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www.wasad2019.org 2 nd International Congress of the World Association for Stress Related and Anxiety Disorders in conjunction with the Collaborative Research Center SFB TRR 58, Fear, Anxiety, Anxiety Disorders (funded by the DFG) Stress, Anxiety and Mental Health 03-05 October 2019 Würzburg, Germany Final Program
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www.wasad2019.org

2nd International Congress of the

World Association for Stress Related

and Anxiety Disorders

in conjunction with the

Collaborative Research Center SFB TRR 58,

Fear, Anxiety, Anxiety Disorders (funded by the DFG)

Stress, Anxiety and Mental Health

03-05 October 2019

Würzburg, Germany

Final Program

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Congress Venue

Julius-Maximilians-Universität Würzburg Building Z6

Hubland Süd (Zentrales Hörsaal- u. Seminargebäude)

Am Hubland

97074 Würzburg, Germany

Host Organization

World Association for Stress Related and Anxiety Disorders (WASAD)

Schwanenhof 4, 97070 Würzburg, Germany

Phone: +49 (0) 931 – 207 90248; Fax: + 49 (0) 931 – 207 90246

[email protected]

Affiliate Organizer

SFB-TRR 58 Fear, Anxiety, Anxiety Disorders

Institut für Physiologie I, Robert-Koch-Straße 27, 48149 Münster, Germany

Congress Presidents

Prof. Dr. H. C. Pape, Germany; Prof. Dr. A. J. Fallgatter, Germany

Local Organizing Committee

Chairs: M. Gamer and P. Riederer, Germany

J. Deckert, Germany; M. Gamer, Germany; P. Pauli, Germany; P. Riederer, Germany;

M. Romanos, Germany

Scientific Committee

Chairs: H. C. Pape and A. J. Fallgatter, Germany

Scientific Committee WASAD

E. Binder, Germany, A.J. Fallgatter, Germany, J. Fayyad(†), Beirut, C. Jacob, Germany, J. Li, China,

H. Ozawa, Japan, A. Reif, Germany, T. Renner, Germany, P. Riederer, Germany, E. Seifritz,

Switzerland, S. Walitza, Switzerland

Scientific Committee SFB-TRR 58

C. Büchel, Germany, U. Dannlowski, Germany, K. Domschke, Germany, J. Haaker, Germany, C.

Heim, Germany, M. Gamer, Germany, K. Jüngling, Germany, H.C. Pape, Germany, P. Pauli,

Germany

Congress Information

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Session formats

Keynote Lectures

Keynote lectures of 60 minutes will be given by a distinguished and renowned expert and will

be devoted to a specific topic of major interest.

Symposia

These sessions of 90 minutes will focus on a particular topic and present the very latest data

related to it. The symposia will include four speakers who present their research followed by

discussion. These sessions will combine presentations by invited speakers and the best

submitted papers accepted for the congress by the scientific committees.

Posters

Authors present their latest research findings or ongoing research as posters.

Industry Sponsored Sessions

Industry sponsored sessions of 60 minutes are organized by the industry in consultation with

the scientific committee.

Information for speakers: We kindly ask all speakers to come to their assigned room 15 minutes before the session starts.

Please have your presentation ready in MS Powerpoint format on a USB stick. Please do not

bring your own laptop.

Someone will be available to assist you with uploading your presentation.

Information for poster presenters: We kindly ask all poster presenters to mount their poster on

Thursday, October 3rd, 13.15 - 17.00 or on Friday, October 4th, 08.15 - 11.00.

Assistance and mounting material (poster strips) are available.

Please see detailed program (p. 10) for the time you are requested to be present at your poster.

The posters can remain on display until Saturday, October 5th, 18.30 (removal by the author is

possible on Saturday afternoon), and will be removed by the organizers afterwards.

Three posters will be selected for a WASAD Poster Award (Award Ceremony during Closing

Session).

Rooms:

HS 0.001, HS 0.002 - ground floor

SR 1.012, SR 1.003 - 1st floor

CME points:

The scientific program of the congress is certified by the Bayerische Landesärztekammer (BLÄK)

with 22 CME points. Certificates can be obtained at the registration desk.

Please note that only presenting authors are stated in the program due to space restrictions. All

authors will be named in the printed abstracts.

Congress Information

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Thursday Oct 3rd

HS 0.001 HS 0.002 SR 1.012 SR 1.003

14.00-14.30

Opening ceremony, Welcome addresses

15.00-16.30

New insights into (dys-) regulation of fear and anxiety in rodents

Clinical perspectives in the treatment of anxiety disorders (GAF-Symposium)

Imaging of stress-induced brain functional changes

17.00-18.00

Keynote lecture by Rachel Yehuda

18.00-20.00

Welcome reception at the congress venue

Friday Oct 4th

HS 0.001 HS 0.002 SR 1.012 SR 1.003

09.00-10.00

Keynote lecture by Mathias Schmidt

10.30-12.00

How anxiety modulates attention

Stress resilience and vulnerability

Mapping mechanisms of gene x environment interaction in stress - from endophenotype to disease

