or 3uid

      Scar: result of healing, normal structure replaced by!brous tissue

       Atrophy: thinning of skin.

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    !rrangement of Skin Lesions

    • iscreteAseparate

    • EroupedAcoalese

    • inear

    rcuate• ircinate

    • Eyrate

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    Distri"ution of Skin Lesions

    • (ymmetry, asymmetry

    • 6lexural, extensor

    • )xposed, overed

    "hoto• (ebaceous

    • ermatomalA(egmental

    • cral, entral

    "alms and soles

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    Special Techniques

    5. ). "ercutaneous Testing

    . $ite )xamination

    J. -*K )xamination

    L. T=ank (mear 

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    Principles of Treatment

    • rugs for skin diseases could be given topicaly,oraly, parentraly or intralesionaly.

    •  Topical therapy is the milestone

    • onsidering the active ingradient coupled with thevehicle is important.

    •  Topical preparations are classi!ed based on thevehicle.

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    •reams 

    •*intments•otions

    •(hampoos•"astes

    •Eels

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    Topical Steroids

    •  The most commonly used topical preparations

    • Improper use has led to signi!cant side e

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    Principles of using topicalsteroids

    • onHt use for uncertain diagnosis and cosmeticreason

    • 6irst treat concomittent infection

    • Dse the mildest steroid possible

    • onHt apply potent steroids to the baby skin, faceand intertreginous areas

    • onHt apply potent steroids more than two weeks.

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    Side E,ects of Steroids

    • ocal• 1alnching

    • trophy

    • cne form eruptions

    • Infections• Elaucoma

    • ataract

    • (ystemic side e


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