12.15-13.15

Industry symposium

13.30-14.30

Keynote lecture by Martin Paulus

14.30-17.00

Poster session 15.30-16.30: WASAD General Assembly

17.00-18.30

Anxiety Disorders - Prediction, prevention and personalized therapy

Stress and dementia SGAD Symposium

Program overview

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Saturday Oct 5th

HS 0.001 HS 0.002 SR 1.012 SR 1.003

09.00-10.00

Keynote lecture by Brenda Penninx

10.30-12.00

Individual differences in fear and anxiety

Temperament, gene and nutrition in anxiety and related disorders

Clinical targets for stress related and anxiety disorders in children and adolescents

12.15-13.15

Industry symposium

Meeting of SFB TRR 58 members

13.30-14.30

Keynote lecture by Thomas Kash

15.00-16.30

Neural dynamics of aversive learning

(Maternal) Stress and its consequences: from animals to humans

Anxiety, depression and cognition in brain and heart

17.00-18.30

Telemedicine and mobile assessment in stress related disorders

Anxiety: genetics, social interactions and therapy

Adult ADHD and stress: cause or consequence?

18.45-19.00

Closing ceremony

Program overview

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Dear colleagues,

The World Association for Stress-Related and Anxiety Disorders (WASAD) aims to promote basic

research and to foster effective and safe treatments and prevention strategies for mental

illnesses related to abundant stress and anxiety. Such illnesses include depression, panic

disorders, social anxiety disorders, specific phobias or separation anxiety disorders, PTSD,

ADHD, sleep disorders and others. These are the most prevalent mental disorders and they are

definitely related to increased levels of stress and associated with immense health care costs

and a high burden of disease.

According to large population-based surveys, roughly one third of the population is affected by

an anxiety disorder during their lifetime. Substantial underrecognition and undertreatment of

these disorders have been shown and recent efforts underline the importance of resilience.

Untreated, stress related and anxiety disorders frequently follow a chronic course, and they are

highly comorbid with other mental disorders, in particular with affective and substance abuse

disorders. While research on pathophysiological mechanisms as well as diagnosis and treatment

made substantial progress during the last years, translation into clinical practice is still lacking

behind.

At this joint conference, WASAD and the "SFB-TRR 58, Fear, Anxiety, Anxiety Disorders” offer a

total of 23 scientific sessions addressing those problems and provide a forum for scientists,

clinicians, practicing physicians, psychotherapists, PostDocs and PhDs, students and other

health care professionals to exchange knowledge and experiences in the fields of basic and

clinical research and to transfer this information into successful clinical applications for the

benefit of our patients.

In this sense, we wish you all a fruitful and stimulating conference!

Yours sincerely,

Prof. Dr. Peter Riederer Prof. Dr. Andreas J. Fallgatter Prof. Dr. Hans-Christian Pape

President WASAD Vice-President WASAD Coordinator SFB-TRR 58

and Congress President and Congress President

Welcome address

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14.00 - 14.30 | Opening Ceremony

HS 0.002

Welcome Addresses

Alfred Forchel, President, University of Würzburg

Matthias Frosch, Dean, Faculty of Medicine, University of Würzburg

Andreas Fallgatter, Congress President

Hans Christian Pape, Congress President

Peter Riederer, President WASAD

15.00 - 16.30 | Parallel Sessions

HS 0.001

SFB Symposium | New insights into (dys-) regulation of fear and anxiety in rodents

Chair: Andreas Draguhn, Heidelberg, and Hans-Christian Pape, Münster

15.00 Gal Richter-Levin Studying neural mechanisms of stress vulnerability and

resilience in an animal model of PTSD

15.20 Philip Tovote Brainstem circuits mediating behavioral and autonomic

defensive states

15.40 Kay Jüngling Novel vistas on Neuropeptide S-mediated fear regulation from

a humanized mouse model

16.00 M. S. Fustiñana Encoding of social information by subpopulations of amygdala

neurons

HS 0.002

WASAD Symposium | Clinical perspectives in the treatment of anxiety disorders

(Symposium of the GAF)

Chair: Katharina Domschke, Freiburg, and Peter Zwanzger, Wasserburg

15.00 Andreas Ströhle D-cycloserine (DCS) adjunct treatment in combination with

cognitive behavioral therapy (CBT)

15.20 Miriam Schiele Prevention of anxiety disorders

15.40 Martin Herrmann Non-invasive brain-stimulation and its impact on extinction

learning

16.00 Julia Diemer Virtual reality as a new tool for the treatment of anxiety

Scientific Program – Thursday, October 3rd

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SR 1.012

WASAD Symposium | Imaging of stress-induced brain functional changes

Chair: Martin Walter, Jena, and Andreas J. Fallgatter, Tübingen

15.00 Marie-José van

Tol Imaging stress effects in depression and anxiety

15.20 Martin Walter Imaging of stress-induced brain functional changes

15.40 Janna Marie Bas-

Hoogendam

Neuroimaging results from the Leiden Family Lab study on

Social Anxiety Disorder: a multiplex, multigenerational

endophenotype study

16.00 Niklas Siminski Temporal unpredictability increases BNST and Amygdala

activity during threat processing

17.00 - 18.00 | Keynote Lecture HS 0.001

Chair: Elisabeth Binder, Munich

Rachel Yehuda, New York

Intergenerational effects of trauma

18.00 - 20.00 | Welcome Reception

Ground floor

Scientific Program – Thursday, October 3rd

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9.00 - 10.00 | Keynote Lecture HS 0.001

Chair: Norbert Sachser, Münster

Mathias Schmidt, Munich

Ramping up stress resilience: Genetic and environmental factors

10.30 - 12.00 | Parallel Sessions

HS 0.001

SFB Symposium | How anxiety modulates attention

Chair: Herta Flor, Heidelberg, and Matthias Gamer, Würzburg

10.30 Ernst Koster How to conceptualize, measure, and modify anxiety-related

attentional bias

10.50 Matthias Wieser Fear and anxiety in the visual brain - Differential visuocortical

processing of predictable and unpredictable threat

11.10 Dean Mobbs Space, time and anxiety: Survival decisions along defensive

circuits

11.30 Kati Roesmann Fear generalization of implicit conditioned facial features –

Behavioral and magnetoencephalographic correlates

HS 0.002

WASAD Symposium | Stress resilience and vulnerability

Chair: Annamaria Cattaneo, London, and Marco A. Riva, Milano

10.30 Annamaria

Cattaneo

Role of miRNA19 in the mechanisms associated with stress

vulnerability and stress resilience

10.50 Marco A. Riva Molecular signatures of prenatal stress exposure and

relevance for the susceptibility and resilience to mental illness

11.10 Hina Ghafoor Stress reactivity in individuals with high vs low interoceptive

accuracy

11.30 Soraya Seedat

Long-term effectiveness of prolonged exposure for adolescents

with PTSD using a task-shifted intervention: Randomised

controlled trial with supportive counselling as a comparator

Scientific Program – Friday, October 4th

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SR 1.003

WASAD Symposium | Mapping mechanisms of gene x environment interaction in stress -

from endophenotype to disease

Chair: Elisabeth Binder, Munich, and Thora Halldorsdottir, Reykjavik

10.30 Thora

Halldorsdottir

Neurobiology of self-regulation: Longitudinal influence of

FKBP5 early life stress on emotional and cognitive

development in childhood

10.50 Immanuel Elbau

A polygenic score of molecular sensitivity to GR-stimulation

maps to stress related changes of the brains hemodynamic

response function

11.10 Charlotte

Piechaczek

Interactions between FKBP5 variation and environmental

stressors in adolescent major depression

11.30 Alma Džubur

Kulenović

Posttraumatic stress disorder in a war-exposed sample from

Balkan countries: The impact of (epi-) genetic variation on

disease susceptibility and the severity of symptoms

12.15 - 13.15 | Industry Sponsored Session

SR 1.012

13.30 - 14.30 | Keynote Lecture HS 0.001

Chair: Paul Pauli, Würzburg

Martin Paulus, Tulsa

Computational models of anxiety

14.30 - 17.00 | Poster Session

Open areas on 1st and 2nd floor

List of posters: see pages 19-23

Posters with even numbers are to be presented between 14.30 and 15.45,

posters with odd numbers are to be presented between 15.45 and 17.00.

Scientific Program – Friday, October 4th

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17.00 - 18.30 | Parallel Sessions

HS 0.001

SFB Symposium | Anxiety Disorders – Prediction, prevention and personalized therapy

Chair: Andreas Papassotiropoulos, Basel, and Katharina Domschke, Freiburg

17.00 Vijaya

Manicavasagar

Separation anxiety grows up: an overview of separation

anxiety in adults

17.20 Marcel Romanos Developmental fear generalization

17.40 Katharina

Domschke Epigenetics of anxiety

18.00 Heike Weber Genetic variability of GLRB impact cognitive behavioral

therapy response in panic disorder

HS 0.002

WASAD Symposium | Stress and dementia

Chair: Peter Riederer, Würzburg, and Frank Jessen, Cologne

17.00 Frank Jessen The role of stress in the development of dementia

17.20 Paul J. Lucassen Early life stress and its programming effects and lasting

consequences

17.40 Ana Babić Perhoč

Stress and neuroinflammation as possible mediators of acute

cognitive dysfunction in a streptozotocin-induced rat model of

sporadic Alzheimer’s disease

18.00 Thomas Polak Anxiety in old age – data of the Vogel study

Scientific Program – Friday, October 4th

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SR 1.003

WASAD Symposium | Symposium of the SGAD (Schweizerische Gesellschaft für Angst und

Depression)

Chair: Erich Seifritz, Zurich, and Susanne Walitza, Zurich

17.00 Birgit Kleim Predictors of stress resilience

17.20 Boris Quednow

The effect of psychosocial and craving-induced stress on social

cognition and decision-making in cocaine users: a longitudinal

approach

17.40 Reto Huber The relationship between sleep and brain plasticity and its

relevance for psychiatric disorders

18.00 Hans Kalkmann Preclinical view on the mechanism of antidepressant activity of

eicosapentaenoic acid

Scientific Program – Friday, October 4th

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9.00 - 10.00 | Keynote Lecture HS 0.001

Chair: Marcel Romanos, Würzburg

Brenda Penninx, Amsterdam

Towards reducing the public health impact of anxiety disorders

10.30 - 12.00 | Parallel Sessions

HS 0.001

SFB Symposium | Individual differences in fear and anxiety

Chair: Tina Lonsdorf, Hamburg, and Ulrike Lüken, Berlin

10.30 Isaac R. Galatzer-

Levy

Hacking behavior to understand brain based disorders: the role

of computation to re-define clinical phenotypes

10.50 Kevin Hilbert

Using individual differences to construct machine learning

based models for single-subject classification and prediction in

anxiety and related disorders

11.10 Elisabeth Leehr

Theranostic markers for personalized therapy of spider phobia:

Methods of a bicentric external cross-validation machine

learning approach

11.30 Mario Reutter Do individual patterns of attentional exploration predict

differences in fear generalization?

Scientific Program – Saturday, October 5th

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HS 0.002

WASAD Symposium | Temperament, gene and nutrition in anxiety and related disorders

Chair: Hiroki Ozawa, Nagasaki, and Takeshi Inoue, Tokyo

10.30 Ken Yonezawa Relationship between omega-3 fatty acid and mental disorder

10.50 Yoshirou

Morimoto

Gene-based rare variants association test implicates PLA2G4E

as a risk gene for panic disorder

11.10 Takeshi Inoue Temperaments, child abuse and stressful events in anxiety and

related disorders

11.30 Jie Li Gene polymorphisms are associated with treatment-resistant

depression in Han Chinese

SR 1.012

WASAD Symposium | Clinical targets for stress related and anxiety disorders in children and

adolescents

Chair: Susanne Walitza, Zurich, and Lizbeth Utens, Amsterdam

10.30 Edna Grünblatt The link between the genetic risk load, anxiety and stress in

individuals at clinical high risk for psychosis

10.50 Lizbeth Utens

Anxiety in children with somatic conditions: outcome of CBT

and EMDR for the clinical targets IBD and congenital heart

disease

11.10 Ulrike Schmidt Potential DNA methylation and miRNA markers for

posttraumatic stress disorder (PTSD)

11.30 Madlena

Arakelyan Psychological risk factors of gifted adolescents

12.15 - 13.15 | Industry Sponsored Session

HS 0.002

Scientific Program – Saturday, October 5th

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13.30 - 14.30 | Keynote Lecture HS 0.001

Chair: Christian Büchel, Hamburg

Thomas Kash, Chapel Hill

The role of the extended amygdala in alcohol-drinking driven alterations in threat response

15.00 - 16.30 | Parallel Sessions

HS 0.001

SFB Symposium | Neural dynamics of aversive learning

Chair: Marta Andreatta, Würzburg, and Jan Haaker, Hamburg

15.00 Andreas Olsson Social learning and decision making under threat

15.20 Lauren Atlas Dissociable influences of anxiety on pain and arousal during

aversive reversal learning

15.40 Ute Habel Influencing and modulating factors of aggression and

impulsivity

16.00 Christian Büchel Neural mechanisms of fear generalization

HS 0.002

WASAD Symposium | (Maternal) Stress and its consequences: from animals to humans

Chair: Birgit Derntl, Tübingen, and Andreas J. Fallgatter, Tübingen

15.00 Liisa Galea Stress effects in postpartal depression

15.20 Birgit Derntl Stress and its consequences on cognition and emotion in

women and men

15.40 Maya Meentken Psychological outcomes after pediatric hospitalization: the role

of trauma type

16.00 Thorsten Mikoteit Truth lies in the hair: Prenatal hair steroids predict postpartum

depression

Scientific Program – Saturday, October 5th

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SR 1.012

WASAD Symposium | Anxiety, depression and cognition in brain and heart

Chair: Jürgen Deckert, Würzburg, and Stefan Frantz, Würzburg

15.00 Andreas Menke Investigating the brain-heart connection: the Depression

Associated Cardiac Failure (DACFAIL) Study

15.20 Stefan M. Schulz

A web-based intervention for improving psychosocial distress

in heart failure patients with an implantable cardioverter

defibrillator

15.40 Sarah Kittel-

Schneider

Anxiety, depression and heart function – The genetic

connection

16.00 Anna Frey Cognition matters in patients with chronic heart failure

17.00 - 18.30 | Parallel Sessions

HS 0.001

WASAD Symposium | Telemedicine and mobile assessment in stress related disorders

Chair: Tobias J. Renner, Tübingen, and Gudmundur Skarphedinsson, Reykjavik

17.00 Karsten Hollmann E-health interventions in pediatric OCD

17.20 Gudmundur

Skarphedinsson

Developing and implementing iCBT for pediatric obsessive-

compulsive disorder in Iceland

17.40 Sonja Kleih An online based stress management intervention for patients

with Parkinson’s disease

18.00 Kati Roesmann

Clinical, behavioral and magnetoencephalographic correlates

of fear generalization before and after virtual reality exposure

therapy in spider phobia

Scientific Program – Saturday, October 5th

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HS 0.002

WASAD Symposium | Anxiety: genetics, social interactions and therapy

Chair: Grit Hein, Würzburg, and Manuel Mattheisen, Würzburg

17.00 Manuel

Mattheisen

OCD genetics: updates from the Danish OCD and Tourette’s

study and the Psychiatric Genomics Consortium

17.20 Angelika Erhardt Genetics and epigenetics of panic disorder

17.40 Grit Hein Social buffering of anxiety

18.00 André Pittig Expectancy violation as mechanism of change in exposure-

based cognitive-behavioural therapy

SR 1.012

WASAD Symposium | Adult ADHD and stress: cause or consequence?

Chair: Christian Jacob, Esslingen, and Gara Arteaga Henríquez, Barcelona

17.00 Gara Arteaga

Henríquez Cortisol awakening response and ADHD

17.20 Corina Greven ADHD and stress-reducing psychotherapy

17.40 Francisco Esteves Attention, eating disorders and body dissatisfaction

18.00 Sarah

Kittel-Schneider Chronic stress and quality of life in adult ADHD

18.45 - 19.00 | Closing Ceremony

HS 0.002

Awards Ceremony for poster awards

Closing remarks

Peter Riederer, Germany

Scientific Program – Saturday, October 5th

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Keynote speakers

Thomas Kash, Chapel Hill

Martin Paulus, Tulsa

Brenda Penninx, Amsterdam

Mathias Schmidt, Munich

Rachel Yehuda, New York

Speakers in plenary symposia

(listed in alphabetical order)

Madlena Arakelyan, Yerevan

Lauren Atlas, Bethesda

Ana Babić Perhoč, Zagreb

Janna Marie Bas-Hoogendam, Leiden

Christian Büchel, Hamburg

Annamaria Cattaneo, London

Birgit Derntl, Tübingen

Julia Diemer, Wasserburg

Katharina Domschke, Freiburg

Alma Džubur Kulenović, Sarajevo

Immanuel Elbau, Munich

Angelika Erhardt, Munich

Francisco Esteves, Östersund

Anna Frey, Würzburg

M. S. Fustiñana, Basel

Liisa Galea, Vancouver

Isaac R. Galatzer-Levy, New York

Hina Ghafoor, Würzburg

Corina Greven, Nijmegen

Edna Grünblatt, Zurich

Ute Habel, Aachen

Thora Halldorsdottir, Reykjavik

Grit Hein, Würzburg

Gara Arteaga Henríquez, Barcelona

Martin Hermann, Würzburg

Kevin Hilbert, Berlin

Karsten Hollmann, Tübingen

Reto Huber, Zurich

Takeshi Inoue, Tokyo

Frank Jessen, Cologne

Kay Jüngling, Münster

Hans Kalkmann, Basel

Sarah Kittel-Schneider, Würzburg

Sonja Kleih, Würzburg

Birgit Kleim, Zurich

Ernst Koster, Ghent

Elisabeth Leehr, Münster

Jie Li, Tianjin

Paul J. Lucassen, Amsterdam

Vijaya Manicavasagar, Sydney

Manuel Mattheisen, Würzburg

Maya Meentken, Rotterdam

Andreas Menke, Würzburg

Thorsten Mikoteit, Solothurn

Dean Mobbs, Pasadena

Yoshirou Morimoto, Nagasaki

Andreas Olsson, Stockholm

Charlotte Piechaczek, Munich

Andre Pittig, Würzburg

Thomas Polak, Würzburg

Boris Quednow, Zurich

Gal Richter-Levin, Haifa

Mario Reutter, Würzburg

Marco Riva, Milano

Marcel Romanos, Würzburg

Kati Roesmann, Münster

Miriam Schiele, Freiburg

Ulrike Schmidt, Göttingen

Stefan M. Schulz, Würzburg

Soraya Seedat, Stellenbosch

Niklas Siminski, Würzburg

Gudmundur Skarphedinsson, Reykjavik

Andreas Ströhle, Berlin

Marie-José van Tol, Utrecht

Philip Tovote, Würzburg

Lizbeth Utens, Amsterdam

Martin Walter, Jena

Heike Weber, Würzburg

Matthias Wieser, Rotterdam

Ken Yonezawa, Nagasaki

Speakers

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Poster Session | Friday, October 4th, 14.30 - 17.00

Posters with even numbers are to be presented between 14.30 and 15.45,

posters with odd numbers are to be presented between 15.45 and 17.00.

Group A

1 Hessel, Margarita Münster Serotonergic system of the anterodorsal BNST is involved in phasic and sustained fear in freely behaving mice

2 Krakenberg, Viktoria

Münster Effect of serotonin transporter deficiency on the cognitive judgment bias of mice

3 Remmers, Floortje

Mainz

Towards highly specific genetic manipulation of the mouse cannabinoid CB1 receptor using CRISPR/Cas9: cell-type selective and region-specific CB1 knockout in the adult brain and generation of a CB1 point-mutation mouse line

4 Kästner, Niklas Münster Brain serotonin deficiency affects female aggression

5 Fiedler, Dominik Münster Impact of Brain-Derived Neurotrophic Factor on synaptic transmission and plasticity in the oval nucleus of Bed Nucleus of the Stria Terminalis

6 Hepbasli, Denis Würzburg OCD and neurodegeneration in SPRED2-deficient mice is associated with brain ventricle enlargement and ultrasonic vocalization changes

7 Jamil, Sara Münster Local deletion of Y2 receptors in BNSTav mediates extinction and return of remote fear memory

8 Hamann, Catharina

Würzburg Altered expression of genes related to the vasopressin and oxytocin brain systems: A study with 5-HTT deficient mice after experiencing prenatal stress

9 Zöller, Johanna Würzburg Stress-induced epigenetic programming in serotonin transporter deficient mice: Epigenetic editing – a strategy to cope with anxiety

10 Goedecke, Lena Münster A human relevant polymorphism in the Neuropeptide-S receptor (NPSR1 I107N) alters receptor signaling and fear-related behavior in mice

11 Cortes Cortes,

Orlando Jose Würzburg

Neuroanatomical tracing of glutamatergic brainstem circuits for behavioral and autonomic defense responses

12 Signoret-Genest, Jérémy

Würzburg Brainstem circuits for cardiac interoception and control of defensive states

13 Jüngling, Kay Münster Impact of the human neuropeptide-S receptor polymorphism (I107N) on fear and anxiety in mice

Posters

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Group B

14 Fňašková, Monika Brno, Czech Republic

Life-long effects of extreme stress on brain structures – a holocaust survivor MRI study

15 Sperl, Matthias Marburg Temporal dynamics of threat processing: Modulation of event-related potential components during a sequential-set fear acquisition paradigm

16 Vietz, Melanie Würzburg Anxiety sensitivity as a modulator of fear generalization in healthy adults

17 Berking, Ann-Cathrine

Würzburg The role of DNA methyltransferases in anxiety disorders

18 Kollert, Leonie Würzburg The TGFB-Inducible Early Growth Response Protein 2 (TIEG2) gene as a new candidate in the etiology of panic disorder?

19 Segebarth, Dennis Würzburg Deep learning can increase the reliability, objectivity, reproducibility and transparency in image data analysis

20 Becker, Michael Münster Reward prediction error signaling during reinforcement learning in social anxiety disorder is altered by social observation

21 Nieratschker, Vanessa

Tübingen Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms

22 Slyschak, Anna Würzburg Fear generalization in children and adolescents: a cross-sectional study across ages

23 Stegmann, Yannik Würzburg Investigating attentional mechanisms during the interaction of phasic fear and sustained anxiety

24 Klinke, Christopher M.

Würzburg Distal stress induction facilitates fear memory consolidation

25 Krylova, Marina Tübingen Nx4 effect on stress-induced changes in EEG frequency powers

26 Wessing, Ida Münster Magnetoencephalographic correlates of fear generalization in adolescence

27 Riepl, Korbinian Würzburg Early negative attentional bias in persons with high depressive symptoms during a facial oddball task

28 Muehlhan, Markus

Hamburg Dose-dependent effects of cortisol on functional large-scale connectivity of the visual cortex

29 Avetyan, Diana Yerevan, Armenia

Association between rs734194 genetic variant of nerve growth factor receptor (NGFR) and peripheral telomere length with posttraumatic stress disorder

30 Rösler, Lara Würzburg Freezing of gaze supports action preparation under threat imminence

Posters

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31 Hohoff, Christa Münster Adenosine A1 receptor availability in healthy human brains: Modulation by interacting adenosinergic gene variants and sleep habit in anxiety-related brain regions

32 Weber, Heike Würzburg Allelic variation in PPID predisposes to anxiety disorders

33 Ridderbusch, Isabelle Caroline

Marburg Stability and reliability of the delayed extinction fMRI-paradigm of the multicentric trial PROTECT-AD

34 Leimeister, Franziska

Würzburg Subsequent memory effects in threat and safety learning

35 Schneider, Sarah Würzburg Modulation of pain by social stress - the role of positive and negative feedback

36 Herzog, Katharina Würzburg Reducing Generalization of Conditioned Fear: comparison of a fear-specific discrimination training with fear-unrelated control tasks

37 Merscher, Alma-Sophia

Würzburg Freezing of gaze in conditions that require distributed attention

38 Zillig, Anna-Lena Würzburg The influence of learned safety on pain perception

39 Boschet, Juliane Würzburg Temporal dynamics of costly avoidance in newly acquired fears

40 Winkler, Markus Würzburg Context conditioning and extinction in virtual reality: effects on self-report in anxiety patients

41 Glück, Valentina Marburg Habitual and goal-directed avoidance behavior: associations with trait anxiety

42 Smigielski, Lukasz Zurich, Switzerland

Associations between the genetic burden, anxiety and stress in the at-risk state for psychosis

43 Dubberke, Anne Trier

Sleep quality and salivary biomarkers: A pilot study connecting the cortisol awakening response and the dim light melatonin onset with an overnight polygraphy assessment

Posters

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Group C

44 Klement, Stephan Karlsruhe Single or multiple dose applications of Silexan do not impair fitness to drive – results from a placebo-controlled crossover trial

45 Asbrand, Julia Freiburg Repeated stress leads to enhanced cortisol stress response in child social anxiety disorder but this effect can be prevented with CBT

46 Kreifelts, Benjamin

Tübingen The neural correlates of face-voice-integration in social anxiety disorder

47 Seeger, Fabian Würzburg Associations between resting state connectivity, symptom severity and within-session extinction in the treatment of spider phobia

48 Schwarzmeier, Hanna

Würzburg Brain-morphometric predictors of within-session extinction during behavioral exposure in spider phobia

49 Goede, Wolfgang Munich Work tandems of psychiatry and anxiety self-help: Can research and society benefit from the collaboration of academic experts and experience experts?

50 Hasanagic, Senad

Sarajevo, Bosnia and Herze-govina

Combination of aripiprazole and clozapine in first episode of psychosis and metabolic syndrome: report of five cases

51 Baumgartner, Noemi

Zurich, Switzerland

Inter-informant agreement of the Children’s Depression Rating Scale Revised in depressed children and adolescents

52 Junghöfer, Markus

Münster Excitatory transcranial direct current stimulation of the anterior ventromedial prefrontal cortex reveals add-on effects for the therapy of Major Depressive Disorder (MDD)

53 Li, Pan Tianjin, China

The comparative analysis of cognitive function and neuropsychiatric behavior between Alzheimer's disease and frontotemporal dementia patients

54 Scherf-Clavel, Maike

Würzburg How smoking cigarettes affects the serum concentrations of escitalopram

55 Scherf-Clavel, Maike

Würzburg Baseline HPA axis activity predict improvement in HPA axis function during antidepressant treatment

56 Lellouch, Laurent Paris, France

Vocal markers of pre-operative anxiety: a pilot study

57 Häberling, Isabelle

Zurich, Switzer-land

Anxious depression as a clinically relevant subtype of pediatric major depressive disorder

58 Herrmann, Martin Würzburg Non-invasive brain stimulation augments fear extinction

59 Breisinger, Sarah Würzburg

Association of pain relief for chronic musculoskeletal pain after interdisciplinary multimodal pain treatment (IMPT) with serum concentrations of antidepressant drugs in a real-life analysis

60 Li, Shen Tianjin, China

The prevalence, risk factors of burnout in Chinese preschool teachers

Posters

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61 Sauter, Amelie Würzburg Heart rate variability associated with suicidality in depressed patients

62 Li, Jie Tianjin, China

Suicide rates changing in China and suicide prevention in Tianjin

63 Weber, Heike Würzburg Genetic variability of GLRB impact cognitive behavioral therapy response in panic disorder

64 Ziebell, Philipp Würzburg

Transcranial ultrasound neuromodulation as a new potential intervention for affective disorders - Recent findings and ideas for the future from a differential psychology perspective

65 Pfaffinger, Katharina F.

Munich Development and test of a new scale for the measurement of digital anxiety

66 Hellmuth, Anna Würzburg SGK1 signaling predict response in major depression

67 Andri, Andri Jakarta, Indonesia

Somatic Symptoms in Depression: Indonesian Perspective

68 Hock, Anja Würzburg Microdeletion syndrome 22q11.2 – Clinical and Molecular Characterization of a High-Risk Cohort

69 Wambura, Matiko Mwanza, Tanzania

Treatment overview of mentally ill patients at Bugando Medical Centre in Mwanza, Tanzania with a focus on PTSD, Depression and Anxiety

70 du Plessis, Stéfan

Stellen-bosch, South Africa

Childhood trauma and hippocampal subfield volumes in first-episode schizophrenia and healthy controls

Three poster award winners – one from each group, in order to represent the entire spectrum

of topics – will be selected by the award committee:

R. Blum, Würzburg; A. Fallgatter, Tübingen; J. Haaker, Hamburg; M. Herrmann, Würzburg;

C. Jacob, Esslingen; S. Kittel-Schneider, Würzburg; T. Lonsdorf, Hamburg; U. Lüken, Berlin;

A. Ströhle, Berlin

Posters

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Registration and Organizer of the Industrial Exhibition & Sponsoring INTERPLAN

Congress, Meeting & Event Management AG

Project Management: Jasmin Greger

Landsberger Strasse 155

80687 Munich, Germany

Phone +49 (0) 89 54 82 34 62

Fax +49 (0) 89 54 82 34 62

[email protected]

Opening Hours of the registration counter 3 October 2019: 10.00 – 18.30

4 October 2019: 08.00 – 19.00

5 October 2019: 08.00 – 19.00

The registration desk is open for registration and assistance during the above mentioned

opening hours. Onsite registration is possible at the registration counter. Registration fees can

be paid in cash or via credit card. Registration for single days is not possible.

Registration Fees

Regular Registration Fee: € 390

Student Fee*: € 70

SFB Members/GAF Members**: € 180

*Only valid for full time students who have not finished their studies yet before the congress starts. A valid/current

student ID copy or letter from advisor is required.

**Validity of membership will be checked

Name Badge Please wear your name badge for the entire duration of the congress. It serves as your entrance

ticket.

Opening Hours of the industrial exhibition 3 October 2019: 13.30 – 18.00

4 October 2019: 08.30 – 18.30

5 October 2019: 08.30 – 17.00

General Information

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Catering: Coffee, cold drinks, snacks, and a light lunch are available in the catering area on the 2nd floor.

Changes of schedule at short notice: In case of necessary changes of schedule at short notice (cancellation or time changes of single

talks or sessions, change of speaker), the registration fee cannot be refunded.

WiFi: Free WiFi is available at the congress site either via “eduroam” (if set up by your home

university) or via “BayernWLAN” (free WIFI, no password necessary).

Data Protection Interplan handles all personal data according to the laws of the EU-Data Protection Regulation

(EU-GDPR) and the Federal Data Protection Act (BDSG New). For your booking within the above

mentioned congress the collecting, saving and processing of your personal data is imperative.

This is done solely as a means of the organization and completion of the event. We will collect

your data on behalf of the World Association for Stress Related and Anxiety Disorders e.V.

(WASAD), Schwanenhof 4, 97070 Würzburg, Germany.

Your data will only be passed onto a third party who is directly involved with the running of the

Congress and when the organizational procedure makes this necessary (operator, hotel). The

registration to this congress is not possible if we do not get this.

For a complete overview of the applicable privacy policy, see the following Link:

https://www.interplan.de/en/data-protection.php#datasec

General Information

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Congress Venue: Zentrales Hörsaal- und Seminargebäude Z6, Am Hubland, 97074 Würzburg

Map data © OpenStreetMap contributors

Bus from Würzburg Hauptbahnhof (main station):

Line 114 – direction “Hubland” – to stop „Hubland/Mensa“

Line 214 – direction “FHWS” – to stop „Hubland/Mensa “

Bus from Sanderring (stop „Sanderglacisstraße“):

Line 10 – direction “Sprachenzentrum/Campus Nord” – to stop „Hubland/Mensa“

Taxi dispatch Würzburg:

Phone +49 931 19410

General Information

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Society Profile The World Association for Stress-related and Anxiety Disorders, WASAD, is an independent non-

profit organization founded in 2016 by leaders of clinical and translational science.

Board: President: Prof. Dr. P. Riederer, Würzburg

Vice-President: Prof. Dr. A. Fallgatter, Tübingen

Secretary: Prof. Dr. T. Renner, Tübingen

Treasurer: Prof. Dr. C. Jacob, Esslingen

WASAD has set itself the goal:

To promote basic research on stress-related and anxiety disorders

To ensure effective and safe drug treatment and prevention strategies for these mental

illnesses

To make the interdisciplinary scientific findings suitable for clinical and psychological

institutions and their representatives

To offer the right framework for clinicians and practicing physicians, psychotherapists,

physicians and psychotherapists in training, students and health care professionals in

order to exchange knowledge and experiences in the fields of clinical and basic research,

stress, stress-related and anxiety disorders

To make recommendations to current therapy-relevant topics

To promote international contacts in this field

About WASAD

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The support of the following sponsors and exhibitors is gratefully acknowledged:

Sponsors

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Sponsors

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Sponsors

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Friday, 12.15 - 13.15 | Industry Sponsored Session

SR 1.012

Heel Symposium | Imaging All the data – what can and what can’t we get from

pharmacological and other interventional brain imaging studies on

stress and anxiety?

Chair: Martin Walter, Jena

12.15 Rupert

Lanzenberger

Chances and limitation for Multimodal MRI and PET imaging

studies on pharmacological mechanisms

12.35 Martin Walter Resting state and task fMRI insights on mechanisms of

mediation and complex therapeutics

12.55 Steven Williams Limitations and lessons learned from brain imaging studies –

implications for studies of stress and anxiety

Saturday, 12.15 - 13.15 | Industry Sponsored Session

HS 0.002

Janssen Symposium | Depression and Suicidality - from Neurobiology to clinical practice

Chair: Martin Walter, Jena, and Claus Normann, Freiburg

12.15 Claus Normann Depression

12.45 Martin Walter Suicidality

Industry Sponsored Sessions

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Industrial Exhibition

Exhibitor Booth Number

Akademische Buchhandlung Knodt 5

daacro-Contract Research & Saliva Lab Trier 2

Heel GmbH 6

Janssen 4

neuraxpharm Arzneimittel GmbH 3

Recordati Pharma GmbH, Ulm 1

Schwabe Pharma Deutschland 7

Sponsors

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Disclosure

As organizer of the industrial exhibition, Interplan AG is obliged to disclose all sums received by

sponsors and exhibitors in order to comply with the regulations of the Bayerische

Landesärztekammer (BLÄK). For the industry partners mentioned below, we are herewith

informing about their overall support within the framework of the WASAD Congress 2019*.

Company Total Amount

daacro-Contract Research & Saliva Lab Trier 1.000,00 €

Heel GmbH 16.000,00 €

Janssen 15.000,00 €

neuraxpharm Arzneimittel GmbH 1.500,00 €

Recordati Pharma GmbH, Ulm 1.000,00 €

Schwabe Pharma Deutschland 1.000,00 €

*at the time of printing

Furthermore, WASAD wishes to acknowledge the support of

XXXLutz KG

Springer Nature

VENT e.V.

Dr. med. Edda Neele Stiftung

Sponsors

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Sponsors

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For your notes

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www.wasad2019.org


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